keyword
https://read.qxmd.com/read/38647358/the-beneficial-effect-of-%C3%AE-lipoic-acid-on-spinal-cord-injury-repair-in-rats-is-mediated-through-inhibition-of-oxidative-stress-a-transcriptomic-analysis
#1
JOURNAL ARTICLE
Ming-Ming Bian, Yao-Mei Xu, Lin Zhang, Hua-Zheng Yan, Jian-Xiong Gao, Gui-Qiang Fu, Yang-Yang Wang, He-Zuo Lü
BACKGROUND: Oxidative stress is a crucial factor contributing to the occurrence and development of secondary damage in spinal cord injuries (SCI), ultimately impacting the recovery process. α-lipoic acid (ALA) exhibits potent antioxidant properties, effectively reducing secondary damage and providing neuroprotective benefits. However, the precise mechanism by which ALA plays its antioxidant role remains unknown. METHODS: We established a model of moderate spinal cord contusion in rats...
April 22, 2024: Journal of Spinal Cord Medicine
https://read.qxmd.com/read/38644078/harnessing-artificial-intelligence-in-bariatric-surgery-comparative-analysis-of-chatgpt-4-bing-and-bard-in-generating-clinician-level-bariatric-surgery-recommendations
#2
REVIEW
Yung Lee, Thomas Shin, Léa Tessier, Arshia Javidan, James Jung, Dennis Hong, Andrew T Strong, Tyler McKechnie, Sarah Malone, David Jin, Matthew Kroh, Jerry T Dang
BACKGROUND: The formulation of clinical recommendations pertaining to bariatric surgery is essential in guiding healthcare professionals. However, the extensive and continuously evolving body of literature in bariatric surgery presents considerable challenge for staying abreast of latest developments and efficient information acquisition. Artificial intelligence (AI) has the potential to streamline access to the salient points of clinical recommendations in bariatric surgery. OBJECTIVES: The study aims to appraise the quality and readability of AI-chat-generated answers to frequently asked clinical inquiries in the field of bariatric and metabolic surgery...
March 24, 2024: Surgery for Obesity and Related Diseases
https://read.qxmd.com/read/38641000/intra-operative-staff-radiation-exposure-during-aortic-endovascular-procedures
#3
JOURNAL ARTICLE
Nicolas Clauss, Salomé Kuntz, Benjamin Colvard, Mickael Ohana, Luc Mertz, Anne Lejay, Nabil Chakfe
INTRODUCTION: The risk of radiation exposure in the surgical operating room (OR) and/or cathlab is now well established. Complex endovascular procedures often require multiple approaches and different positioning of the staff members around the patient, potentially increasing the levels of radiations exposure. Our goal was to evaluate the levels of radiation exposure of the members of the staff during endovascular aortic procedures in order to propose radioprotection optimization. MATERIAL AND METHODS: We included 41 aortic endovascular procedures out of 114 procedures performed between 12/01/2014 and 31/08/2015 including 24 standard endovascular aortic aneurysm repair (EVAR), 7 EVAR with iliac branch (EVARib), 8 complex fenestrated/branched EVAR (F/B EVAR), 2 Thoracic EVAR (TEVAR)...
April 17, 2024: Annals of Vascular Surgery
https://read.qxmd.com/read/38638328/retroperitoneal-abscess-associated-with-closed-pelvic-ring-fracture-diagnosed-by-fine-free-air-on-initial-trauma-pan-computed-tomography-scan
#4
Yohei Yanagisawa, Miki Yoshida, Manami Doi, Tetsuya Hoshino, Yoshiaki Inoue, Masashi Yamazaki
The patient was a 49-year-old male. He had a closed fracture of the pelvic ring that was treated successfully by avoiding anterior pelvic ring stabilization because of the presence of microscopic free air in the retroperitoneal space behind the pubic bone on initial whole-body trauma computed tomography scan. For his pelvic ring injury, transiliac rod and screw fixation was performed without the need for a pubic symphysis plate by developing the retroperitoneal space. His retroperitoneal abscess was treated by minimally invasive treatment of retroperitoneal abscess with computed tomography-guided percutaneous drainage...
