keyword
https://read.qxmd.com/read/38583964/-polypharmacy-in-older-people
#1
JOURNAL ARTICLE
Taro Kojima
After the publication of the guidelines about the safe drug therapy for older people in 2015 by the Japan Geriatrics Society, the risk of polypharmacy has become popular. Older people are likely to have multimorbidity, resulting in the use of multiple drugs. This not only increases the frequency of side effects, but also increase confusion and difficulty in medication management and adherence. Polypharmacy is the problem related to these complicated drug therapies and will increase by age. It is necessary to review drugs and resolve polypharmacy without making comorbid conditions worth...
2024: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://read.qxmd.com/read/38565981/classification-system-for-primary-care-provider-econsults-about-medications-for-older-adults-with-frailty
#2
JOURNAL ARTICLE
T Schneider, B Farrell, S Karunananthan, A Afkham, E Keely, C Liddy, L M McCarthy
BACKGROUND: Providing primary care for people with frailty can be challenging due to an increased risk of adverse outcomes and use of potentially inappropriate medications which may exacerbate characteristics of frailty. eConsult is a service where primary care providers can receive timely specialist advice for their patients through a secure web-based application. We aimed to develop a classification system to characterize medication-focused eConsult questions for older adults with frailty and assess its usability...
April 2, 2024: BMC Prim Care
https://read.qxmd.com/read/38529017/tizanidine-advances-in-pharmacology-therapeutics-and-drug-formulations
#3
REVIEW
Ling-Ling Zhu, Yan-Hong Wang, Quan Zhou
BACKGROUND: Skeletal muscle relaxants (SMRs) are widely used in treating musculoskeletal conditions. All SMRs, with the exception of baclofen and tizanidine, are on the list of 2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults. In our geriatric practice, off-label use of tizanidine as preemptive analgesia drove us to find recent advances in its pharmacology and therapeutics. An update review of tizanidine was thus presented, aiming to bring the latest knowledge to clinicians and promote further research and practical exploration...
2024: Journal of Pain Research
https://read.qxmd.com/read/38483427/geriatric-emergency-medication-safety-recommendations-gems-rx-modified-delphi-development-of-a-high-risk-prescription-list-for-older-emergency-department-patients
#4
JOURNAL ARTICLE
Rachel M Skains, Jennifer L Koehl, Amer Aldeen, Christopher R Carpenter, Cameron J Gettel, Elizabeth M Goldberg, Ula Hwang, Keith E Kocher, Lauren T Southerland, Pawan Goyal, Carl T Berdahl, Arjun K Venkatesh, Michelle P Lin
STUDY OBJECTIVE: Half of emergency department (ED) patients aged 65 years and older are discharged with new prescriptions. Potentially inappropriate prescriptions contribute to adverse drug events. Our objective was to develop an evidence- and consensus-based list of high-risk prescriptions to avoid among older ED patients. METHODS: We performed a modified, 3-round Delphi process that included 10 ED physician experts in geriatrics or quality measurement and 1 pharmacist...
March 12, 2024: Annals of Emergency Medicine
https://read.qxmd.com/read/38408767/prevalence-of-potentially-inappropriate-medications-among-newly-treated-patients-with-type-2-diabetes-in-uk-primary-care
#5
JOURNAL ARTICLE
Maria Luisa Faquetti, Géraldine Frey, Dominik Stämpfli, Stefan Weiler, Andrea M Burden
AIMS: The aim of this study was to estimate the prevalence of potentially inappropriate prescriptions (PIPs) in patients starting their first noninsulin antidiabetic treatment (NIAD) using two explicit process measures of the appropriateness of prescribing in UK primary care, stratified by age and polypharmacy status. METHODS: A descriptive cohort study between 2016 and 2019 was conducted to assess PIPs in patients aged ≥45 years at the start of their first NIAD, stratified by age and polypharmacy status...
February 26, 2024: British Journal of Clinical Pharmacology
https://read.qxmd.com/read/38367544/potentially-inappropriate-medication-use-among-older-adults-with-lower-limb-loss
#6
JOURNAL ARTICLE
Samantha Jeanne Stauffer, Ryan Todd Pohlig, John Robert Horne, Frank Bernard Sarlo, Jaclyn Megan Sions
OBJECTIVE: The aim of this study was to evaluate the prevalence of, and explore factors related to, prescription of potentially inappropriate medications (PIMs) among older adults with lower-limb loss (LLL). METHODS: This was a secondary analysis of a cross-sectional dataset collected through an interdisciplinary limb loss clinic between September 2013 and November 2022. Self-report medication lists were reviewed during in-clinic face-to-face interviews and compared to the American Geriatrics Society Beers Criteria corresponding to the patient's evaluation year...
