Read by QxMD icon Read

Quantum health

Takashi Ito, Hisahiro Sasabe, Yuji Nagai, Yuichiro Watanabe, Natsuki Onuma, Junji Kido
Deep red to near-infrared (NIR) OLEDs, which yield emission peak wavelengths beyond 660 nm, are applicable as a unique light source in plant growth or health-monitoring systems. Compared with other visible spectrum region OLEDs, however, research in the field of deep red OLEDs is not as advanced. In this work, three new types of dibenzofuran-based host materials are developed as n-type exciplex host partners. Combining these with a deep red iridium complex, bis(2,3-diphenylquinoxaline)iridium(dipivaloylmethane) [(DPQ)2Ir(dpm)] and NPD as a p-type exciplex host partner, a highly efficient deep red OLED can be realized with a maximum external quantum efficiency (EQE) of over 16% with Comission Internationale de l'Éclairge (CIE) coordinates of (0...
February 11, 2019: Chemistry: a European Journal
Guilherme P C Mello, Eliana F C Simões, Diana M A Crista, João M M Leitão, Luís Pinto da Silva, Joaquim C G Esteves da Silva
Diabetes mellitus is a chronic disease and leading cause of death worldwide, affecting more than 420 million people. High blood glucose levels are a common effect of uncontrolled diabetes, which can cause serious health damage. Diabetic individuals must measure their blood glucose levels regularly in order to control glycemic levels and minimize the effects of the disease. Glucose sensors have been used in the management of diabetes for more than 50 years, when Clark and Ann Lyons developed the first glucose enzyme electrode in 1962...
February 10, 2019: Critical Reviews in Analytical Chemistry
Min Wei, Chunlei Wang, Ensheng Xu, Jin Chen, Xiaolin Xu, Wei Wei, Songqin Liu
Ochratoxin A (OTA) poses a serious threat to the health of human beings and animals. In this paper, a simple and sensitive electrochemiluminescence (ECL) aptasensor was constructed to detect OTA based on electrochemiluminescence resonance energy transfer (ECL-RET) and a nicking endonuclease-powered DNA walking machine. Originally, the signal of cadmium sulfide semiconductor quantum dots (CdS QDs) was quenched efficiently by Cy5. After the addition of OTA, the walker autonomously hybridized with Cy5-labeled DNA and released plenty of Cy5-DNA from the electrode surface with the help of a nicking endonuclease...
June 1, 2019: Food Chemistry
Nerea De Acha, César Elosúa, Jesús M Corres, Francisco J Arregui
Due to the risks that water contamination implies for human health and environmental protection, monitoring the quality of water is a major concern of the present era. Therefore, in recent years several efforts have been dedicated to the development of fast, sensitive, and selective sensors for the detection of heavy metal ions. In particular, fluorescent sensors have gained in popularity due to their interesting features, such as high specificity, sensitivity, and reversibility. Thus, this review is devoted to the recent advances in fluorescent sensors for the monitoring of these contaminants, and special focus is placed on those devices based on fluorescent aptasensors, quantum dots, and organic dyes...
January 31, 2019: Sensors
Amel M Garbou, Muqiong Liu, Shengli Zou, Cherie L Yestrebsky
Hexachlorobenzene (HCB), like many chlorinated organic compounds, has accumulated in the environment from agricultural and industrial activity. Because of its health risks and adverse impact on various ecosystems, remediation of this contaminant is of vital concern. The objective of this study is to evaluate the proficiency of activated magnesium metal in a protic solvent system to accomplish reductive dechlorination of HCB. Experimental results were compared with those predicted by quantum chemical calculations based on Density Functional Theory (DFT)...
January 25, 2019: Chemosphere
Kenshin Takemura, Oluwasesan Adegoke, Tetsuro Suzuki, Enoch Y Park
Among the members of flaviviruses, the Zika virus (ZIKV) remains a potent infectious disease agent, with its associated pandemic prompting the World Health Organization (WHO) to declare it a global public health concern. Thus, rapid and accurate diagnosis of the ZIKV is needed. In this study, we report a new immunofluorescence biosensor for the detection of nonstructural protein 1 (NS1) of the ZIKV, which operates using the localized surface plasmon resonance (LSPR) signal from plasmonic gold nanoparticles (AuNPs) to amplify the fluorescence intensity signal of quantum dots (QDs) within an antigen-antibody detection process...
2019: PloS One
Cheng-Che E Lan
Solar radiation is one of fundamental elements sustaining and maintaining life on earth. Previous studies on health effects from the sun exposure mostly focused on ultraviolet (UV) radiation. Although exposure to the solar radiation likely occurs in an environment with elevated temperature, the effects and interactions of elevated environmental temperature with UV radiation on the skin, especially in the context of ageing and carcinogenesis, have not been carefully examined. It is known that UVA radiation results in reduced production and increased degradation of dermal collagen, contributing to photoageing of the skin...
