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Jennina Taylor-Wells, Aaron D Gross, Shiyao Jiang, Fabien Demares, Joseph S Clements, Paul R Carlier, Jeffrey R Bloomquist
The present study focused on the toxicity of the aphid anti-feedant flonicamid and its main metabolite, 4-trifluoromethylnicotinamide (TFNA-AM) to Aedes aegypti and Anopheles gambiae mosquitoes. The compounds were toxic to both species via topical application, resulting in un-coordinated locomotion and leg splaying, with a favorable An. gambiae LD50 value of 35 ng/mg for TFNA-AM, but no significant lethality to Ae. aegypti at 10 μg/female. There was mild cross resistance in the Akron-kdr (Akdr) strain of An...
October 2018: Pesticide Biochemistry and Physiology
Huan Yuan, Yves Acklin, Peter Varga, Boyko Gueorguiev, Markus Windolf, Devakar Epari, Michael Schuetz, Beat Schmutz
INTRODUCTION: Anatomic fit of intramedullary nails was suggested by previous studies to improve significantly when the nail radius of curvature (ROC) is closer to the average femoral anatomy. However, no attempt has been made to investigate the impact of different ROC designs on the nail insertion process. Therefore, this biomechanical study quantitatively compared the ease of insertion between femoral intramedullary nails with a 1.0-m and a 1.5-m bow radius. MATERIALS AND METHODS: Long TFN-ADVANCED™ (TFNA, 1...
May 2017: Archives of Orthopaedic and Trauma Surgery
Rosalía López-Ruiz, Roberto Romero-González, José Luis Martínez Vidal, Antonia Garrido Frenich
The development and validation of a method to determine flonicamid and its metabolites as TFNA (4-trifluoromethylnicotinic acid), TFNG (N-(4-trifluoromethylnicotinoyl) glycine) and TFNA-AM (4-trifluoromethylnicotinamide) in bell pepper samples by ultra-high-performance liquid chromatography coupled to Orbitrap mass spectrometry (UHPLC-Orbitrap-MS) was performed. A fast and simple extraction procedure with acidified acetonitrile and salts (magnesium sulfate and sodium chloride) was used. The methodology was validated, checking for specificity, recovery, precision, limits of detection (LODs) and limits of quantification (LOQs)...
November 2016: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Beat Schmutz, Jayani Amarathunga, Stanley Kmiec, Prasad Yarlagadda, Michael Schuetz
BACKGROUND: The radius of curvature (ROC) misfit of cephalomedullary nails during anterograde nailing can lead to complications such as distal anterior cortical encroachment. This study quantified the anatomical fit of a new nail with 1.0-m ROC (TFN-ADVANCED(™) Proximal Femoral Nailing System [TFNA]) compared with a nail with 1.5-m ROC (Gamma3 Long Nail R1.5 [Gamma3]). METHODS: We generated 63 three-dimensional models (48 female, 45 right femur) representing the cortical surfaces of the femora (31 Caucasian, 28 Japanese, and 4 Thai)...
April 27, 2016: Journal of Orthopaedic Surgery and Research
Da-I Jung, Waziha Farha, A M Abd El-Aty, Sung-Woo Kim, Md Musfiqur Rahman, Jeong-Heui Choi, Md Humayun Kabir, So Jeong Im, Young-Jun Lee, Lieu T B Truong, Ho-Chul Shin, Geon-Jae Im, Jae-Han Shim
The degradation behavior of flonicamid and its metabolites (4-trifluoromethylnicotinic acid (TFNA) and N-(4-trifluoromethylnicotinoyl) glycine (TFNG)) was evaluated in red bell pepper over a period of 90 days under glass house conditions, including high temperature, low and high humidity, and in a vinyl house covered with high density polyethylene light shade covering film (35 and 75%). Flonicamid (10% active ingredient) was applied (via foliar application) to all fruits, including those groups grown under normal conditions (glass house) or under no shade cover (vinyl house)...
March 2016: Environmental Monitoring and Assessment
Simenew Keskes Melaku, Fekadu Regassa, Tesfaye Sisay Tessema, Tesfu Kassa, Juri Vencato, David Okello Owiny, Calogero Stelletta
The aim of this study was to evaluate testicular cytological profiles of apparently healthy dromedary bulls during rutting and non-rutting periods. Pairs of testes from 26 (18 non-rutting and 8 rutting seasons) dromedary bulls 6-12 years old that were slaughtered at Akaki, Addis Ababa abattoir were sampled. A 21 gauge needle attached to 20mL syringe was used to collect Testicular Fine Needle Aspiration (TFNA) samples and five aspiration smears were prepared from each testis. A total of 312 slides (260 Testicular fine Needle Aspiration and 52 imprints) were examined...
