Lin Su, Fei Zhang, Ming-Xi Liu, Hong Li, Qiang Li, Yang-Zhuangzhuang Zhu, Yi-Fei Hou, Xiao Chen, Xiao-Yu Wang, Chun-Mei Qian, Chao Yao, Li-Xin Wang, Xiao-Ning Jiao, Xian-Dan Zhu, Zi-Hang Xu, Chun-Pu Zou
ETHNOPHARMACOLOGICAL RELEVANCE: The traditional Chinese medicine (TCM) Tian-Men-Dong decoction (TD) has been able to effectively treat lung cancer in China for thousands of years. TD improves the quality of life in lung cancer patients by promoting nourishment of yin and reducing dryness, clearing the lung and removing toxins. Pharmacological studies show that TD contains active antitumour ingredients, but its underlying mechanism remains unknown. AIM OF THE STUDY: This study aims at exploring potential mechanisms of TD in the treatment of lung cancer by regulating granulocytic-myeloid-derived suppressor cells (G-MDSCs)...
April 16, 2023: Journal of Ethnopharmacology