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https://read.qxmd.com/read/38058721/the-effect-of-therapeutic-exercise-in-the-prevention-of-lymphoedema-secondary-to-breast-cancer-a-systematic-review
#21
REVIEW
Laura Tendero-Ruiz, Rocío Palomo-Carrión, Álvaro Megía-García-Carpintero, Soraya Pérez-Nombela, Purificación López-Muñoz, Elisabeth Bravo-Esteban
INTRODUCTION: One of the most frequent complications of breast cancer treatment is lymphoedema (LE), with lymphadenectomy and radiotherapy being the main triggers of this pathology in developed countries. The aim of the study was to determine the efficacy of therapeutic exercise in the prevention of upper limb (UL) lymphoedema evaluated through cirtometry, volumetry, or bioimpedance spectroscopy (BIS) in women after breast cancer removal surgery. MATERIAL AND METHODS: The Pubmed, PEDro, and Cochrane databases were consulted up to May 2020, including randomised clinical trials (RCTs) on therapeutic physical exercise as a possible preventive measure against breast cancer-related lymphoedema (BCRL)...
2023: Archives of Medical Science: AMS
https://read.qxmd.com/read/38057203/clinical-experience-of-axillary-radiotherapy-for-node-positive-breast-cancer
#22
JOURNAL ARTICLE
S Anderson, A L Peters, G Lumsden, A Alhasso, D Cartwright, O O'Brien, H Marashi
AIMS: Patients with breast cancer who have positive lymph nodes are currently recommended axillary node clearance (ANC) or regional nodal irradiation (RNI). ANC is associated with complications such as lymphoedema, brachial plexopathy and shoulder stiffness. The AMAROS Group showed RNI to be non-inferior to ANC with regards to survival and recurrence, and with a better quality of life. We conducted a large real-world population study to show our centre's experience with the use of RNI and to contribute to the current discussion around the management of node-positive breast cancer...
November 28, 2023: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/37995053/functional-changes-in-the-heart-after-sacubitril-valsartan-use-in-5-hemodialysis-patients-with-hypertension-case-report
#23
JOURNAL ARTICLE
Noriko Kuwae
The purpose of this report is to describe the efficacy of sacubitril/valsartan in 5 hemodialysis patients with hypertension, including a patient with heart failure with reduced ejection fraction (HFrEF) and a patient with preserved ejection fraction (HFpEF) focused on the functional changes in the heart. We switched from angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs) to sacubitril/valsartan and compared blood pressure post dialysis, N-terminal pro-brain natriuretic peptide (NT-pro-BNP) levels and the findings of echocardiography for a period of 6 months...
November 23, 2023: CEN Case Reports
https://read.qxmd.com/read/37928646/physiotherapy-practice-in-lymphoedema-in-south-africa-a-survey
#24
JOURNAL ARTICLE
Carys A Rhodes, Corlia Brandt, Monique Keller
BACKGROUND: Lymphoedema is a chronic condition that is increasing in prevalence and requires specialised management to avoid possible life-threatening complications. OBJECTIVES: To describe the perceived knowledge of physiotherapists about lymphoedema and its management, the lymphoedema patient load seen by physiotherapists, and the current treatment approaches of physiotherapists in South Africa when managing lymphoedema. METHOD: A quantitative study using self-administered, online questionnaires were distributed among physiotherapists...
2023: South African Journal of Physiotherapy
https://read.qxmd.com/read/37907364/a-prospective-study-on-skin-and-soft-tissue-infections-a-fact-finding-mission-from-a-tertiary-centre-in-north-india
#25
JOURNAL ARTICLE
Nitin Agarwal, Ashutosh, Ashish Sharma, Arun Gupta
OBJECTIVE: Despite the high prevalence and poor outcome of skin and soft tissue infections (SSTIs), very few studies from India have dealt with the subject. We planned a prospective study of inpatients with SSTIs to study the aetiology, clinical presentation (severity) and outcome of patients with SSTIs in our facility. METHOD: Patients with SSTIs involving >5% body surface area (BSA) and/or systemic signs were admitted to the surgery department of a teaching tertiary level hospital in Delhi, India, and were clinically classified into cellulitis, necrotising soft tissue infections (NSTIs), pyomyositis, and abscess...
