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Concurrent surgery

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https://read.qxmd.com/read/30763215/role-of-noncoding-rnas-in-the-pathogenesis-of-abdominal-aortic-aneurysm
#1
Sandeep Kumar, Reinier A Boon, Lars Maegdefessel, Stefanie Dimmeler, Hanjoong Jo
Abdominal aortic aneurysm (AAA) is a local dilatation of the abdominal aortic vessel wall and is among the most challenging cardiovascular diseases as without urgent surgical intervention, ruptured AAA has a mortality rate of >80%. Most patients present acutely after aneurysm rupture or dissection from a previously asymptomatic condition and are managed by either surgery or endovascular repair. Patients usually are old and have other concurrent diseases and conditions, such as diabetes mellitus, obesity, and hypercholesterolemia making surgical intervention more difficult...
February 15, 2019: Circulation Research
https://read.qxmd.com/read/30759311/aquablation-of-the-prostate-for-the-treatment-of-lower-urinary-tract-symptoms-in-men-with-benign-prostatic-hyperplasia
#2
REVIEW
Eu Chang Hwang, Jae Hung Jung, Michael Borofsky, Myung Ha Kim, Philipp Dahm
BACKGROUND: New, minimally invasive surgeries have emerged as alternatives to transurethral resection of the prostate (TURP) for the management of lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH). Aquablation is a novel, minimally invasive, water-based therapy, combining image guidance and robotics for the removal of prostatic tissue. OBJECTIVES: To assess the effects of Aquablation for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia...
February 13, 2019: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/30756328/immediate-reconstruction-swing-room-scheduling-reduces-wait-times-to-surgery-and-increases-breast-reconstruction-rates
#3
Elaine McKevitt, Urve Kuusk, Carol Dingee, Rebecca Warburton, Jin-Si Pao, Nancy Y Van Laeken, Esta S Bovill
BACKGROUND: Despite benefits in quality of life, patient satisfaction, overall healthcare costs, and number of surgeries, historically fewer than 30% of patients undergo immediate breast reconstruction following mastectomy for breast cancer. A paucity of qualified oncologic and plastic surgeons coupled with inefficient use of operating room (OR) resources presents challenges in offering immediate breast reconstruction in a timely manner. To address these challenges, an immediate reconstruction swing room (IRSW) program was developed...
February 12, 2019: Annals of Surgical Oncology
https://read.qxmd.com/read/30755840/rethinking-the-doses-of-tissue-plasminogen-activator-and-deoxyribonuclease-administrated-concurrently-for-intrapleural-therapy-for-complicated-pleural-effusion-and-empyema
#4
Ayoub Innabi, Alok Surana, Bashar Alzghoul, Nikhil Meena
Background Complicated parapneumonic effusions empyema (CPEE) is fairly common and associated with increased morbidity and mortality. The Multicenter Intrapleural Sepsis Trial 2 (MIST 2) established the combination of intrapleural deoxyribonuclease (DNase) and tissue plasminogen activator (tPA) as an effective treatment for CPEE, thereby avoiding surgery and decreasing the length of hospitalization. MIST 2, however, used a labor-intensive protocol with some risk of bleeding. We hypothesize the simpler regimen of concurrent administration of intrapleural tPA and DNase (lower dose of tPA and a higher DNAse dose) to be equally effective with a decreased risk of bleeding...
February 21, 2018: Curēus
https://read.qxmd.com/read/30746710/factors-of-success-of-low-dose-macrolides-in-chronic-sinusitis-systematic-review-and-meta-analysis
#5
REVIEW
Kachorn Seresirikachorn, Nichana Suwanparin, Chanyanuch Srisunthornphanich, Wirach Chitsuthipakorn, Dichapong Kanjanawasee, Kornkiat Snidvongs
OBJECTIVE: To assess the prognostic factors that predict favorable outcomes of low-dose macrolides (LDMs) in treating chronic rhinosinusitis (CRS). METHODS: Randomized controlled trials studying the effects of LDMs in treating CRS were included. Data were pooled for meta-analysis. Primary outcome was Sino-Nasal Outcome Test (SNOT). Six prognostic factors: CRS subtypes, serum immunoglobulin (Ig)E level, membered lactone ring of macrolides, concurrent endoscopic sinus surgery (ESS), and dosage and duration of the LDMs were assessed by subgroup analyses...
