Read by QxMD icon Read

Exercise and cognitive function

Qi Zhang, Jianan Hu, Lijiao Wei, Ri Cao, Ruishu Ma, Huimin Song, Yi Jin
BACKGROUND: Mild cognitive impairment (MCI) can be a stage of pre-dementia. Although the traditional Chinese exercise (TCE) has benefits associated with cognitive functions, the effects of the TCE on cognitive functions of older patients with MCI remain controversial. This study performs a meta-analysis to quantify the efficiency of TCE for older individuals on cognitive and psychological outcomes. METHODS: A comprehensive database search was conducted on PubMed, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL), CINAHL (EBSCO), Web of Science, and four Chinese medical databases...
February 2019: Medicine (Baltimore)
Aaron Stares, Mona Bains
BACKGROUND AND PURPOSE: The role of creatine supplementation in young athletes and bodybuilders is well established including ergogenic properties of muscular hypertrophy, strength, power, and endurance. Whether the benefits of creatine supplementation translate to an aging population with moderate training stimulus remains unclear especially in regard to gender, creatine dose, and duration. This systematic review assessed whether creatine supplementation combined with exercise results in additive improvements in indices of skeletal muscle, bone, and mental health over exercise alone in healthy older adults...
February 8, 2019: Journal of Geriatric Physical Therapy
M Schön, Z Kovaničová, Z Košutzká, M Nemec, M Tomková, L Jacková, D Máderová, L Slobodová, P Valkovič, J Ukropec, B Ukropcová
Exercise can prevent the sedentary lifestyle-related risk of metabolic and cognitive decline, but mechanisms and mediators of exercise effects on human brain are relatively unexplored. We measured acute exercise-induced changes in adiponectin, insulin and other bioactive molecules in cerebrospinal fluid (CSF) and serum from young lean individuals. Samples of serum and CSF were obtained before and 1-h after the 90-min run (75-80% HRmax; maximal heart rate), additional serum was taken at finish-line. Body composition, physical fitness, metabolic rate, cognitive functions, food preference, glucose, insulin and albumin were measured...
February 13, 2019: Scientific Reports
Francesca L Guest
Alzheimer's disease affects approximately 6% of people over the age of 65 years. It is characterized as chronic degeneration of cortical neurons, with loss of memory, cognition and executive functions. As the disease progresses, it is accompanied by accumulation of amyloid plaques and neurofibrillary tangles in key areas of the brain, leading to a loss of neurogenesis and synaptic plasticity in the hippocampus, along with changes in the levels of essential neurotransmitters such as acetylcholine and glutamate...
2019: Advances in Experimental Medicine and Biology
Pasquale Caponnetto, Marilena Maglia, Roberta Auditore, Marta Bocchieri, Antonio Caruso, Jennifer DiPiazza, Riccardo Polosa
Cognitive dysfunctions are a common clinical feature of schizophrenia and represent important indicators of outcome among patients who are affected. Therefore, a randomized, controlled, monocentric, singleblind trial was carried out to compare two different rehabilitation strategies adopted for the restoration and recovery of cognitive functioning of residential patients with schizophrenia. A sample of 110 residential patients were selected and, during the experimental period, a group of 55 patients was treated with sets of domain-specific exercises (SRT+CRT), whereas an equal control group was treated with sets of nondomain- specific exercises (SRT+PBO) belonging to the Cogpack® software...
November 6, 2018: Mental Illness
James J Casey, Krista L Harrison, Maria I Ventura, Wolf Mehling, Deborah E Barnes
OBJECTIVES: To understand feedback from participants in Paired PLIÉ (Preventing Loss of Independence through Exercise), a novel, integrative group movement program for people with dementia and their care partners, in order to refine the intervention and study procedures. METHOD: Data sources included daily logs from the first Paired PLIÉ RCT group, final reflections from the second Paired PLIÉ RCT group, and responses to requests for feedback and letters of support from Paired PLIÉ community class participants...
February 12, 2019: Aging & Mental Health
Shengyan Sun, Paul D Loprinzi, Hongwei Guan, Liye Zou, Zhaowei Kong, Yang Hu, Qingde Shi, Jinlei Nie
Background and Objectives : Limited research has evaluated the effects of acute exercise on cognition under different conditions of inspired oxygenation. Thus, the purpose of this study was to examine the effects of high-intensity interval exercise (HIE) under normoxia (inspired fraction of oxygen (FIO₂): 0.209) and moderate hypoxia (FIO₂: 0.154) on cognitive function. Design : A single-blinded cross-over design was used to observe the main effects of exercise and oxygen level, and interaction effects on cognitive task performance...
