keyword
https://read.qxmd.com/read/38644337/novel-rp-hplc-method-for-estimation-of-a-newly-developed-combination-of-tizanidine-and-etoricoxib-in-rat-plasma-eight-criteria-for-greens-evaluation
#1
JOURNAL ARTICLE
Eman A Assirey, Hoda A Ahmed, Rawan Al-Faze, M S Amin, Samar M Mahgoub, Fatma I Abo El-Ela, Mahmoud A Mohamed
A novel environmentally friendly reversed-phase high-performance liquid chromatography (RP-HPLC) method has been effectively validated for simultaneously measuring a prospective conjunction of tizanidine (TIZ) and etoricoxib (ETC), the combined medicine, in rat plasma. The technique employs diclofenac potassium as the internal standard, guaranteeing dependable and precise outcomes. This study aimed to assess the impact of the suggested combination therapy on treating inflammation resulting from rheumatoid arthritis (RA) in a rat model...
April 21, 2024: Archiv der Pharmazie
https://read.qxmd.com/read/38642791/ageing-influences-the-toxicity-of-two-innovative-nanofertilizers-to-the-soil-invertebrates-enchytraeus-crypticus-and-folsomia-candida
#2
JOURNAL ARTICLE
C Malheiro, M Prodana, D N Cardoso, R G Morgado, S Loureiro
The increasing global food demand is threatening the sustainability of agrifood production systems. The intensification of agricultural practices, with inadequate use of pesticides and fertilizers, poses major challenges to the good functioning of agroecosystems and drastically degrades the soil quality. Nanotechnology is expected to optimize the current farming practices and mitigate some associated impacts. Layered double hydroxides (LDHs) are a class of nanomaterials with high potential for use in agricultural productions, mostly due to their sustained release of nutrients...
April 18, 2024: Environmental Pollution
https://read.qxmd.com/read/38636206/ovulatory-cycle-shifts-in-human-motivational-prioritisation-of-sex-and-food
#3
JOURNAL ARTICLE
Lara Schleifenbaum, Julia Stern, Julie C Driebe, Larissa L Wieczorek, Tanja M Gerlach, Ruben C Arslan, Lars Penke
Previous research on the endogenous effects of ovarian hormones on motivational states in women has focused on sexual motivation. The Motivational Priority Shifts Hypothesis has a broader scope. It predicts a shift from somatic to reproductive motivation when fertile. In a highly powered preregistered online diary study across 40 days, we tested whether 390 women report such an ovulatory shift in sexual and eating motivation and behaviour. We compared 209 naturally cycling women to 181 women taking hormonal contraceptives (HC) to rule out non-ovulatory changes across the cycle as confounders...
April 17, 2024: Hormones and Behavior
https://read.qxmd.com/read/38635299/avoidant-restrictive-food-intake-disorder-symptoms-are-not-as-frequent-as-other-eating-disorder-symptoms-when-ulcerative-colitis-is-in-remission
#4
JOURNAL ARTICLE
Helen Burton-Murray, Katheryn Kiser, Jenny Gurung, Katherine Williams, Jennifer J Thomas, Hamed Khalili
BACKGROUND AND AIM: Recent studies have shown that up to 53% of patients with inflammatory bowel disease (IBD) screen positive for avoidant/restrictive food intake disorder (ARFID). There is however concern that ARFID screening rates are over-inflated in patients with active disease. We aimed to evaluate the frequency and characteristics of ARFID symptoms using the Nine Item ARFID Screen (NIAS), and to use another eating disorder measure, the Eating Disorder Examination-Questionnaire 8 (EDE-Q8), to rule-out/characterize other eating disorder cognitive and behavioral symptoms...
April 18, 2024: Journal of Crohn's & Colitis
https://read.qxmd.com/read/38629585/prediction-of-mass-spectrometry-ionization-efficiency-based-on-cosmo-rs-and-machine-learning-algorithms
#5
JOURNAL ARTICLE
Cheng-Zhen Nie, Hao Liu, Xu-Hui Huang, Da-Yong Zhou, Xu-Song Wang, Lei Qin
Non-targeted analysis of high-resolution mass spectrometry (MS) can identify thousands of compounds, which also gives a huge challenge to their quantification. The aim of this study is to investigate the impact of mass spectrometry ionization efficiency on various compounds in food at different solvent ratios and to develop a predictive model for mass spectrometry ionization efficiency to enable non-targeted quantitative prediction of unknown compounds. This study covered 70 compounds in 14 different mobile phase ratio environments in positive ion mode to analyze the rules of the matrix effect...