November 1, 2023: Journal of Wound Care
https://read.qxmd.com/read/37902114/navigating-changes-a-qualitative-study-exploring-the-health-related-quality-of-life-of-breast-cancer-survivors-during-the-coronavirus-disease-2019-pandemic
#26
JOURNAL ARTICLE
Ka-Huen Yip, Yuk-Chiu Yip, Wai-King Tsui, Chun-Sze Angela Chan, Yuen-Han Mo, Graeme Drummond Smith
AIMS: To explore the impact of the coronavirus disease 2019 pandemic on the health-related quality of life (HRQoL) of breast cancer survivors. DESIGN: We utilized a qualitative descriptive approach to facilitate interviews among 25 participants, all of whom are survivors of breast cancer and have received treatment in Hong Kong within the preceding 3 years. METHODS: Content analysis was performed to understand how patients' HRQoL views and experiences changed during coronavirus disease 2019 pandemic...
October 30, 2023: Journal of Advanced Nursing
https://read.qxmd.com/read/37900657/iatrogenic-breast-lymphoedema-incidence-diagnosis-and-associated-risk-factors
#27
JOURNAL ARTICLE
Mohamed Ibrahim, Hany Habashy, Sherif Monib
While upper limb lymphoedema following breast and axillary surgery is well established in the literature, breast lymphoedema is rarely documented. Our primary objective was to identify risk factors of breast lymphoedema, and our secondary aim was to assess the possibility of using a breast ultrasound scan to assess breast lymphoedema. This study was a case series analysis, including patients who had wide local excision for primary breast cancer treatment between January 2013 and January 2018. Patients' demographics, including age, weight, body mass index (BMI), breast volume, tumour characteristics, and histological findings, were noted...
September 2023: Indian Journal of Surgical Oncology
https://read.qxmd.com/read/37897443/application-of-complete-decongestive-therapy-after-lymphaticovenular-anastomosis-of-the-lower-limb-combined-with-liposuction-a-retrospective-study-research
#28
JOURNAL ARTICLE
Xuchuan Zhou, Gejia Ma, Xi Qi, Aoshuang Qin, Bin Liu
BACKGROUND: Complete decongestive therapy (CDT) is a conservative treatment for lymphedema that combines interventions and lifestyle changes. We evaluated the application of CDT after lymphaticovenular anastomosis (LVA) of the lower limb combined with liposuction. METHODS: A total of 55 patients who underwent LVA of the lower limb combined with liposuction from January 2021 to July 2022 were enrolled in the study. The patients were divided into groups A ( n = 24) and B ( n = 31) according to whether they adhered to CDT treatment during the 12-month follow-up...
October 28, 2023: Phlebology
https://read.qxmd.com/read/37851028/a-dual-clock-driven-model-of-lymphatic-muscle-cell-pacemaking-to-emulate-knock-out-of-ano1-or-ip3r
#29
JOURNAL ARTICLE
Edward J Hancock, Scott D Zawieja, Charlie Macaskill, Michael J Davis, Christopher D Bertram
Lymphatic system defects are involved in a wide range of diseases, including obesity, cardiovascular disease, and neurological disorders, such as Alzheimer's disease. Fluid return through the lymphatic vascular system is primarily provided by contractions of muscle cells in the walls of lymphatic vessels, which are in turn driven by electrochemical oscillations that cause rhythmic action potentials and associated surges in intracellular calcium ion concentration. There is an incomplete understanding of the mechanisms involved in these repeated events, restricting the development of pharmacological treatments for dysfunction...
December 4, 2023: Journal of General Physiology
https://read.qxmd.com/read/37840952/electronic-health-record-wide-association-study-for-atrial-fibrillation-in-a-british-cohort
#30
JOURNAL ARTICLE
Sheng-Chia Chung, Amand F Schmit, Gregory Y H Lip, Rui Providencia
BACKGROUND: Atrial fibrillation (AF) confers a major healthcare burden from hospitalisations and AF-related complications, such as stroke and heart failure. We performed an electronic health records-wide association study to identify the most frequent reasons for healthcare utilization, pre and post new-onset AF. METHODS: Prospective cohort study with the linked electronic health records of 5.6 million patients in the United Kingdom Clinical Practice Research Datalink (1998-2016)...