February 16, 2024: Geriatric Nursing
https://read.qxmd.com/read/38326897/prevalence-and-trend-of-central-nervous-system-active-medication-polypharmacy-among-us-commercially-insured-adults-with-vs-without-early-onset-dementia-a-multi-year-cross-sectional-study
#7
JOURNAL ARTICLE
Yu-Jung Jenny Wei, Nistha Shrestha, ChienWei Chiang, Steven T DeKosky
BACKGROUND: Limited data exist on the prevalence and trend of central nervous system (CNS)-active medication polypharmacy among adults with early-onset dementia (EOD) and whether these estimates differ for adults without EOD but with chronic pain, depression, or epilepsy, conditions managed by CNS-active medications. METHODS: A multi-year, cross-sectional study using 2012-2021 MarketScan Commercial Claims data was conducted among adults aged 30 to 64 years with EOD and those without EOD but having a diagnosis of chronic pain, depression, or epilepsy as comparison groups...
February 8, 2024: Alzheimer's Research & Therapy
https://read.qxmd.com/read/38319349/comparing-ags-beers-2019-stopp-version-2-and-eu-7-pim-list-in-portuguese-older-adults-in-primary-health-care
#8
JOURNAL ARTICLE
Daniela A Rodrigues, Maria Teresa Herdeiro, Ramona Mateos-Campos, Adolfo Figueiras, Fátima Roque
PURPOSE: This study aims to identify PIM prevalence in older adults according to the 2019 Beers criteria, Screening Tool of Older Person's Prescriptions version 2 (STOPP v2) criteria, and the Portuguese EU(7)-PIM list and also to analyze the concordance between these criteria. METHODS: A retrospective study was conducted among 1200 Portuguese older adults (≥ 65 years old), users of primary health care. Demographic, clinical, and pharmacological data were collected concerning the period between April 2021 and August 2022...
February 6, 2024: European Journal of Clinical Pharmacology
https://read.qxmd.com/read/38273186/are-lists-of-potentially-inappropriate-medications-associated-with-hospital-readmissions-a-systematic-review
#9
Camille Schwab, Alice Clementz, Agnès Dechartres, Christine Fernandez, Patrick Hindlet
BACKGROUND: Suboptimal prescribing, including the prescription of potentially inappropriate medications (PIM), is frequent in patients aged 65 years and older. PIMs are associated with adverse drug events, which may lead to hospital admissions and readmissions for the most serious cases. Several tools, known as lists of PIMs, can detect suboptimal prescription. OBJECTIVE: This systematic review aimed to identify which lists of PIMs are associated with hospital readmission of older patients...
January 25, 2024: Drugs & Aging
https://read.qxmd.com/read/38273076/prevalence-and-appropriateness-of-polypharmacy-in-older-adults-with-inflammatory-bowel-diseases
#10
JOURNAL ARTICLE
Bharati Kochar, Alison Rusher, Elizabeth Araka, Rachel Glasser, Jennifer Lai, Christine Ritchie, Ashwin N Ananthakrishnan
BACKGROUND: Despite the growing prevalence of older adults with inflammatory bowel diseases (IBD), polypharmacy, an important geriatric construct, is poorly understood. We described polypharmacy and its implications in older adults with IBD. METHODS: In a cross sectional study of adults ≥ 60 years with IBD, we obtained medication lists from the medical record and patients. We assessed medications by the Beer's criteria, anti-cholinergic burden and drug-drug interactions...
January 25, 2024: Digestive Diseases and Sciences
https://read.qxmd.com/read/38183404/performance-of-potentially-inappropriate-medications-assessment-tools-in-older-indian-patients-with-cancer
#11
JOURNAL ARTICLE
Sharath Kumar, Renita Castelino, Abhijith Rao, Shreya Gattani, Anita Kumar, Anupa Pillai, Arshiya Sehgal, Pallavi Rane, Anant Ramaswamy, Ratan Dhekale, Jyoti Krishnamurthy, Shripad Banavali, Rajendra Badwe, Kumar Prabhash, Vanita Noronha, Vikram Gota
BACKGROUND: Polypharmacy and potentially inappropriate medication (PIM) use are common problems in older adults. Safe prescription practices are a necessity. The tools employed for the identification of PIM sometimes do not concur with each other. METHODS: A retrospective analysis of patients ≥60 years who visited the Geriatric Oncology Clinic of the Tata Memorial Hospital, Mumbai, India from 2018 to 2021 was performed. Beer's-2015, STOPP/START criteria v2, PRISCUS-2010, Fit fOR The Aged (FORTA)-2018, and the EU(7)-PIM list-2015 were the tools used to assess PIM...
