Raj Singh, Anisha Valluri, Eric J Lehrer, Yilin Cao, Rituraj Upadhyay, Daniel M Trifiletti, Simon S Lo, Kristin J Redmond, Arjun Sahgal, Quynh-Nhu Nguyen, Joshua D Palmer
There are limited data available on clinical outcomes after stereotactic body radiation therapy (SBRT) for nonspinal bone metastases. We performed a systematic review and meta-analysis to characterize local control (LC), overall survival (OS), pain response rates, and toxicity after SBRT. The primary outcomes were 1-year LC, incidence of acute and late grade 3 to 5 toxicities, and overall pain response rate at 3 months. The secondary outcome was 1-year OS. The Newcastle-Ottawa scale was used for assessment of study bias, with a median score of 5 for included studies (range, 4-8)...
January 12, 2024: International Journal of Radiation Oncology, Biology, Physics