April 17, 2024: Analyst
https://read.qxmd.com/read/38618852/inhibitors-and-supporters-of-policy-change-in-the-regulation-of-unhealthy-food-marketing-in-australia
#6
JOURNAL ARTICLE
Yandisa Ngqangashe, Sirinya Phulkerd, Ashley Schram, Jeff Collin, Carmen Huckel Schneider, Anne Marie Thow, Sharon Friel
BACKGROUND: Evidence on the impact of policies that regulate unhealthy food marketing demonstrates a need for a shift from pure industry self-regulation toward statutory regulation. Institutional rules, decision-making procedures, actor practices and institutional norms influence the regulatory choices made by policymakers. This study examined institutional processes that sustain, support, or inhibit change in the food marketing regulation in Australia using the three pillars of institutions framework - regulatory, normative and cultural cognitive pillars...
February 13, 2024: International Journal of Health Policy and Management
https://read.qxmd.com/read/38613923/fostering-wellbeing-and-healthy-lifestyles-through-conviviality-and-commensality-underappreciated-benefits-of-the-mediterranean-diet
#7
REVIEW
Elisabetta Bernardi, Francesco Visioli
Among the often-neglected features of healthy diets, such as the Mediterranean diet, is the preparation and sharing of food, which is (or was) done in a social environment governed by social rules rather than by time constraints. The act of eating is a daily human practice that is not limited to meeting nutritional and energy needs but also involves a constructed social dimension of sharing meals that is part of the process of human civilization and food cultures around the world. In this narrative review, we outline the importance of conviviality in steering part of the health effects of healthful diets, with special reference to the Mediterranean diet...
March 21, 2024: Nutrition Research
https://read.qxmd.com/read/38613044/impact-of-melatonin-supplementation-on-sports-performance-and-circulating-biomarkers-in-highly-trained-athletes-a-systematic-review-of-randomized-controlled-trials
#8
REVIEW
Ana M Celorrio San Miguel, Enrique Roche, María Herranz-López, Marta Celorrio San Miguel, Juan Mielgo-Ayuso, Diego Fernández-Lázaro
Melatonin (N-acetyl-5 methoxytryptamine) is an indolic neurohormone that modulates a variety of physiological functions due to its antioxidant, anti-inflammatory, and immunoregulatory properties. Therefore, the purpose of this study was to critically review the effects of melatonin supplementation in sports performance and circulating biomarkers related to the health status of highly trained athletes. Data were obtained by performing searches in the following three bibliography databases: Web of Science, PubMed, and Scopus...
March 30, 2024: Nutrients
https://read.qxmd.com/read/38612737/diversity-complexity-and-specificity-of-bacterial-lipopolysaccharide-lps-structures-impacting-their-detection-and-quantification
#9
JOURNAL ARTICLE
Flavien Dardelle, Capucine Phelip, Maryam Darabi, Tatiana Kondakova, Xavier Warnet, Edyta Combret, Eugenie Juranville, Alexey Novikov, Jerome Kerzerho, Martine Caroff
Endotoxins are toxic lipopolysaccharides (LPSs), extending from the outer membrane of Gram-negative bacteria and notorious for their toxicity and deleterious effects. The comparison of different LPSs, isolated from various Gram-negative bacteria, shows a global similar architecture corresponding to a glycolipid lipid A moiety, a core oligosaccharide, and outermost long O-chain polysaccharides with molecular weights from 2 to 20 kDa. LPSs display high diversity and specificity among genera and species, and each bacterium contains a unique set of LPS structures, constituting its protective external barrier...
March 31, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38593553/widely-targeted-metabolomics-based-analysis-of-the-impact-of-l-plantarum-and-l-paracasei-fermentation-on-rosa-roxburghii-tratt-juice
#10
JOURNAL ARTICLE
You Luo, Ruling Tang, Han Qiu, Angxin Song
Rosa roxburghii Tratt fruits (RRT) exhibit extremely high nutritional and medicinal properties due to its unique phytochemical composition. Probiotic fermentation is a common method of processing fruits. Variations in the non-volatile metabolites and bioactivities of RRT juice caused by different lactobacilli are not well understood. Therefore, we aimed to profile the non-volatile components and investigate the impact of L. plantarum fermentation (LP) and L. paracasei fermentation (LC) on RRT juice (the control, CG)...