December 2015: Animal Reproduction Science
Emad Raddaoui, Esam H Alhamad, Shaesta Naseem Zaidi, Maha Arafah, Fatmah Fahad AlHabeeb
BACKGROUND: Endoscopic ultrasound-guided transbronchial fine-needle aspiration (EBUS-TFNA) is a minimally invasive technique for diagnosis of mediastinal masses/lesions. Although most studies have reported the utility of EBUS-TFNA in malignancy, its use has been extended to the benign conditions as well. OBJECTIVE: The present study focused on utility of EBUS in contributing to reach the final diagnosis of sarcoidosis. DESIGN: From May 2010 to December 2013, 19 of 80 patients who underwent EBUS-TFNA at one center for radiologically suspicious lesions for sarcoidosis, and with no definite histological diagnosis, were included in this retrospective study...
2014: CytoJournal
Emad Raddaoui, Esam H Alhamad, Shaesta Naseem Zaidi, Fatmah F Al-Habeeb, Maha Arafah
OBJECTIVE: The objective of this study is to evaluate the cytological accuracy of endobronchial ultrasound-guided transbronchial fine-needle aspiration (EBUS-TFNA) of the mediastinal mass/nodular lesions. STUDY DESIGN: Over 3½ years from inception at King Khalid University Hospital, a retrospective analysis of the cytological diagnoses of all the EBUS-TFNA procedures performed in 80 patients who had mediastinal mass/nodular enlargement. Cytology results were reviewed and correlated with the histologic follow-up...
2014: CytoJournal
Douglas M Minot, Elizabeth A Gilman, Marie-Christine Aubry, Jesse S Voss, Sarah G Van Epps, Delores J Tuve, Andrew P Sciallis, Michael R Henry, Diva R Salomao, Peter Lee, Stephanie K Carlson, Amy C Clayton
Transthoracic fine needle aspiration (TFNA)/core needle biopsy (CNB) under computed tomography (CT) guidance has proved useful in the assessment of pulmonary nodules. We sought to determine the TFNA false-negative (FN) rate at our institution and identify potential causes of FN diagnoses. Medical records were reviewed from 1,043 consecutive patients who underwent CT-guided TFNA with or without CNB of lung nodules over a 5-year time period (2003-2007). Thirty-seven FN cases of "negative" TFNA/CNB with malignant outcome were identified with 36 cases available for review, of which 35 had a corresponding CNB...
December 2014: Diagnostic Cytopathology
Vighnesh Walavalkar, Andrew H Fischer, Christopher L Owens
BACKGROUND: Metastases to the thyroid gland, although rare, are important entities to consider when evaluating malignant cells on a thyroid fine-needle aspiration (TFNA) specimen. Cellular TFNA specimens with small round blue cells should prompt a broad differential: florid lymphocytic thyroiditis, lymphoma, metastases, as well as primary thyroid malignancies with similar morphologies such as poorly differentiated (insular) and medullary carcinomas. Age, clinical presentation and prior history must be considered in every case...
2014: Acta Cytologica
Esra Yazar, Funda Seçik, Pınar Yıldız
BACKGROUND: Transthoracic fine needle aspiration biopsy is a well-established and safe technique for obtaining pulmonary tissue. However, there is very little data about repeating procedure. OBJECTIVES: We aimed to investigate whether repeating CT-guided transthoracic fine needle aspiration (TFNA) increases diagnostic yield and complication rate. PATIENTS AND METHODS: Patients underwent TFNA and the final diagnoses achieved were included in the study...
June 2013: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
Irene Gázquez, Antonia Moreno, Teresa Requena, Jeff Ohmen, Sofia Santos-Perez, Ismael Aran, Andres Soto-Varela, Herminio Pérez-Garrigues, Alicia López-Nevot, Angel Batuecas, Rick A Friedman, Miguel A López-Nevot, Jose A López-Escamez
Variability in acute immune response genes could determine susceptibility or prognosis for Ménière's disease (MD). The cytokines tumor necrosis factor α (TNFα), macrophage migration inhibitory factor (MIF) and interferon γ (INFγ) are proinflammatory cytokines of the innate immune response. These cytokines mediate inflammation and have been previously associated with the inflammatory process in several autoimmune diseases. We investigated the association between functional allelic variants of MIF (rs35688089), IFNG (rs2234688) and TNFA (rs1800629) in patients with MD...
March 2013: European Archives of Oto-rhino-laryngology
Guo Chen, Yami Sun, Ting Yang, Yinliang Wu
A method was developed for the simultaneous determination of flonicamid and its metabolite [N-(4-trifluoromethylnicotinoyl) glycine (TFNG), 4-trifluoromethylnicotinic acid (TFNA) and 4-trifluoromethylnicotinamide (TFNA-AM)] in cucumbers and apples by liquid chromatography-tandem mass spectrometry (LC-MS/MS) with liquid-liquid extraction. The sample was extracted twice with phosphate buffer solution (pH 7.0), and the extract was adjusted to pH 1.5 - 2.0, then an aliquot of the extract (3 mL) was extracted with ethyl acetate...
