keyword
https://read.qxmd.com/read/36619268/a-population-based-cross-sectional-study-on-the-prevalence-and-associated-risk-factors-of-helicobacter-pylori-infection-in-rafsanjan-a-low-gastric-cancer-area-in-southeast-iran
#21
JOURNAL ARTICLE
Alireza Sadjadi, Elham Akbarpour, Masoomeh Alimohammadian, Sahar Masoudi, Reza Ghanbari, Zohreh Rajabi Pour, Faegheh Mohmmad Akbari, Minal Dafeh Jafari, Akbar Feiz-Sani, Hamid Hakimi, Farideh Siavooshi, Sadegh Massarrat, Reza Malekzadeh
Background : Despite all improvements in sanitation and exposure to antibiotics over time, Helicobacter pylori (HP) prevalence remains high, affecting the lives of about half of the world population, which can gradually lead to serious upper gastrointestinal disorders. Understanding HP's epidemiologic patterns help us to better manage the burden of this infection and to plan more effectively regarding potential screening or eradication strategies. We, therefore, aimed to report the crude and age- and sex-standardized prevalence rate of HP infection, its trend, and possible associated factors among asymptomatic healthy individuals in Rafsanjan city, a low-incidence area of gastric cancer (GC) in the southeast of Iran, from July 2018 to December 2021...
July 2022: Middle East Journal of Digestive Diseases
https://read.qxmd.com/read/36561269/the-effect-of-helicobacter-pylori-infection-on-overweight-a-systematic-review-and-meta-analysis
#22
REVIEW
Farideh Kamarehei, Younes Mohammadi
BACKGROUND: The association between Helicobacter pylori infection and overweight, as one of the most common health issues, remains controversial. In this study, we systematically reviewed the effect of H. pylori infection and overweight to get a reliable answer. METHODS: We used the Preferred Reporting Items for the Systematic Review and Meta-Analysis statement. We searched the association between H. pylori and overweight infection in international databases including Medline, Web of knowledge and Scopus, without any limitations of language, publication type, and publication status in search step of this systematic review from 2000 to 2020...
November 2022: Iranian Journal of Public Health
https://read.qxmd.com/read/36482315/effect-of-helicobacter-pylori-eradication-on-metabolic-profile-an-international-multicenter-case-control-study
#23
MULTICENTER STUDY
Pezhman Alavinejad, Eskandar Hajiani, Abazar Parsi, Azam Satari, Mohammad Javad Rezaei, Morteza Nayebi, Ahmad Hormati, Omid Eslami, Mohammed Hussien Ahmed, Quang Trung Tran, Masoud Arshadzadeh, Siamak Baghaei, Samira Mohammadi, Seyed Jalal Hashemi, Alireza Sedaghat
BACKGROUND: As a gram-negative and microaerophilic bacterium, Helicobacter pylori (HP) is the main cause of chronic gastritis. Therefore, considering the high prevalence of HP infection worldwide, as well as the increasing prevalence of metabolic disorders, the present study aimed to investigate the relationship between HP infection eradication and metabolic profile. METHODS: This prospective case-control study was performed on patients with HP infection whom referred to 7 medical centers in 3 countries (Iran, Egypt, and Vietnam) in 2020-2021...
December 8, 2022: BMC Gastroenterology
https://read.qxmd.com/read/36419946/association-of-d299g-polymorphism-of-tlr4-gene-and-caga-virulence-factor-of-h-pylori-among-the-iranian-patients-with-colorectal-cancer
#24
JOURNAL ARTICLE
Sama Malallah Ghayemi, Nahid Aboutaleb, Ghazal Yousefi, Neda Mousavi-Niri, Maryam Naseroleslami
Background: Colorectal cancer (CRC) represents 9% of all malignancies globally. TLR4 gene defenses against Helicobacter pylori infection (HPI), so its mutations are a risk factor for CRC. As there is a correlation between (HPI) and gastric cancer, we investigated whether there is an association between CagA virulence factor in HPI and D299G polymorphism of TLR4 gene with developing CRC among Iranians. Methods: This retrospective study included 85 biopsies of confirmed colorectal lesions out of 230 subjects, which were divided into two age groups...
2022: Medical Journal of the Islamic Republic of Iran
https://read.qxmd.com/read/36393826/epiya-motif-genetic-characterization-from-helicobacter-pylori-isolates-in-distinct-geographical-regions-of-iran
#25
JOURNAL ARTICLE
Fatemeh Estaji, Bahram Nasr Esfahani, Saeed Zibaee, Mohammad Hossein Sanei, Sharareh Moghim
Background: This study aimed to determine the current EPIYA motifs of the cag A gene in Helicobacter pylori isolates from patients with gastric disorders, and evaluate the association between these patterns and the clinical outcome of H. pylori infection in different geographical regions of Iran. Materials and Methods: We examined 150 patients with gastrointestinal disorders from the central and eastern regions of Iran. The detection of H. pylori and screening of cag A was performed by polymerase chain reaction (PCR)...
