keyword
https://read.qxmd.com/read/38535643/exploring-borate-modified-calcium-phosphate-ceramics-antimicrobial-potential-and-cytocompatibility-assessment
#1
JOURNAL ARTICLE
Inna V Fadeeva, Katia Barbaro, Annalisa Altigeri, Anna A Forysenkova, Marat R Gafurov, Georgy V Mamin, Alexander V Knot'ko, Viktoriya G Yankova, Anna A Zhukova, Fabrizio Russo, Julietta V Rau
Addressing periprosthetic infections, which present significant healing challenges that often require revision surgeries, necessitates the development of novel antibacterial materials and implants. Current research focuses on creating materials that hinder bacterial adhesion, colonization, and proliferation in surrounding tissues. Boron (B)-containing compounds are known for their antibacterial properties and potential in bone metabolism for regenerative medicine. In this study, we synthesized B-containing tricalcium phosphate (0...
March 9, 2024: Nanomaterials
https://read.qxmd.com/read/38534633/early-outcome-differences-between-acute-and-chronic-periprosthetic-joint-infections-a-retrospective-single-center-study
#2
JOURNAL ARTICLE
Yasmin Youssef, Elisabeth Roschke, Nadine Dietze, Anna-Judith Dahse, Iris F Chaberny, Donald Ranft, Christina Pempe, Szymon Goralski, Mohamed Ghanem, Regine Kluge, Christoph Lübbert, Arne C Rodloff, Andreas Roth
Periprosthetic joint infections (PJI) are serious complications after arthroplasty, associated with high morbidity, mortality, and complex treatment processes. The outcomes of different PJI entities are largely unknown. The aim of this study was to access the early outcomes of different PJI entities. A retrospective, single-center study was conducted. The characteristics and outcomes of patients with PJI treated between 2018 and 2019 were evaluated 12 months after the completion of treatment. Primary endpoints were mortality, relapse free survival (RFS) and postoperative complications (kidney failure, sepsis, admission to ICU)...
February 20, 2024: Antibiotics
https://read.qxmd.com/read/38533423/delayed-diagnosis-of-mycobacteri-um-bovis-bacillus-calmette-gu%C3%A3-rin-periprosthetic-joint-infection-following-total-knee-arthroplasty
#3
Christopher E Pelt, Salika Shakir, Michael J Cahill, Jakrapun Pupaibool, Barbara C Cahill
Periprosthetic joint infection (PJI) can present challenges in diagnosis and treatment, particularly in the setting of atypical causative organisms such as fungi and mycobacteria. Herein, we present a case and provide a review of the diagnosis and treatment of an unusual PJI caused by bacillus Calmette-Guérin, administered during the treatment of bladder cancer 3 years prior to total knee arthroplasty and subsequent PJI. Although the patient's history of bladder cancer was known, neither his Bacillus Calmette-Guérin treatment nor its potential for distant site spread that could lead to PJI were appreciated, leading to a prolonged diagnostic evaluation and treatment course...
June 2024: Arthroplasty Today
https://read.qxmd.com/read/38532126/utilizing-an-antibiotic-eluting-articulated-cemented-spacer-in-the-two-stage-management-of-infected-total-hip-arthroplasty-a-technical-note
#4
JOURNAL ARTICLE
Aditya L Kekatpure, Aashay L Kekatpure, Jae Youn Yoon, Pil Whan Yoon, Jun-Ki Moon
Two-stage revision is generally preferred to eradicate chronic periprosthetic infections after total hip arthroplasty (THA) because of its good infection control and promising results. During two-stage revision, a temporary antibiotic-impregnated cement spacer was initially used for the local delivery of antibiotics, thereby reducing the risk of infection recurrence. Many researchers have reported various techniques for fabricating cemented spacers; however, there is no established standard technique. We share our cost-effective and easily reproducible technique for creating an articulated cemented spacer for managing infected THA...
March 26, 2024: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://read.qxmd.com/read/38531489/lower-rates-of-re-operation-following-partial-or-complete-revision-arthroplasty-compared-to-debridement-antibiotics-and-implant-retention-for-early-postoperative-and-acute-hematogenous-periprosthetic-hip-infection
#5
JOURNAL ARTICLE
Nicholas Tubin, Jonathan Bourget-Murray, Antoine Bureau, Jared Morris, Marisa Ann Azad, Hesham Abdelbary, George Grammatopoulos, Simon Garceau
INTRODUCTION: This study aimed to: 1) compare treatment outcomes between debridement, antibiotics, and implant retention (DAIR) and partial or complete revision arthroplasty (RA) for early postoperative and acute hematogenous total hip arthroplasty (THA) periprosthetic joint injection (PJI) and 2) identify factors associated with treatment outcome. METHODS: The study consisted of a retrospective cohort of patients who underwent surgery for PJI between 2004 and 2021...