March 27, 2024: International Journal of Food Microbiology
https://read.qxmd.com/read/38587606/neophobia-sensory-experience-and-child-s-schemata-contribute-to-food-choices
#11
REVIEW
Viviana Finistrella, Nicoletta Gianni, Danilo Fintini, Deny Menghini, Silvia Amendola, Lorenzo Maria Donini, Melania Manco
PURPOSE: The aim of the present review is to analyze dynamic interactions between nutrigenomics, environmental cues, and parental influence, which can all lead to children's neophobic reactions and its persistence in time. METHODS: We reviewed studies available on electronic databases, conducted on children aged from birth to 18 years. We also considered official websites of Italian Institutions, providing advice on healthy eating during infancy. RESULTS: Modern day societies are faced with an eating paradox, which has severe and ever-growing implications for health...
April 8, 2024: Eating and Weight Disorders: EWD
https://read.qxmd.com/read/38585216/assessment-of-the-feed-additive-consisting-of-patent-blue-v-for-all-non-food-producing-animal-species-for-the-renewal-of-its-authorisation-versele-laga-nv
#12
JOURNAL ARTICLE
Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Maryline Kouba, Marta López-Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Gabriele Aquilina, Jaume Galobart, Orsolya Holczknecht, Paola Manini, Maria Vittoria Vettori, Fabiola Pizzo
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of Patent Blue V as a sensory feed additive for non-food-producing animals. The additive is already authorised for use with non-food-producing animals. The applicant has not provided evidence that the additive currently on the market complies with the existing conditions of authorisation. The FEEDAP Panel cannot conclude whether the additive remains safe for the target species due to the non-compliance with the specifications and the lack of adequate data on the potential aneugenicity of the additive...
April 2024: EFSA journal
https://read.qxmd.com/read/38582899/chronic-stridor-in-a-toddler-after-ingestion-of-a-discharged-button-battery-a-case-report
#13
JOURNAL ARTICLE
Zoe S Oftring, Doortje M Mehrtens, Julian Mollin, Eckard Hamelmann, Sebastian Gaus
BACKGROUND: Button battery (BB) ingestions (BBI) are increasingly prevalent in children and constitute a significant, potentially life-threatening health hazard, and thus a pediatric emergency. Ingested BBs are usually charged and can cause severe symptom within 2 h. Discharged BBs ingestion is very rare and protracted symptom trajectories complicate diagnosis. Timely imaging is all the more important. Discharged BBs pose specific hazards, such as impaction, and necessitate additional interventions...
April 6, 2024: BMC Pediatrics
https://read.qxmd.com/read/38582600/mixed-insect-pest-populations-of-diaspididae-species-under-control-of-oligonucleotide-insecticides-3-end-nucleotide-matters
#14
JOURNAL ARTICLE
Nikita V Gal'chinsky, Ekaterina V Yatskova, Ilya A Novikov, Alexander K Sharmagiy, Yuri V Plugatar, Vladimir V Oberemok
Diaspididae are one of the most serious small herbivorous insects with piercing-sucking mouth parts and are major economic pests as they attack and destroy perennial ornamentals and food crops. Chemical control is the primary management approach for armored scale infestation. However, chemical insecticides do not possess selectivity in action and not always effective enough for the control of armored scale insects. Our previous work showed that green oligonucleotide insecticides (olinscides) are highly effective against armored and soft scale insects...
March 2024: Pesticide Biochemistry and Physiology
https://read.qxmd.com/read/38582136/analysis-of-green-word-of-mouth-advertising-behavior-of-organic-food-consumers
#15
JOURNAL ARTICLE
Flavio Boccia, Amirhossein Tohidi
The word-of-mouth (WOM) marketing process is one of the main means by which consumers obtain information. As a communication channel between consumers in economically developing countries, WOM may contribute to the development of the organic food market. The primary objective of this study is to segment organic saffron consumers in Mashhad, Iran, and determine how they engage in WOM marketing. Data were collected through questionnaires from 13 districts of Mashhad using a stratified sampling method. In this study, 400 organic saffron consumers were grouped using a self-organizing map (SOM) neural network based on consumer neobehavioristic theory, and then, using decision trees, consumer behavior rules were extracted for participating in the WOM for each group...