June 2012: Se Pu, Chinese Journal of Chromatography
Meng Ma, Ping Ping, Jian-Hu Wang, Peng Li, Shi Yang, Jian-Shan Zhu, Hui Lu, Hong-Liang Hu, Zheng Li
OBJECTIVE: To investigate the value and clinical application of the Three-Step Sperm Retrieval method in improving the sperm retrieval rate for non-obstructive azoospermia (NOA) patients. METHODS: Seventy-three NOA patients underwent Three-Step Sperm Retrieval in the following order of procedures: testicular fine needle aspiration (TFNA), testicular sperm extraction (TSE), and microdissection testicular sperm extraction (MD-TSE). The testicular tissue obtained from each step was observed for spermatozoa under the 400-fold inverted microscope...
July 2012: Zhonghua Nan Ke Xue, National Journal of Andrology
S Campainha, M Gonçalves, V Tavares, P Castelões, A Marinho, S Neves
Granulomatosis with Polyangiitis (GPA), which was formerly named Wegener's Granulomatosis (WG) is a systemic disease characterized by necrotizing granulomatous inflammation and vasculitis that primarily involves upper and lower respiratory tract, as well as kidneys. Diagnosing GPA on the basis of transthoracic fine needle aspiration (TFNA) may be problematic, as it can be misdiagnosed as cancer. We describe a patient with a probable GPA which was originally diagnosed as malignancy, but who responded to lung cancer chemotherapy...
January 2013: Revista Portuguesa de Pneumologia
Jerome Jean-Gilles, Andrew H Fischer, Martin H Luu, Christopher L Owens
BACKGROUND: Although thyroid fine-needle aspiration (TFNA) is an excellent test in evaluating thyroid nodules, there are occasionally false negatives (FN). The clinical impact and pathologic features of FN TFNA is understudied in the peer-reviewed literature. METHODS: A cohort of patients with thyroid cancer was separated into those with referring FN TFNA and those with referring true positive (TP) TFNA. Preoperative characteristics, pathologic finding, and clinical outcomes were compared within the 2 groups...
October 25, 2012: Cancer Cytopathology
Yong Xu, Lin-Fei Shou, Yin-Liang Wu
This paper presents a rapid analytical method for the simultaneous determination of flonicamid and its metabolites N-(4-trifluoromethylnicotinoyl) glycine (TFNG), 4-trifluoromethylnicotinic acid (TFNA), and 4-trifluoromethylnicotinamide (TFNA-AM) in vegetables using QuEChERS by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Samples were extracted with acetonitrile. The extract was purified through QuEChERS method with primary secondary amine (PSA) and graphite carbon black (GCB). Then the extract was diluted with 0...
September 23, 2011: Journal of Chromatography. A
Sung Woo Lee, Jeong-Heui Choi, Soon-Kil Cho, Hyun-A Yu, A M Abd El-Aty, Jae-Han Shim
This study describes a new QuEChERS method referred to as the dry ice-partitioning QuEChERS method. This current method can be differentiated from the other QuEChERS methods in the sense that it uses dry ice rather than salts or buffers to extract and partition pesticides in the first extraction step. The dry ice-partitioning QuEChERS method consists of extraction method A (for detection of the acetonitrile layer) and extraction method B (for detection of both acetonitrile and aqueous layers). The extraction efficiency was then compared with the citrate-buffering QuEChERS method by means of recovery...
July 15, 2011: Journal of Chromatography. A
C Stelletta, N S Juyena, D Ponce Salazar, J Ruiz, G Gutierrez
Testicular fine needle aspiration (TFNA) has proven to be a simple and minimally invasive procedure, which allows assessments of cytological parameters of seminiferous epithelium/tubules more accurately in a short time. Though this technique does not cause negative effects on sperm quality or any damage to testicular tissue, its use is very limited in male animal infertility diagnostics. Report on the use of this technique in South American Camelids (SAC) is very limited. Therefore, the aim of this study was to evaluate the efficacy of TFNA for identification of different testicular cells and cell indices, and their correlation with that of impression cytology...
May 2011: Animal Reproduction Science
S Romagnoli, P Bonaccini, C Stelletta, A Garolla, M Menegazzo, C Foresta, A Mollo, C Milani, D Gelli
Clinical investigation of canine testicular function is complicated by the difficulty in the evaluation of seminiferous tubules. Until recently, testicular biopsy was the only diagnostic option for dogs with persistent oligo/azoospermia. In human andrology, testicular fine needle aspiration (TFNA) is currently considered a useful method in the evaluation of azoospermia and severe oligozoospermia, and has long replaced classical biopsy to evaluate spermatogenesis. In order to verify its diagnostic efficacy for the clinical approach to canine oligo- or azoospermia, TFNA was performed in seven adult (two oligozoospermic and five azoospermic) dogs...
July 2009: Reproduction in Domestic Animals
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