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https://read.qxmd.com/read/30771780/improved-survival-of-glioblastoma-patients-treated-at-academic-and-high-volume-facilities-a-hospital-based-study-from-the-national-cancer-database
#1
Ping Zhu, Xianglin L Du, Jay-Jiguang Zhu, Yoshua Esquenazi
OBJECTIVEThe present study was designed to explore the association between facility type (academic center [AC] vs non-AC), facility volume (high-volume facility [HVF] vs low-volume facility [LVF]), and outcomes of glioblastoma (GBM) treatment.METHODSBased on the National Cancer Database (NCDB), GBM patients were categorized by treatment facility type (non-AC vs AC) and volume [4 categories (G1-G4): < 5.0, 5.0-14.9, 15.0-24.9, and ≥ 25.0, cases/year]. HVF was defined based on the 90th percentile of annual GBM cases (≥ 15...
February 15, 2019: Journal of Neurosurgery
https://read.qxmd.com/read/30771769/correlation-of-perioperative-risk-scores-with-hospital-costs-in-neurosurgical-patients
#2
Sasha Vaziri, Joseph M Abbatematteo, Max S Fleisher, Alexander B Dru, Dennis T Lockney, Paul S Kubilis, Daniel J Hoh
OBJECTIVEThe American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) online surgical risk calculator uses inherent patient characteristics to provide predictive risk scores for adverse postoperative events. The purpose of this study was to determine if predicted perioperative risk scores correlate with actual hospital costs.METHODSA single-center retrospective review of 1005 neurosurgical patients treated between September 1, 2011, and December 31, 2014, was performed. Individual patient characteristics were entered into the NSQIP calculator...
February 15, 2019: Journal of Neurosurgery
https://read.qxmd.com/read/30771640/socioeconomic-differences-in-the-associations-between-diabetes-and-hospital-admission-and-mortality-among-older-adults-in-europe
#3
Beatriz Rodríguez-Sánchez, David Cantarero-Prieto
The aim of this study is to explain the trends in socioeconomic inequality and diabetes outcomes in terms of hospital admission and death in old European people. The sample includes 73,301 individuals, across 16 European countries taken from the Survey of Health, Ageing and Retirement in Europe (SHARE). People being diagnosed of diabetes were more likely to be admitted to hospital than those without diabetes, although its effect dropped after controlling for clinical and functional complications. Largest asscociations were observed in women, people aged 50-65 years old, with medium educational level and medium household income...
January 17, 2019: Economics and Human Biology
https://read.qxmd.com/read/30771607/the-effects-of-a-childbirth-preparation-course-on-birth-outcomes-among-nulliparous-jordanian-women
#4
Reem Hatamleh, Sanaa Abujilban, Asma'a Shaker AbdelMahdi AbuAbed, Sawsan Abuhammad
OBJECTIVE: This study aimed to examine the effectiveness of a childbirth preparation course on birth outcomes among nulliparous Jordanian women. DESIGN: A randomized control trial pre-test/post-test design was used to assess the effects of a childbirth preparation course conducted in a military hospital in Amman, Jordan from 1 July to 15 September 2016. A total of 133 low-risk nulliparous women were recruited and randomly assigned to either (1) a control group who received standard care in antenatal clinics or (2) an intervention group who received standard care in antenatal clinics as well as a childbirth preparation course specifically designed for the purpose of this study...
February 7, 2019: Midwifery
https://read.qxmd.com/read/30771606/mobile-obstetric-and-neonatal-simulation-based-skills-training-in-india
#5
Arunaz Kumar, Tarundeep Singh, Utkarsh Bansal, Jaivir Singh, Stacey Davie, Atul Malhotra
BACKGROUND: The developing world has a significantly high risk of women and babies dying during childbirth. Interprofessional simulation training has improved birth practices and outcomes by impacting clinical and non-technical skills like communication, teamwork, leadership and effective use of resources. While these programs have become a training requirement in many high-income countries, they have not been widely introduced in the low-income, low-resource settings. QUESTION: To explore the use of a structured obstetric and neonatal emergency simulation training program in India...