February 10, 2019: Medicina
Anna Pedrinolla, Massimo Venturelli, Stefano Tamburin, Cristina Fonte, Anna Maria Stabile, Ilaria Boscolo Galazzo, Barbara Ghinassi, Mary Anna Venneri, Francesca Benedetta Pizzini, Ettore Muti, Nicola Smania, Angela Di Baldassarre, Fabio Naro, Mario Rende, Federico Schena
Recent literature highlights the importance of identifying factors associated with mild cognitive impairment (MCI) and Alzheimer's Disease (AD). Actual validated biomarkers include neuroimaging and cerebrospinal fluid assessments; however, we investigated non-Aβ-dependent factors associated with dementia in 12 MCI and 30 AD patients. Patients were assessed for global cognitive function (Mini-Mental state examination-MMSE), physical function (Physical Performance Test-PPT), exercise capacity (6-min walking test-6MWT), maximal oxygen uptake (VO₂max), brain volume, vascular function (flow-mediated dilation-FMD), inflammatory status (tumor necrosis factor-α ,TNF- α, interleukin-6, -10 and -15) and neurotrophin receptors (p75NTR and Tropomyosin receptor kinase A -TrkA)...
February 9, 2019: Journal of Clinical Medicine
Teri Lawton, Ming-Xiong Huang
BACKGROUND: In the U.S. 3.8 million people have a Traumatic Brain Injury (TBI) each year. Rapid brain training exercises to improve cognitive function after a mild TBI are needed. OBJECTIVE: This study determines whether cognitive remediation by discriminating the direction a test pattern moves relative to a stationary background (movement figure-ground discrimination) improves the vision and cognitive deficits that result from a TBI, providing a paradigm shift in treatment methods...
February 5, 2019: Restorative Neurology and Neuroscience
Tim Stuckenschneider, Christopher D Askew, Annelise L Menêses, Ricarda Baake, Jan Weber, Stefan Schneider
BACKGROUND: Supervised exercise training alleviates motor symptoms in people with Parkinson's disease (PD). However, the efficacy of exercise to improve nonmotor symptoms such as cognitive function is less well known. OBJECTIVE: To systematically review evidence on the efficacy of different exercise modes (coordination exercise, resistance exercise, aerobic exercise) on domain-specific cognitive function in patients with PD. METHODS: Parallel-group randomized controlled trials published before March 2018 were included...
2019: Journal of Parkinson's Disease
Yuqiu Ye, Hongyong Liu, Yanbing Chen, Yunqiang Zhang, Shaomin Li, Wentao Hu, Rongqian Yang, Zhesi Zhang, Linsheng Lv, Xun Liu
BACKGROUND: Anemia is extremely common among dialysis patients and underlies some of the symptoms associated with reduced kidney function, including fatigue, depression, reduced exercise tolerance, and dyspnea. OBJECTIVES: A clearer cognition of the prognosistic impact of hemoglobin (Hb) or hematocrit (Hct) target for the outcomes of dialysis patients is urgent. This article aims to establish the suitable hemoglobin in order to provide clinical guidance. METHODS: MEDLINE, EmBase, the Cochrane Library and other databases were searched with both MeSH terms and keywords to gather randomized controlled trials that assessed all-cause mortality, cardiovascular events, fistula thrombosis, infectious diseases and transfusion among dialysis-dependent patients using erythropoiesis-stimulating agents...
November 2018: Renal Failure
Liv-Jorunn Kolnes, Maria Vollsæter, Ola Drange Røksund, Trine Stensrud
Objective: A constricted, upper chest breathing pattern and postural dealignments habitually accompany exercise-induced laryngeal obstruction (EILO), but there are few effective treatments for athletes presenting with EILO. This case series was conducted to examine whether physiotherapy based on principles from the Norwegian psychomotor physiotherapy (NPMP) combined with elements of cognitive behavioural therapy can reduce laryngeal distress in athletes with EILO. Methods: Respiratory distress in four subjects was examined by interview prior to a physiotherapeutic body examination...
2019: BMJ Open Sport & Exercise Medicine
Styliani Douka, Vasiliki I Zilidou, Olympia Lilou, Magda Tsolaki
One of the major problems that elderly people are facing is dementia. For scientist's dementia is a medical, social and economic problem, as it has been characterized as the epidemic of the 21st century. Prevention and treatment in the initial stages of dementia are essential, and community awareness and specialization of health professionals are required, with the aim of early and valid diagnosis of the disease. Activities are recommended to the senior citizens to improve their physical and mental health. Dance has been suggested as an appropriate recreational activity for the elderly that brings functional adjustments to the various systems of the body, psychological benefits, and makes exercise to seem interesting and entertaining as it combines the performance of multiple animations with musical accompaniment...
2019: Frontiers in Aging Neuroscience
Cyril Chatain, Rémi Radel, Fabrice Vercruyssen, Tahar Rabahi, Jean-Marc Vallier, Thierry Bernard, Mathieu Gruet
We aimed to determine the neurophysiological mechanisms associated with reduced endurance performance during cognitive-motor dual task at different levels of cognitive load, compared to a motor task alone. Eighteen healthy men performed isometric quadriceps contractions at 15% of maximal voluntary contraction (blocks of 170 s interspaced by neuromuscular evaluations) until exhaustion. This task was performed on three separate days: (a) in the absence of concomitant cognitive task, (b) with concomitant 1-back task, and (c) with concomitant 2-back task...