March 24, 2024: Journal of Arthroplasty
https://read.qxmd.com/read/38529902/a-comparison-of-cemented-femoral-fixation-via-anterior-versus-posterior-approach-total-hip-arthroplasty-an-analysis-of-60-739-total-hip-arthroplasties
#6
JOURNAL ARTICLE
Wayne Hoskins, Sophie Corfield, Yi Peng, Stephen E Graves, Roger Bingham
BACKGROUND: Anterior approach total hip arthroplasty (THA) decreases the rate of dislocation but increases femoral-sided complications in the way of periprosthetic fractures and component loosening. A cemented prosthesis may reduce femoral-sided complications and improve the risk:benefit profile of anterior approach THA. METHODS: Data from the Australian National Joint Replacement Registry were analysed for patients undergoing primary THA via the anterior or posterior approach using a cemented polished femoral stem from January 2015 to December 2021...
March 26, 2024: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://read.qxmd.com/read/38529295/clinical-and-radiological-outcomes-and-analysis-of-failures-of-modular-revisions-stems-at-long-term-follow-up-a-systematic-review-and-meta-analysis
#7
JOURNAL ARTICLE
Michela Saracco, Vincenzo Ciriello, Andrea Fidanza, Giandomenico Logroscino
BACKGROUND: Increasingly hip replacements at young age exposes the patient to an increased risk of failure of the implant over the years. In case of failure, revision specific stems were designed to overcome bone loss. Modularity of these devices is an important resource for the surgeon as they allow the new implant to be better adapted to the patient's anatomy. The purpose of this systematic review is to provide data about the outcome at long-term follow-up (>8 years) of hip modular revision femoral stems...
2024: Annals of joint
https://read.qxmd.com/read/38528206/-dealing-with-early-complications-in-unicondylar-knee-arthroplasty-what-works-what-does-not
#8
REVIEW
Stefanie Donner, Michael Clarius
Complications in the early postoperative period following the implantation of a unicondylar knee arthroplasty (UKA) are both rare and rarely described in the literature. Often, only small case series or individual case reports are available. In this article, the most common complications of periprosthetic infection, periprosthetic tibial fracture, inlay dislocation and intra-articular cement residue in (loose bone cement body) are described and recommendations for conservative and surgical treatment are presented, including case examples...
March 25, 2024: Orthopadie (Heidelb)
https://read.qxmd.com/read/38528169/evaluation-of-time-to-reimplantation-as-a-risk-factor-in-two-stage-revision-with-static-spacers-for-periprosthetic-knee-joint-infection
#9
JOURNAL ARTICLE
Jan Puetzler, Marc Hofschneider, Georg Gosheger, Christoph Theil, Martin Schulze, Jan Schwarze, Raphael Koch, Burkhard Moellenbeck
INTRODUCTION: We investigated the time to reimplantation (TTR) during two-stage revision using static spacers with regard to treatment success and function in patients with chronic periprosthetic joint infection (PJI) of the knee. METHODS: 163 patients (median age 72 years, 72 women) who underwent two-stage exchange for chronic knee PJI between 2012 and 2020 were retrospectively analyzed (based on the 2011 Musculoskeletal Infection Society criteria). A cutoff TTR for increased risk of reinfection was identified using the maximally selected log-rank statistic...
March 25, 2024: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://read.qxmd.com/read/38526615/ninety-day-postoperative-mortality-and-complications-in-continuous-and-unselected-single-stage-revisions-for-chronic-periprosthetic-joint-infection
#10
JOURNAL ARTICLE
Chenchen Yang, Baochao Ji, Guoqing Li, Xiaogang Zhang, Boyong Xu, Li Cao
PURPOSE: Single-stage revision has gained significant attention as a major surgical approach for periprosthetic joint infection (PJI). However, the 90-day mortality and complication profile of single-stage revision is poorly characterized. The purposes of this study were to determine the incidence rates of and identify the risk factors for 90-day postoperative mortality and complications of single-stage revision for chronic PJI. METHODS: A retrospective review was conducted on patients who underwent single-stage revision for PJI between August 2000 and May 2022...
