A Ouraghi, S Nieuviarts, J L Mougenel, M Allez, M Barthet, F Carbonnel, J Cosnes, J P Gendre, B Flourié, J J Meurisse, P Quandalle, O Ernst, M Lemann, A Cortot, R Modigliani, J F Colombel
AIM OF THE STUDY: To retrospectively evaluate the efficacy, the duration of response, and the tolerance of Remicade in anoperineal Crohn's disease. METHODS: Fifty patients with severe symptomatic and refractory anoperineal Crohn's lesions (38 fistulae and 29 cavitating ulcers and superficial fissures) were treated with 3 intravenous infusions of Remicade (5 mg/kg) at weeks 0, 2 and 6. Efficacy was assessed using Allan's functional score and proctologic examination at 8 weeks (W8) and 24 weeks (W24) after the first infusion...
November 2001: Gastroentérologie Clinique et Biologique