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NIRS anesthesia children

Alexander B Froyshteter, Dmitry Tumin, Emmett E Whitaker, David P Martin, Mumin Hakim, Hina Walia, Tarun Bhalla, Joseph D Tobias
Use of spinal anesthesia (SA) in children may address concerns about potential neurocognitive effects of general anesthesia. We used near-infrared spectroscopy (NIRS) to assess the effects of SA on cerebral and tissue oxygenation in 19 patients aged 7 ± 3 months. Prior to SA placement, NIRS monitors were placed on the forehead (cerebral) and the thigh (tissue). Intraoperative cerebral and tissue saturation were 73 ± 7 and 80 ± 11%, respectively, before SA placement. NIRS measurements were monitored every minute for 30 min after SA placement and modeled using mixed-effects linear regression...
April 2018: Journal of Anesthesia
Brian Schloss, Dmitry Tumin, Aymen Naguib, Julie Rice, Mark Galantowicz, Joseph D Tobias
Background: The aim of this study was to evaluate the response of the LiDCO-rapid™ during intraoperative phlebotomy in anesthetized children prior to surgery for congenital heart disease. Methods: After the induction of general anesthesia and endotracheal intubation, baseline vital signs were recorded, along with pulse pressure variability (PPV) and stroke volume variability (SVV) from the LiDCO-rapid™ and cerebral oxygenation (rSO2 ) using near-infrared spectroscopy (NIRS)...
December 2017: Cardiology Research
Thushara Perera, Philip M Lewis, Andrew J Davidson, Paul Junor, Stephen Bottrell
BACKGROUND: Anesthetic depth is an important parameter to monitor during surgery, yet remains difficult to quantify, particularly in young children where developmental changes influence the electroencephalogram. A more fundamental physiological response to stimulation is the increase in cerebral blood flow secondary to increased metabolic demand, referred to as flow-metabolism coupling (FMC) and measurable using near-infrared spectroscopy (NIRS). Little is known about the effect of anesthesia on FMC; therefore, we studied visually evoked hemodynamic responses (VEHRs) using NIRS in children undergoing general anesthesia for minor surgical procedures...
March 2015: Paediatric Anaesthesia
Thilo Fleck, Stephan Schubert, Peter Ewert, Brigitte Stiller, Nicole Nagdyman, Felix Berger
Propofol is a short-acting, intravenously administered hypnotic agent which is used in procedural sedation in children. Propofol is known to decrease systemic vascular resistance, arterial blood pressure and can lead to desaturations and decreased systemic perfusion in children with cardiac shunting. This may result in a reduction in cerebral blood flow and oxygenation. Near-infrared spectroscopy (NIRS) can monitor cerebral tissue oxygenation in the frontal neocortex. The objective of our study was to measure the changes in cerebral oxygen and blood supply after Propofol infusion in children with congenital heart disease...
March 2015: Pediatric Cardiology
Ossam Rhondali, Caroline André, Agnès Pouyau, Aurélie Mahr, Simon Juhel, Mathilde De Queiroz, Khalid Rhzioual-Berrada, Sylvain Mathews, Dominique Chassard
OBJECTIVE/AIM: To assess the impact of sevoflurane and anesthesia-induced hypotension on brain perfusion in children younger than 6 months. BACKGROUND: Safe lower limit of blood pressure during anesthesia in infant is unclear, and inadequate anesthesia can lead to hypotension, hypocapnia, and low cerebral perfusion. Insufficient cerebral perfusion in infant during anesthesia is an important factor of neurological morbidity. In two previous studies, we assessed the impact of sevoflurane anesthesia on cerebral blood flow (CBF) by transcranial Doppler (TCD) and on brain oxygenation by NIRS, in children ≤2 years...
February 2015: Paediatric Anaesthesia
Ossam Rhondali, Simon Juhel, Sylvain Mathews, Quentin Cellier, François-Pierrick Desgranges, Aurélie Mahr, Mathilde De Queiroz, Agnès Pouyau, Khalid Rhzioual-Berrada, Dominique Chassard
OBJECTIVE/AIM: To assess the impact of sevoflurane and anesthesia-induced hypotension on brain oxygenation in children younger than 2 years. BACKGROUND: Inhalational induction with sevoflurane is the most commonly used technique in young children. However, the effect of sevoflurane on cerebral perfusion has been only studied in adults and children older than 1 year. The purpose of this study was to assess the impact of sevoflurane anesthesia on brain oxygenation in neonates and infants, using near-infrared spectroscopy...