February 2019: Experimental Dermatology
Abu Asaduzzaman, Demian Riccardi, Akef T Afaneh, Sarah J Cooper, Jeremy C Smith, Feiyue Wang, Jerry M Parks, Georg Schreckenbach
Mercury (Hg) is a global environmental contaminant. Major anthropogenic sources of Hg emission include gold mining and the burning of fossil fuels. Once deposited in aquatic environments, Hg can undergo redox reactions, form complexes with ligands, and adsorb onto particles. It can also be methylated by microorganisms. Mercury, especially its methylated form methylmercury, can be taken up by organisms, where it bioaccumulates and biomagnifies in the food chain, leading to detrimental effects on ecosystem and human health...
January 28, 2019: Accounts of Chemical Research
Hangqing Xie, Yao Fu, Qizhen Zhang, Kun Yan, Run Yang, Kaihui Mao, Paul K Chu, Lizhe Liu, Xinglong Wu
Label-free detection of ascorbic acid (AA) with high sensitivity and specificity based on the effects of AA on fluorescence quenching of carbon nitride quantum dots (CNQDs) is described. The CNQDs with a high fluorescence quantum yield of 21% and good dispersibility in water are prepared by reacting g-C3 N4 sheets with ethylenediamine (EN). Fluorescence at 510 nm from the CNQDs is quenched gradually by addition of AA. As the AA concentration increases, the activity of the lone pair (LP) state of the CNQDs diminishes resulting in reduced fluorescence from the CNQDs and the mechanism of the static quenching effect is discussed...
May 1, 2019: Talanta
Yanling Ma, Fei Yan, Li Liu, WuJie Wei, Zhenyu Zhao, Jianhai Sun
Cancer is one of the death causing disease is always being a public health concern due to its rapid increase in the world population. Hyperthermal therapy is an anticancer treatment mutually given with chemotherapy. In the present study, CdS/rGO nanocomposites were synthesized using simple and scalable solvothermal method and applied as an efficient material in anticancer treatment. The prepared nanocomposites were characterized from physicochemical characterization techniques. The surface morphology and the crystallographic details were obtained from TEM and XRD analyses respectively...
December 18, 2018: Journal of Photochemistry and Photobiology. B, Biology
David K Scoville, James D Nolin, H Luke Ogden, Dowon An, Zahra Afsharinejad, Brian W Johnson, Theo K Bammler, Xiaohu Gao, Charles W Frevert, William A Altemeier, Teal S Hallstrand, Terrance J Kavanagh
Quantum dot nanoparticles (QDs) are engineered nanomaterials (ENMs) that have utility in many industries due to unique optical properties not available in small molecules or bulk materials. QD-induced acute lung inflammation and toxicity in rodent models raise concerns about potential human health risks. Recent studies have also shown that some ENMs can exacerbate allergic airway disease (AAD). In this study, C57BL/6J and A/J mice were exposed to saline, house dust mite (HDM), or a combination of HDM and QDs on day 1 of the sensitization protocol...
January 22, 2019: Toxicology and Applied Pharmacology
Alison Ritter, Richard Mellor, Jenny Chalmers, Matthew Sunderland, Kari Lancaster
OBJECTIVE: Estimates of the extent of treatment need (defined by the presence of a diagnosis for which there is an effective treatment available) and treatment demand (defined as treatment seeking) are essential parts of effective treatment planning, service provision, and treatment funding. This article reviews the existing literature on approaches to estimating need and demand and the use of models to inform such estimation, and then considers the implications for health planners. METHOD: A thematic review of the literature was undertaken, with a focus on covering the key concepts and research methods that have been used to date...
January 2019: Journal of Studies on Alcohol and Drugs. Supplement
Qian Wang, Lingling Zhao, Haoan Zhao, Xinyan Liu, Liguo Gao, Ni Cheng, Wei Cao
The interactions of (CH3 COO)2 Pb·3H2 O (lead acetate trihydrate) with luteolin, 5,7,3',4'-tetrahydroxyflavone, were investigated in methanol solution. The spectroscopy (UV-Vis, FT-IR, HPLC-MS, 1 H NMR) and elemental analysis were adopted to assess the interaction of luteolin and Pb(II). The results show that luteolin reacts with Pb(II) through the chelating sites of 4‑carbonyl and 5-hydroxy in two luteolin molecules. The structures, energies, CDA (charge decomposition analysis) and orbitals analysis of the ligand and complex have been analyzed according to quantum-chemical calculation, which is further proofed that luteolin molecule can effectively chelate Pb(II) by 5-hydroxyl-4-oxo chelating site...
