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Magnesium AND (migraine OR migraines OR migraineur)

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https://read.qxmd.com/read/30764890/vitamins-and-minerals-for-migraine-prophylaxis-a-systematic-review-and-meta-analysis
#1
George N Okoli, Rasheda Rabbani, Hessam H Kashani, Aleksandra K Wierzbowski, Christine Neilson, Behzad Mansouri, Ryan Zarychanski, Ahmed M Abou-Setta
OBJECTIVE: To summarize the findings of randomized controlled trials (RCTs) on the efficacy and safety of vitamins and minerals for migraine prophylaxis. METHODS: We systematically searched bibliographic databases and relevant websites for parallel and crossover RCTs reporting efficacy and/or safety of vitamins and/or minerals for migraine prophylaxis. Our primary outcomes were migraine frequency (number of attacks) and duration (hours). Secondary outcomes were severity (intensity), days with migraine, and adverse events...
February 15, 2019: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/30685601/experiences-of-an-outpatient-infusion-center-with-intravenous-magnesium-therapy-for-status-migrainosus
#2
Fanny Xu, Anush Arakelyan, Andrew Spitzberg, Lauren Green, Paul-Henri Cesar, Anne Csere, Olive Nworie, Soma Sahai-Srivastava
OBJECTIVES: Exploratory study to investigate the effectiveness of intravenous magnesium as an abortive for status migrainosus in an outpatient infusion center, and characterize the patients who benefit from the therapy. PATIENTS & METHODS: Retrospective analysis of 234 migraine patients who received IV magnesium as a headache abortive, at the headache clinic of University of Southern California. Additional intramuscular (IM) injections for nausea (prochlorperazine, odansetron, metoclopramide) or for refractory pain (ketorolac, dexamethasone, sumatriptan, dihydroergotamine), were administered as necessary...
January 21, 2019: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/30684032/magnesium-and-health-outcomes-an-umbrella-review-of-systematic-reviews-and-meta-analyses-of-observational-and-intervention-studies
#3
Nicola Veronese, Jacopo Demurtas, Gabriella Pesolillo, Stefano Celotto, Tommaso Barnini, Giovanni Calusi, Maria Gabriella Caruso, Maria Notarnicola, Rosa Reddavide, Brendon Stubbs, Marco Solmi, Stefania Maggi, Alberto Vaona, Joseph Firth, Lee Smith, Ai Koyanagi, Ligia Dominguez, Mario Barbagallo
PURPOSE: To map and grade all health outcomes associated with magnesium (Mg) intake and supplementation using an umbrella review. METHODS: Umbrella review of systematic reviews with meta-analyses of observational studies and randomized controlled trials (RCTs) using placebo/no intervention as control group. We assessed meta-analyses of observational studies based on random-effect summary effect sizes and their p values, 95% prediction intervals, heterogeneity, small-study effects and excess significance...
January 25, 2019: European Journal of Nutrition
https://read.qxmd.com/read/30600979/migraine-headache-prophylaxis
#4
Hien Ha, Annika Gonzalez
Migraines impose significant health and financial burdens. Approximately 38% of patients with episodic migraines would benefit from preventive therapy, but less than 13% take prophylactic medications. Preventive medication therapy reduces migraine frequency, severity, and headache-related distress. Preventive therapy may also improve quality of life and prevent the progression to chronic migraines. Some indications for preventive therapy include four or more headaches a month, eight or more headache days a month, debilitating headaches, and medication-overuse headaches...
January 1, 2019: American Family Physician
https://read.qxmd.com/read/30403400/migraine-treatment-in-pregnant-women-presenting-to-acute-care-a-retrospective-observational-study
#5
Katherine T Hamilton, Matthew S Robbins
OBJECTIVE: To assess the acute treatment of pregnant women presenting to a hospital with migraine. BACKGROUND: Migraine is a common problem in pregnancy; however, migraine treatment is challenging in pregnant women for fears of medication teratogenicity and lack of data in this population. To date, no study has directly explored physician practices for treatment of acute migraine in pregnant women. METHODS: We conducted a retrospective chart review of medication administration for pregnant women who presented to an acute care setting with a migraine attack and received neurology consultation between 2009 and 2014...