February 11, 2019: Laryngoscope
https://read.qxmd.com/read/30745640/systemic-retinoids-and-scar-dehiscence
#6
Hasan Mete Aksoy, Berna Aksoy, Emel Çalikoglu
Systemic retinoids such as isotretinoin and acitretin are associated with numerous side effects but are therapeutically valuable in dermatological practice. Several studies have reported the wound-healing effects of treatment with concurrent systemic retinoids in addition to surgical treatments. Herein, we describe two patients with scar dehiscence that developed after initiation of systemic retinoid treatment following cutaneous surgery. In Case 1, isotretinoin was thought to decrease collagen production to a greater degree than did degradation during the wound remodeling phase, which resulted in wound dehiscence...
January 2019: Indian Journal of Dermatology
https://read.qxmd.com/read/30741358/treatment-approaches-for-cisplatin-ineligible-patients-with-invasive-bladder-cancer
#7
REVIEW
David J Einstein, Guru Sonpavde
Cisplatin has been established as an important agent in the neoadjuvant setting prior to radical cystectomy (RC) surgery for muscle-invasive urothelial cancer (MIUC) as well as in the unresectable or metastatic urothelial carcinoma (mUC) setting. Unfortunately, many patients in practice are felt to be "cisplatin-ineligible." Thus, it is vital that we develop treatment approaches and novel therapeutics for this population. We evaluate therapeutic alternatives to cisplatin-based treatment. For patients undergoing RC, there is no recommended alternative to neoadjuvant cisplatin-based combination therapy, and upfront RC or clinical trials are preferable...
February 11, 2019: Current Treatment Options in Oncology
https://read.qxmd.com/read/30741082/longitudinal-dyadic-associations-of-fear-of-cancer-recurrence-and-the-impact-of-treatment-in-prostate-cancer-patients-and-their-spouses
#8
Lisa M Wu, Heather McGinty, Ali Amidi, Katrin Bovbjerg, Michael A Diefenbach
BACKGROUND: Fear of cancer recurrence (FCR) in patients and their spouses is associated with reduced quality of life, but little is known about longitudinal dyadic associations of FCR between them. This study examined (i) the trajectory of FCR from pre-treatment to 12 months later; (ii) dyadic associations of FCR over time; and (iii) whether cancer treatment type predicted later FCR among prostate cancer patients and their spouses. METHODS: Sixty-nine patients and 71 spouses of patients with localized prostate cancer completed a FCR measure at baseline (pre-treatment), 6 months and 12 months later (post-treatment)...
February 11, 2019: Acta Oncologica
https://read.qxmd.com/read/30740579/perioperative-statin-use-and-acute-kidney-injury-in-patients-undergoing-partial-nephrectomy
#9
Shreyas S Joshi, Karen Ruth, Marc C Smaldone, David Y T Chen, Richard E Greenberg, Rosalia Viterbo, Alexander Kutikov, Robert G Uzzo
Background: Statin use is widespread among the general population. Data suggest a potentially beneficial effect of statin therapy on renal function following surgery. The impact of statins on post-partial nephrectomy (PN) renal function is unknown. We hypothesized that perioperative statin use may be associated with reduced rates of acute kidney injury (AKI) in patients undergoing PN. Objectives: To evaluate the effect of perioperative statin use on AKI rates in patients undergoing PN...
March 30, 2018: Kidney cancer
https://read.qxmd.com/read/30724766/photodynamic-therapy-in-head-and-neck-cancer-indications-outcomes-and-future-prospects
#10
Jeroen Meulemans, Pierre Delaere, Vincent Vander Poorten
PURPOSE OF REVIEW: To identify and review the recent literature on clinical applications, outcome, and new developments in photodynamic therapy (PDT) for the treatment of head and neck cancer. RECENT FINDINGS: Although PDT and surgery have a similar local control and recurrence rate, the gold standard of treatment for early-stage oral cavity cancer remains local surgery with, on indication, concurrent treatment of the neck. PDT proves its value in treatment of patients with field cancerization and patients with superficial recurrence after previous surgery and/or radiation, in whom surgical salvage would entail important morbidity...
