keyword
https://read.qxmd.com/read/38635552/predicting-ruminal-degradability-and-chemical-composition-of-corn-silage-using-near-infrared-spectroscopy-and-multivariate-regression
#1
JOURNAL ARTICLE
Pauliane Pucetti, Sebastião de Campos Valadares Filho, Jussara Valente Roque, Julia Travassos da Silva, Kellen Ribeiro de Oliveira, Flavia Adriane Sales Silva, Wilson Junior Cardoso, Fabyano Fonseca E Silva, Kendall Carl Swanson
The aim of this study was to develop and validate regression models to predict the chemical composition and ruminal degradation parameters of corn silage by near-infrared spectroscopy (NIR). Ninety-four samples were used to develop and validate the models to predict corn silage composition. A subset of 23 samples was used to develop and validate models to predict ruminal degradation parameters of corn silage. Wet chemistry methods were used to determine the composition values and ruminal degradation parameters of the corn silage samples...
2024: PloS One
https://read.qxmd.com/read/38635042/purification-of-dna-nanoparticles-using-photocleavable-biotin-tethers
#2
JOURNAL ARTICLE
Heather R Everson, Kayla Neyra, Dylan V Scarton, Soumya Chandrasekhar, Christopher M Green, Thorsten-Lars Schmidt, Igor L Medintz, Remi Veneziano, Divita Mathur
The number of applications of self-assembled deoxyribonucleic acid (DNA) origami nanoparticles (DNA NPs) has increased drastically, following the development of a variety of single-stranded template DNA (ssDNA) that can serve as the scaffold strand. In addition to viral genomes, such as M13 bacteriophage and lambda DNAs, enzymatically produced ssDNA from various template sources is rapidly gaining traction and being applied as the scaffold for DNA NP preparation. However, separating fully formed DNA NPs that have custom scaffolds from crude assembly mixes is often a multistep process of first separating the ssDNA scaffold from its enzymatic amplification process and then isolating the assembled DNA NPs from excess precursor strands...
April 18, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38634615/calcified-cartilage-guided-identification-of-osteogenic-molecules-and-geometries
#3
JOURNAL ARTICLE
Katsuhiro Kawaai, Yukiko Kuroda, Koichi Matsuo
Calcified cartilage digested by chondroclasts provides an excellent scaffold to initiate bone formation. We analyzed bioactive proteins and microarchitecture of calcified cartilage either separately or in combination and evaluated biomimetic osteogenic culture conditions of surface-coated micropatterning. To do so, we prepared a crude extract from porcine femoral growth plates, which enhanced in vitro mineralization when coated on flat-bottom culture dishes, and identified four candidate proteins by fractionation and mass spectrometry...
April 18, 2024: ACS Biomaterials Science & Engineering
https://read.qxmd.com/read/38633965/anti-inflammatory-properties-of-strontium-oxide-nanoparticles-synthesized-from-suaeda-monoica-saltmarsh
#4
JOURNAL ARTICLE
Pranam Sinha, Priya Boopathi, Vasugi Suresh, Sivaperumal Pitchiah
Background Currently, nanotechnology is a rapidly advancing field of research. Because of their nanoscale dimensions, nanoparticles (NPs) find application in a wide range of industries, including engineering and medicine. The leaves of Suaeda monoica have anti-inflammatory qualities. The purpose of this study was to create SrO NPs isolated from the leaves of  S. monoica  aqueous extract and to evaluate their anti-inflammatory efficacy. The S .  monoica  saltmarsh, commonly known as South-Indian Seepweed, is a mangrove-associated plant and has been used as traditional medicine for decades with multifunctional biological activity...
March 2024: Curēus
https://read.qxmd.com/read/38633951/unraveling-a-rare-case-of-epidural-extramedullary-hematopoiesis-in-a-patient-with-transfusion-dependent-beta-thalassemia-presenting-with-spinal-cord-compression
#5
Raed Masalma, Thabet Zidan, Khalil M Abualhumos, Dalia Hamayel, Ziad Abukhalil, Ahmed T Ghanem, Adnan Mousa, Maroun Helou, Wesam Tamimi, Mahdi Al-Sayed Ahmad
Thalassemia is known to induce extramedullary hematopoiesis (EMH), which is a compensatory mechanism in which the body forms blood cells outside the bone marrow. While EMH typically affects organs such as the spleen and liver, there are rare instances where it leads to spinal cord compression (SCC) in the epidural space. A 31-year-old male patient with transfusion-dependent beta thalassemia presented with numbness and bilateral limb weakness due to EMH. Neurological examination revealed increased tone in both legs, reduced power, loss of crude touch and pain sensation, and increased deep tendon reflexes...
