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Chickenpox bullous

Annalan Mathew Dwight Navaratnam, Nan Ma, Maria Farrukh, Aza Abdulla
A 97-year-old woman presented with 4-day history of vesicular rash, initially at the feet but then spread up to the thighs bilaterally, abdomen and trunk. The initial differentials included bullous pemphigus and cellulitis by the emergency department. She was then managed as bullous pemphigus by the acute medical team and started on high-dose steroids, with no other differentials considered. When her care was taken over by the general medical team, varicella zoster virus (VZV) infection was suspected. After confirmation by the dermatology team regarding the clinical diagnosis and the positive VZV DNA swabs, she was started on acyclovir...
December 22, 2017: BMJ Case Reports
Nitin Verma, Charles Pickles, Muhammad Amjad Khan
Linear IgA disease of childhood (LAD) also known as chronic bullous disease of childhood is an autoimmune disease with IgA deposition at the basement membrane zone leading to a vesiculobullous rash. It has a clinical appearance which frequently is described as resembling "strings of pearls" or rosette-like. Diagnosis is usually clinical but sometimes biopsy is required. Dapsone is widely considered to be the first line therapy in the treatment of LAD. A 5-year-old girl presented with 4-day history of a widespread painful rash and pyrexia...
2016: Case Reports in Pediatrics
T S Mohanarao, Gummalla Ajay Kumar, Kavya Chennamsetty, T Priyadarshini
Lichen planus pemphigoides (LPP) is a rare autoimmune bullous disorder that is rarer in children characterized by bullae on lichen planus like papules and the normal looking skin. Clinical, histopathological and direct immunoflourescence evaluation is important for the diagnosis of this entity. We report a case of LPP in a 5-year-old girl child probably triggered by an episode of preceding varicella. Diagnosis was confirmed by histopathology and immunofluorescence examination. Histological findings were typical of lichen planus from the biopsy taken from a violaceous to erythematous papule and characteristic of bullous pemphigoid in the biopsy taken from a bullous lesion with evidence of immunoglobulin G and C3 deposition along the basement membrane zone on direct immunofluorescence...
December 2014: Indian Dermatology Online Journal
Valeria Brazzelli, Vincenzo Grasso, Grazia Bossi, Giovanni Borroni
We present a case of infantile bullous pemphigoid (BP) triggered by primary infection with varicella zoster virus and we analyze the correlation between autoantibody levels and disease activity. With this report we suggest that serum autoantibody titers may not necessarily mirror the clinical course of the disease or represent a helpful tool in guiding therapeutic decisions in infantile BP.
November 2014: Pediatric Dermatology
Hiroshi Yamaguchi, Etsuko Sekimoto, Atsuhisa Shirakami, Hironobu Shibata, Shuji Ozaki, Toshio Shigekiyo, Toshinori Noda, Takanori Shikiji, Kazuya Kanda, Takanori Hirose, Tetsuhiro Matsuzawa, Tohru Gonoi
We herein report the case of a 77-year-old man admitted for an acute cutaneous infection and persistent fever. A physical examination revealed systemic small blisters and scrotal swelling. He was suspected of having complications from chickenpox or bullous impetigo as the initial diagnosis. Nocardia was detected on an aspiration biopsy of the small blisters and the surgically removed testis at a later date. Testicular nocardiosis is a rare condition; however, we should consider nocardiosis in the differential diagnosis because delay in providing treatment may worsen a patient's general condition...
2013: Internal Medicine
Ana Maria Abreu Velez, Bruce R Smoller, Weiqing Gao, Hans E Grossniklaus, Zhe Jiao, Luis F Arias, Samuel C Dudley, Michael S Howard
BACKGROUND: Herpes virus infections are well known infectious complications of pemphigus and bullous pemphigoid. We describe pathologic findings utilizing autopsy tissue from several organs from a patient affected by a new variant of endemic pemphigus in El Bagre, Colombia, South America. CASE REPORT: We describe a patient by a new variant of endemic pemphigus foliaceus from El Bagre that was receiving high-dosage immunosuppressants when hospitalized and died suddenly following contact with a second patient affected by chicken pox...
July 2012: International Journal of Dermatology
Turna İlknur, Sevgi Akarsu, Soner Uzun, Erdener Özer, Emel Fetil
Lichen planus pemphigoides (LPP) is a rare and controversial disease. It is characterized clinically by tense bullae arising both on lichen planus papules and on uninvolved skin, histologically by the demonstration of subepidermal bullae and by linear deposits of immunoglobulin G and C3 along the basement membrane zone on immunofluorescence of peribullous skin. Some authors consider LPP as the combination of lichen planus and bullous pemphigoid. Others think that it most likely encompasses a heterogeneous group of subepidermal autoimmune blistering disorders occurring in association with lichen planus...
