Read by QxMD icon Read

Physical therapy and palliation

Wei-Qiang Wu, Song Peng, Zhi-Yuan Song, Shu Lin
Myocardial infarction (MI) remains one of the leading cause of mortality over the world. However, current treatments are more palliative than curative, which only stall the progression of the disease, but not reverse the disease. While stem cells or bioactive molecules therapy is promising, the limited survival and engraftment of bioactive agent due to a hostile environment is a bottleneck for MI treatment. In order to maximize the utility of stem cells and bioactive molecules for myocardial repair and regeneration, various types of biomaterials have been developed...
March 14, 2019: Drug Delivery and Translational Research
Wieslawa Piotrowska, Wojciech Leppert, Mikolaj Majkowicz
Aim: Comparison of analgesia, adverse effects, and quality of life (QoL) of cancer patients in the treatment of procedural pain induced by nursing procedures with the use of intravenous morphine, fentanyl nasal spray, and fentanyl buccal tablets. Methods: In adults with cancer with opioid tolerance and suffering procedural pain, intravenous morphine was used at an inpatient palliative medicine unit (20 patients) and fentanyl by intranasal (15 patients) and buccal routes (nine patients) at home...
2019: Cancer Management and Research
Larissa Nascimento Dos Santos, Luciana Castaneda, Suzana Sales de Aguiar, Luiz Claudio Santos Thuler, Rosalina Jorge Koifman, Anke Bergmann
OBJECTIVE:  To analyze the factors associated with health-related quality of life (HRQoL) in women with cervical cancer (CC) in a single center in Rio de Janeiro, state of Rio de Janeiro, Brazil. METHODS:  A cross-sectional study in women with a diagnosis of CC followed-up in the gynecology outpatient clinic of the Hospital do Câncer II (HCII, in the Portuguese acronym) of the Instituto Nacional de Câncer (INCA, in the Portuguese acronym). The data were collected from March to August 2015...
March 7, 2019: Revista Brasileira de Ginecologia e Obstetrícia
Laura Munson, Matthew F Funk, Terence A Perrault
Objective: The purpose of this report is to describe the evaluation and treatment of a patient initially presenting for chiropractic care of neck pain (NP) who was subsequently diagnosed with retropharyngeal calcific tendonitis (RCT). Clinical Features: A 53-year-old woman presented to a chiropractic office with severe idiopathic NP, loss of cervical mobility, and intermittent painful swallowing. She had a motor vehicle accident 6 months before with NP that resolved within a week without treatment...
December 2018: Journal of Chiropractic Medicine
Brandi M Crowe, Marieke Van Puymbroeck
In varying degrees, all women experience menopause, the condition of infertility due to altered reproductive hormones. The menopausal transition includes three phases-perimenopause, menopause, and postmenopause-each associated with physical and psychological symptoms that can negatively affect women's successful functioning in everyday life. In addition to conventional therapies intended to decrease the frequency and severity of symptoms, menopausal women are in need of coping mechanisms to assist in managing symptoms as they occur...
February 21, 2019: International Journal of Yoga Therapy
Christopher D Stephen, Kate T Brizzi, Marc A Bouffard, Pablo Gomery, Stacey L Sullivan, Julie Mello, Julie MacLean, Jeremy D Schmahmann
PURPOSE OF REVIEW: In this review, we present the multidisciplinary approach to the management of the many neurological, medical, social, and emotional issues facing patients with cerebellar ataxia. RECENT FINDINGS: Our holistic approach to treatment, developed over the past 25 years in the Massachusetts General Hospital Ataxia Unit, is centered on the compassionate care of the patient and their family, empowering them through engagement, and including the families as partners in the healing process...
February 21, 2019: Current Treatment Options in Neurology
Alison Haywood, Jacqueline Duc, Phillip Good, Sohil Khan, Kirsty Rickett, Petra Vayne-Bossert, Janet R Hardy
BACKGROUND: Dyspnoea is a common symptom in advanced cancer, with a prevalence of up to 70% among patients at end of life. The cause of dyspnoea is often multifactorial, and may cause considerable psychological distress and suffering. Dyspnoea is often undertreated and good symptom control is less frequently achieved in people with dyspnoea than in people with other symptoms of advanced cancer, such as pain and nausea. The exact mechanism of action of corticosteroids in managing dyspnoea is unclear, yet corticosteroids are commonly used in palliative care for a variety of non-specific indications, including pain, nausea, anorexia, fatigue and low mood, despite being associated with a wide range of adverse effects...