March 2024: Curēus
https://read.qxmd.com/read/38633889/phytochemical-characterization-by-gc-ms-and-in-vitro-evaluation-of-antiproliferative-and-antimigratory-studies-of-leucas-aspera-leaf-extracts-on-mda-mb-231-cell-line
#6
JOURNAL ARTICLE
Mahaboob Begum S M Fazeela, Megasri Sankarram
Breast cancer is the most recurrently identified and one of women's prominent causes of death. Currently, researchers have turned their focus on natural chemicals from synthetic chemicals due to their environmental, economic, and health benefits. Considering this, the medicinal plant Leucas aspera was chosen for the current study. The aim of this study was to isolate and characterize secondary metabolites from L. aspera and determine the antiproliferative and antimigratory activities in the MDA-MB-231 cell line under in vitro conditions...
2024: Biotechnologia
https://read.qxmd.com/read/38633737/comparative-evaluation-of-amino-acid-profiles-fatty-acid-compositions-and-nutritional-value-of-two-varieties-of-head-water-porphyra-yezoensis-jianghaida-no-1-and-sutong-no-1
#7
JOURNAL ARTICLE
Bin Guan, Yuyan Sun, Xuxiao Liu, Chongyu Zhong, Desheng Li, Xin Shan, Xingxing Hui, Chaofa Lu, Yujia Huo, Runkai Sun, Min Wei, Wei Zheng
Comparative nutritional analysis of Porphyra yezoensis strains "Jianghai No. 1" and "Sutong No.1" revealed significant differences in crude protein, crude fat, crude fiber, crude ash, and total sugar. Both strains contained 16 amino acids, with alanine as the highest and histidine the lowest content. Methionine was determined to be the first limiting amino acid for both strains in both amino acid score and chemical score assessment. They also featured 24 fatty acids, differing notably in four saturated fatty acids and five unsaturated fatty acids...
June 30, 2024: Food chemistry: X
https://read.qxmd.com/read/38633612/the-traditional-uses-pharmacology-and-phytochemistry-of-peucedanum-praeruptorum-dunn
#8
REVIEW
Qiongxiao Wang, Qingmei Sun, Qinger Huang, Luping Qin, Bo Zhu
Bai Hua Qian Hu (Qianhu; Peucedanum praeruptorum Dunn) is a classical medicinal plant traditionally prescribed for respiratory ailments, including cough, pulmonary hypertension, and asthma. In this review, we summarize the research progress of the toxicology, pharmacokinetics, pharmacology, phytochemistry, botany, quality control, and traditional uses of P. praeruptorum in order to support future investigations into the scientific and therapeutic promise of this important medicinal plant. Information pertaining to P...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38633504/development-of-a-membrane-disruption-assay-using-phospholipid-vesicles-as-a-proxy-for-the-detection-of-cellular-membrane-degradation
#9
JOURNAL ARTICLE
Mátyás A Bittenbinder, Eric Wachtel, Daniel Da Costa Pereira, Julien Slagboom, Nicholas R Casewell, Paul Jennings, Jeroen Kool, Freek J Vonk
Snakebite envenoming is a global health issue that affects millions of people worldwide, and that causes morbidity rates surpassing 450,000 individuals annually. Patients suffering from snakebite morbidities may experience permanent disabilities such as pain, blindness and amputations. The (local) tissue damage that causes these life-long morbidities is the result of cell- and tissue-damaging toxins present in the venoms. These compounds belong to a variety of toxin classes and may affect cells in various ways, for example, by affecting the cell membrane...
June 2024: Toxicon: X
https://read.qxmd.com/read/38632578/sex-related-inequalities-in-crude-and-age-standardized-suicide-rates-trends-in-ghana-from-2000-to-2019
#10
JOURNAL ARTICLE
Faustina Adoboi, Aliu Mohammed, Precious Adade Duodu, Richard Gyan Aboagye, Abdul-Aziz Seidu, Florence Gyembuzie Wongnaah, Bright Opoku Ahinkorah
BACKGROUND: Suicide represents a major public health concern, affecting a significant portion of individuals. However, there remains a gap in understanding the age and sex disparities in the occurrence of suicide. Therefore, this study aimed to investigate the sex-related inequalities in suicide rates in Ghana from 2000 to 2019. METHODS: We utilized data from the WHO Health Equity Assessment Toolkit (HEAT) online software. We analysed sex differences in both crude and age-standardized suicide rates in Ghana spanning from 2000 to 2019...