2022: Advanced Biomedical Research
https://read.qxmd.com/read/36317032/which-individuals-with-positive-family-history-of-gastric-cancer-urgently-need-intensive-screening-and-eradication-of-helicobacter-pylori-a-systematic-review-and-meta-analysis
#26
REVIEW
Gui He, Xuanke Ji, Yali Yan, Kunyan Wang, Chunhua Song, Peng Wang, Hua Ye, Liping Dai, Jianying Zhang, Kaijuan Wang
Background: Family history may inform individuals that they are at risk of gastric cancer (GC). However, it is too extensive to conduct intensive screening strategies for all individuals with family history of GC instead of average-risk screening. To establish more precise prevention strategies, accurate risk estimates are necessary for individuals with family history of GC. Methods: We searched PubMed, EMBASE and Cochrane for all relevant studies from their inception to May 21, 2020, for cohort and case-control studies investigating the association between family history of GC and its risk...
December 2021: Iranian Journal of Public Health
https://read.qxmd.com/read/36249096/combination-of-serum-test-and-questionnaire-in-early-gastric-cancer-screening
#27
JOURNAL ARTICLE
Qiang Li, Yibing Liu, Zhe Meng, Qingfeng Ge, Liyan Zhao, Huiying Chu, Xiaomin Li, Jingli Chen, Qingju Meng
Background: We aimed to analyze the predictive role of serum test and questionnaire in Early Gastric Cancer in The First Affiliated Hospital of Xingtai Medical College, Hebei Province from 2019 to 2020. Methods: In this prospective study, 280 medical examiners underwent questionnaire, serum test and gastroscopy. They were divided into Gastric cancer (GC) and Non-Gastric cancer (NGC) group. NGC group was divided into Low-grade intraepithelial neoplasia (LGIN), Chronic atrophic gastritis (CAG) and Non-chronic atrophic gastritis (NCAG) group...
August 2022: Iranian Journal of Public Health
https://read.qxmd.com/read/36147796/dnmt1-gene-expression-in-patients-with-helicobacter-pylori-infection
#28
JOURNAL ARTICLE
Manouchehr Ahmadi Hedayati, Amjad Ahmadi, Zahed Khatooni
DNMT1, as a critical enzyme affecting epigenetics through methylation of DNA cytosine-rich sequences, regulates gene expression. Exterior factors including long-term infections, in this study Helicobacter pylori infection, could change host cells' epigenetics by affecting DNMT1 gene expression. This study investigated the statistical correlation between H. pylori virulence genes and DNMT1 gene expression in gastric antral epithelial cells of gastric adenocarcinoma and gastritis patients. In a case-control study, 50 and 53 gastritis and gastric adenocarcinoma antral biopsies, including 23 and 21 patients with H...
2022: TheScientificWorldJournal
https://read.qxmd.com/read/36130718/association-of-hypercholesterolemia-with-gastric-intestinal-metaplasia-findings-after-sleeve-gastrectomy-pathology-review
#29
JOURNAL ARTICLE
Mohammad Kermansaravi, Masoud Rezvani, Farid Elmi Sadr, Rohollad Valizadeh, Ali Kabir, Abdolreza Pazouki
BACKGROUND: We evaluated the relationship between comorbidities associated with obesity, body mass index (BMI), and development of intestinal metaplasia (IM) after vertical sleeve gastrectomy (VSG). MATERIALS AND METHODS: All VSG specimens performed at an academic center between 2011 and 2018 were reviewed. All specimens underwent histopathologic assessment, while those with findings suspicious for IM underwent additional immunohistochemical work up. Baseline patient characteristics and demographic data were obtained from Iran National Obesity Surgery Database by retrospective review...
September 5, 2022: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://read.qxmd.com/read/36033661/labdane-type-diterpenes-from-pinus-eldarica-needles-and-their-anti-helicobacter-pylori-activity
#30
JOURNAL ARTICLE
Se Yun Jeong, Myung Woo Na, Eon Chung Park, Jin-Chul Kim, Dong-Min Kang, Hamed Hamishehkar, Mi-Jeong Ahn, Jung Kyu Kim, Ki Hyun Kim
Pinus eldarica is a medicinal tree used in traditional herbal medicine for the treatment of bronchial asthma and various skin diseases. As part of our ongoing search for bioactive phytochemicals with novel structures in natural products, we performed a phytochemical analysis of the methanol (MeOH) extract from P. eldarica needles collected in Iran. Phytochemical investigation of the MeOH extract, aided by liquid chromatography-mass spectrometry-based analysis, resulted in the isolation and identification of three labdane-type diterpenes ( 1-3 ), including a new and relatively unique norlabdane-type diterpene with a peroxide moiety, eldaricoxide A ( 1 )...