July 2011: Journal of Dermatology
Mazen Kurban, Zenus Saleh, Myrna El Shareef, Abdul-Ghani Kibbi, Samer Ghosn
No abstract text is available yet for this article.
September 2008: International Journal of Dermatology
No abstract text is available yet for this article.
January 1963: Clinical Pediatrics
No abstract text is available yet for this article.
February 1960: Revue de Pathologie Générale et de Physiologie Clinique
No abstract text is available yet for this article.
February 1, 1958: British Medical Journal (1857-1980)
R Ahkami, I Thomas
Linear IgA bullous dermatosis (LABD) is characterized by linear deposits of IgA at the basement membrane zone. Most cases are idiopathic, but medications, infections, autoimmune disorders, and malignancies have been documented as potential inducers. We report a case where both vancomycin and varicella-zoster infection were present as triggers.
May 2001: Cutis; Cutaneous Medicine for the Practitioner
H M Feder, K E Pond
We report two pediatric patients with recalcitrant staphylococcal infections whose infections resolved when rifampin was added to standard antistaphylococcal therapy. One patient had a post-varicella staphylococcal ulcerative lesion and did not respond to cephalexin alone but did respond when rifampin was added. A second patient had staphylococcal bullous impetigo and did not respond to dicloxacillin or cephalexin but did respond when rifampin was added to the cephalexin. If a patient fails to respond to traditional antistaphylococcal therapy, the addition of rifampin may be beneficial...
April 1996: Clinical Pediatrics
A C Choy, P R Yarnold, J E Brown, G T Kayaloglou, P A Greenberger, R Patterson
Erythema Multiforme is an acute, self-limited inflammatory cutaneous disorder characterized by distinctive target lesions. Stevens-Johnson syndrome (SJS) is defined as severe erythema multiforme with mucosal involvement, visceral involvement, or both. Both diseases are part of a continuum of immunologically mediated mucocutaneous diseases at various grades of severity. Viral infections are known triggers of these skin disorders. We report the success of a management strategy of acyclovir and prednisone for herpes simplex virus-associated erythema multiforme...
July 1995: Allergy Proceedings: the Official Journal of Regional and State Allergy Societies
G M White, P Broska
No abstract text is available yet for this article.
January 1994: Archives of Dermatology
J Fäh, J Pavlovic, G Burg
The human MxA protein can be detected in the cytoplasm of IFN-alpha/beta-treated cells, whereas other cytokines, including IFN-gamma, are poor inducers. Because IFN-alpha/beta is predominantly synthesized in response to viral infections, MxA protein should be detectable in virally infected tissue. Biopsy specimens (n = 64) of 12 different dermatoses were therefore screened with an MxA-specific monoclonal antibody on formalin-fixed, paraffin-embedded and microwave-treated tissue sections. As expected, high amounts of MxA protein were found in acute viral skin lesions (chickenpox, Herpes zoster, and Herpes labialis)...
January 1995: Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society
R A Schwartz, M C Jordan, D J Rubenstein
We report a 70-year-old man with the bullous variant of chickenpox. Physicians should be aware of this uncommon manifestation of this common disease, which may clinically suggest other bullous disorders such as pemphigus and bullous pemphigoid. A 24-year-old hospital worker developed typical chickenpox 2 weeks after the first patient's onset of bullous chickenpox.
August 1983: Journal of the American Academy of Dermatology
H M Frey, S P Steinberg, A A Gershon
A simple, accurate, and rapid method for laboratory diagnosis of varicella-zoster virus (VZV) infections using countercurrent immunoelectrophoresis (CIE) is described. CIE uses zoster convalescent-phase serum to detect VZV antigen in vesticular fluid. Eighty-six patients were studied, 58 with VZV infections and 28 with vesicular or bullous rashes due to causes other than VZV infection. All patients with documented VZV infection had positive CIE tests for VZV, and the controls were uniformly negative. VZV antigen could be detected up to 15 (varicella) or 16 (zoster) days after the onset of rash...
February 1981: Journal of Infectious Diseases
M Ryba
No abstract text is available yet for this article.
April 1966: Ceskoslovenská Pediatrie
M Lemańczyk, Z Jaros-Kijewska
No abstract text is available yet for this article.
January 15, 1968: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
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