January 15, 2019: Journal of Inorganic Biochemistry
Jian Zhang, Jingjing Qian, Qingsong Mei, Lei Yang, Lifang He, Shengjun Liu, Cheng Zhang, Kui Zhang
Herein, a ratiometric fluorescence sensing strategy coupled with smartphone imaging-based sensing platform was proposed for the on-site determination of fluoride ion (F- ) with high sensitivity and accuracy. The principle of sensing strategy is based on the fluoride-promoted Si-O bond cleavage of 2-(tert-butyldiphenylsilyloxy)phenol (2-TBDPSP) to release 2-hydroxyphenolate, which rapidly auto-oxidized to ortho-quinone. As excellent electron acceptor, these quinone species covalently bonded on the surface of dual-emission amino-modified quantum dots (QDs) nanohybrid via a Michael's type adduction, quenching the fluorescence of green-emitting QDs on the surface of the nanohybrid, while not affecting the fluorescence of red-emitting QDs embedding silica nanospheres...
December 29, 2018: Biosensors & Bioelectronics
Haitao Wang, Shan Liu, Yukun Song, Bei-Wei Zhu, Mingqian Tan
Nanosized materials may produce adverse physiological effects or potential health risks due to their unique physical and chemical properties. Herein, the universal presence of fluorescent carbon dots (CDs) in commercial beers was confirmed through a systematic survey. The beer CDs were roughly spherically shaped in appearance and emitted bright blue fluorescence under ultraviolet light with quantum yields (QYs) ranging from 1.42% to 3.92%. Furthermore, digestion, biodistribution, and cytotoxicity assessments of CDs from Snow beer were conducted as an example...
January 9, 2019: Nanotoxicology
Zhan Zhou, Jiapei Gu, Yuze Chen, Xiaoxia Zhang, Haixia Wu, Xiaoguang Qiao
Bacillus anthracis spore causes anthrax to seriously threaten human health and even cause death. 2,6-Pyridinedicarboxylic acid (DPA) is a unique biomarker because it is a major component of Bacillus anthracis spore. Herein, we design europium functionalized silicon quantum dots as a ratiometric fluorescent nanoprobe to detect DPA with high sensitivity and selectivity. With the addition of DPA, the red emission peaks were observed at 618 nm. The novel probe enables ratiometric and sensitive DPA detection over nanomolar concentrations (as low as 1...
December 21, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Reena Siwach, Parijat Pandey, Viney Chawla, Harish Dureja
BACKGROUND: Diabetes Mellitus (DM) has emerged as an epidemic that has affected millions of people worldwide in the last few decades. Nanotechnology is a discipline that is concerned with material characteristics at nanoscale and offers novel techniques for disease detection, management and prevention. OBJECTIVE: Diabetes mellitus is an epidemic disease that has affected millions of people globally. Nanotechnology has greatly enhanced the health status by providing non-obtrusive techniques for the management and treatment of diabetic patients...
January 4, 2019: Recent Patents on Nanotechnology
Aurelie Perrier, Matthias Eluard, Michel Petitjean, Anne Vanet
The RNA virus Influenza A is a serious public health problem with every year epidemics resulting in more than 250,000 deaths. A target zone was identified on the HA2 subunit of the hemagglutinin responsible for the entry of the virus into the host cell by endocytosis. The binding of a ligand in this zone rich in invariant residues and synthetic lethal couples, could prevent therapeutic escape and inhibit the conformational change at pH=5 initiating the membrane fusion in the endosome. Two pentapeptides, a linear peptide (EQRRS) and a cyclic peptide (DQRRD) have been proposed as potential drugs...
December 28, 2018: Journal of Physical Chemistry. B
Changsoon Choi, Youngsik Lee, Kyoung Won Cho, Ja Hoon Koo, Dae-Hyeong Kim
Soft bioelectronics intended for application to wearable and implantable biomedical devices have attracted great attention from material scientists, device engineers, and clinicians because of their extremely soft mechanical properties that match with a variety of human organs and tissues, including the brain, heart, skin, eye, muscles, and neurons, as well as their wide diversity in device designs and biomedical functions that can be finely tuned for each specific case of applications. These unique features of the soft bioelectronics have allowed minimal mechanical and biological damage to organs and tissues integrated with bioelectronic devices and reduced side effects including inflammation, skin irritation, and immune responses even after long-term biointegration...
December 26, 2018: Accounts of Chemical Research
Li Mu, Qixing Zhou, Yujie Zhao, Xiaowei Liu, Xiangang Hu
Oil spills occur frequently worldwide, resulting in severe damage to water and to human health. Polycyclic aromatic hydrocarbons (PAHs) are the primary toxic components in oil contamination. PAH-degrading microbes have attracted significant attention, but difficulty in their selection and proliferation limits their applications. Graphene oxide quantum dots (GOQDs) improve the proliferation of an indigenous PAH-degrading strain, Bacillus cereus, more effectively than large graphene oxide flakes. Bacillus cereus can metabolize a variety of xenobiotic aromatic compounds as carbon sources and is used in bioremediation...
December 14, 2018: Journal of Hazardous Materials
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"