2023: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/37784349/5-year-results-from-a-prospective-phase-ii-trial-of-ten-fractions-hypofractionated-radiotherapy-in-locally-advanced-breast-cancer
#31
JOURNAL ARTICLE
P Pinnaro, S Takanen, L Marucci, D Giannarelli, P Vici, A Borges Da Silva, G Sanguineti
PURPOSE/OBJECTIVE(S): There is a growing interest for adjuvant loco-regional hypofractionated radiotherapy (Hypo-RT) regimens in patients (pts) undergoing surgery for locally advanced breast cancer (LABC). We report the 5-year results of a phase II study on Hypo-RT targeting the primary and regional lymph nodes in ten fractions (fxs). MATERIALS/METHODS: A schedule of 34 Gy/10 fxs/2 wks to the whole breast/chest wall and to the draining lymph nodes was used; an optional single fraction 8 Gy boost was administered with electrons to the tumor bed in patients who had undergone conservative surgery...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37772973/integrative-medicine-and-self-care-in-the-treatment-of-lymphatic-filariasis-associated-lymphoedema-an-effective-strategy
#32
EDITORIAL
Archana Singal, Kavita Bisherwal
No abstract text is available yet for this article.
September 29, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37757820/assessment-and-management-of-upper-limb-lymphoedema-in-advanced-disease-a-case-study
#33
JOURNAL ARTICLE
Amy Duffield
Lymphoedema is thought to affect around 200 000 people in the UK (NHS England, 2023). Secondary lymphoedema is a relatively common complication of cancer and cancer treatment, and in advanced disease it may present a challenging issue for community nursing staff caring for patients approaching the end of their lives. In this article, a case study considers the assessment and treatment of upper limb lymphoedema in a patient with advanced metastatic breast cancer. Management of this complex and distressing condition requires holistic assessment and collaborative care planning with the patient and their wider care team, including onward referral to specialist lymphoedema and palliative care services...
October 1, 2023: British Journal of Community Nursing
https://read.qxmd.com/read/37757816/the-role-of-aromatase-inhibitors-in-slim-women-with-breast-cancer-related-lymphoedema-a-reflective-case-series
#34
JOURNAL ARTICLE
Clare Anvar
BACKGROUND: This case series follows the reflective processes undertaken, when five slim women presented with reactive oedemas of the forearm and hand, that did not respond to usual therapy. AIM: To raise awareness about Aromatase Inhibitor (AI), Letrozole. METHODS: Possible causes, including Cyclin-Dependent Kinase 4 and 6 (CDK4/6) inhibitors, Ribociclib and Axillary Web Syndrome, were explored and reviewed, and potential effective treatment options were then sought...
October 1, 2023: British Journal of Community Nursing
https://read.qxmd.com/read/37757815/overcoming-lymphorrhoea-a-step-to-achieve-a-better-life-with-lymphoedema
#35
JOURNAL ARTICLE
Francesca Ramadan
Lymphorrhoea-otherwise known as 'wet' or 'leaky' legs-is an increasingly common condition that many community nurses will encounter in their daily practice; however, until relatively recently, evidence-based literature on its management was limited, and treatment modalities only tackled the symptoms instead of addressing the cause. In this article, Francesca Ramadan highlights the devastating impact of this condition, and the resources available to community practitioners to assist their patients to live well with lymphoedema...
