Geza Nagy, Zsolt Ronai, Aniko Somogyi, Maria Sasvari-Szekely, Omar Abdul Rahman, Attila Mate, Timea Varga, Zsofia Nemoda
AIMS: Both diabetes mellitus and major depression are public health concerns, and the co-occurrence of these illnesses is highly frequent. Acting as a potential risk factor, hyperglycemia might facilitate the manifestation of depression in patients genetically predisposed to affective disorders. In the present study, candidate polymorphisms of the serotonin transporter, the tryptophan hydroxylase 2 (TPH2) genes, as well as of the brain-derived neurotrophic factor BDNF, and the P2RX7 purinergic receptor genes were analyzed in Hungarian diabetic population...
December 12, 2008: Progress in Neuro-psychopharmacology & Biological Psychiatry