keyword
https://read.qxmd.com/read/38571218/legget-garg-inequality-for-a-two-mode-entangled-bosonic-system
#1
JOURNAL ARTICLE
Joanna K Kalaga, Anna Kowalewska-Kudłaszyk, Wiesław Leoński, Jan Peřina
We discuss a model of two nonlinear quantum oscillators mutually coupled by linear interaction and continuously driven by external coherent excitation. For such a system, we analyze temporal correlations. We examine the violation of the Leggett-Garg inequality analysing various scenarios of measurements. These scenarios are based on the projection onto different Bell states. We show that the possibility of violation of the Leggett-Garg inequalities is associated with the use of different projectors.
March 11, 2024: Optics Express
https://read.qxmd.com/read/38507819/prevention-of-metastasis-by-suppression-of-stemness-genes-using-a-combination-of-micrornas
#2
JOURNAL ARTICLE
Kseniya V Nevskaya, Alexandra G Pershina, Ekaterina S Hmelevskaya, Lina V Efimova, Marina K Ibragimova, Darya S Dolgasheva, Irina A Tsydenova, Alexander A Ufandeev, Evgeny E Buyko, Ekaterina A Perina, Ksenia A Gaptulbarova, Ekaterina A Kravtsova, Sergei V Krivoshchekov, Vladimir V Ivanov, Artem M Guriev, Elena V Udut, Nikolai V Litviakov
We propose an original strategy for metastasis prevention using a combination of three microRNAs that blocks the dedifferentiation of cancer cells in a metastatic niche owing to the downregulation of stemness genes. Transcriptome microarray analysis was applied to identify the effects of a mixture of microRNAs on the pattern of differentially expressed genes in human breast cancer cell lines. Treatment of differentiated CD44- cancer cells with the microRNA mixture inhibited their ability to form mammospheres in vitro...
March 20, 2024: Journal of Medicinal Chemistry
https://read.qxmd.com/read/38501507/detection-of-insulin-oligomeric-forms-by-a-novel-surface-plasmon-resonance-diffusion-coefficient-based-approach
#3
JOURNAL ARTICLE
Damiano Calcagno, Maria Luisa Perina, Gabriele Antonio Zingale, Irene Pandino, Nunzio Tuccitto, Valentina Oliveri, Maria Cristina Parravano, Giuseppe Grasso
Insulin is commonly used to treat diabetes and undergoes aggregation at the site of repeated injections in diabetic patients. Moreover, aggregation is also observed during its industrial production and transport and should be avoided to preserve its bioavailability to correctly adjust glucose levels in diabetic patients. However, monitoring the effect of various parameters (pH, protein concentration, metal ions, etc.) on the insulin aggregation and oligomerization state is very challenging. In this work, we have applied a novel Surface Plasmon Resonance (SPR)-based experimental approach to insulin solutions at various experimental conditions, monitoring how its diffusion coefficient is affected by pH and the presence of metal ions (copper and zinc) with unprecedented sensitivity, precision, and reproducibility...
April 2024: Protein Science
https://read.qxmd.com/read/38471637/retrospective-analysis-of-factors-associated-with-umbilical-diseases-in-foals
#4
JOURNAL ARTICLE
F Perina, J Mariella, N Ellero, F Freccero, C Castagnetti, A Lanci
In neonatal foals, umbilical remnants can be affected by infectious and non-infectious diseases. This study aimed to retrospectively evaluate historical, management and clinical factors that may be related to the occurrence of umbilical remnant diseases. Clinical reports of foals born or hospitalized within 24h of life during the 2017-2021 foaling seasons were reviewed. Forty/183 foals (21.9%) developed umbilical remnant diseases (URD group), while 143/183 foals (78.1%) had normal umbilical remnants (NUR group)...
