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lymphoedema treatment

M Co, A Lee, A Kwong
AIMS: Secondary angiosarcoma is known to be associated with lymphoedema or radiation after cancer treatment. This systematic review aims to evaluate the clinical features and outcomes of secondary angiosarcoma commonly arising after breast cancer treatment. MATERIALS AND METHODS: A systematic review was carried out according to the PRISMA protocol. Medline, EMBASE, CINAHL and Cochrane databases were searched for English articles to April 2018 with predefined strategy...
February 6, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
Janet Douglass, Lukah Dykes, Louise Kelly-Hope, Susan Gordon, Peter Leggat, Ni Ni Aye, San San Win, Tint Wai, Yi Yi Win, Thet Wai Nwe, Patricia Graves
OBJECTIVES: This longitudinal comparative study investigated the effect of preventive chemotherapy (PC) on covert tissue changes associated with lymphatic filariasis (LF) among young people living in an LF-endemic area in Myanmar. METHODS: Tissue compressibility and extracellular free fluid in the lower limbs of people aged 10 - 21 years were measured using Indurometry and bio-impedance spectroscopy (BIS). Baseline measures were taken in October 2014, annual mass drug administration (MDA) of PC was delivered in December and in March 2015, and further PC was offered to LF-positive cases who had missed MDA...
January 31, 2019: Tropical Medicine & International Health: TM & IH
Linnea Waldorff Lund, Gunn Ammitzbøll, Dorte Gilså Hansen, Elisabeth Anne Wreford Andersen, Susanne Oksbjerg Dalton
BACKGROUND: The purpose of the study was to examine adherence and identify patient- and treatment-related factors associated with adherence to a 20-week combined supervised and home-based progressive resistance training program in women treated for breast cancer. METHODOLOGY: The study population consisted of the intervention group in a randomized clinical trial examining the effect of resistance exercise on lymphoedema prevention (n = 82). The full program lasted 50 weeks, with an initial 20 weeks combined supervised and home-based exercise followed by 30 weeks self-administered exercise...
January 30, 2019: Acta Oncologica
Ana N M B M Pinho, Joana M M Ferreira, Alexandre F L Carneiro
This is the first case report of upper extremity lymphoedema caused by a thyroid tumour. An 87 year old female patient with grade 3 lymphoedema of the upper right extremity was admitted. The lymphoedema had developed over the course of two years. Investigation identified a thyroid tumour, which compressed the mediastinal structures at the right superior thoracic outlet, causing venous congestion, oedema, and lymphoedema. The patient underwent thyroidectomy which markedly improved the lymphatic oedema. Resolution of the compression mechanism was an effective treatment, despite the severity and chronicity of the initial presentation...
2019: EJVES Short Reports
Kevork Karakashian, Cheryl Pike, Raoul van Loon
This study aims to use computational methods for elucidating the effect of limb shape on subgarment and subcutaneous pressures, stresses and strains. A framework was built that generates computational models from 3D arm scans using a depth sensing camera. Finite Element Analysis (FEA) was performed on the scans taken from 23 lymphoedema patients. Subgarment pressures were calculated based on local curvature for each patient and showed a large variability of pressure across each arm. Across the cohort an average maximum subgarment pressure of 5100 Pa was found as opposed to an intended garment pressure of 2500 Pa...
December 19, 2018: Journal of Biomechanics
Konstantin Christoph Koban, Virginia Titze, Lucas Etzel, Konstantin Frank, Thilo Schenck, Riccardo Giunta
BACKGROUND: Tape measures continue to be used for the diagnosis and evaluation of lipoedema and lymphoedema in the clinical routine. Extremity volumes are calculated based on standardised circumferential measurements. Other volume measurements such as water displacement are not applied on a regular basis. This study aimed to evaluate a 3D scanner as an alternative and reproducible tool to objectively measure the volumes of the lower extremity. PATIENTS, MATERIALS AND METHOD: We used a commercially available 3D scanner, the Artec Eva® , to perform 3D scans of the lower extremities on 20 subjects and calculated the volume using the appropriate software...