April 17, 2024: BMC Public Health
https://read.qxmd.com/read/38632269/gamma-radiation-induced-grafting-of-poly-butyl-acrylate-onto-ethylene-vinyl-acetate-copolymer-for-improved-crude-oil-flowability
#11
JOURNAL ARTICLE
Ahmed Siddiq, Mohamed M Ghobashy, Abu-Bakr A A M El-Adasy, Ashraf M Ashmawy
Ethylene vinyl acetate (EVA) copolymers are widely employed as pour point depressants to enhance the flow properties of crude oil. However, EVA copolymers have limitations that necessitate their development. This work investigated the modification of EVA via gamma radiation-induced grafting of butyl acrylate (BuA) monomers and the evaluation of grafted EVA as a pour point depressant for crude oil. The successful grafting of poly(butyl acrylate) p(BuA) onto EVA was verified through grafting parameters, FTIR spectroscopy, and 1 H NMR spectroscopy...
April 17, 2024: Scientific Reports
https://read.qxmd.com/read/38631396/phytochemical-evaluation-embryotoxic-and-teratogenic-effects-of-buwakan-decalobanthus-peltatus-l-a-r-sim%C3%A3%C2%B5es-staples-leaf-extracts-on-duck-embryo
#12
JOURNAL ARTICLE
Merrah Joy Blaya Subebe, Josephine C Ogaro, Melanie L Dayon, Muhmin Michael E Manting, Aki Murashima, Akiko Omori, Jaime Q Guihawan, Mylene M Uy, Ahmad Reza F Mazahery, Mylah Villacorte-Tabelin
Decalobanthus peltatus is a woody vine that is commonly utilized in traditional Southeast Asian medicinal preparations. Despite the documented therapeutic uses of D. peltatus, there is hardly any information regarding its toxic effects on its consumers. In this study, crude leaf extracts (aqueous, methanol, ethyl acetate, and hexane) from D. peltatus were prepared and evaluated for their embryotoxicity and teratogenic effects. Phytochemical screening of bioactive compounds from the plants showed the presence of alkaloids, flavonoids, saponins, steroids, and tannins...
March 2024: Environmental analysis, health and toxicology
https://read.qxmd.com/read/38631310/estimating-the-prevalence-of-cerebral-palsy-in-a-semi-urban-city-in-benin-a-door-to-door-community-based-study
#13
JOURNAL ARTICLE
Emmanuel Segnon Sogbossi, Adjoua Baba-Tadja, Emilienne Nouatin, Mendinatou Agbetou, Thierry Adoukonou, Oyéné Kossi
INTRODUCTION: Cerebral palsy (CP) is the most common cause of pediatric motor disability. While epidemiological data are widespread in high-income countries, corresponding data in low-income countries in Sub-Saharan Africa are still rare. This study aimed to estimate the prevalence of CP in Northern Benin, a French-speaking low-income country in Sub-Saharan Africa. METHODS: This study was a community-based door-to-door study involving children younger than 18 years old, in Parakou, a semi-urban city in Benin...
April 17, 2024: Neuroepidemiology
https://read.qxmd.com/read/38631278/factors-associated-with-prolonged-qtc-interval-in-iranian-population-mashad-cohort-study
#14
JOURNAL ARTICLE
Toktam Sahranavard, Sara Saffar Soflaei, Rasoul Alimi, Ghazaleh Pourali, Mohamad Nasrabadi, Asal Yadollahi, Shima Sharifi, Hedieh Alimi, Bahram Shahri, AmirAli Moodi Ghalibaf, Sepehr Metanat, Gordon A Ferns, Mohsen Moohebati, Majid Ghayour-Mobarhan
AIM: QTc interval prolongation is a growing global issue which can cause torsades de pointes, a potentially fatal arrhythmia. We aimed to identify risk factors for prolonged QT interval in men and women. METHODS: The Mashhad stroke and heart atherosclerotic disorder (MASHAD) cohort study collected electrocardiogram interval data. QT was corrected for heart rate using the Bazett's formula. Ordinal logistic regression with crude (univariable) and adjusted (multivariate) association analyses in the form of odds ratio and corresponding 95% confidence interval (CI) were used to identify the factors associated with QTc prolongation...
April 16, 2024: Journal of Electrocardiology
https://read.qxmd.com/read/38630428/effect-of-theophylline-on-stent-related-symptoms-in-patients-undergoing-double-j-ureteral-stent-insertion-a-randomized-controlled-trial
#15
JOURNAL ARTICLE
Alireza Pakdel, Abdolreza Mohammadi, Hossein Chivaee, Amirreza Shamshirgaran, Hossein Amirzargar, Reza Mohammadi Farsani, Fardin Asgari, Alireza Khajavi, Seyed Mohammad Kazem Aghamir
PURPOSE: To investigate the effect of oral theophylline on stent-related syndrome (SRS) after Double-J insertion. BACKGROUND: Double-J stent is widely using in many urological procedures. Infection, hematuria, and discomfort are some of common complication after stenting. Theophylline is a dimethylated xanthine that inhibits phosphodiesterase and blocks adenosine receptors. To relaxing effect of theophylline on smooth muscles and its effects on the urinary system, it seems it could reduce complications after inserting Double-J stent especially ureteral stent syndrome...