June 2024: Trauma Case Reports
https://read.qxmd.com/read/38632304/enhanced-read-resolution-in-reconfigurable-memristive-synapses-for-spiking-neural-networks
#5
JOURNAL ARTICLE
Hritom Das, Catherine Schuman, Nishith N Chakraborty, Garrett S Rose
The synapse is a key element circuit in any memristor-based neuromorphic computing system. A memristor is a two-terminal analog memory device. Memristive synapses suffer from various challenges including high voltage, SET or RESET failure, and READ margin issues that can degrade the distinguishability of stored weights. Enhancing READ resolution is very important to improving the reliability of memristive synapses. Usually, the READ resolution is very small for a memristive synapse with a 4-bit data precision...
April 17, 2024: Scientific Reports
https://read.qxmd.com/read/38631239/substrate-promiscuity-of-xenobiotic-transforming-hydrolases-from-stream-biofilms-impacted-by-treated-wastewater
#6
JOURNAL ARTICLE
Yaochun Yu, Niklas Ferenc Trottmann, Milo R Schärer, Kathrin Fenner, Serina L Robinson
Organic contaminants enter aquatic ecosystems from various sources, including wastewater treatment plant effluent. Freshwater biofilms play a major role in the removal of organic contaminants from receiving water bodies, but knowledge of the molecular mechanisms driving contaminant biotransformations in complex stream biofilm (periphyton) communities remains limited. Previously, we demonstrated that biofilms in experimental flume systems grown at higher ratios of treated wastewater (WW) to stream water displayed an increased biotransformation potential for a number of organic contaminants...
April 10, 2024: Water Research
https://read.qxmd.com/read/38628989/a-rare-case-of-a-patient-being-alert-and-communicative-despite-severe-hypothermia
#7
Emile Jeunesse, Patrick O'Malley, Nick Petrus, Chelsea McCoy
Hypothermia is defined as a significant drop in core body temperature below 35°C (95°F). It is traditionally staged as mild, moderate, severe, and profound at temperatures of 35°C to 32°C (95°F to 89.6°F), 32°C to 28°C (89.6°F to 82.4°F), <28°C (<82.4°F), and <24°C (75.2°F), respectively. It can also be classified into the same stages by clinical presentations. We present a patient that fits into two different stages based on core body temperature and clinical presentation...
March 2024: Curēus
https://read.qxmd.com/read/38626267/evidence-for-vagal-sensory-neural-involvement-in-influenza-pathogenesis-and-disease
#8
JOURNAL ARTICLE
Nathalie A J Verzele, Brendon Y Chua, Kirsty R Short, Aung Aung Kywe Moe, Isaac N Edwards, Helle Bielefeldt-Ohmann, Katina D Hulme, Ellesandra C Noye, Marcus Z W Tong, Patrick C Reading, Matthew W Trewella, Stuart B Mazzone, Alice E McGovern
Influenza A virus (IAV) is a common respiratory pathogen and a global cause of significant and often severe morbidity. Although inflammatory immune responses to IAV infections are well described, little is known about how neuroimmune processes contribute to IAV pathogenesis. In the present study, we employed surgical, genetic, and pharmacological approaches to manipulate pulmonary vagal sensory neuron innervation and activity in the lungs to explore potential crosstalk between pulmonary sensory neurons and immune processes...
April 16, 2024: PLoS Pathogens
https://read.qxmd.com/read/38610417/response-of-the-teros-12-soil-moisture-sensor-under-different-soils-and-variable-electrical-conductivity
#9
JOURNAL ARTICLE
Athanasios Fragkos, Dimitrios Loukatos, Georgios Kargas, Konstantinos G Arvanitis
In this work, the performance of the TEROS 12 electromagnetic sensor, which measures volumetric soil water content (θ), bulk soil electrical conductivity (σb ), and temperature, is examined for a number of different soils, different θ and different levels of the electrical conductivity of the soil solution (ECW ) under laboratory conditions. For the above reason, a prototype device was developed including a low-cost microcontroller and suitable adaptation circuits for the aforementioned sensor...
March 29, 2024: Sensors
https://read.qxmd.com/read/38608959/total-bacterial-count-and-somatic-cell-count-in-bulk-and-individual-goat-milk-around-kidding-two-longitudinal-observational-studies
#10
JOURNAL ARTICLE
Y de Geus, P Scherpenisse, L A M Smit, A Bossers, J A Stegeman, L Benedictus, L Spieß, G Koop
Total bacterial count (TBC) and somatic cell count (SCC) are important quality parameters in goat milk. Exceeding the bulk milk TBC (BMTBC) thresholds leads to price penalties for Dutch dairy goat farmers. Controlling these milk quality parameters can be challenging, especially around kidding. First, we describe the variation and the peaks around kidding of TBC and SCC in census data on Dutch bulk milk over the last 22 years. Second, to explore causes of these elevations, we studied the variation of TBC and SCC in individual goat milk from 3 weeks before to 5 weeks after kidding and their association with systemic response markers interferon-γ (IFN-γ), calprotectin, β-hydroxybutyrate (BHB), body condition score (BCS) and fecal consistency...