December 2018: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
Katharina Zetzmann, Ingo Ludolph, Raymund E Horch, Anja Miriam Boos
Lipoedema is a progressive disease, which predominantly affects women. It is characterised by circumferential growth, with increase in fat tissue of the extremities, and can lead to oedema. In contrast, the lymphoedema is defined by a specific lymphatic drainage disorder and can lead to fibrosis of the surrounding connective tissue. While lipoedema is diagnosed through clinical symptoms and diagnostic imaging can usually only be used to rule out comorbidities, lymphatic drainage disorder can be visualised using imaging methods...
December 2018: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
Vicenta Pujol-Blaya, Sira Salinas-Huertas, M Luisa Catasús, Teresa Pascual, Roser Belmonte
OBJECTIVE: To compare the effectiveness of a precast adjustable compression system with that of multilayered compression bandages in the treatment of breast cancer-related lymphoedema. DESIGN: Multicenter, randomized, single-blind parallel-group clinical trial. SETTING: The rehabilitation services of four general university hospitals. SUBJECTS: Patients with upper limb breast cancer-related lymphoedema. INTERVENTIONS: All the patients received manual lymphatic drainage, followed by a precast adjustable compression system or multilayered compression bandages, according to the group allocation...
January 4, 2019: Clinical Rehabilitation
Nicky Kramer, Jo Ramjith, Delva Shamley
PURPOSE: Breast cancer is the most frequently diagnosed cancer and leading cause of cancer death among women, representing a considerable public health burden in South Africa and other low-middle income countries. Short- and long-term complications of these treatments include shoulder morbidities such as pain, decreased range of motion, tightness, weakness, pain, numbness and lymphoedema and may be present for up to 6 years post-treatment. An understanding of baseline demographic and clinical risk factors can guide rehabilitation and management strategies for high-risk patients...
November 19, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Hiroo Suami, Louise Koelmeyer, Helen Mackie, John Boyages
Upper extremity lymphoedema after axillary node dissection is an iatrogenic disease particularly associated with treatment for breast or skin cancer. Anatomical studies and lymphangiography in healthy subjects identified that axillary node dissection removes a segment of the lymphatic drainage pathway running from the upper limb to the sub-clavicular vein, creating a surgical break. It is reasonable to infer that different patterns of lymphatic drainage may occur in the upper limb following surgery and contribute to the various presentations of lymphoedema from none to severe...
December 2018: Surgical Oncology
Wei Wang, Rachel Ward, Dan Jia, Simon Ashworth, Edgar Estoesta, Trevor Moodie, Verity Ahern, Kirsty Stuart, Nicholas Ngui, James French, Elisabeth Elder, David Farlow
BACKGROUND: Lymphoedema of the arm following axillary surgery or radiotherapy remains a significant side effect affecting some women after breast cancer treatment. Axillary reverse mapping (ARM) is a technique used to identify the lymph node draining the arm (ARM node). Our study aim was to examine the location of the ARM nodes in relation to target volumes and treatment fields for breast cancer radiotherapy. MATERIALS AND METHODS: Eighteen breast cancer patients underwent lymphoscintigraphy of contralateral arm (left 10, right 8) and SPECT CT scan on a research study...
November 13, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
Lavanya Anandan, Aza Mohammed
Introduction: Buried penis is a condition that causes the penis to become hidden beneath the skin. It has a significant impact on quality of life and can present in a variety of ways, with lower urinary tract symptoms and erectile dysfunction being common. Whilst there are several causes, obesity is the most common in adults. Due to the burden that obesity is increasingly presenting to healthcare, buried penis may become more common in the future.The purpose of this article is to provide an overview of the causes, presentation and surgical management of this condition in adults...
2018: Central European Journal of Urology
Mette Tambour, Marianne Holt, Anette Speyer, Robin Christensen, Bibi Gram
BACKGROUND: We investigated the comparability of Complete Decongestive Therapy (CDT) including manual lymphatic drainage (MLD) vs. without MLD in the management of arm lymphoedema in patients with breast cancer. METHODS: Patients randomised into either treatment including MLD (T+MLD) or treatment without MLD (T-MLD) received treatment 2×weekly for 4 weeks. The primary outcome was the volume reduction (%) of arm lymphoedema at 7-month follow-up. The secondary outcomes were volume reduction after the end of treatment, circumference of the arm, patient experience of heaviness and tension, and health status...