July 2014: Paediatric Anaesthesia
Jacob Bettesworth, Tarun Bhalla, N'Diris Barry, Joseph D Tobias
BACKGROUND: Adequate tissue oxygenation is required for effective white blood cell function and bactericidal activity. Decreased tissue oxygenation has been shown to be a risk factor for perioperative wound infections. Regional anesthetic techniques result in a functional sympathetic block and may increase tissue oxygenation. The purpose of the current study is to prospectively evaluate changes in tissue oxygenation using a non-invasive near-infrared spectroscopy (NIRS) device following caudal epidural block in infants and children...
November 2012: Paediatric Anaesthesia
Nicholette Kasman, Ken Brady
Reflectance near-infrared spectroscopy has been used to measure cortical tissue oximetry for more than 30 years. In that time, many centers have adopted the routine use of the cerebral oximeter for children having repair of congenital heart lesions, while some prominent academic centers have resisted routine use of these monitors citing lack of definitive evidence for outcome benefit. In this review, we provide an overview of the method used to measure cerebral oximetry, as well as validation and clinical outcome data that have accrued from the use of cerebral oximeters...
May 2011: Paediatric Anaesthesia
Thilo Fleck, Stefan Schubert, Matthias Redlin, Brigitte Stiller, Peter Ewert, Felix Berger, Nicole Nagdyman
BACKGROUND: The brain of children in the early period after repair of congenital heart defects with cardiopulmonary bypass (CPB) may be more vulnerable to hemodynamic changes because of impaired cerebral autoregulation. During postoperative testing of the external temporary safety pacer, we performed desynchronizing ventricular pacing (VVI) while monitoring cerebral oxygenation using near-infrared spectroscopy (NIRS). METHODS: We prospectively investigated 11 children (6 girls, 5 boys)...
June 2010: Paediatric Anaesthesia
L E Tsypin, G G Prokop'ev, V V Lazarev, V V Shchukin, T G Popova, V S Kochkin, T V Lin'kova, K P Chusov
The investigation evaluated the effect of various volatile anesthetics on cerebral blood volume and oxygen status in sick children at the stage of anesthesia induction. Ninety-two children were distributed into 3 groups: Groups 1 (n = 36) and 2 (n = 24) underwent stepwise induction with halothane and enflurane, respectively. Group 3 (n = 32) had vital capacity rapid inhalation induction with sevoflurane. Cerebral oximetry (NIRS method) was used to measure the content of hydroxyhemoglobin, deoxyhemoglobin, the total level of hemoglobin and to assess regional cerebral tissue saturation (rSO2)...
January 2007: Anesteziologiia i Reanimatologiia
Richard J Berens, Eckehard A Stuth, Frederick A Robertson, Robert D Jaquiss, George M Hoffman, Todd J Troshynski, Susan R Staudt, Joseph R Cava, James S Tweddell, S Bert Litwin
BACKGROUND: Near infrared spectroscopy (NIRS) measures regional tissue oxygenation continuously and noninvasively and may allow assessment of changes in regional perfusion in real time. METHODS: We used NIRS monitoring to track real-time changes in regional oxygenation (rSO2) above and below the aortic cross-clamp in patients undergoing aortic coarctation repair and routinely stored these data in an operative electronic data base. This allowed us to analyze the changes in rSO2 during aortic coarctation repair for three pediatric age groups (neonates, infants <1 year, and children >1 year)...
July 2006: Paediatric Anaesthesia
V A Mikhel'son, G G Prokop'ev, V V Lazarev
Near infrared spectroscopy (NIRS) was used for noninvasive measurement of oxyhemoglobin (O2Hb) and total hemoglobin (tHb) in cerebral tissue and for evaluating local hemoglobin saturation with oxygen (rSO2) and cytochrome oxidase (Cytaa3) redox status in 68 children (6-14 years) during intravenous induction anesthesia with various anesthetics. Monoanesthesia with ketamine essentially increased the level of tHb and rSO2 and decreased the oxidized Cytaa3 fraction. Combined induction with ketamine and midazolame and propofol induction did not cause notable changes in the values of cerebral oxymetry...
January 2001: Anesteziologiia i Reanimatologiia
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