March 10, 2024: Journal of Equine Veterinary Science
https://read.qxmd.com/read/38332213/five-years-after-the-collapse-of-the-fund%C3%A3-o-dam-lessons-from-temporal-monitoring-of-chemistry-and-acute-toxicity
#5
JOURNAL ARTICLE
Guacira de Figueiredo Eufrasio Pauly, Fernando Cesar Perina, Flávia Yoshie Yamamoto, Bianca Sung Mi Kim, Tailisi Hoppe Trevizani, Ana Carolina Feitosa Cruz, Caio Cesar Ribeiro, Luciana Menezes, Rubens Cesar Lopes Figueira, Denis Moledo de Souza Abessa
In November 2015, the Fundão Dam break released millions of tons of metal-rich tailings into the Doce River Basin (DRB), causing catastrophic damage and potential ecological effects that reached the Atlantic Ocean. This study aimed to evaluate the geochemistry and toxicity of water and sediments collected in the DRB from 2015 to 2019 and to determine the spatial and temporal trends. Water and sediment samples were analyzed for metals and As by inductively coupled plasma optical emission spectrometry (ICP-OES), and acute toxicity for Daphnia similis or D...
February 9, 2024: Environmental Monitoring and Assessment
https://read.qxmd.com/read/38273563/groundwater-is-a-hidden-global-keystone-ecosystem
#6
REVIEW
Mattia Saccò, Stefano Mammola, Florian Altermatt, Roman Alther, Rossano Bolpagni, Anton Brancelj, David Brankovits, Cene Fišer, Vasilis Gerovasileiou, Christian Griebler, Simone Guareschi, Grant C Hose, Kathryn Korbel, Elisabeth Lictevout, Florian Malard, Alejandro Martínez, Matthew L Niemiller, Anne Robertson, Krizler C Tanalgo, Maria Elina Bichuette, Špela Borko, Traian Brad, Matthew A Campbell, Pedro Cardoso, Fulvio Celico, Steven J B Cooper, David Culver, Tiziana Di Lorenzo, Diana M P Galassi, Michelle T Guzik, Adam Hartland, William F Humphreys, Rodrigo Lopes Ferreira, Enrico Lunghi, Daniele Nizzoli, Giulia Perina, Rajeev Raghavan, Zoe Richards, Ana Sofia P S Reboleira, Melissa M Rohde, David Sánchez Fernández, Susanne I Schmidt, Mieke van der Heyde, Louise Weaver, Nicole E White, Maja Zagmajster, Ian Hogg, Albert Ruhi, Marthe M Gagnon, Morten E Allentoft, Robert Reinecke
Groundwater is a vital ecosystem of the global water cycle, hosting unique biodiversity and providing essential services to societies. Despite being the largest unfrozen freshwater resource, in a period of depletion by extraction and pollution, groundwater environments have been repeatedly overlooked in global biodiversity conservation agendas. Disregarding the importance of groundwater as an ecosystem ignores its critical role in preserving surface biomes. To foster timely global conservation of groundwater, we propose elevating the concept of keystone species into the realm of ecosystems, claiming groundwater as a keystone ecosystem that influences the integrity of many dependent ecosystems...
January 2024: Global Change Biology
https://read.qxmd.com/read/38221391/the-systematics-of-the-pseudoscorpion-genus-indohya-pseudoscorpiones-hyidae-in-australia
#7
JOURNAL ARTICLE
Mark S Harvey, Mieke A A Burger, Kym M Abrams, Terrie L Finston, Joel A Huey, Giulia Perina
The pseudoscorpion genus Indohya Beier, 1974 is known to occur in three Gondwanan fragments around the Indian Oceansouthern India, Madagascar and north-western Australiasuggesting that the genus had evolved prior to the breakup of Gondwana and was present on each landmass as they rifted apart during the Mesozoic. The Australian fauna is the most diverse, with nine species previously described from Cape Range and the Kimberley region of north-western Australia. The present study documents the genus Indohya in Australia using a combination of morphology and DNA sequence data...