January 6, 2024: Cancer Medicine
https://read.qxmd.com/read/38124261/mapping-potentially-inappropriate-medications-in-older-adults-using-the-anatomical-therapeutic-chemical-atc-classification-system
#12
JOURNAL ARTICLE
Asinamai Ndai, Julie Al Bahou, Earl Morris, Hsin-Min Wang, Zach Marcum, Anna Hung, Nicole Brandt, Michael A Steinman, Scott Martin Vouri
BACKGROUND: Potentially inappropriate medications (PIMs) in older adults are medications in which risks often outweigh benefits and are suggested to be avoided. Worldwide, many distinct guidelines and tools classify PIMs in older adults. Collating these guidelines and tools, mapping them to a medication classification system, and creating a crosswalk will enhance the utility of PIM guidance for research and clinical practice. METHODS: We used the Anatomical Therapeutic Chemical (ATC) Classification System, a hierarchical classification system, to map PIMs from eight distinct guidelines and tools (2019 Beers Criteria, Screening Tool for Older Person's Appropriate Prescriptions [STOPP], STOPP-Japan, German PRISCUS, European Union-7 Potentially Inappropriate Medication [PIM] list, Centers for Medicare & Medicaid Services [CMS] High-Risk Medication, Anticholinergic Burden Scale, and Drug Burden Index)...
January 2024: Journal of the American Geriatrics Society
https://read.qxmd.com/read/38063911/-the-forta-fit-for-the-aged-list
#13
REVIEW
Farhad Pazan, Martin Wehling
BACKGROUND: Multimorbidity and the resulting polypharmacy are widespread in the very old and the evidence on the efficacy and safety of drugs in older people is sparse. Driven by guidelines, this often leads to inappropriate prescribing and drug-related problems. MATERIAL AND METHODS: To improve this, numerous listing approaches were developed as tools to optimize medication. These approaches can be divided into drug-oriented listing approaches (DOLA), such as the Beers Criteria®, a list of potentially inappropriate medications for older people or patient-in-focus listing approaches (PILA), such as the Fit fOR The Aged (FORTA) list...
December 8, 2023: Inn Med (Heidelb)
https://read.qxmd.com/read/38037179/potentially-inappropriate-medicine-use-and-predicting-risk-factors-in-hospitalized-older-adult-patients-findings-of-a-prospective-observational-study-from-ethiopia
#14
JOURNAL ARTICLE
Behailu Terefe Tesfaye, Dula Dessalegn Bosho, Gashahun Mekonnen Dissassa, Mikiyas Gashaw Tesfaye, Mengist Awoke Yizengaw
BACKGROUND: Older patients are fragile and more susceptible to medication-related problems requiring a strict assessment of their medicine list. The present study was conducted with the intention to assess the quality use of medicines in older adult patients by detecting potentially inappropriate medicine use and its predictive risk factors. METHODS: This prospective cross-sectional study involved 162 older medical patients admitted to Jimma Medical Center. A data abstraction format is employed to capture relevant information...
November 30, 2023: Journal of Pharmaceutical Policy and Practice
https://read.qxmd.com/read/38024485/potentially-inappropriate-medication-dispensing-in-outpatients-comparison-of-different-measurement-approaches
#15
JOURNAL ARTICLE
Yves Eggli, Patricia Halfon, Minette-Joëlle Zeukeng, Omar Kherad, Philippe Schaller, Marc-André Raetzo, Michael Frédéric Klay, Benoît Marc Favre, Dorian Schaller, Joachim Marti
PURPOSE OF THE RESEARCH: This paper aims at comparing different approaches to measure potentially inappropriate medication (PIM) with routinely collected data on prescriptions, patient age institutionalization status (ie in nursing home or in the community). A secondary objective is to measure the rate and prevalence of PIM dispensing and to identify problematic practices in Switzerland. MATERIAL AND METHODS: The studied population includes about 90,000 insured over 17 years old from a Swiss health maintenance organization in 2019 and 2020...