August 23, 2022: ACS Omega
https://read.qxmd.com/read/35968205/antibiotic-resistance-pattern-of-helicobacter-pylori-strains-isolated-from-patients-in-isfahan-iran
#31
JOURNAL ARTICLE
Hajarsadat Sadeghi, Tahmineh Narimani, Elham Tabesh, Fatemeh Shafiee, Rasool Soltani
Background: The objective of this study was to evaluate the antibiotic resistance pattern of Helicobacter pylori strains isolated from patients in Isfahan province. Materials and Methods: Gastric antrum biopsy specimens of patients undergoing endoscopy were cultured. The samples with the growth of H. pylori underwent antibiotic susceptibility test by disk diffusion method. Reaults: Of 96 samples, 50 samples (53%) were positive for H. pylori ...
2022: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://read.qxmd.com/read/35942998/a-comprehensive-survey-of-the-relationship-between-helicobacter-pylori-infection-and-atherosclerosis-in-the-iranian-population-a-systematic-review-and-meta-analysis
#32
JOURNAL ARTICLE
Masoud Keikha, Mohsen Karbalaei
BACKGROUND: Helicobacter pylori is a gram-negative, spiral-shaped, and microaerophilic bacterium that inhabits the human gastric mucosa and is considered to be the most important etiologic agent for gastrointestinal disorders. Recently, however, there is ample evidence to suggest an association between H. pylori infection and extragastric complications, particularly atherosclerosis. The aim of this study was to evaluate the rate of H. pylori infection and the risk of atherosclerosis in an Iranian population...
April 1, 2022: Archives of Iranian Medicine
https://read.qxmd.com/read/35919645/helicobacter-pylori-infection-among-iranian-patients-with-normal-upper-gastrointestinal-endoscopy
#33
JOURNAL ARTICLE
Hassan Salmanroghani, Mohammad Hassan Rouzegari, Roham Salmanroghani
Background: Helicobacter pylori infection can be a risk factor for non-cardia gastric cancer. In the present study, we aimed to assess the rate of Helicobacter pylori infection, its virulence factor and precancerous lesion among over 50 years old, dyspeptic patients with normal endoscopy. Methods: A total of 620 patients over 50 years of age with dyspepsia that referred to Shahid Sadoughi Hospital, Yazd, Iran from December 2018 to January 2019 were evaluated. One hundred fifty patients with normal appearance endoscopy were selected, and six gastric biopsy specimens were taken from each subject...
2022: Caspian Journal of Internal Medicine
https://read.qxmd.com/read/35911519/-helicobacter-pylori-infection-maybe-a-risk-factor-for-cardiac-syndrome-x
#34
Dong-Hong Zhang, Chen Yuan, Bei-Bei Wang, Xin-Jiang Dong, Shu-Ping Lv, Fei-Hong Li, Zhen-Xiu Hou, Xiao-Li Liu, Kang Chen
Purpose: Cardiac syndrome X (CSX) is a condition with normal coronary angiography but angina pectoris. Chronic inflammation caused by Helicobacter pylori ( H. pylori ) infection may play a pathogenic role in CSX. Therefore, we conducted a meta-analysis to explore the relationship between H. pylori infection and risk of CSX. Methods: A systematic search in the Web of Science, Medline, Embase and Chinese databases (CNKI and Wanfang) was conducted up to October 2021...
2022: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/35845306/the-efficacy-and-safety-of-furazolidone-bismuth-quadruple-therapy-for-helicobacter-pylori-eradication-with-or-without-probiotic-supplementation
#35
JOURNAL ARTICLE
Nafeh Noorbakhsh, Shahriar Nikpour, Mohammad Salehi
Aim: In this clinical trial we use furazolidone-bismuth quadruple therapy with or without probiotics for H.pylori eradication. Background: Increasing rates of eradication failure in H.pylori infection mainly due to antibiotic resistance has led to search for alternative regimens such as using novel antibiotics and/or using probiotic supplementation as conjunctive to the standard eradication regimens. Methods: This double blind clinical trial was performed in gastrointestinal clinic of Loghman Hakim University Hospital, Tehran, Iran...
