Wael El-Matary, Matthew W Carroll, Colette Deslandres, Anne M Griffiths, M Ellen Kuenzig, David R Mack, Eytan Wine, Jake Weinstein, Rose Geist, Tal Davis, Justin Chan, Rabia Khan, Priscilla Matthews, Gilaad G Kaplan, Joseph W Windsor, Charles N Bernstein, Alain Bitton, Stephanie Coward, Jennifer L Jones, Kate Lee, Sanjay K Murthy, Laura E Targownik, Juan-Nicolás Peña-Sánchez, Noelle Rohatinsky, Sara Ghandeharian, James H B Im, Quinn Goddard, Julia Gorospe, Jules Verdugo, Samantha A Morin, Taylor Morganstein, Lisa Banning, Eric I Benchimol
Rates of inflammatory bowel disease (IBD) in Canadian children and adolescents are among the highest in the world, and the incidence is rising most rapidly in children under five years of age. These young children may have either a typical form of IBD with multi-factorial aetiology, or they may have a monogenic form. Despite the growing number of children in Canada living with this important chronic disease, there are few available medical therapies approved by Health Canada due to the omission of children from most clinical trials of newly developed biologics...
September 2023: Journal of the Canadian Association of Gastroenterology