February 4, 2019: Current Opinion in Otolaryngology & Head and Neck Surgery
https://read.qxmd.com/read/30719542/anterior-cruciate-ligament-reconstruction-with-concomitant-meniscal-surgery-a-systematic-review-and-meta-analysis-of-outcomes
#11
Mohamed Sarraj, Ryan P Coughlin, Max Solow, Seper Ekhtiari, Nicole Simunovic, Aaron J Krych, Peter MacDonald, Olufemi Ayeni
PURPOSE: The aim of this review was to compare the clinical outcomes of anterior cruciate ligament reconstruction (ACLR) with either meniscal repair or meniscectomy for concomitant meniscal injury. The primary hypothesis was that short-term clinical outcomes (≤ 2-year follow-up) for ACLR concomitant with either meniscal repair or resection would be similar. The secondary hypothesis was that ACLR with meniscal repair would result in better longer term outcomes compared with meniscal resection...
February 4, 2019: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://read.qxmd.com/read/30719172/the-survival-benefit-of-intensified-full-dose-xelox-chemotherapy-concomitant-to-radiotherapy-and-then-resting-period-consolidation-chemotherapy-in-locally-advanced-rectal-cancer
#12
Rong Zheng, ShiFeng Lian, XiaoXue Huang, GuoXian Guan, XiaoBo Li, Pan Chi, BenHua Xu
Purpose: To evaluate the effect of an intensified capecitabine and oxaliplatin (XELOX) chemoradiation treatment followed by one cycle of consolidation chemotherapy before surgery in locally advanced rectal cancer (LARC). Methods and Materials: Patients with histologically confirmed, newly diagnosed, locally advanced rectal adenocarcinoma (cT3-T4 and/or cN+) were enrolled. All patients received 3-dimensional conformal radiotherapy (3D-CRT) or intensity-modulated radiotherapy (IMRT) with a dose 50.4Gy in 25 fraction, with two cycles of concurrent XELOX chemotherapy...
2019: Journal of Cancer
https://read.qxmd.com/read/30718129/population-based-trend-analysis-of-voiding-cystourethrogram-ordering-practices-in-a-single-payer-healthcare-system-before-and-after-the-release-of-evaluation-guidelines
#13
J M Ming, L C Lee, M E Chua, J Zhu, L H Braga, M A Koyle, A J Lorenzo
INTRODUCTION: While voiding cystourethrogram (VCUG) is a widely-accepted test, it is invasive and associated with radiation exposure. Most cases of primary vesicoureteral reflux (VUR) are low-grade and unlikely to be associated with acquired renal scarring. To select patients at greatest risk, in 2011 the American Academy of Pediatrics (AAP) published guidelines for evaluation of children ages 2 - 24 months with urinary tract infections (UTIs). Similarly, in 2010 the Society for Fetal Urology (SFU) published guidelines for patients with hydronephrosis...
January 3, 2019: Journal of Pediatric Urology
https://read.qxmd.com/read/30718108/incidentally-discovered-intestinal-nonrotation-at-time-of-bariatric-surgery-which-operation-to-perform
#14
Gary Ko, Andrew Smith, Scott Cassie, Boris Zevin
BACKGROUND: An incidental finding of intestinal nonrotation at the time of bariatric surgery poses the following 2 dilemmas: (1) which operation to perform, and (2) whether an appendectomy should be performed concurrently. OBJECTIVES: To review the experience of 2 Bariatric Centers of Excellence with laparoscopic sleeve gastrectomy (LSG) in patients with intestinal nonrotation, and to perform a systematic review of the literature on this topic. SETTING: Two Bariatric Centers of Excellence as designated by the Ontario Bariatric Network...
January 11, 2019: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://read.qxmd.com/read/30717071/clinical-factors-influencing-the-development-of-extracranial-intracranial-bypass-graft-for-steno-occlusive-cerebrovascular-disease
#15
Shunsuke Nomura, Koji Yamaguchi, Tatsuya Ishikawa, Akitsugu Kawashima, Yoshikazu Okada, Takakazu Kawamata
OBJECTIVEEffectively retaining the patency of the extracranial-intracranial (ECIC) bypass is one of the most important factors in improving long-term results; however, the factors influencing bypass patency have not been discussed much. Therefore, the authors investigated factors influencing the development of the bypass graft.METHODSIn this retrospective study, the authors evaluated 49 consecutive hemispheres in 47 adult Japanese patients who had undergone ECIC bypass for chronic steno-occlusive cerebrovascular disease...
