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Atypical depression and sleep medications

Surbhi Gupta, Andrea Caskey, Neelkamal Soares, Marilyn Augustyn
Sam is a 6-year-old boy with a diagnosis of autism spectrum disorder (ASD) who recently relocated and has an appointment with you, his new pediatric clinician, to establish care. He was previously followed by a psychiatrist for 2 years for additional diagnoses of insomnia, bipolar disorder, anxiety, attention deficit hyperactivity disorder, and intellectual disability. He has tried and (apparently) failed multiple psychotropic trials including stimulants, nonstimulants, mood stabilizers, atypical antipsychotics, and nonbenzodiazepine hypnotics...
July 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
Niraj Khatri Sapkota
Pitting edema is the clinical manifestation generally presented due to long standing, especially during summer in the sun, heavy weight bearing, vasodilatation, or cardio-hepatorenal disease or in rare hypothyroidism, but in atypical case may demonstrates depression with progressive stress, that also shows indication of mild pitting edema. We present a case of a non-alcoholic 42 years divorced male under anti-anxiety medication for 10 years who complained of weight gain almost 10 kg in 30 days duration, less attentive to his work, and always feel sleepiness during day (once get to sleep, slept more than 5 h during day) and also late up to morning if not called to wake-up, also with diminished memory, more specific event was before 60 days of these symptoms he unexpectedly suffered family tragedy suggesting depression led progressive stress pitting edema that got managed after appropriate counseling along with changes in his life style...
November 2017: International Journal of Health Sciences
Trang T H Tu, Anna Miura, Yukiko Shinohara, Lou Mikuzuki, Kaoru Kawasaki, Shiori Sugawara, Takayuki Suga, Takeshi Watanabe, Motoko Watanabe, Yojiro Umezaki, Tatsuya Yoshikawa, Haruhiko Motomura, Miho Takenoshita, Akira Toyofuku
OBJECTIVE: This study aimed (1) to investigate the differences in clinical characteristics of patients between 2 groups, those who have atypical odontalgia (AO) only and those who have AO with burning mouth syndrome (BMS), and (2) to assess the influence of psychiatric comorbidity factors on patients' experiences. METHOD: Medical records and psychiatric referral forms of patients visiting the Psychosomatic Dentistry Clinic of Tokyo Medical and Dental University between 2013 and 2016 were reviewed...
June 2018: Pain Practice: the Official Journal of World Institute of Pain
Dorothy K Sit, James McGowan, Christopher Wiltrout, Rasim Somer Diler, John Jesse Dills, James Luther, Amy Yang, Jody D Ciolino, Howard Seltman, Stephen R Wisniewski, Michael Terman, Katherine L Wisner
OBJECTIVE: Patients with bipolar disorder have recurrent major depression, residual mood symptoms, and limited treatment options. Building on promising pilot data, the authors conducted a 6-week randomized double-blind placebo-controlled trial to investigate the efficacy of adjunctive bright light therapy at midday for bipolar depression. The aims were to determine remission rate, depression symptom level, and rate of mood polarity switch, as well as to explore sleep quality. METHOD: The study enrolled depressed adults with bipolar I or II disorder who were receiving stable dosages of antimanic medication (excluding patients with hypomania or mania, mixed symptoms, or rapid cycling)...
February 1, 2018: American Journal of Psychiatry
Yuan Feng, Sha Sha, Chen Hu, Gang Wang, Gabor S Ungvari, Helen F K Chiu, Chee H Ng, Tian-Mei Si, Da-Fang Chen, Yi-Ru Fang, Zheng Lu, Hai-Chen Yang, Jian Hu, Zhi-Yu Chen, Yi Huang, Jing Sun, Xiao-Ping Wang, Hui-Chun Li, Jin-Bei Zhang, Yu-Tao Xiang
INTRODUCTION: Little has been reported about the demographic and clinical features of major depressive disorder (MDD) with comorbid dysthymia in Chinese patients. This study examined the frequency of comorbid dysthymia in Chinese MDD patients together with the demographic and clinical correlates and prescribing patterns of psychotropic drugs. METHODS: Consecutively collected sample of 1178 patients with MDD were examined in 13 major psychiatric hospitals in China...
March 2017: Asia-Pacific Psychiatry: Official Journal of the Pacific Rim College of Psychiatrists
Michael H Smolensky, Ramon C Hermida, Alain Reinberg, Linda Sackett-Lundeen, Francesco Portaluppi
Biological processes are organized in time as innate rhythms defined by the period (τ), phase (peak [Φ] and trough time), amplitude (A, peak-trough difference) and mean level. The human time structure in its entirety is comprised of ultradian (τ < 20 h), circadian (20 h > τ < 28 h) and infradian (τ > 28 h) bioperiodicities. The circadian time structure (CTS) of human beings, which is more complicated than in lower animals, is orchestrated and staged by a brain central multioscillator system that includes a prominent pacemaker - the suprachiasmatic nuclei of the hypothalamus...