2022: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/35772221/public-health-significance-of-helicobacter-pullorum-a-putative-food-associated-emerging-zoonotic-pathogen-in-iran
#36
REVIEW
Hosein Akhlaghi, Ashkan Jebelli Javan, Seyed Hesamodin Emadi Chashmi
According to the World Health Organization, diseases which are naturally transmissible from vertebrate animals to human beings or from humans to vertebrates are defined as the zoonotic diseases. Among the most common zoonotic pathogens, Helicobacter pullorum has earned public recognition regarding its public health significance. This Enterohepatic Helicobacter species has been shown to be a very dangerous and life-threatening microorganism, accounting for several clinically important infections in the human population...
June 26, 2022: Comparative Immunology, Microbiology and Infectious Diseases
https://read.qxmd.com/read/35618156/helicobacter-pylori-acquisition-rates-and-the-associated-risk-factors-amongst-newlywed-couples-a-prospective-cohort-study-in-tehran-iran
#37
JOURNAL ARTICLE
Maryam Hadji, Mahshid Mortazavi, Samaneh Saberi, Maryam Esmaieli, Neda Amini, Rahim Akrami, Rana Daroudian, Fatemeh Shakeri, Hossein Khedmat, Eero Pukkala, Marjan Mohammadi, Kazem Zendehdel
BACKGROUND: The rates and routes of Helicobacter pylori transmission, in a high prevalent country like Iran, with gastric cancer as the leading cause of male cancer mortality is of essence. Here, we have studied the H. pylori-associated risk factors and the likelihood of interspousal transmission. METHODS: In a cohort of 686 young prewed couples, questionnaires were self-administered and serum samples were collected, for assessment of risk factors and sero-status of H...
May 23, 2022: Microbes and Infection
https://read.qxmd.com/read/35611250/preoperative-esophagogastroduodenoscopy-findings-and-effects-on-laparoscopic-roux-en-y-gastric-bypass-in-area-with-high-prevalence-of-helicobacter-pylori-infection-multi-center-experience-in-iran
#38
JOURNAL ARTICLE
Mehdi Alimadadi, Seyedali Seyedmajidi, Sina Safamanesh, Elena Zanganeh, Seyed Ashkan Hosseini, Shahin Hajiebrahimi, Mohammadreza Seyyedmajidi
AIM: The current study aimed to evaluate EGD findings effects on laparoscopic Roux-en-Y gastric bypass (RYGB) plan and time in areas with a high prevalence of Helicobacter pylori infection. BACKGROUND: Esophagogastroduodenoscopy (EGD) and Helicobacter pylori testing are routine parts of preoperative assessment of bariatric surgery at many centers. METHODS: This was a crosssectional study of all patients underwent EGD and histopathological examination before laparoscopic RYGB in three gastroenterology centers in Iran between January 2018 and December 2020...
2022: Gastroenterology and Hepatology From Bed to Bench
https://read.qxmd.com/read/35592739/is-the-presence-of-helicobacter-pylori-in-the-colonic-mucosa-provocative-of-activity-in-ulcerative-colitis
#39
JOURNAL ARTICLE
Javad Ranjbar, Bita Geramizadeh, Kamran Bagheri Lankarani, Zahra Jowkar, Mitra Mirzai, Elham Moazamian
Background: Epidemiologic studies have shown world-wide increasing incidence of ulcerative colitis (UC) as an autoimmune disease of intestine. In the meantime, gastrointestinal H. Pylori infection is being decreased. Objectives: There are very few studies about comparing the presence of H. Pylori in the colon and the disease activity of UC. There is no study form Iran. In this study, we tried to investigate the presence of H. Pylori in the mucosa of colon by molecular and microbiological as well as pathological methods to find any association between the presence of this organism in the colon and the presence and activity of UC...
January 2022: Clinical pathology
https://read.qxmd.com/read/35534888/comparing-the-prevalence-of-helicobacter-pylori-and-virulence-factors-caga-vaca-and-dupa-in-supra-gingival-dental-plaques-of-children-with-and-without-dental-caries-a-case-control-study
#40
JOURNAL ARTICLE
Aida Mehdipour, Parisa Chaboki, Farzaneh Rasouli Asl, Mohammad Aghaali, Negar Sharifinejad, Saeed Shams
BACKGROUND: Helicobacter pylori infection is one of the most common infectious diseases in humans. Dental plaque is considered as a reservoir of this bacterium, which could play an important role in the development of gastrointestinal problems. Our aim was to investigate the prevalence of H. pylori and its virulence factors in dental plaques in children with and without dental caries. METHODS: Among children aged 6 to 12 years, a total of 72 children were enrolled in the study, including 36 cases with total DMFT/dmft > 3 (case group) and 36 participants with total DMFT/dmft < 1 (control group)...
May 9, 2022: BMC Oral Health
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