September 5, 2023: Zootaxa
https://read.qxmd.com/read/38175081/generalized-sub-poissonian-states-of-two-beam-fields
#8
JOURNAL ARTICLE
Jan Peřina, Kishore Thapliyal, Ondřej Haderka, Václav Michálek, Radek Machulka
Two-beam states obtained by partial photon-number-resolving detection in one beam of a multi-mode twin beam are experimentally investigated using an intensified CCD camera. In these states, sub-Poissonian photon-number distributions in one beam are accompanied by sub-shot-noise fluctuations in the photon-number difference of both beams. Multi-mode character of the twin beam implying the beam nearly Poissonian statistics is critical for reaching sub-Poissonian photon-number distributions, which contrasts with the use of a two-mode squeezed vacuum state...
January 1, 2024: Optics Express
https://read.qxmd.com/read/38124401/effects-of-different-ficus-feeding-experiences-on-host-preference-of-perina-nuda-larvae-lepidoptera-lymantriidae
#9
JOURNAL ARTICLE
Songkai Liao, Haoyu Lin, Jiajin Wang, Qi Wang, Hongjian Wei, Hui Chen
Perina nuda (Lepidoptera: Lymantriidae) is a serious pest of banyan trees (Ficus spp.), which is distributed in South China, but little is known about the host preference on the different banyan tree species. To address this gap, we conducted experiments to investigate larval feeding preferences, assessing the impact of feeding experience in both choice and no-choice conditions. Fifth and sixth instars were exposed to 4 banyan species, and food intake, feeding area, and relative ingestion index were measured...
December 20, 2023: Journal of Economic Entomology
https://read.qxmd.com/read/38072554/alteration-of-redox-status-and-fatty-acid-profile-in-gills-from-the-green-crab-carcinus-aestuarii-following-dimethoate-exposure
#10
JOURNAL ARTICLE
Dalya Belhassen, Safa Bejaoui, Roberto Martins, Fernando Perina, Joana Figueiredo, Boutheina Ben Abdallah, Zeineb Khila, Samir Boubaker, Chayma Ben Fayala, Monia Trabelsi, Nejla Soudani
Dimethoate is a broad-spectrum organophosphate insecticide and acaricide. Through various pathways, such as runoff and drift, dimethoate can reach marine environment, and easily impact common organisms in coastal areas, close to agriculture lands, namely crustaceans. The purpose of this study was to investigate the potential effects of dimethoate exposure (50, 100, and 200 μg/l), for 1 day, on a wide range of markers of oxidative stress and neurotransmission impairment, as well as fatty acids composition and histopathological aspect in the gills of the green crab Carcinus aestuarii...
December 2023: Pesticide Biochemistry and Physiology
https://read.qxmd.com/read/38052132/could-assisted-reproductive-techniques-affect-equine-fetal-membranes-and-neonatal-outcome
#11
JOURNAL ARTICLE
Aliai Lanci, Francesca Perina, Sabrina Armani, Barbara Merlo, Eleonora Iacono, Carolina Castagnetti, Jole Mariella
Embryo transfer (ET) and intracytoplasmic sperm injection (ICSI) are widely used in equine species, but their effects on fetal adnexa and neonates have not been investigated yet. The aim of this study was to retrospectively evaluate whether pregnancies obtained by ET or ICSI could be associated with the presence of macroscopic alterations of fetal membranes (FM) and umbilical cord (UC) and if the use of these techniques could influence neonatal outcome. Sixty-six light breed mares hospitalized at the Veterinary Teaching Hospital, University of Bologna, for attending delivery were included in the study...
December 3, 2023: Theriogenology
https://read.qxmd.com/read/38044216/update-on-focal-infection-management-a-czech-interdisciplinary-consensus
#12
JOURNAL ARTICLE
Vojtěch Peřina, Roman Šmucler, Petr Němec, Vladislav Barták
BACKGROUND: The focal infection theory has been used to explain several chronic systemic diseases in the past. Systemic diseases were thought to be caused by focal infections, such as caries and periodontal diseases, and dentists were held responsible for these diseases due to the spread of oral infections. As knowledge of the interrelationship between oral microorganisms and the host immune response has evolved over the last few decades, the focal infection theory has been modified in various ways...
