Shi Qiu, Yaqi Qiu, Linghui Deng, Ling Nie, Liming Ge, Xiaonan Zheng, Di Jin, Kun Jin, Xianghong Zhou, Xingyang Su, Boyu Cai, Jiakun Li, Xiang Tu, Lina Gong, Liangren Liu, Zhenhua Liu, Yige Bao, Jianzhong Ai, Tianhai Lin, Lu Yang, Qiang Wei
BACKGROUND: Bladder cancer, characterized by a high potential of tumor recurrence, has high lifelong monitoring and treatment costs. To date, tumor cells with intrinsic softness have been identified to function as cancer stem cells in several cancer types. Nonetheless, the existence of soft tumor cells in bladder tumors remains elusive. Thus, our study aimed to develop a micro-barrier microfluidic chip to efficiently isolate deformable tumor cells from distinct types of bladder cancer cells...
June 30, 2023: Chinese Medical Journal