February 1, 2019: Neurosurgical Focus
https://read.qxmd.com/read/30716805/-application-of-modified-cricothyrotomy-in-the-multiplane-surgery-for-severe-obstructive-sleep-apnea-hypopnea-syndrome
#16
X Zhang, Y H Liu, J Wu, C B Gao, Y Zhao, Y Wang, D Wang
Objective: To explore the clinical value of modified cricothyrotomy in the multiplane surgery under general anesthesia for patients with severe obstructive sleep apnea hypopnea syndrome(OSAHS). Method: A retrospective review was made among 20 cases with severe OSAHS treated a concurrent multiplane surgery under the condition of modified cricothyrotomy with general anesthesia, performed during recent 3 years, with their clinical data reviewed carefully. General anesthesia was carried out by inserting trachea cannula through mouth at first, and then, modified cricothyrotomy was performed via a transverse incision, followed by pulling out trachea cannula and inserting endotracheal tube through thyrocricoid incision...
November 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://read.qxmd.com/read/30716194/lipemic-uveitis-and-its-etiologies-in-dogs-75-cases
#17
Nathaniel P Violette, Eric C Ledbetter
OBJECTIVE: To describe clinical features of dogs with lipemic uveitis (LU). ANIMALS STUDIED: Seventy-five dogs (114 eyes) with LU. PROCEDURES: Medical records of dogs examined by the Cornell University ophthalmology service with a clinical diagnosis of LU between 2008 and 2017 were analyzed. Signalment and clinical case aspects, including concurrent ocular disease, systemic disease, and previous ophthalmic surgery, were recorded. RESULTS: Lipemic uveitis was diagnosed in 114 eyes of 75 dogs...
February 4, 2019: Veterinary Ophthalmology
https://read.qxmd.com/read/30715169/genetics-of-breast-implant-associated-anaplastic-large-cell-lymphoma-bia-alcl
#18
Naoki Oishi, Roberto N Miranda, Andrew L Feldman
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), a newly included provisional entity in the 2016 revision of the World Health Organization classification, is a distinct form of CD30-positive T-cell non-Hodgkin lymphoma that arises in association with a breast implant after reconstructive or cosmetic surgery. In addition to its characteristic clinical presentation, recent studies using next-generation sequencing have revealed that BIA-ALCL has a unique pattern of genetic alterations. BIA-ALCL is consistently negative for ALCL-related gene rearrangements involving ALK, DUSP22, and TP63...
January 31, 2019: Aesthetic Surgery Journal
https://read.qxmd.com/read/30712019/magnetic-resonance-imaging-after-external-beam-radiotherapy-and-concurrent-chemotherapy-for-locally-advanced-cervical-cancer-helps-to-identify-patients-at-risk-of-recurrence
#19
Martina Aida Angeles, Pauline Baissas, Eric Leblanc, Amélie Lusque, Gwénaël Ferron, Anne Ducassou, Carlos Martínez-Gómez, Denis Querleu, Alejandra Martinez
OBJECTIVE: Tumor volume and regression after external beam radiotherapy have been shown to be accurate parameters to assess treatment response via magnetic resonance imaging (MRI). The aim of the study was to evaluate the prognostic value of tumor size reduction rate after external beam radiotherapy and chemotherapy prior to brachytherapy. METHODS: Patients with locally advanced cervical cancer treated at two French comprehensive cancer centers between 1998 and 2010 were included...
February 1, 2019: International Journal of Gynecological Cancer
https://read.qxmd.com/read/30709599/effects-of-congenital-heart-disease-treatmenton-quality-of-life
#20
Myrto Boukovala, Jan Müller, Peter Ewert, Alfred Hager
With rising survival rates of patients with congenital heart disease (CHD), functional health variables have become the key aspect in treatment evaluation. The effectiveness of various treatment options on the health-related quality of life (HRQoL) and the objectively measured exercise capacity as peak oxygen uptake (VO2 peak) remains rather unclear and hence, its investigation is the primary aim of this study. Data from 1014 patients (≥14-years-old, various CHD) were retrospectively reviewed. The patients had completed at least twice the SF-36 questionnaire on HRQoL prior to a cardiopulmonary exercise test...
January 8, 2019: American Journal of Cardiology
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