March 25, 2024: International Orthopaedics
https://read.qxmd.com/read/38525756/a-proposal-for-a-multidisciplinary-integrated-oral-health-network-for-patients-undergoing-major-orthopaedic-surgery-iohn-os
#11
JOURNAL ARTICLE
Matteo Briguglio, Thomas W Wainwright, Marialetizia Latella, Aurora Ninfa, Claudio Cordani, Cecilia Colombo, Giuseppe Banfi, Luca Francetti, Stefano Corbella
The passing of the years of life physiologically leads to the accumulation of changes in tissues in the oral cavity, influencing dentition, chewing and swallowing mechanisms, and the oral microbiota. Some diseases and medications can aggravate oral symptoms and negatively influence eating behaviours, increasing the likelihood of becoming malnourished. This could make older individuals more vulnerable to complications when undergoing major orthopaedic surgery. Hidden infection foci in the oral cavity are a recognised cause of post-operative periprosthetic joint infections...
March 19, 2024: Geriatrics
https://read.qxmd.com/read/38524868/the-potential-of-sheep-in-preclinical-models-for-bone-infection-research-a-systematic-review
#12
REVIEW
Michael L C Beagan, Chris H Dreyer, Louise K Jensen, Henrik E Jensen, Thomas E Andersen, Soeren Overgaard, Ming Ding
BACKGROUND: Reliable animal models are critical for preclinical research and should closely mimic the disease. With respect to route of infection, pathogenic agent, disease progression, clinical signs, and histopathological changes. Sheep have similar bone micro- and macrostructure as well as comparable biomechanical characteristics to humans. Their use in bone research is established, however their use in bone infection research is limited. This systematic review will summarise the key features of the available bone infection models using sheep, providing a reference for further development, validation, and application...
March 2024: Journal of Orthopaedic Translation
https://read.qxmd.com/read/38524719/diagnosis-and-prevention-of-periprosthetic-joint-infections-by-staphylococcus-aureus-after-hip-fracture-a-systematic-review-of-the-literature
#13
JOURNAL ARTICLE
Bianca Gabriella de Oliveira, Victor Hugo Ruis da Costa, Igor Rodrigues Gama, Murilo Halberstadt Beskow, Elisson Rafael Silva Dos Santos
Hip arthroplasties are surgical procedures widely performed all over the world, seeking to return functionality, relieve pain, and improve the quality of life of patients affected by osteoarthritis, femoral neck fractures, osteonecrosis of the femoral head, among other etiologies. Periprosthetic joint infections are one of the most feared complications due to the high associated morbidity and mortality, with a high number of pathogens that may be associated with its etiology. The aim of the present study was to analyze aspects correlated with the occurrence of infection, diagnosis and prevention of periprosthetic joint infections in the hip associated with Staphylococcus aureus after corrective surgery for hip fractures...
February 2024: Revista Brasileira de Ortopedia
https://read.qxmd.com/read/38522842/a-prospective-multicenter-evaluation-of-biofire%C3%A2-joint-infection-panel-for-the-rapid-microbiological-documentation-of-acute-arthritis
#14
JOURNAL ARTICLE
Gaillard Tiphaine, Dupieux-Chabert Céline, Roux Anne-Laure, Tessier Eve, Boutet-Dubois Adeline, Courboules Camille, Corvec Stéphane, Bémer Pascale, Lavigne Jean-Philippe, El Sayed Faten, Marchandin Hélène, Munier Clément, Chanard Emmanuel, Gazzano Vincent, Loiez Caroline, Laurent Frédéric
OBJECTIVES: To assess the performance of the rapid syndromic BioFire® Joint Infection panel (BF-JIP) to detect bacterial and fungal pathogens, as well as antibiotic resistance genes, directly in synovial fluid specimens collected in patients with acute arthritis. METHODS: The study was conducted in six French bacteriological laboratories. To assess the performances of BF-JIP, results were compared with those of synovial fluid 14-day culture, and in case of discrepancy, with those of complementary molecular methods and intraoperative samples...
March 22, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38521485/judicious-use-of-corticosteroid-injections-prior-to-shoulder-arthroplasty-does-not-compromise-outcomes-at-a-minimum-of-2-year-following-surgery
#15
JOURNAL ARTICLE
Benjamin J Cooper, Aaron Kesinger, Grace E Welch, Jordyn M Carroll, Adam Lutz, Ellen Shanley, Charles A Thigpen, Stefan J Tolan, Michael J Kissenberth, Stephan G Pill
BACKGROUND: The use of total shoulder arthroplasty is continuing to rise with its expanding indications. For patients with chronic conditions, such as glenohumeral arthritis and rotator cuff arthropathy, nonoperative treatment is typically done prior to arthroplasty and often includes corticosteroid injections. Recent studies in the shoulder arthroplasty literature as well as applied from the hip and knee literature have focused on the risk of periprosthetic infection. Literature is lacking as to whether the judicious use of corticosteroids in the year prior to arthroplasty influences patient reported outcomes...