2016: Chronobiology International
Brian Walitt, Petra Klose, Nurcan Üçeyler, Tudor Phillips, Winfried Häuser
BACKGROUND: This review is one of a series on drugs used to treat fibromyalgia. Fibromyalgia is a clinically well-defined chronic condition of unknown aetiology characterised by chronic widespread pain that often co-exists with sleep problems and fatigue. It affects approximately 2% of the general population. Up to 70% of patients with fibromyalgia meet the criteria for a depressive or anxiety disorder. People often report high disability levels and poor health-related quality of life...
June 2, 2016: Cochrane Database of Systematic Reviews
L Nyboe, C H Vestergaard, H Lund, M K Møller, P Videbech
OBJECTIVE: Studies on metabolic syndrome (MetS) in younger patients with depression are few. We examined the prevalence and progression of MetS in first-time hospitalized patients with depression during 1 year of follow-up. Furthermore, we explored putative risk factors of MetS. METHOD: We evaluated MetS and its components in first-time hospitalized patients with depression (N = 52) and healthy controls (N = 50) (18-45 years). Physical activity, aerobic fitness, sleeping disturbances, smoking and dietary habits, and psychopharmacological treatment were recorded at baseline for all participants and after 1 year for the patients...
March 2016: Acta Psychiatrica Scandinavica
David E Kemp
BACKGROUND: The most commonly used pharmacologic therapies for bipolar depression are mood stabilizers, atypical antipsychotics, and antidepressants. This paper reviews common side effects associated with these medications and provides recommendations for managing adverse medication effects in clinical practice. METHODS: Narrative review based on literature searches of Medline and evidence-based treatment guidelines for agents that have been approved by the US Food and Drug Administration and/or are commonly used to treat bipolar depression...
December 2014: Journal of Affective Disorders
Lauren K Lazowski, Ben Townsend, Emily R Hawken, Ruzica Jokic, Regina du Toit, Roumen Milev
BACKGROUND: Disturbance in sleep quality is a symptom of Major Depressive Disorder (MDD) and Bipolar Disorder (BD) and thus improving quality of sleep is an important aspect of successful treatment. Here, a prospective, double-blind, randomized, placebo-controlled study examined the effect of olanzapine (an atypical antipsychotic) augmentation therapy on sleep architecture, specifically slow wave sleep (SWS), in the treatment of depression. The effect of olanzapine augmentation therapy on other features of sleep (e...
July 17, 2014: BMC Psychiatry
A Maubert, C Hanon, J-P Metton
INTRODUCTION: Niemann-Pick type C disease (NPC) is a rare hereditary disease, which psychiatrists do not face often in France. Indeed, only a couple of articles specifically describing the psychiatric-disorders in the adult form have been published. And for the most part, they were not written by psychiatrists. This comprehensive international literature review aims at providing knowledge on this disease to French psychiatrists. METHODS: To achieve this literature review, we used the "PubMed" search engine, looking for the following keywords: Niemann-Pick type C AND (schizophrenia OR psychosis)...
October 2013: L'Encéphale
Toshiaki Hiraoka, Naoto Yamada
Sleep apnea syndrome (SAS) is characterized by apnea and hypopnea during sleep. SAS manifests various symptoms, and can become a risk factor for a variety of diseases. Typical psychiatric presentations of SAS are depressive symptoms, and those resembling negative symptoms in schizophrenia. We report two patients with schizophrenia spectrum disorders. Both patients showed the partial improvement of psychiatric symptoms with pharmacotherapy. After diagnosing comorbid SAS and subsequent treatment with continuous positive airway pressure (CPAP), the psychiatric symptoms improved...
2013: Seishin Shinkeigaku Zasshi, Psychiatria et Neurologia Japonica
Rosa Quelhas
OBJECTIVE: Parkinson's disease (PD) is a degenerative and disabling disease in which medical providers focus mainly on ameliorating problems in day-to-day functioning. This review summarizes current knowledge about the efficacy and tolerability of psychopharmacological agents in the treatment of depression, anxiety, psychosis, and insomnia in patients with PD. Recommended or promising nonpharmacological interventions are also reviewed. METHOD: Studies were identified using computerized searches, with further references obtained from the bibliographies of the reviewed articles...