December 2, 2023: International Dental Journal
https://read.qxmd.com/read/37923285/photodynamic-inactivation-by-hypericin-p123-on-azole-resistant-isolates-of-the-trichophyton-rubrum-complex-as-planktonic-cells-and-biofilm
#13
JOURNAL ARTICLE
Juliana Aparecida Fernandes, Pollyanna Cristina Vicenzi Conrado, Brenda Serenini Perina, Ana Carolina Vieira de Oliveira, Glaucia Sayuri Arita, Isis Regina Grenier Capoci, Renato Sonchini Gonçalves, Wilker Caetano, Terezinha Inez Estivalet Svidzinski, Erika Seki Kioshima Cotica, Patrícia de Souza Bonfim-Mendonça
INTRODUCTION: The Trichophyton rubrum complex comprises the majority of dermatophyte fungi (DM) responsible for chronic cases of onychomycosis, which is treated with oral or topical antifungals. However, owing to antifungal resistance, alternative therapies, such as photodynamic therapy (PDT), are needed. This study investigated the frequency of the T. rubrum species complex in onychomycosis cases in the northwestern region of Paraná state, Brazil, and evaluated the efficacy of (PDT) using P123-encapsulated hypericin (Hyp-P123) on clinical isolates of T...
November 1, 2023: Photodiagnosis and Photodynamic Therapy
https://read.qxmd.com/read/37901443/standards-for-psychosocial-care-in-pediatric-cancer-adapted-proposal-for-latin-american-and-caribbean-countries
#14
JOURNAL ARTICLE
Viviana Trigoso, Liliana Vásquez, Soad Fuentes-Alabi, Claudia Pascual, Teresa Méndez, Essy Maradiegue, Mariela Villegas, Elisa Perina, Eugenia Ahumada, João de Bragança, Marcela Zubieta, María Del Pilar Jiménez, Hernan Bernedo, Lourdes Ruda, Melisa Sierralta, Alessandra Motta, Nuria Rossell, Daniela Vargas, Yurfa Salazar, Marisa López, Oscar Plascencia, Armando Arita, Raquel Molinas, Carmen Salaverria, Oscar Velásquez, Cecilia Ugaz
OBJECTIVE: To highlight the objectives, achievements, challenges, and next steps for the World Health Organization's Global Initiative for Childhood Cancer (GICC) framework, a project designed to improve psychosocial care (PSC) in pediatric cancer centers across Latin America and the Caribbean (LAC). METHODS: The project was launched in Peru, the first GICC focal country, in November 2020. The diagnosis phase included a survey and a semistructured interview with health professionals to assess PSC practices in institutions, and a needs assessment survey for caregivers...
2023: Pan American Journal of Public Health
https://read.qxmd.com/read/37865660/combined-effect-of-the-pro-apoptotic-rhtrail-protein-and-hsv-1-virus-in-head-and-neck-cancer-cell-lines
#15
JOURNAL ARTICLE
Lucas Bravo Perina, Izabela Natalia Faria Gomes, Ana Rúbia Alcantara Pelloso, Viviane Aline Oliveira Silva, Lidia Maria Rebolho Batista Arantes, Matias Eliseo Melendez
Knowledge on the molecular and clinical characteristics of head and neck squamous cell carcinoma (HNSCC) is vast. However, an effective therapy that increases the life expectancy of these patients, with a 5-year overall survival of 50%, is still unknown. Here we evaluated the combined effect of the pro-apoptotic protein rhTRAIL with the replication-competent wild-type HSV-1 virus in head and neck cancer cell lines. We observed a difference in the modulation profile of proteins related to apoptotic pathways in the studied cell lines...