November 2018: British Journal of Cancer
A A Khan, I Hernan, J A Adamthwaite, K W D Ramsey
BACKGROUND: Breast cancer-related lymphoedema (BCRL) presents a significant healthcare burden and adversely affects quality of life of breast cancer survivors. A prospective feasibility study was performed on lymphaticovenous anastomosis (LVA) for the treatment of BCRL. METHODS: Patients with BCRL underwent near-infrared spectroscopy with indocyanine green lymphatic mapping to identify suitable lymphatic channels for LVA. End-to-end anastomoses to subdermal venules were performed and patients recommenced compression garment therapy (CGT) after surgery...
January 2019: British Journal of Surgery
Pauline McGee, David Alex Munnoch
OBJECTIVE: To evaluate outcomes in patients with gynaecological cancer related lymphoedema treated with liposuction. METHODS: A prospective analysis of 21 patients who underwent liposuction followed by compression therapy for chronic unilateral lower limb lymphoedema with up to 8 years follow up was performed. RESULTS: Duration of lymphoedema prior to liposuction ranged from 4 to 28 years (mean 15.2 years). The mean age at time of liposuction was 52 years (range 37-67)...
October 4, 2018: Gynecologic Oncology
Garry Cooper-Stanton
Chronic oedema (CO) and lymphoedema (LO) are long-term conditions that can become more complicated or are more likely to develop with age. The ageing process can involve alterations in the structures that support the normal function of the lymphatic system or put it at greater risk of damage. The main three components (skin care, exercise and compression therapy) within the management of CO/LO can become more difficult to apply with age. This is because of reduced healing rates, decreased cardiovascular capacity and deterioration in vascular and arterial structures...
October 1, 2018: British Journal of Community Nursing
Natalie Lee, Sue Lawrance
The aim of compression therapy is to apply pressure on the skin and underlying structures to counteract the force of gravity, supporting venous and lymphatic function, to prevent or minimise oedema in the affected tissues. Compression therapy to manage lymphoedema is supported by a plethora of research, as it helps to increase the velocity of flow and lymphatic contraction of the lymphatic collecting vessels. This encourages drainage to the route of the limb, which increases fluid drainage from the tissues into the lymphatics...
October 1, 2018: British Journal of Community Nursing
Viviana Galimberti, Bernard F Cole, Giuseppe Viale, Paolo Veronesi, Elisa Vicini, Mattia Intra, Giovanni Mazzarol, Samuele Massarut, Janez Zgajnar, Mario Taffurelli, David Littlejohn, Michael Knauer, Carlo Tondini, Angelo Di Leo, Marco Colleoni, Meredith M Regan, Alan S Coates, Richard D Gelber, Aron Goldhirsch
BACKGROUND: We previously reported the 5-year results of the phase 3 IBCSG 23-01 trial comparing disease-free survival in patients with breast cancer with one or more micrometastatic (≤2 mm) sentinel nodes randomly assigned to either axillary dissection or no axillary dissection. The results showed no difference in disease-free survival between the groups and showed non-inferiority of no axillary dissection relative to axillary dissection. The current analysis presents the results of the study after a median follow-up of 9·7 years (IQR 7·8-12·7)...
October 2018: Lancet Oncology
Jodie L Nixon, Amanda E Pigott, Bena Cartmill, Jane Turner, Jennifer Fleming, Sandro V Porceddu
PURPOSE: This study aimed to examine the course and nature of distress and quality of life (QoL) during and after head and neck lymphoedema (HNL) treatment in people who developed HNL following treatment for head and neck cancer (HNC). METHODS: This study (n = 10) used a mixed method explanatory design to explore distress associated with HNL. Component 1 used a prospective repeated measures design to examine distress during a 22-week HNL program. Component 2 used a qualitative interview approach to understand the patient experience of distress after completion of HNL treatment...
August 2018: Oral Oncology
Judith Whatley, Rachael Street, Sally Kay
BACKGROUND AND PURPOSE: An estimated 1 in 5 women surviving breast cancer will go on to develop breast cancer related lymphoedema (BCRL). There is a gap in the literature capturing experiences of people living with BCRL who use complementary therapies. MATERIALS AND METHODS: Data were collected from 26 participants via a semi-structured interview. Questioning centred around their personal experiences of living with lymphoedema, and their use of reflexology lymphatic drainage...
August 2018: Complementary Therapies in Clinical Practice
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