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Mamta Agiwal, Hu Jin
The millimeter-wave (mmWave) spectrum is one of the important propositions of 5G mobile networks due to its ability to accommodate massive traffic demands and an ever-increasing number of wireless devices. The beam-formed directional technique overcomes the propagation and path loss challenges of mmWave high frequencies. Though the directional convergence is expected to unleash new possibilities, it cannot be implemented with conventional power-saving solutions optimized over omnidirectional communications...
June 5, 2018: Sensors
Charlène Cool, Philippe Cestac, Cécile McCambridge, Laure Rouch, Philipe de Souto Barreto, Yves Rolland, Maryse Lapeyre-Mestre
AIMS: Potentially inappropriate drug prescribing (PIDP) is frequent in nursing home (NH) residents. We aimed to investigate whether a geriatric intervention on quality of care reduced PIDP. METHODS: We performed an ancillary study within a multicentric individually-tailored controlled trial (IQUARE trial). All NH received a baseline and 18-month audit regarding drug prescriptions and other quality of care indicators. After the initial audit, NHs of the intervention group benefited of an in-site intervention (geriatric education for NH staff) provided by a geriatrician from the closest hospital...
July 2018: British Journal of Clinical Pharmacology
Sophia Hannou, Pierre Voirol, André Pannatier, Marie-Laure Weibel, Farshid Sadeghipour, Armin von Gunten, Jean-Frédéric Mall, Isabella De Giorgi Salamun
Background Prescribing for the elderly is challenging. A previous observational study conducted in our geriatric psychiatry admission unit (GPAU) using STOPP/START criteria showed a high number of potentially inappropriate drug prescriptions (PIDPs). A clinical pharmacist was added to our GPAU as a strategy to reduce PIDPs. Objective The objective of the present study was to assess the impact of a clinical pharmacist on PIDPs by measuring acceptance rates of pharmacist interventions (PhIs). Setting This study was conducted at the GPAU of Lausanne University Hospital...
December 2017: International Journal of Clinical Pharmacy
Karin A Rosenblatt, Elaina F Osterbur, Jeffrey A Douglas
OBJECTIVE: To determine the association between Pap smear and pelvic examination screenings and the development of invasive cervical cancer in a Medicare population using a matched case-control design. METHODS: Matched case-control data sets were constructed from the SEER-Medicare database that links the Surveillance Epidemiology End Results (SEER) cancer registry data and Medicare enrollment and claims data of subjects who received care between the years 1991 and 1999 aged 65years or older...
September 2016: Gynecologic Oncology
Charlène Cool, Philippe Cestac, Charlotte Laborde, Cécile Lebaudy, Laure Rouch, Benoit Lepage, Bruno Vellas, Philipe de Souto Barreto, Yves Rolland, Maryse Lapeyre-Mestre
IMPORTANCE: Polymedication is frequent in nursing home (NH) residents. This increases the risk of potentially inappropriate drug prescribing (PIDP), which can lead to adverse drug events, such as falls and hospitalization. OBJECTIVE: To identify PIDP in NH residents and to investigate subject-related and NH structural and organizational factors associated with PIDP. DESIGN: Cross-sectional study. SETTING: A total of 175 NHs in Midi-Pyrénées region, South-Western France...
2014: Journal of the American Medical Directors Association
Yan Wang, Shineng Luo, Jianguo Lin, Ling Qiu, Wen Cheng, Haozhen Zhai, Beibei Nan, Wanzhong Ye, Yongmei Xia
This study was to investigate the preparation and biodistribution of (99m)Tc-labeled novel zoledronic acid derivative 1-hydroxy-2-(2-isopropyl-1H-imidazole-1-yl) ethylidene-1,1-bisphosphonic ((99m)Tc-i-PIDP) as a potential bone imaging agent. Satisfactory labeling results (radiochemical purity over 95%) were obtained when the amount of i-PIDP, Na(99m)TcO(4), and SnCl(2)·2H(2)O, were 5 mg, 37 MBq, and 100 μg, respectively, the pH value was between 4.0 and 6.0, and the labeling reaction continued for 30 min...
September 2011: Applied Radiation and Isotopes
Carmelinda Ruggiero, Giuseppina Dell'Aquila, Beatrice Gasperini, Graziano Onder, Fabrizia Lattanzio, Stefano Volpato, Andrea Corsonello, Cinzia Maraldi, Roberto Bernabei, Antonio Cherubini
BACKGROUND: Potentially inappropriate medications in older patients increase the risk of adverse drug events, which are an important cause of hospital admission and death among hospitalized patients. Little information is available about the prevalence of potentially inappropriate drug prescriptions (PIDPs) and the related health adverse outcomes among nursing home (NH) residents. OBJECTIVE: To estimate the prevalence of PIDPs and the association with adverse outcomes in NH residents...
September 1, 2010: Drugs & Aging
Carmelinda Ruggiero, Fabrizia Lattanzio, Giuseppina Dell'Aquila, Beatrice Gasperini, Antonio Cherubini
Older people take up a large proportion of health care, including drugs, and evidence shows that drug prescribing to this group is often inappropriate. Negative consequences of potential inappropriate drug prescription (PIDP) include adverse drug events, high healthcare service utilization and high costs for the patients and society. Although nursing home residents are the most vulnerable persons exposed to PIDP, few observational studies have investigated the prevalence, the factors associated with and the consequences of PIDP...
December 2009: Drugs & Aging
Yongxin Yang, Zhenghong Xu, Jingui Jiang, Yu Gao, Wangwen Gu, Lingli Chen, Xiaozheng Tang, Yaping Li
A new cationic derivate of polyphosphazene with imidazole and 2-dimethylaminoethylamino (DMAEA) as side groups, poly(imidazole/DMAEA)phosphazene (PIDP), was synthesized and investigated for gene delivery. The half-lives of PIDP degradation under neutral (pH 7.4) and acidic conditions (pH 5.0) were 22 and 3 days at 37 degrees C, respectively. The cytotoxicity of PIDP assayed by MTT was much lower than that of poly(2-dimethylaminoethylamino)phosphazene (PDAP) and PEI 25K. PIDP could condense DNA into nanoparticles with a size around 100 nm and zeta potential (+25 mV) at the ratio of 10:1 (PIDP/DNA, w/w)...
May 8, 2008: Journal of Controlled Release: Official Journal of the Controlled Release Society
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