February 7, 2019: Psychophysiology
Lauren L Drogos, Katherine Wynne-Edwards, Ruokun Zhou, Samantha E Hall, Amanda V Tyndall, R Stewart Longman, Gail Eskes, Marc J Poulin
Evidence from both preclinical and clinical studies suggests aerobic exercise may dampen age-related decline in cognitive performance. Alterations in hypothalamic-pituitary-adrenal (HPA) axis function and reactivity may be a mechanism by which aerobic exercise benefits cognitive performance, and reduces perceived stress. This investigation was completed as an ancillary investigation of the Brain in Motion (BIM) study, a 6-month supervised aerobic exercise intervention. Participants were generally healthy and screened for inclusion/exclusion criteria for the parent study...
January 19, 2019: Psychoneuroendocrinology
Qiong-Bin Zhu, Ai-Min Bao, Dick Swaab
Alzheimer's disease (AD) is characterized by decreased neuronal activity and atrophy, while hyperactivity of neurons seems to make them resistant to aging and neurodegeneration, a phenomenon which we have paraphrased as 'use it or lose it'. Our hypothesis proposes that (1) during their functioning, neurons are damaged; (2) accumulation of damage that is not repaired is the basis of aging; (3) the vulnerability to AD is determined by the genetic background and the balance between the amount of damage and the efficiency of repair, and (4) by stimulating the brain, repair mechanisms are stimulated and cognitive reserve is increased, resulting in a decreased rate of aging and risk for AD...
February 5, 2019: Neuroscience Bulletin
Ian R E Averill, Ben Beaglehole, Katie M Douglas, Jennifer Jordan, Marie T Crowe, Maree Inder, Cameron J Lacey, Christopher M Frampton, Christopher R Bowie, Richard J Porter
BACKGROUND: Inpatients with depression have a poor long term outcome with high rates of suicide, high levels of morbidity and frequent re-admission. Current treatment often relies on pharmacological intervention and focuses on observation to maintain safety. There is significant neurocognitive deficit which is linked to poor functional outcomes. As a consequence, there is a need for novel psychotherapeutic interventions that seek to address these concerns. METHODS: We combined cognitive activation and behavioural activation to create activation therapy (AT) for the treatment of inpatient depression and conducted a small open label study which demonstrated acceptability and feasibility...
February 1, 2019: BMC Psychiatry
Anna Orban, Bharti Garg, Manoj K Sammi, Dennis N Bourdette, William D Rooney, Kerry Kuehl, Rebecca I Spain
PURPOSE: We determined if a high-intensity aerobic exercise program would be safe, improve expected fitness and clinical outcomes, and alter exploratory phosphorous magnetic resonance spectroscopy (P MRS) outcomes in persons with multiple sclerosis (PwMS). METHODS: This open-label prospective pilot study compared 2 cohorts of ambulatory PwMS matched for age, sex and VO2max. Cohorts underwent 8-weeks of high-intensity aerobic exercise (MS-Ex, n=10) or guided stretching (MS-Ctr, n=7)...
January 30, 2019: Medicine and Science in Sports and Exercise
B Tang, X T Wang, W J Chen, S H Zhu, Y G Chao, B Zhu, W He, B Wang, F F Cao, Y J Liu, X J Fan, H Yang, Q H Xu, H Zhang, R C Gong, W Z Chai, H M Zhang, G Z Shi, L H Li, Q B Huang, L N Zhang, M G Yin, X L Shang, X M Wang, F Tian, L X Liu, R Zhu, J Wu, Y Q Wu, C L Li, Y Zong, J T Hu, J Liu, Q Zhai, L J Deng, Y Y Deng, D W Liu
To establish the experts consensus on the management of delirium in critically ill patients. A special committee was set up by 15 experts from the Chinese Critical Hypothermia-Sedation Therapy Study Group. Each statement was assessed based on the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) principle. Then the Delphi method was adopted by 36 experts to reassess all the statements. (1) Delirium is not only a mental change, but also a clinical syndrome with multiple pathophysiological changes...
February 1, 2019: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
Yaakov Stern, Anna MacKay-Brandt, Seonjoo Lee, Paula McKinley, Kathleen McIntyre, Qolamreza Razlighi, Emil Agarunov, Matthew Bartels, Richard P Sloan
OBJECTIVE: To determine efficacy of aerobic exercise for cognitive function in younger healthy adults. METHODS: In a randomized, parallel-group, observer-masked, community-based clinical trial, 132 cognitively normal individuals aged 20-67 with below median aerobic capacity were randomly assigned to one of two 6-month, 4-times-weekly conditions: aerobic exercise and stretching/toning. Efficacy measures included aerobic capacity; cognitive function in several domains (executive function, episodic memory, processing speed, language, and attention), everyday function, body mass index (BMI), and cortical thickness...
January 30, 2019: Neurology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"