Xingjie Wang, Changjun Liu, Xuqi Li, Tianli Shen, Jie Lian, Jing Shi, Zhengdong Jiang, Guanglin Qiu, Yuanbo Wang, Er Meng, Guangbing Wei
OBJECTIVE: Abdominal wall hernias are common abdominal diseases, and effective hernia repair is challenging. In clinical practice, synthetic meshes are widely applied for repairing abdominal wall hernias. However, postoperative complications, such as inflammation and adhesion, are prevalent. Although biological meshes can solve this problem to a certain extent, they face the problems of heterogeneity, rapid degradation rate, ordinary mechanical properties, and high-cost. Here, a novel electrospinning mesh composed of polylactic acid and silk fibroin (PLA-SF) for repairing abdominal wall hernias was manufactured with good physical properties, biocompatibility and low production cost...
February 2024: Materials today. Bio