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PIAs- (Potentially Inappropriate Associations)

Maria Michela Gianino, Jacopo Lenzi, Marco Bonaudo, Maria Pia Fantini, Walter Ricciardi, Gianfranco Damiani
BACKGROUND: This study analyzes the trajectories of antibiotic consumption using different indicators of patients' socioeconomic status, category and age-group of physicians. METHODS: This study uses a pooled, cross-sectional, time series analysis. The data focus on 22 European countries from 2000 to 2014 and were obtained from the European Center for Disease and Control, Organization for Economic Co-operation and Development, Eurostat and Global Economic Monitor...
2018: PloS One
Irène Pandraud-Riguet, Dominique Bonnet-Zamponi, Elsa Bourcier, Marion Buyse, Sandra Laribe-Caget, Patrick Frémont, Eric Pautas, Christiane Verny, Patrick Hindlet, Christine Fernandez
OBJECTIVES: To determine whether potentially inappropriate medications (PIMs) or potentially inappropriate associations (PIAs) prescribed knowingly are associated with patient monitoring. DESIGN: Prospective observational study. SETTING: Geriatric units (n = 56) in 28 hospitals. PARTICIPANTS: Inpatients aged 75 and older (N = 1,327). MEASUREMENTS: Potentially inappropriate prescriptions (PIP) were defined as a PIM or a PIA selected by an expert board from lists of explicit criteria (Beers, Priscus, Laroche, French Health Agency) using a Delphi process...
December 2017: Journal of the American Geriatrics Society
Pia Paffenholz, Isabel Maria Heidegger, Kathrin Kuhr, Sven Heiko Loosen, David Pfister, Axel Heidenreich
INTRODUCTION: The management of testicular cancer (TC) requires a complex multimodal therapeutic approach. Despite the availability of regularly updated guidelines, non-guideline-concordant treatment of TC still occurs. The purpose of the present study was to evaluate the compliance patterns in diagnosis and therapy and their potential effects on patient outcomes with respect to the guidelines of the European Association of Urology. PATIENTS AND METHODS: We performed a retrospective analysis of 131 patients diagnosed with TC who had been referred to our department from September 2015 to October 2016...
September 6, 2017: Clinical Genitourinary Cancer
Camila Arellano, Gabriela Saldivia, Pía Córdova, Pola Fernández, Felipe Morales, Mariela López, Lorenzo Villa
OBJECTIVES: To assess and compare the prevalence of prescribing of potentially inappropriate medications (PIMs) identified using the Beers and STOPP criteria; and to determine the clinical variables related with the prescription of PIMs in older adults. METHODS: An observational study of 250 patients aged 65 years or older was conducted in a large teaching hospital. Beers (2012) and STOPP (2008) criteria were utilized to identify PIMs. Data on age, sex, admission and discharge dates, diagnoses, and medications prescribed were obtained from medical records...
November 2016: Archives of Gerontology and Geriatrics
Pia Touboul-Lundgren, Siri Jensen, Johann Drai, Morten Lindbæk
BACKGROUND: Inappropriate antibiotic prescribing, particularly for respiratory tract infections (RTI) in ambulatory care, has become a worldwide public health threat due to resulting antibiotic resistance. In spite of various interventions and campaigns, wide variations in antibiotic use persist between European countries. Cultural determinants are often referred to as a potential cause, but are rarely defined. To our knowledge, so far no systematic literature review has focused on cultural determinants of antibiotic use...
2015: BMC Public Health
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