February 20, 2019: Cochrane Database of Systematic Reviews
Patricia Rico-Mena, Domingo Palacios-Ceña, Ricardo Martino-Alba, Lourdes Chocarro-Gonzalez, Javier Güeita-Rodríguez
BACKGROUND: Pediatric palliative care programs aim to improve the quality of life of children with severe life-threatening illnesses, and that of their families. Although rehabilitation and physical therapy provides a valuable tool for the control of symptoms, it has been poorly researched to date. Since the family represents such a fundamental support in these cases, it is important to deepen our understanding regarding the value of implementing rehabilitation programs from the parents' perspective...
February 15, 2019: European Journal of Physical and Rehabilitation Medicine
Melissa J Armstrong
PURPOSE OF REVIEW: This article describes current diagnostic criteria relating to the diagnosis of Lewy body dementia, highlights diagnostic controversies, and reviews treatment approaches. RECENT FINDINGS: Clinical diagnostic criteria for both Parkinson disease and dementia with Lewy bodies have been recently updated. These criteria result in overlap between individuals diagnosed with Parkinson disease and those with dementia with Lewy bodies. Although clinical features and symptomatic treatment overlap, differences remain in epidemiology and expected progression...
February 2019: Continuum: Lifelong Learning in Neurology
Tomofumi Miura, Yoshihisa Matsumoto, Takashi Kawaguchi, Yuto Masuda, Ayumi Okizaki, Hiroko Koga, Keita Tagami, Yuki Sumazaki Watanabe, Yuko Uehara, Takuhiro Yamaguchi, Tatsuya Morita
OBJECTIVES: Phase angle (PA) is a poor prognostic factor in patients with advanced cancer. This study aimed to identify possible correlations between PA and symptoms, quality of life, fluid retention, and laboratory data in cancer patients in palliative care settings. METHODS: Individuals who visited the outpatient clinic or were admitted to the palliative care unit were eligible. Patients with a performance status of 4 and/or those unable to complete questionnaires were excluded...
January 26, 2019: Nutrition and Cancer
Eric Freund, Kim Rouven Liedtke, Julia van der Linde, Hans-Robert Metelmann, Claus-Dieter Heidecke, Lars-Ivo Partecke, Sander Bekeschus
Metastatic colorectal cancer is the fourth most common cause of cancer death. Current options in palliation such as hyperthermic intraperitoneal chemotherapy (HIPEC) present severe side effects. Recent research efforts suggested the therapeutic use of oxidant-enriched liquid using cold physical plasma. To investigate a clinically accepted treatment regimen, we assessed the antitumor capacity of plasma-treated saline solution. In response to such liquid, CT26 murine colon cancer cells were readily oxidized and showed cell growth with subsequent apoptosis, cell cycle arrest, and upregulation of immunogenic cell death (ICD) markers in vitro...
January 24, 2019: Scientific Reports
Hiroki Sakurai, Mitsunori Miyashita, Kengo Imai, Shingo Miyamoto, Hiroyuki Otani, Ai Oishi, Yoshiyuki Kizawa, Eisuke Matsushima
Background: To improve palliative care practice, the need for patients-reported outcome measures is increasing globally. The Integrated Palliative care Outcome Scale (IPOS) is a streamlined outcome scale developed to comprehensively evaluate patients' distress. The goal of this study is to assess the reliability and validity of IPOS-Japanese version in cancer patients. Methods: This is a multicenter, cross-sectional observational study. We assessed the missing values, prevalence, test-retest reliability, criterion validity and known-group validity in Japanese adult cancer patients...
January 22, 2019: Japanese Journal of Clinical Oncology
Tito R Mendoza, Kenneth L Kehl, Oluwatosin Bamidele, Loretta A Williams, Qiuling Shi, Charles S Cleeland, George Simon
BACKGROUND: Patients with newly diagnosed lung cancer who have not yet begun treatment may already be experiencing major symptoms produced by their disease. Understanding the symptomatic effects of cancer treatment requires knowledge of pretreatment symptoms (both severity and interference with daily activities). We assessed pretreatment symptom severity, interference, and quality of life (QOL) in treatment-naïve patients with lung cancer and report factors that correlated with symptom severity...