March 2013: Journal of Psychiatric Practice
Chi-Un Pae, Soo-Jung Lee, Changsu Han, Ashwin A Patkar, Prakash S Masand
INTRODUCTION: Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder (FGID) that is characterised by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits. Although the pathophysiology of IBS is not fully understood, it is believed that psychiatric comorbidities are highly common in such patients. A variety of psychotropic medications are widely used in the treatment of IBS, particularly older antidepressants such as tricyclic antidepressants (TCAs)...
May 2013: Expert Opinion on Investigational Drugs
Sadeka Tamanna, M Iftekhar Ullah, Chelle R Pope, Garland Holloman, Christian A Koch
UNLABELLED: HASH(0x5635e23e2648) INTRODUCTION: Somnambulism or sleepwalking is a disorder of arousal from non-rapid eye movement sleep. The prevalence of sleep-related eating disorder has been found to be approximately between 1% and 5% among adults. Many cases of medication-related somnambulism and sleep-related eating disorder-like behavior have been reported in the literature. Quetiapine, an atypical antipsychotic medication, has been associated with somnambulism but has not yet been reported to be associated with sleep-related eating disorder...
2012: Journal of Medical Case Reports
Darryl Bassett
OBJECTIVE: Bipolar affective disorder and borderline personality disorder have long been considered to have significant similarities and comorbidity. This review endeavours to clarify the similarities and differences between these disorders, with an effort to determine whether they reflect different forms of the same illness or separate illness clusters. METHOD: The published literature relating to bipolar affective disorders, borderline personality disorders, and related areas of knowledge was reviewed using searches of several electronic databases (AMED, CINHAL, Embase, Ovid, ProQuest, MEDLINE, Web of Science, ScienceDirect) and published texts...
April 2012: Australian and New Zealand Journal of Psychiatry
F Oueriagli Nabih, M Touhami, A Laffinti, L Abilkacem
INTRODUCTION: Mefloquine (Lariam) is the drug of choice as malaria prophylaxis for travel to chloroquine-resistant areas. Severe neuropsychiatric side effects are rare. We report two clinical cases of mood disorders: mania and a major depressive episode with psychotic characteristics in two patients with mefloquine antimalarial prophylaxis. FIRST CLINICAL CASE: A 31-year-old man had taken mefloquine at a rate of 250mg/week as malaria prophylaxis for his mission in Democratic Republic of Congo...
October 2011: L'Encéphale
Raye Z Litten, Joanne B Fertig, Daniel E Falk, Megan L Ryan, Margaret E Mattson, Joseph F Collins, Cristin Murtaugh, Domenic Ciraulo, Alan I Green, Bankole Johnson, Helen Pettinati, Robert Swift, Maryam Afshar, Mary F Brunette, Nassima A-D Tiouririne, Kyle Kampman, Robert Stout
BACKGROUND: Despite advances in developing medications to treat alcohol dependence, few such medications have been approved by the Food and Drug Administration. Identified molecular targets are encouraging and can lead to the development and testing of new compounds. Atypical antipsychotic medications have been explored with varying results. Prior research suggests that the antipsychotic quetiapine may be beneficial in an alcohol-dependent population of very heavy drinkers. METHODS: In this double-blind, placebo-controlled trial, 224 alcohol-dependent patients who reported very heavy drinking were recruited across 5 clinical sites...
March 2012: Alcoholism, Clinical and Experimental Research
Ho-Kyoung Yoon, Yong-Ku Kim, Heon-Jeong Lee, Do-Young Kwon, Leen Kim
BACKGROUND: Atypical depression (AD) is considered a biologically and psychologically distinct subtype of depression. AD, contrary to melancholic depression (MD), may have different alteration in cytokine activity. AIMS: We aimed to investigate the differences of cytokine activity between AD patients and MD patients. Among psychiatric patients visited to the Psychiatry Department, Korea University Medical Center, 105 patients with major depression who met the Diagnostic and Statistical Manual (DSM-IV) criteria based on clinical interviews using a Structured Clinical Interview for DSM-IV were recruited...
June 2012: Nordic Journal of Psychiatry
Nancy Lutwak, Curt Dill
BACKGROUND: Post-menopausal women are at significant risk for coronary artery disease, have increased rates of depression compared to their male counterparts, and often present atypically with coronary insufficiency. The symptoms of depression and coronary ischemia overlap greatly. Complaints like fatigue, body aches, and sleep disturbance reported by a depressed elderly woman may be cardiac related and need to be investigated seriously without physician bias. OBJECTIVES: To ensure that clinicians are cautious when evaluating older women with a history of depression who are presenting with atypical complaints...
November 2012: Journal of Emergency Medicine
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