October 1, 2023: British Journal of Community Nursing
https://read.qxmd.com/read/37706409/long-term-outcomes-of-vulvar-or-vaginal-cancer-patients-undergoing-laparoendoscopic-single-site-inguinal-lymphadenectomy
#36
JOURNAL ARTICLE
Jing-Yun Xu, Tian-Xiang Yu, Xiao-Ming Guan, Bo Ding, Mu-Lan Ren, Yang Shen
INTRODUCTION: Laparoendoscopic single-site inguinal lymphadenectomy (LESS-IL), a minimally invasive technique, has been reported in patients with vulvar or vaginal cancer regarding its safety and feasibility. However, the long-term outcomes, especially oncologic outcomes, are still lacking. We aimed to evaluate the long-term outcomes of LESS-IL to confirm its safety further. PATIENTS AND METHODS: Data were prospectively collected from patients with vulvar or vaginal cancer who underwent LESS-IL at our institution between July 2018 and June 2021...
July 5, 2023: Journal of Minimal Access Surgery
https://read.qxmd.com/read/37648875/evaluating-the-effects-of-lymphoedema-management-strategies-on-functional-status-and-health-related-quality-of-life-following-treatment-for-head-and-neck-cancer-a-systematic-review
#37
REVIEW
Lauren J Mullan, Nicole E Blackburn, Jackie Gracey, Lynn Dunwoody, Jill Lorimer, Cherith J Semple
PURPOSE: Patients living with head and neck lymphoedema (HNL) after completion of head and neck cancer (HNC) often can experience long-term functional challenges and overall poorer health-related quality of life (HRQOL). This systematic review aims to explore components of effective HNL interventions through identification and synthesising literature on existing HNL management interventions. METHODS: Five electronic databases (MEDLINE via Ovid and PubMed, CINAHL, CENTRAL, and Scopus) were systematically searched using Medical Subject Headings and free text, as well as citation tracking and Google Scholar for grey literature...
August 30, 2023: Journal of Cancer Survivorship: Research and Practice
https://read.qxmd.com/read/37615507/self-care-treatment-for-lymphoedema-of-lymphatic-filariasis-using-integrative-medicine
#38
JOURNAL ARTICLE
Saravu R Narahari, Madhur G Aggithaya, Terence J Ryan, Kunnathody Muralidharan, Peter J Franks, Christine Moffatt, Peter S Mortimer
BACKGROUND: Lymphatic Filariasis (LF) is a neglected tropical disease presenting mainly as lymphoedema (elephantiasis). LF is not effectively treated. Integrative Medicine treatment (IM) for lymphoedema uses a combination of Indian traditional medicine, ayurveda, alongside yoga exercises, compression therapy, antibiotics and antifungals, providing a useful combination where resources are limited and different practices are in use. OBJECTIVES: To assess the effectiveness of the IM in the existing clinical practice of lower limb lymphoedema management and to determine whether the treatment outcomes aligned with the WHO's global goal of LF...
August 24, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37548514/advances-in-and-applications-of-imaging-and-radiomics-in-head-and-neck-cancer-survivorship
#39
JOURNAL ARTICLE
Laurelie R Wishart, Elizabeth C Ward, Graham Galloway
PURPOSE OF REVIEW: Radiological imaging is an essential component of head/neck cancer (HNC) care. Advances in imaging modalities (including CT, PET, MRI and ultrasound) and analysis have enhanced our understanding of tumour characteristics and prognosis. However, the application of these methods to evaluate treatment-related toxicities and functional burden is still emerging. This review showcases recent literature applying advanced imaging and radiomics to the assessment and management of sequelae following chemoradiotherapy for HNC...
August 7, 2023: Current Opinion in Otolaryngology & Head and Neck Surgery
https://read.qxmd.com/read/37528487/long-term-outcomes-of-sbrt-for-psma-pet-detected-oligometastatic-prostate-cancer
#40
JOURNAL ARTICLE
Riche Mohan, A Kneebone, T Eade, E Hsiao, L Emmett, Christopher Brown, J Hunter, G Hruby
BACKGROUND: Oligometastatic disease in prostate cancer (PCa) is a challenging clinical scenario encountered more frequently with the widespread adoption of PSMA-PET. SBRT aims to defer androgen deprivation and may deliver sustained biochemical failure (BF) free survival in selected patients. Little long-term data is currently available regarding the effectiveness of this approach. METHODS: A retrospective single institution study of PSMA-PET directed SBRT without initial ADT for oligo-metachronous PCa...
August 1, 2023: Radiation Oncology
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