April 4, 2024: Appetite
https://read.qxmd.com/read/38581789/long-range-infrared-absorption-spectroscopy-and-fast-mass-spectrometry-for-rapid-online-measurements-of-volatile-organic-compounds-from-black-tea-fermentation
#16
JOURNAL ARTICLE
Chongshan Yang, Leizi Jiao, Chunwang Dong, Xuelin Wen, Peng Lin, Dandan Duan, Guanglin Li, Chunjiang Zhao, Xinglan Fu, Daming Dong
Fermentation is the key process to determine the quality of black tea. Traditional physical and chemical analyses are time consuming, it cannot meet the needs of online monitoring. The existing rapid testing techniques cannot determine the specific volatile organic compounds (VOCs) produced at different stages of fermentation, resulting in poor model transferability; therefore, the current degree of black tea fermentation mainly relies on the sensory judgment of tea makers. This study used proton transfer reaction mass spectrometry (PTR-MS) and fourier transform infrared spectroscopy (FTIR) combined with different injection methods to collect VOCs of the samples, the rule of change of specific VOCs was clarified, and the extreme learning machine (ELM) model was established after principal component analysis (PCA), the prediction accuracy reached 95% and 100%, respectively...
April 2, 2024: Food Chemistry
https://read.qxmd.com/read/38571619/antioxidant-activity-metabolic-profiling-in-silico-molecular-docking-and-admet-analysis-of-nano-selenium-treated-sesame-seed-bioactive-compounds-as-potential-novel-drug-targets-against-cardiovascular-disease-related-receptors
#17
JOURNAL ARTICLE
Ilyas Ahmad, Zia-Ur-Rehman Mashwani, Zohaib Younas, Tayyaba Yousaf, Ajaz Ahmad, Carmen Vladulescu
Sesame ( Sesamum indicum ) is abundant in a diverse range of lignans, including sesamin, and γ-tocopherol, constituting a cluster of bioactive phenolic compound used for food and medicinal purposes. Cardiovascular diseases remain a leading global health challenge, demanding vigilant prevention and innovative treatments. This study was carried out to evaluate the effect of plant mediated SeNPs on sesame metabolic profile and to screen and check the effect bioactive compounds against CVD via molecular drug docking technique...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38556307/-standardization-and-practical-application-of-quantitative-nmr-qnmr
#18
JOURNAL ARTICLE
Naoki Sugimoto
In Japan, quantitative NMR (qNMR) has already been recognized as a standard method for determining the purity of quantitative samples not only in the Japanese Pharmacopoeia and the Japanese Standards and Specifications for Food Additives but also in the Japanese Industrial Standard (JIS K 0138: 2018). However, since there was no consensus on the establishment of a standard method, the international standardization of qNMR was initiated based on a proposal from Japan. After three years of discussion among experts, International Organization for Standardization/Technical Committee on Food (ISO/TC34) published ISO 24583: 2022 "Quantitative nuclear magnetic resonance spectroscopy-Purity determination of organic compounds used for foods and food products-General requirements for 1 H-NMR internal standard method...
2024: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://read.qxmd.com/read/38555615/-features-of-the-eating-behavior-of-patients-who-consider-themselves-healthy
#19
JOURNAL ARTICLE
I A Krylova
Non-communicable diseases have become one of the causes of premature mortality among the able-bodied population. The risk factors these diseases are individual characteristics of the diet and nutritional regimen. Their timely detection and correction are necessary for the early diagnosis, treatment and prevention of chronic non-communicable diseases. The purpose of the study was to determine the features of the structure of the actual consumption of the main food groups and the eating behavior of outpatients who are subject to periodic medical examinations and consider themselves healthy...
2024: Voprosy Pitaniia
https://read.qxmd.com/read/38547775/progression-free-survival-estimates-are-shaped-by-specific-censoring-rules-implications-for-pfs-as-an-endpoint-in-cancer-randomized-trials
#20
JOURNAL ARTICLE
Vadim Lesan, Timothée Olivier, Vinay Prasad
Kaplan-Meier analysis hinges on the assumption that patients who are censored- lost to follow-up, or only recently enrolled on the study- are no different, on average, than patients who are followed. As such, censoring these patients- omitting their future information and taking the average of those who were followed- should not dramatically change the overall estimate. Yet, in a recent clinical trial, two sets of censoring rules- one favored by trialists and one favored by the US Food and Drug Administration- were applied to a progression-free survival (PFS) estimate...
March 20, 2024: European Journal of Cancer
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