November 7, 2018: Headache
https://read.qxmd.com/read/30291554/episodic-migraine-with-and-without-aura-key-differences-and-implications-for-pathophysiology-management-and-assessing-risks
#6
REVIEW
Angeliki Vgontzas, Rebecca Burch
PURPOSE OF REVIEW: To review the pathophysiologic, epidemiologic, and clinical evidence for similarities and differences between migraine with and without aura. RECENT FINDINGS: The ICHD-3 has recently refined the diagnostic criteria for aura to include positive symptomatology, which better differentiates aura from TIA. Although substantial evidence supports cortical spreading depression as the cause of visual aura, the role (if any) of CSD in headache pain is not well understood...
October 5, 2018: Current Pain and Headache Reports
https://read.qxmd.com/read/30198804/treating-status-migrainosus-in-the-emergency-setting-what-is-the-best-strategy
#7
REVIEW
László Vécsei, Délia Szok, Aliz Nyári, János Tajti
Migraine is a disabling primary headache disorder with unknown exact pathomechanism. Status migrainosus (SM) is a complication of migraine (with or without aura), representing an attack that lasts for more than 72 h. There is a paucity of data published with regard to its pathomechanism and therapeutic options. Areas covered: The authors review the literature on SM from PubMed published between 1999 and January 2018. The authors specifically look at the therapeutic possibilities of SM in the emergency department in patients that have or have not already been treated with serotonergic agents...
October 2018: Expert Opinion on Pharmacotherapy
https://read.qxmd.com/read/30074549/preventive-therapy-of-migraine
#8
Todd J Schwedt
PURPOSE OF REVIEW: This article reviews the preventive therapy of migraine, including indications, strategies for use, and available treatments. RECENT FINDINGS: Lifestyle modifications and migraine trigger avoidance are recommended as preventive measures for all individuals with migraine. The decision to recommend additional migraine preventive therapy should consider the frequency of migraine attacks and headaches, extent of migraine-associated disability, frequency of using acute migraine treatments and the responsiveness to such treatments, and patient preferences...
August 2018: Continuum: Lifelong Learning in Neurology
https://read.qxmd.com/read/29882776/the-role-of-magnesium-in-neurological-disorders
#9
REVIEW
Anna E Kirkland, Gabrielle L Sarlo, Kathleen F Holton
Magnesium is well known for its diverse actions within the human body. From a neurological standpoint, magnesium plays an essential role in nerve transmission and neuromuscular conduction. It also functions in a protective role against excessive excitation that can lead to neuronal cell death (excitotoxicity), and has been implicated in multiple neurological disorders. Due to these important functions within the nervous system, magnesium is a mineral of intense interest for the potential prevention and treatment of neurological disorders...
June 6, 2018: Nutrients
https://read.qxmd.com/read/29849626/magnesium-and-human-health-perspectives-and-research-directions
#10
REVIEW
Abdullah M Al Alawi, Sandawana William Majoni, Henrik Falhammar
Magnesium is the fourth most abundant cation in the body. It has several functions in the human body including its role as a cofactor for more than 300 enzymatic reactions. Several studies have shown that hypomagnesemia is a common electrolyte derangement in clinical setting especially in patients admitted to intensive care unit where it has been found to be associated with increase mortality and hospital stay. Hypomagnesemia can be caused by a wide range of inherited and acquired diseases. It can also be a side effect of several medications...
