David O Riordan, Carole Elodie Aubert, Kieran A Walsh, Anette Van Dorland, Nicolas Rodondi, Robert S Du Puy, Rosalinde K E Poortvliet, Jacobijn Gussekloo, Carol Sinnott, Stephen Byrne, Rose Galvin, J Wouter Jukema, Simon P Mooijaart, Christine Baumgartner, Vera McCarthy, Elaine K Walsh, Tinh-Hai Collet, Olaf M Dekkers, Manuel R Blum, Patricia M Kearney
OBJECTIVES: To estimate and compare the prevalence and type of potentially inappropriate prescribing (PIP) and potential prescribing omissions (PPOs) among community-dwelling older adults (≥65 years) enrolled to a clinical trial in three European countries. DESIGN: A secondary analysis of the Thyroid Hormone Replacement for Subclinical Hypothyroidism Trial dataset. PARTICIPANTS: A subset of 48/80 PIP and 22/34 PPOs indicators from the Screening Tool of Older Persons Prescriptions/Screening Tool to Alert doctors to Right Treatment (STOPP/START) V2 criteria were applied to prescribed medication data for 532/737 trial participants in Ireland, Switzerland and the Netherlands...
March 22, 2018: BMJ Open