April 17, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38630319/linking-the-protease-activity-to-the-nematicidal-action-of-edible-mushroom
#16
JOURNAL ARTICLE
Adriane Toledo da Silva, Debora Castro de Souza, Stefany Amorim de Souza, Jhennifer Cristina de Souza Alves, Eustáquio Souza Dias, Liliana Aguilar-Marcelino, Filippe Elias de Freitas Soares
Biological control using edible mushrooms as natural enemies is a sustainable alternative for pest management. Despite the well-established literature on toxins and secondary metabolites produced by these fungi in the biochemical control of nematodes, the nematicidal activity of proteases from different Pleurotus species is yet to be investigated. Therefore, this study aimed to correlate protease to the nematicidal activity of different mushrooms, Pleurotus sp., P. ostreatus (SB), P. ostreatus (Pearl), and P...
April 17, 2024: World Journal of Microbiology & Biotechnology
https://read.qxmd.com/read/38629636/low-valent-tungsten-catalysis-enables-hydroboration-of-esters-and-nitriles
#17
JOURNAL ARTICLE
Heng Song, Yuting Xiao, Jingjing Wei, Yuzan Liu, Liqing Yang, Pengtao Bai, Fu Yang, Kai Yu, Chen Xu, Xingwei Cai
In the research presented herein, low-valent-tungsten-catalyzed hydroboration of esters and nitriles was investigated. Aromatic and aliphatic substrates were smoothly reduced to corresponding alcohol derivatives and N , N -diborylamines in the presence of W(CO)4 (NCMe)2 . Valuable derivatives were conveniently accessed by introducing a further functionalization process to crude hydroboration mixtures in one pot.
April 17, 2024: Chemical Communications: Chem Comm
https://read.qxmd.com/read/38629485/regional-practice-variation-in-hysterectomy-and-the-implementation-of-less-invasive-surgical-procedures-a-register-based-study-in-the-netherlands
#18
JOURNAL ARTICLE
Maarten D H Vink, France R M Portrait, Wouter J K Hehenkamp, Tim van Wezep, Xander Koolman, Marlies Y Bongers, Eric J E van der Hijden
INTRODUCTION: Many women experience bleeding disorders that may have an anatomical or unexplained origin. Although hysterectomy is the most definitive and common treatment, it is highly invasive and resource-intensive. Less invasive therapies are therefore advised before hysterectomy for women with fibroids or bleeding disorders. This study has two aims related to treating bleeding disorders and uterine fibroids in the Netherlands: (1) to evaluate the regional variations in prevalence and surgical approaches; and (2) to assess the associations between regional rates of hysterectomies and less invasive surgical techniques to analyze whether hysterectomy can be replaced in routine practice...
April 17, 2024: Acta Obstetricia et Gynecologica Scandinavica
https://read.qxmd.com/read/38628689/comparison-study-between-single-enzyme-and-multienzyme-complex-in-distiller-s-dred-grains-with-soluble-supplemented-diet-in-broiler-chicken
#19
JOURNAL ARTICLE
Min-Jin Kwak, Dong-Jin Ha, Min Young Park, Ju Young Eor, Kwang-Youn Whang, Younghoon Kim
Upregulation of the nutritional value of feed is the major target of various studies in the livestock industry, and dietary enzyme supplementation could aid in digesting the nondegrading nutrients of grains in feed ingredients. Dried distillers' grains with solubles (DDGS) is a byproduct of the fermentation process in the beverage industry and can be used as a large supply source of fiber in feed. Therefore, we conducted an experiment with male broiler chickens to investigate the effect of various types of enzymes on DDGS and compare the efficacy of single enzyme and multienzyme complexes on growth performance and gut environments in broiler chickens...
March 2024: Journal of Animal Science and Technology
https://read.qxmd.com/read/38628688/prediction-of-apparent-total-tract-digestion-of-crude-protein-in-adult-dogs
#20
JOURNAL ARTICLE
Kangmin Seo, Hyun-Woo Cho, Min Young Lee, Chan Ho Kim, Ki Hyun Kim, Ju Lan Chun
To predict the apparent total tract digestibility (ATTD) of crude protein (CP) in dogs we developed an in vitro system using an in vitro digestion method and a statistical analysis. The experimental diets used chicken meat powder as the protein source, with CP levels of 20% (22.01%, analyzed CP value as dry-based), 30% (31.35%, analyzed CP value as dry-based), and 40% (41.34%, analyzed CP value as dry-based). To simulate in vivo digestive processes a static in vitro digestion was performed in two steps; stomach and small intestine...
March 2024: Journal of Animal Science and Technology
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