February 7, 2019: Midwifery
https://read.qxmd.com/read/30771556/stroke-occurrence-while-on-antiplatelet-therapy-may-predict-atrial-fibrillation-detected-after-stroke
#6
Cheng-Yang Hsieh, Cheng-Han Lee, Sheng-Feng Sung
BACKGROUND AND AIMS: Stroke occurrence while on antiplatelet therapy, i.e., a breakthrough stroke, is often conveniently attributed to antiplatelet resistance. However, undetected paroxysmal atrial fibrillation (AF) may underlie breakthrough strokes. We hypothesized that a breakthrough stroke may be a clinical marker for patients at risk of having AF detected after stroke (AFDAS). METHODS: Consecutive patients without known AF hospitalized for ischemic stroke between 2000 and 2013 were identified from nationwide claims data...
January 24, 2019: Atherosclerosis
https://read.qxmd.com/read/30771053/assessing-sustainable-effectiveness-of-the-adjustment-mechanism-of-a-ubiquitous-clinic-recommendation-system
#7
Min-Chi Chiu, Tin-Chih Toly Chen
Advances in computer and communication technologies have engendered opportunities for developing an improved ubiquitous health care environment. One of the crucial applications is a ubiquitous clinic recommendation system, which entails recommending a suitable clinic to a mobile patient based on his/her location, hospital department, and preferences. However, patients may not be willing or able to express their preferences. To overcome this problem, some ubiquitous clinic recommendation systems mine the historical data of patients to learn their preferences, and they apply an algorithm to adjust the recommendation algorithm after receiving more patient data...
February 15, 2019: Health Care Management Science
https://read.qxmd.com/read/30770978/determinants-of-disease-severity-among-patients-with-atopic-dermatitis-association-with-components-of-the-atopic-march
#8
Jesper Grønlund Holm, Tove Agner, Maja-Lisa Clausen, Simon Francis Thomsen
We aimed to explore the association of key clinical characteristics with disease severity in atopic dermatitis (AD) and its relation to components of the atopic march in a large hospital cohort. Outpatients with AD referred to the Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark, between January 2012 and December 2017, were compared based on disease severity (SCORAD); mild (< 25), moderate (25-50) and severe (> 50). A total of 470 AD patients were included: 122 small children (< 4 years of age), 103 children/adolescents (age 4-15 years) and 245 adults (> 15 years of age)...
February 15, 2019: Archives of Dermatological Research
https://read.qxmd.com/read/30770955/a-mixed-psychiatric-and-somatic-care-unit-for-trauma-patients-10-years-of-experience-in-an-urban-level-i-trauma-center-in-the-netherlands
#9
Lisette Dekker, Hansje M Heller, Jessica E van der Meij, Annelies E J Toor, Leo M G Geeraedts
BACKGROUND: A medical-psychiatric unit (MPU) is a special ward where staff is trained in caring for patients with psychiatric or behavioural problems that need hospitalisation for physical health problems. It is well known that these patients are at higher risk of complications and have a longer length of stay resulting in higher costs than patients without psychiatric comorbidity. The objective of this study was to analyse the trauma patient population of the first 10 years of existence of the MPU in a level I trauma center...
February 15, 2019: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/30770926/a-pregnancy-cohort-to-study-multidimensional-correlates-of-preterm-birth-in-india-study-design-implementation-and-baseline-characteristics-of-the-participants
#10
Shinjini Bhatnagar, Partha P Majumder, Dinakar M Salunke
Globally, preterm birth is a major public health problem. In India, 3.6 million of the 27 million infants born annually are preterm. Risk stratification of women based on multidimensional risk factors assessed during pregnancy is critical for prevention of preterm birth. A cohort study of pregnant women was initiated in May 2015 at the civil hospital in Gurugram, Haryana, India. Women are enrolled within 20 weeks of gestation and are followed until delivery and once postpartum. The objectives are to identify clinical, epidemiologic, genomic, epigenomic, proteomic, and microbial correlates; discover molecular-risk markers by using an integrative -omics approach; and generate a risk-prediction algorithm for preterm birth...
February 16, 2019: American Journal of Epidemiology
https://read.qxmd.com/read/30770882/health-literacy-of-parents-of-very-preterm-infants-at-nicu-admission-and-discharge-a-prospective-cohort-study
#11
Elizabeth Enlow, Megan M Gray, Sara Wallace-Keeshen, Jo Ann D'Agostino, Soraya Abbasi, Scott A Lorch
OBJECTIVE: To determine the prevalence of limited health literacy in parents of infants born ≤32 and 0/7 weeks and if health literacy changes during hospitalization. STUDY DESIGN: Multi-site, prospective cohort study measuring health literacy using the Parent Health Literacy Activities Test, which estimates caregivers' ability to complete tasks such as reading prescription labels and preparing bottles. Data were analyzed using parametric and nonparametric comparison tests and multivariable regression to control for confounders...