2018: International Journal of Endocrinology
https://read.qxmd.com/read/29619575/the-evidence-for-the-role-of-nutraceuticals-in-the-management-of-pediatric-migraine-a-review
#11
REVIEW
Serena L Orr
PURPOSE OF REVIEW: Nutraceuticals are a form of complementary and alternative medicine that is commonly used by children and adolescents with migraine. In this review, observational studies, randomized controlled trials, systematic reviews, and meta-analyses on the efficacy and safety of single compound nutraceuticals for the management of migraine in children and adolescents were identified through a literature search of MEDLINE, Embase, and EBM Reviews-Cochrane Central Register of Controlled Trials...
April 4, 2018: Current Pain and Headache Reports
https://read.qxmd.com/read/29571016/the-role-of-nutrients-in-the-pathogenesis-and-treatment-of-migraine-headaches-review
#12
REVIEW
Elyas Nattagh-Eshtivani, Mahmood Alizadeh Sani, Monireh Dahri, Faezeh Ghalichi, Abed Ghavami, Pishva Arjang, Ali Tarighat-Esfanjani
OBJECTIVE: Migraine as a disabling neurovascular disease affects 6% of men and 18% of women worldwide. The deficiency of many nutrients including magnesium, niacin, riboflavin, cobalamin, coenzymes Q10, carnitine, α-lipoic acid and vitamin D is associated with migraine. Some researchers postulate that mitochondrial dysfunction and impaired antioxidant status can cause migraine. Also increase in homocysteine level can lead to migraine attacks; therefore, some Nutraceuticals play a vital role in migraine prevention...
June 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://read.qxmd.com/read/29515282/magnesium-valproate-induced-pedal-edema-on-chronic-therapy-a-rare-adverse-drug-reaction
#13
Himani Prajapati, Dinesh Kansal, Rajan Negi
Valproate-related pedal edema is usually regarded as a problem occurring after long-term administration of valproate. Valproate has been a drug of choice for the treatment of generalized or partial seizures as monotherapy or adjunctive therapy, bipolar disorder, for the prophylaxis of migraine headache in adults. This case report described patient-acquiring bilateral pedal edema after long-term use of magnesium valproate. Discontinuing valproate resulted in rapid improvement of the condition. This adverse reaction to the best of our knowledge is first reported a case of bilateral pedal edema cause by magnesium valproate in low dose...
September 2017: Indian Journal of Pharmacology
https://read.qxmd.com/read/29508147/glutamate-and-its-receptors-as-therapeutic-targets-for-migraine
#14
REVIEW
Jan Hoffmann, Andrew Charles
There is substantial evidence indicating a role for glutamate in migraine. Levels of glutamate are higher in the brain and possibly also in the peripheral circulation in migraine patients, particularly during attacks. Altered blood levels of kynurenines, endogenous modulators of glutamate receptors, have been reported in migraine patients. Population genetic studies implicate genes that are involved with glutamate signaling in migraine, and gene mutations responsible for familial hemiplegic migraine and other familial migraine syndromes may influence glutamate signaling...
April 2018: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://read.qxmd.com/read/29131326/magnesium-in-migraine-prophylaxis-is-there-an-evidence-based-rationale-a-systematic-review
#15
REVIEW
Alexander von Luckner, Franz Riederer
OBJECTIVE: The primary objective was to systematically evaluate the existing evidence base on magnesium in migraine prophylaxis. METHODS: The search for clinical trials published from 1990 to 2016 was separately conducted by AvL and FR using standard search terms as well as MeSh terms on PubMed and EMBASE. Randomized, double-blind, placebo-controlled trials investigating prophylactic magnesium administration in migraineurs aged 18-65 were considered eligible. In a mutual effort, the studies found were sorted and analyzed under consideration of the guidelines for controlled trials for drugs in migraine by the International Headache Society and using predefined eligibility criteria...