March 21, 2024: Journal of Shoulder and Elbow Surgery
https://read.qxmd.com/read/38521249/minimum-2-year-outcomes-of-a-modern-monoblock-titanium-fluted-tapered-revision-stem-for-complex-primary-and-revision-total-hip-arthroplasty
#16
JOURNAL ARTICLE
Y Alqahtani, Lyndsay Somerville, Edward Vasharhelyi, James L Howard, Brent Lanting, Douglas D R Naudie, Steven J MacDonald, Richard W McCalden
INTRODUCTION: Modular titanium fluted tapered (TFT) stems have demonstrated excellent clinical success for femoral revision total hip arthroplasty (THA) surgery. This aim study reports the short-term outcomes of a novel modern monoblock TFT stem used for revision and complex primary THA with a minimum of 2 years of follow-up. METHODS: We identified 126 patients who received a single monoblock TFT stem; 26 patients for complex THA (failed fracture fixation) and 100 patients for revision THA...
March 21, 2024: Journal of Arthroplasty
https://read.qxmd.com/read/38521248/obesity-and-primary-total-hip-arthroplasty-the-absolute-versus-relative-risk-of-periprosthetic-joint-infection-at-15-years
#17
JOURNAL ARTICLE
Christopher N Carender, Kristin M Fruth, David G Lewallen, Daniel J Berry, Matthew P Abdel, Nicholas A Bedard
INTRODUCTION: To make an informed decision about total hip arthroplasty (THA), surgeons and patients need to understand the absolute and relative risks of periprosthetic joint infection (PJI). We sought to evaluate the long-term risk of PJI following primary THA stratified by body mass index (BMI) and PJI-related risk factors. METHODS: We identified 21,550 primary THAs performed from 2000 to 2021 at a single institution. Patients were stratified as having 0, 1, or ≥ 2 PJI risk factors (diabetes, chronic kidney disease, non-primary osteoarthritis, immunosuppression, or active smoking) and into BMI categories...
March 21, 2024: Journal of Arthroplasty
https://read.qxmd.com/read/38520549/are-silver-coated-megaprostheses-superior-to-uncoated-megaprostheses-in-managing-chronic-end-stage-periprosthetic-hip-and-knee-infection
#18
JOURNAL ARTICLE
Matías Vicente, Josep Nomdedeu, Kushal Lakhani, Pablo S Corona
INTRODUCTION: Outcomes for silver coated megaprostheses (SC-MP) used in cases of end-stage periprosthetic joint infection (PJI) have not been clearly defined. Although attractive, concerns over implant longevity and the risk of infection relapse exist among the scientific community. Therefore, we sought to investigate the effect of silver coating in lower-extremity MPs used in such difficult-to-treat scenarios. The study's primary hypothesis was that the periprosthetic infection control rate would be higher in patients with silver-coated implants...
March 23, 2024: Archives of Orthopaedic and Trauma Surgery
https://read.qxmd.com/read/38518960/periprosthetic-hip-and-knee-infection-is-an-ipsilateral-uninfected-total-joint-arthroplasty-at-risk
#19
JOURNAL ARTICLE
Daniel Karczewski, Harold I Salmons, Prabin Thapa, Aaron J Tande, Nicholas A Bedard, Daniel J Berry, Matthew P Abdel
INTRODUCTION: Periprosthetic joint infections (PJI) of total hip arthroplasty (THA) or total knee arthroplasty (TKA) may occur in the setting of an uninfected ipsilateral prosthetic joint. However, the risk to that uninfected ipsilateral joint is unknown. We analyzed the survivorship free from PJI in at risk THAs and TKAs following treatment of an ipsilateral knee or hip PJI, respectively. METHODS: Using our institutional total joint registry, we identified 205 patients who underwent treatment for PJI (123 THAs, 83 TKAs) with an at risk ipsilateral in situ knee or hip, respectively between 2000 and 2019...
March 20, 2024: Journal of Arthroplasty
https://read.qxmd.com/read/38518261/robotic-assisted-total-knee-arthroplasty-results-in-decreased-incidence-of-anterior-femoral-notching-compared-to-posterior-referenced-instrumented-total-knee-arthroplasty
#20
JOURNAL ARTICLE
MingYang Li, YongTao Zhang, ZhenShuai Shao, HaoXiang Zhu
OBJECTIVE: Periprosthetic fracture (PPF) is an uncommon but devastating complication after total knee arthroplasty (TKA). Anterior femoral notching (AFN) is one of a perioperative risk factor for PPF. The main purpose of this study was to compare between the rates of anterior femoral notching (AFN) and supracondylar periprosthetic femoral fracture (sPPF) of manual TKA and robotic arm-assisted TKA (RATKA). Meanwhile, blood loss, transfusion rates, inflammatory responses, complications, early clinical and radiological outcomes were also assessed...
2024: Journal of Orthopaedic Surgery
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