February 15, 2019: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/30770765/health-related-quality-of-life-in-systemic-sclerosis-compared-with-other-rheumatic-diseases-a-cross-sectional-study
#12
Eun Hye Park, Vibeke Strand, Yoon Jeong Oh, Yeong Wook Song, Eun Bong Lee
BACKGROUND: Systemic sclerosis (SSc) is a rare autoimmune disease characterized by fibrosis of the skin and the involvement of multiple internal organs. Previous studies reported poorer health-related quality of life (HRQoL) in patients with SSc compared with the general population. However, very little is known about how HRQoL in SSc patients compares with that in patients with other systemic autoimmune diseases, such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Sjogren's syndrome (SjS)...
February 15, 2019: Arthritis Research & Therapy
https://read.qxmd.com/read/30770753/repeat-hepatectomy-with-systemic-chemotherapy-might-improve-survival-of-recurrent-liver-metastasis-from-colorectal-cancer-a-retrospective-observational-study
#13
Hiroshi Matsuoka, Zenichi Morise, Chihiro Tanaka, Takahiro Hayashi, Yoshiaki Ikeda, Koutarou Maeda, Koji Masumori, Yoshikazu Koide, Hidetoshi Katsuno, Yoshinao Tanahashi, Sanae Nakajima, Tsunekazu Hanai, Yutaro Kato, Atsushi Sugioka, Ichiro Uyama
BACKGROUND: Although hepatectomy for metastatic colorectal cancer (mCRC) prolongs survival in up to 40% of people, recurrence rates approach 70%. We used a multidisciplinary approach to treat recurrent liver metastases, including chemotherapy, surgery, and palliative care. On the other hand, development of chemotherapeutic agents is remarkable and improves long-term survival. However, whether chemotherapy and repeat hepatectomy combination therapy improve survival or not is still unclear...
February 15, 2019: World Journal of Surgical Oncology
https://read.qxmd.com/read/30770749/reproductive-cancer-risk-factors-among-relatives-of-cancer-patients-in-a-tertiary-oncology-center
#14
Nooria Atta, Saadettin Kilickap, Deniz Yuce, Mutlu Hayran
BACKGROUND: The aim of this study was to evaluate the prevalence of some gynecological cancer risk factors in a population of female relatives of cancer patients in Hacettepe University Oncology Hospital. Additionally, what are the levels of the women's awareness /behavior toward available screening tools? METHODS: An individual cancer risk assessment questionnaire has been developed in the Department of Preventive Oncology, which questions the medical history, health behaviors and cancer awareness, as well as their behavior toward available cancer screening tools...
February 15, 2019: BMC Cancer
https://read.qxmd.com/read/30770708/convergence-of-virulence-and-mdr-in-a-single-plasmid-vector-in-mdr-klebsiella-pneumoniae-st15
#15
Margaret M C Lam, Kelly L Wyres, Ryan R Wick, Louise M Judd, Aasmund Fostervold, Kathryn E Holt, Iren Høyland Löhr
BACKGROUND: MDR and hypervirulence (hv) are typically observed in separate Klebsiella pneumoniae populations. However, convergent strains with both properties have been documented and potentially pose a high risk to public health in the form of invasive infections with limited treatment options. OBJECTIVES: Our aim was to characterize the genetic determinants of virulence and antimicrobial resistance (AMR) in two ESBL-producing K. pneumoniae isolates belonging to the international MDR clone ST15...
February 15, 2019: Journal of Antimicrobial Chemotherapy
https://read.qxmd.com/read/30770541/high-hydrostatic-pressure-processing-better-preserves-the-nutrient-and-bioactive-compound-composition-of-human-donor-milk
#16
Michael A Pitino, Sharon Unger, Alain Doyen, Yves Pouliot, Susanne Aufreiter, Debbie Stone, Alex Kiss, Deborah L O'Connor
BACKGROUND: When mother's milk is insufficient, pasteurized human donor milk (DM) is the recommended supplement for hospitalized very-low-birth-weight infants. The current method of pasteurization (Holder, 62.5°C, 30 min) negatively affects heat-sensitive nutrients and bioactive proteins. OBJECTIVES: Objectives of this study were to compare changes in DM composition after thermal pasteurization (Holder and flash-heating) and nonthermal methods [UV-C irradiation and high hydrostatic pressure (HHP)]...