February 2018: Headache
https://read.qxmd.com/read/29093983/the-importance-of-magnesium-in-clinical-healthcare
#16
REVIEW
Gerry K Schwalfenberg, Stephen J Genuis
The scientific literature provides extensive evidence of widespread magnesium deficiency and the potential need for magnesium repletion in diverse medical conditions. Magnesium is an essential element required as a cofactor for over 300 enzymatic reactions and is thus necessary for the biochemical functioning of numerous metabolic pathways. Inadequate magnesium status may impair biochemical processes dependent on sufficiency of this element. Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for magnesium, a deficiency problem contributing to various health conditions...
2017: Scientifica
https://read.qxmd.com/read/29065085/resolution-of-persistent-post-stapedotomy-vertigo-with-migraine-prophylactic-medication
#17
Omid Moshtaghi, Hossein Mahboubi, Yarah M Haidar, Ronald Sahyouni, Harrison W Lin, Hamid R Djalilian
OBJECTIVE: To describe persistent post-stapedotomy vertigo (PSV) and its treatment using migraine prophylaxis. PATIENTS: A retrospective review of all patients with persistent PSV spanning 10 years at a tertiary academic hospital was performed. Patients who experienced persistent vertigo for a minimum of 3 months after surgery were included. Those with possible perilymph fistula, long prosthesis, and benign paroxysmal positional vertigo were excluded. INTERVENTIONS: All patients received instructions on migraine dietary and lifestyle changes and Vitamin B2 and magnesium...
December 2017: Otology & Neurotology
https://read.qxmd.com/read/28854909/a-combination-of-coenzyme-q10-feverfew-and-magnesium-for-migraine-prophylaxis-a-prospective-observational-study
#18
Angèle Guilbot, Marie Bangratz, Samira Ait Abdellah, Christian Lucas
BACKGROUND: Feverfew (Tanacetum parthenium L.), magnesium and coenzyme Q10 are frequently used for migraine prophylaxis. Supplementation with a fixed combination of these three agents (Antemig®, PiLeJe) was investigated in an observational study. METHODS: Adult patients suffering from migraine according to the criteria of the International Headache Society were enrolled by general practitioners (≥2 migraine attacks during previous month; exclusion of chronic migraine and medication overuse) and after a one-month baseline phase, supplemented with one tablet of 100 mg feverfew, 100 mg coenzyme Q10 and 112...
August 30, 2017: BMC Complementary and Alternative Medicine
https://read.qxmd.com/read/28757917/intravenous-caffeine-citrate-vs-magnesium-sulfate-for-reducing-pain-in-patients-with-acute-migraine-headache-a-prospective-quasi-experimental-study
#19
Alireza Baratloo, Sahar Mirbaha, Hossein Delavar Kasmaei, Pooya Payandemehr, Ahmed Elmaraezy, Ahmed Negida
BACKGROUND: Current evidence suggests that intravenous magnesium sulfate might be effective for reducing migraine pain. In a recent pilot study, we showed that intravenous caffeine citrate could reduce the severity of migraine headache. The objective of this study is to investigate the efficacy of intravenous caffeine citrate vs. magnesium sulfate for management of acute migraine headache. METHODS: We conducted a prospective quasi-experimental study from January until May 2016 in two educational medical centers of Shahid Beheshti University of Medical Sciences (Shoahadaye Tajrish Hospital and Imam Hossein Hospital), Tehran, Iran...
July 2017: Korean Journal of Pain
https://read.qxmd.com/read/28527085/the-use-of-nutraceutics-in-children-s-and-adolescent-s-headache
#20
R Sangermani, A Boncimino
Nutraceutics are the most used non-pharmacological remedies for migraine's prophylaxis in children and adolescents. Doctors interested in use of nutraceuticals for a complete treatment of children's headache should be adequately informed on this treatments' efficacy and safety. Actually there is a lack of official guidelines about use of nutraceuticals in migraine's prevention in children and adolescent and there are few studies with limited efficacy evidences. The most used nutraceuticals for adolescent's and children's headache prophylaxis are: magnesium, coenzyme Q10, riboflavin, butterbur, feverfew and melatonin...
May 2017: Neurological Sciences
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