2023: Risk Management and Healthcare Policy
https://read.qxmd.com/read/37616291/potentially-inappropriate-medication-uses-and-associated-factors-among-elderly-primary-health-care-clinics-attendees-a-call-to-action
#16
JOURNAL ARTICLE
Esra'a Samara, Zaher Nazzal, Shayma Naghnaghia, Rowa' Al-Ramahi
BACKGROUND: Polypharmacy is a significant risk factor for using potentially inappropriate medication (PIM), which is using drugs with more risks than benefits, especially for elders. This study aimed to estimate the prevalence of PIM using Beers Criteria, polypharmacy, and their related risk factors. METHODS: A descriptive cross-sectional study was conducted in West Bank primary health care clinics (PHC)from December 2021 to March 2022. Data were collected from PHC clinic attendees aged 65 and above via an interviewer-administered questionnaire and a review of their medical records...
2023: PloS One
https://read.qxmd.com/read/37176508/potentially-inappropriate-medication-use-among-underserved-older-latino-adults
#17
JOURNAL ARTICLE
Ebony King, Mohsen Bazargan, Nana Entsuah, Sayaka W Tokumitsu, Cheryl Wisseh, Edward K Adinkrah
BACKGROUND: Previous studies identified alarming increases in medication use, polypharmacy, and the use of potentially inappropriate medications (PIMs) among minority older adults with multimorbidity. However, PIM use among underserved older Latino adults is still largely unknown. The main objective of this study is to examine the prevalence of PIM use among underserved, community-dwelling older Latino adults. This study examines both the complexity of polypharmacy in this community and identifies associations between PIM and multimorbidity, polypharmacy, and access to medical care among this segment of our population...
April 23, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37139824/american-geriatrics-society-2023-updated-ags-beers-criteria%C3%A2-for-potentially-inappropriate-medication-use-in-older-adults
#18
JOURNAL ARTICLE
(no author information available yet)
The American Geriatrics Society (AGS) Beers Criteria® (AGS Beers Criteria®) for Potentially Inappropriate Medication (PIM) Use in Older Adults is widely used by clinicians, educators, researchers, healthcare administrators, and regulators. Since 2011, the AGS has been the steward of the criteria and has produced updates on a regular cycle. The AGS Beers Criteria® is an explicit list of PIMs that are typically best avoided by older adults in most circumstances or under specific situations, such as in certain diseases or conditions...
July 2023: Journal of the American Geriatrics Society
https://read.qxmd.com/read/37105897/potentially-inappropriate-medications-and-polypharmacy-in-the-older-population-a-nationwide-cross-sectional-study-in-france-in-2019
#19
JOURNAL ARTICLE
Solène Drusch, Mahmoud Zureik, Marie Herr
AIM OF THE STUDY: To assess the prevalence of potentially inappropriate medications (PIMs) and polypharmacy in adults aged 75 years and over in France in 2019 based on data from the French health insurance claims database, at the national level and by region. METHODS: We conducted a cross-sectional study in French adults aged 75 years or over in 2019. We assessed the prevalence of seventeen PIM criteria adapted from the 2015 Beers and STOPP lists, as well as cumulative polypharmacy...
February 9, 2023: Thérapie
https://read.qxmd.com/read/37024805/associations-between-polypharmacy-and-potentially-inappropriate-medications-with-risk-of-falls-among-the-elderly-in-saudi-arabia
#20
JOURNAL ARTICLE
Khalid S AlHarkan, Safaa Alsousi, Mujtaba AlMishqab, Majd Alawami, Jaffar Almearaj, Hassan Alhashim, Hassan Alamrad, Layla M Alghamdi, Abdulelah Almansour, Reem S AlOmar
BACKGROUND: Falls are dangerous to the health of older adults and can impact their functional status leading to frailty. The use of potentially inappropriate medications (PIMs) among older adults may lead to adverse health outcomes and increase the risk of falls. Polypharmacy increases the incidence of falls. Beers criteria by the American Geriatric Society is one of the many criteria used to detect PIMs. It assesses the appropriateness of drug prescriptions (i.e., correct dose, duration, and indications) to ensure the safety of these drugs, reducing drug interactions and decreasing the hazards of side effects...
April 6, 2023: BMC Geriatrics
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