February 15, 2019: Journal of Nutrition
https://read.qxmd.com/read/30770324/neuropsychiatric-symptoms-in-tanzanian-hiv-infected-children-receiving-long-term-efavirenz-treatment-a-multicentre-cross-sectional-observational-study
#17
Lisa Van de Wijer, Deborah N Mchaile, Quirijn de Mast, Blandina T Mmbaga, Nanda N J Rommelse, Ashanti Duinmaijer, André J A M van der Ven, Arnt F A Schellekens, Grace D Kinabo
BACKGROUND: Efavirenz is commonly prescribed for children with HIV infection, yet little is known about risks of neuropsychiatric side-effects. We aimed to compare competence (social involvement, activities, and school performance) and psychopathology (internalising and externalising problems), cognitive performance (intelligence and working memory), and adherence in Tanzanian children on an efavirenz-based versus a non-efavirenz-based regimen. METHODS: In this multicentre, cross-sectional, observational study, we included consecutive children (aged 6-12 years) with HIV infection, on combination antiretroviral therapy (cART) for at least 6 months, and with viral loads of less than 1000 copies per mL from HIV care clinics of three primary health facilities and three referral hospitals in Moshi, Kilimanjaro, Tanzania...
February 12, 2019: Lancet HIV
https://read.qxmd.com/read/30770302/thermal-cautery-assisted-circumcision-and-principles-of-its-use-to-decrease-complication-rates
#18
O Akyüz, M N Bodakçi, A H Tefekli
INTRODUCTION: Circumcision is one of the most frequently applied surgical procedures all over the world and a number of techniques and devices have been described concerning its method. Especially in developing countries where circumcision has been performed intensively under local anaesthesia, the thermocautery device developed to perform circumcisions in a short time and safely has found a widespread application. OBJECTIVE: We aim to share our experiences concerning application principles of the thermocautery device so as to be able to achieve better cosmetic results with lower complication rates...
January 19, 2019: Journal of Pediatric Urology
https://read.qxmd.com/read/30770291/stereotactic-ablative-radiotherapy-versus-standard-radiotherapy-in-stage-1-non-small-cell-lung-cancer-trog-09-02-chisel-a-phase-3-open-label-randomised-controlled-trial
#19
David Ball, G Tao Mai, Shalini Vinod, Scott Babington, Jeremy Ruben, Tomas Kron, Brent Chesson, Alan Herschtal, Marijana Vanevski, Angela Rezo, Christine Elder, Marketa Skala, Andrew Wirth, Greg Wheeler, Adeline Lim, Mark Shaw, Penelope Schofield, Louis Irving, Benjamin Solomon
BACKGROUND: Stereotactic ablative body radiotherapy (SABR) is widely used to treat inoperable stage 1 non-small-cell lung cancer (NSCLC), despite the absence of prospective evidence that this type of treatment improves local control or prolongs overall survival compared with standard radiotherapy. We aimed to compare the two treatment techniques. METHODS: We did this multicentre, phase 3, randomised, controlled trial in 11 hospitals in Australia and three hospitals in New Zealand...
February 12, 2019: Lancet Oncology
https://read.qxmd.com/read/30770203/the-accuracy-evaluation-of-four-blood-glucose-monitoring-systems-according-to-iso-15197-2003-and-iso-15197-2013-criteria
#20
Huizhen Chen, Qingtao Yao, Yang Dong, Zhimei Tang, Ruiying Li, Baochao Cai, Ruili Wang, Qiu Chen
Self-monitoring of blood glucose is recommended to monitor glycaemic levels for the prevention and treatment of diabetes mellitus.The accuracy of blood glucose monitoring systems (BGMS) directly affects the health of the patients. In this study, we evaluated the accuracy of four different blood glucose monitoring systems, including Gold-Accu Meter, Nova StatStrip Xpress® Glucose Hospital Meter, Freestyle Optium Neo H® and Accu-Chek Performa according to ISO15197:2003 and ISO15197:2013 criteria. We found that four brands of BGMS (eight BGMS) all met the minimum requirements for system accuracy performance of ISO 15197:2003 and the accuracy criteria of ISO 15197:2013...
February 12, 2019: Primary Care Diabetes
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