January 19, 2019: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
R de Las Peñas, M Majem, J Perez-Altozano, J A Virizuela, E Cancer, P Diz, O Donnay, A Hurtado, P Jimenez-Fonseca, M J Ocon
Nutritional deficiency is a common medical problem that affects 15-40% of cancer patients. It negatively impacts their quality of life and can compromise treatment completion. Oncological therapies, such as surgery, radiation therapy, and drug therapies are improving survival rates. However, all these treatments can play a role in the development of malnutrition and/or metabolic alterations in cancer patients, induced by the tumor or by its treatment. Nutritional assessment of cancer patients is necessary at the time of diagnosis and throughout treatment, so as to detect nutritional deficiencies...
January 2019: Clinical & Translational Oncology
Hannah Major-Monfried, Linda V DeCherrie, Ania Wajnberg, Meng Zhang, Amy S Kelley, Katherine A Ornstein
BACKGROUND: Many older adults are homebound due to chronic illness and suffer from significant symptoms, including pain. Home-based primary and palliative care (HBPC), which provides interdisciplinary medical and psychosocial care for this population, has been shown to significantly reduce symptom burden. However, little is known about how pain is managed in the homebound. OBJECTIVE: This article describes pain management for chronically, ill homebound adults in a model, urban HBPC program...
April 2019: American Journal of Hospice & Palliative Care
Ghaleb Khirfan, Adriano R Tonelli, Jennifer Ramsey, Sandeep Sahay
Pulmonary arterial hypertension (PAH) is a condition characterised by increased pulmonary vascular resistance which can lead to right heart failure and premature death. It imposes a significant burden on patients' lives, affecting their physical, emotional and social wellbeing. Pharmacological therapies are the mainstay of treatment; while they are not curative, they can alleviate patient suffering, improve quality of life and delay disease progression. Despite these therapies, disease progresses in a significant number of patients, who are faced with the debilitating symptoms of PAH and treatment adverse effects...
December 31, 2018: European Respiratory Review: An Official Journal of the European Respiratory Society
Mateusz Gajda, Jakub Kenig
BACKGROUND: The older population is very heterogeneous with regard to the co-morbidityand the physical reserve. This can result in unacceptably high postoperative complications rates. Therefore, the aim of the study was to review the literature regarding the outcomes of older patients treated for pancreatic cancer, including the usage of minimal invasive techniques. METHODOLOGY: A review of the literature was carried out including studies on pancreatic cancer in older patients published between 2011 and 2016...
2018: Folia Medica Cracoviensia
Robert Meyer, Susanne Spittel, Laura Steinfurth, Andreas Funke, Dagmar Kettemann, Christoph Münch, Thomas Meyer, André Maier
BACKGROUND: Physical therapy is an essential component of multidisciplinary treatment in amyotrophic lateral sclerosis (ALS). However, the meaning of physical therapy beside preservation of muscular strength and functional maintenance is not fully understood. OBJECTIVE: The purpose of this study was to examine patients' perception of physical therapy during symptom progression using an internet assessment approach. METHODS: A prospective, longitudinal, observational study was performed...
November 12, 2018: JMIR Rehabilitation and Assistive Technologies
Yinyan Gao, Yanping Wei, Wenjiao Yang, Lili Jiang, Xiuxia Li, Jie Ding, Guowu Ding
CONTEXT: The quality of death has increasingly raised concern because of the physical and psychological suffering of patients with advanced disease. Music therapy has been widely used in palliative care; however, its physical and mental effectiveness remains unclear. OBJECTIVE: To assess the effectiveness of music therapy during palliative care in improving physiology and psychology outcomes. METHODS: Randomized controlled trials evaluating music therapy for terminally ill patients were searched and included from inception up to April 25, 2018...
October 30, 2018: Journal of Pain and Symptom Management
T Kirchner, S Marquardt, T Werncke, M M Kirstein, T Brunkhorst, F Wacker, A Vogel, Thomas Rodt
PURPOSE: The purpose of this study was to compare quality of life (QoL) after two different transarterial therapies [transarterial chemoembolization (TACE) and transarterial radioembolization (TARE)] for patients with unresectable hepatocellular carcinoma (HCC) to assess tumor therapy in palliative situation additional to traditional aims like survival or image response. MATERIAL AND METHODS: QoL was evaluated with two validated questionnaires (EORTC QLQ-30 and EORTC HCC18) before and 14d after treatment in 94 initial therapies (TACE n = 67; TARE n = 27)...
October 11, 2018: Abdominal Radiology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"