April 10, 2024: Journal of Dairy Science
https://read.qxmd.com/read/38608922/safety-evaluation-of-8-drug-degradants-present-in-over-the-counter-cough-and-cold-medications
#11
JOURNAL ARTICLE
Amy L Mihalchik, Neepa Y Choksi, Amy L Roe, Michael Wisser, Kylen Whitaker, Donna Seibert, Milind Deore, Larisa Pavlick, Daniele S Wikoff
Although the United States Food & Drug Administration (FDA) has provided guidance on the control of drug degradants for prescription drugs, there is less guidance on how to set degradant specifications for FDA OTC monograph drugs. Given that extensive impurity testing was not part of the safety paradigm in original OTC monographs, a weight of evidence (WOE) approach to qualify OTC degradants is proposed. This approach relies on in silico tools and read-across approaches alongside standard toxicity testing to determine safety...
April 10, 2024: Regulatory Toxicology and Pharmacology: RTP
https://read.qxmd.com/read/38605265/the-effects-of-heart-rhythm-meditation-on-vagal-tone-and-well-being-%C3%A2-a-mixed-methods-research-study
#12
JOURNAL ARTICLE
Elizabeth J Tisdell, Branka Lukic, Ruhi Banerjee, Duanping Liao, Charles Palmer
Many studies have examined the effects of meditation practice focused on the normal breath on vagal tone with mixed results. Heart Rhythm Meditation (HRM) is a unique meditation form that engages in the deep slow full breath, and puts the focus of attention on the heart. This form of breathing likely stimulates the vagus nerve with greater intensity. The purpose of this study was (a) to examine how the practice of HRM affects vagal activity as measured by heart rate variability (HRV); and (b) to examine how it affects participants' well-being...
April 12, 2024: Applied Psychophysiology and Biofeedback
https://read.qxmd.com/read/38598698/validation-of-pulse-oxygen-saturation-heart-rate-blood-pressure-and-respiratory-rate-raised-by-a-contactless-telehealth-portal-validation-study
#13
JOURNAL ARTICLE
Julian Gerald Dcruz, Paichang Yeh
BACKGROUND: The traditional measurement of these vitals via physical examination has become challenging and the recent pandemic has accelerated trends towards telehealth and remote monitoring. Instead of going to the physician for checking Heart Rate, Oxygen Saturation (SPO2), Blood Pressure, Body Temperature and Respiration Rate it would be excellent if it could be measured at home. Vital signs monitors, also known as physiological parameter monitors, are electronic devices that measure and display biological information about patients under constant monitoring...
April 4, 2024: JMIR Formative Research
https://read.qxmd.com/read/38594267/augmenting-authenticity-for-non-invasive-in-vivo-detection-of-random-blood-glucose-with-photoacoustic-spectroscopy-using-kernel-based-ridge-regression
#14
JOURNAL ARTICLE
P N S B S V Prasad V, Ali Hussain Syed, Mudigonda Himansh, Biswabandhu Jana, Pranab Mandal, Pradyut Kumar Sanki
Photoacoustic Spectroscopy (PAS) is a potential method for the noninvasive detection of blood glucose. However random blood glucose testing can help to diagnose diabetes at an early stage and is crucial for managing and preventing complications with diabetes. In order to improve the diagnosis, control, and treatment of Diabetes Mellitus, an appropriate approach of noninvasive random blood glucose is required for glucose monitoring. A polynomial kernel-based ridge regression is proposed in this paper to detect random blood glucose accurately using PAS...
April 9, 2024: Scientific Reports
https://read.qxmd.com/read/38591567/identification-and-expression-patterns-of-somatic-pirnas-and-piwi-genes-in-riptortus-pedestris-hemiptera-alydidae
#15
JOURNAL ARTICLE
Yipeng Ren, Wenhao Dong, Wenjun Bu, Huaijun Xue
RNA interference (RNAi)-based gene silencing is a feasible and sustainable technology for the management of hemipteran pests by double-stranded RNA involvement, including small-interfering RNA, microRNA, and Piwi-interacting RNA (piRNA) pathways, that may help to decrease the usage of chemical insecticides. However, only a few data are available on the somatic piRNAs and their biogenesis genes in Riptortus pedestris, which serves as a significant pest of soybean (Glycine max). In this study, two family members of the PIWI gene were identified and characterized in R...