October 21, 2023: Scientific Reports
https://read.qxmd.com/read/37827817/successful-treatment-of-sapho-syndrome-chronic-nonbacterial-osteomyelitis-and-acne-with-anakinra-and-denosumab-case-report-and-review-of-therapy
#16
JOURNAL ARTICLE
Zdeněk Adam, Anna Šedivá, David Zeman, Zdeněk Fojtík, Hana Petrášová, Jana Diatková, Miroslav Tomíška, Zdeněk Král, Jana Treglerová, Vojtěch Peřina, Kateřina Kamaradová, Zdenka Adamová, Luděk Pour
SAPHO is an acronym derived from capital letters of Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO). SAPHO syndrome is an umbrella term covering a constellation of bone lesions and skin manifestations. A 40-year-old male complained about his jaw and back pain, swelling of multiple joints and weight loss accompanied by physical deterioration and acne type skin lesions. Laboratory tests revealed abnormal elevation of inflammatory markers. Imaging studies illustrated multiple osteolytic bone lesions and paraosseal infiltrates...
2023: Vnitr̆ní Lékar̆ství
https://read.qxmd.com/read/37803166/author-correction-the-effect-of-thermal-photons-on-exceptional-points-in-coupled-resonators
#17
Grzegorz Chimczak, Anna Kowalewska-Kudłaszyk, Ewelina Lange, Karol Bartkiewicz, Jan Peřina
No abstract text is available yet for this article.
October 6, 2023: Scientific Reports
https://read.qxmd.com/read/37567909/comparison-of-covid-19-epidemic-among-czech-dentists-and-the-czech-general-population
#18
JOURNAL ARTICLE
Jan Schmidt, Vojtech Perina, Jakub Suchanek, Jana Treglerova, Nela Pilbauerova, Ondrej Sanca, Jan Muzik, Roman Smucler
Dentists are one of the professional groups most at risk for COVID-19 infection. Enhanced protective measures in dentistry have been adopted worldwide; however, it is unclear to what extent they were sufficient. To assess whether the protective measures outweighed the high infection risk, we compared COVID-19-related data between Czech dentists and the general Czech population. The data was obtained through a survey study attended by 15.8% of Czech Dental Chamber members. Data of the general population were acquired from the Czech Ministry of Health database...
August 11, 2023: Scientific Reports
https://read.qxmd.com/read/37545665/increased-grey-wolf-diurnality-in-southern-europe-under-human-restricted-conditions
#19
JOURNAL ARTICLE
Alejandro Martínez-Abraín, Ánxela Llinares, Luis Llaneza, Pilar Santidrián Tomillo, Juan Pita-Romero, Ramón J Valle-García, Victoria Formoso-Freire, Alejandra Perina, Daniel Oro
Wolves have been the archetype of wildlife persecution by humans for centuries all over the world, and still are heavily persecuted in some regions. Facultative diurnal/nocturnal wild mammals are known to become more nocturnal when persecuted. Conversely, little is known regarding the possibility of wolves becoming more diurnal if not persecuted. We took advantage of a 9-year natural experiment of restricted human access to a restored coal mine debris dump to study the daily activity patterns of wolves under conditions of infrequent human presence...
August 1, 2023: Journal of Mammalogy
https://read.qxmd.com/read/37426744/a-longitudinal-study-on-the-effects-of-parasocial-relationships-and-breakups-with-characters-of-a-health-related-tv-show-on-self-efficacy-and-exercise-behavior-the-case-of-the-biggest-loser
#20
JOURNAL ARTICLE
Perina Siegenthaler, Tanja Aegerter, Andreas Fahr
Overweight is one of the major health-related challenges in industrialized countries and mostly preventable through a healthy diet and regular engagement in physical activity. Health communication practitioners and researchers, therefore, started using the media's persuasive potential by creating entertainment-education (E-E) programs that promote healthy nutrition and exercise. By observing the characters in E-E programs, audience members can learn vicariously and eventually develop personal bonds with them...
August 2023: Communication & sport
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