B I Liubimov, V A Markin, V S Mitrofanov, R P Porfir'eva, P A Sharov
Tests were set up on rats, guinea pigs and dogs to look into the cronic toxicity of nonachlazine, an effective antianginal agent, used for a space of 6 months in doses of 10 and 35 mg/kg, by far superior to the ones effectively employed clinically. The results of hematological, morphological and biochemical investigations bear evidence to a low toxicity of nonachlozine, which gives good reason to presume the drug to be safe for the use in medical practice.
May 1977: Farmakologiia i Toksikologiia