April 2024: Archives of Insect Biochemistry and Physiology
https://read.qxmd.com/read/38591175/impaired-ability-in-visual-spatial-attention-in-chinese-children-with-developmental-dyslexia
#16
JOURNAL ARTICLE
Mengyu Tian, Yuzhu Ji, Runzhou Wang, Hong-Yan Bi
A growing body of evidence suggests that children with dyslexia in alphabetic languages exhibit visual-spatial attention deficits that can obstruct reading acquisition by impairing their phonological decoding skills. However, it remains an open question whether these visual-spatial attention deficits are present in children with dyslexia in non-alphabetic languages. Chinese, with its logographic writing system, offers a unique opportunity to explore this question. The presence of visual-spatial attention deficits in Chinese children with dyslexia remains insufficiently investigated...
April 9, 2024: Journal of Learning Disabilities
https://read.qxmd.com/read/38590308/artificial-intelligence-powered-glucose-monitoring-and-controlling-system-pumping-module
#17
JOURNAL ARTICLE
Sravani Medanki, Nikhil Dommati, Hema Harshitha Bodapati, Venkata Naga Sai Kowsik Katru, Gollapalli Moses, Abhishek Komaraju, Nanda Sai Donepudi, Dhanya Yalamanchili, Jasti Sateesh, Pratap Turimerla
BACKGROUND: Diabetes, a globally escalating health concern, necessitates innovative solutions for efficient detection and management. Blood glucose control is an essential aspect of managing diabetes and finding the most effective ways to control it. The latest findings suggest that a basal insulin administration rate and a single, high-concentration injection before a meal may not be sufficient to maintain healthy blood glucose levels. While the basal insulin rate treatment can stabilize blood glucose levels over the long term, it may not be enough to bring the levels below the post-meal limit after 60 min...
March 20, 2024: World Journal of Experimental Medicine
https://read.qxmd.com/read/38588789/effect-of-a-comprehensive-school-based-health-center-on-academic-growth-in-k-8-th-grade-students
#18
JOURNAL ARTICLE
Katherine A Connor, Paul Spin, Brandon M Smith, Beth R Marshall, Gabriela V Calderon, Laura Prichett, Vanya C Jones, Ryan Connor, Tina L Cheng, Lauren M Klein, Sara B Johnson
OBJECTIVE: School-based health centers (SBHCs) improve healthcare access, but associations with educational outcomes are mixed and limited for elementary and middle school students. We investigated whether students enrolled in a comprehensive SBHC demonstrated more growth in standardized math and reading assessments over four school years versus non-enrolled students. We also explored changes in absenteeism. METHODS: Participants were students enrolled in two co-located Title I schools from 2015-19 (1 elementary, 1 middle, n=2,480)...
April 6, 2024: Academic Pediatrics
https://read.qxmd.com/read/38587612/the-role-of-body-object-interaction-in-children-s-concept-processing-insights-from-two-chinese-communities
#19
JOURNAL ARTICLE
Zhengye Xu, Duo Liu
A rating of body-object interactions (BOIs) reflects the ease with which a human body can interact physically with a word's referent. Studies with adults have demonstrated a facilitating BOI effect in language tasks, with faster and more accurate responses for high BOI words (e.g., cup) than low BOI words (e.g., coal). A few studies have explored the BOI effect in children. However, these studies have all adopted adult-rated BOIs, which may differ from children's. Using child-rated BOIs, the present study investigated the BOI effect in Chinese children and its relationship with age, as well as whether there was a community difference in the BOI effect...
April 8, 2024: Cognitive Processing
https://read.qxmd.com/read/38580461/-not-available
#20
JOURNAL ARTICLE
Abdellatif Moustatraf, Fatima Touhami
INTRODUCTION: Morocco is carrying out several actions to generalize basic compulsory health insurance (CHI). Managing this project requires coordination, information sharing, and the commitment of all actors to the goal of covering an additional 22 million people. One of the key factors for achieving this objective is the implementation of a unified registration system. PURPOSE OF THE RESEARCH: The aim is to analyze the existing situation and the feasibility of implementing a unified registration system, and to describe the potential positive impact of the latter on the extension of CHI...
2024: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
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