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Silvio Collani, Manuela Neumann, Levi Yant, Markus Schmid
The transition to flowering is a crucial step in the plant life cycle that is controlled by multiple endogenous and environmental cues, including hormones, sugars, temperature, and photoperiod. Permissive photoperiod induces the expression of FLOWERING LOCUS T (FT) in the phloem companion cells (PCC) of leaves. The FT protein then acts as a florigen that is transported to the shoot apical meristem (SAM), where it physically interacts with the bZIP transcription factor FD and 14-3-3 proteins. However, despite the importance of FD in promoting flowering, its direct transcriptional targets are largely unknown...
February 15, 2019: Plant Physiology
Zanping Han, Bin Wang, Lei Tian, Shunxi Wang, Jun Zhang, ShuLei Guo, Hengchao Zhang, Lengrui Xu, Yanhui Chen
Seed germination, as an integral stage of crop production, directly affects Zea mays (maize) yield and grain quality. However, the molecular mechanisms of seed germination remain unclear in maize. We performed comparative transcriptome analysis of two maize inbred lines, Yu82 and Yu537A, at two stages of seed germination. Expression profile analysis during seed germination revealed that a total of 3381 and 4560 differentially expressed genes (DEGs) were identified in Yu82 and Yu537A at the two stages. Transcription factors were detected from several families, such as the bZIP, ERF, WRKY, MYB, and bHLH families, which indicated that these transcription factor families might be involved in driving seed germination in maize...
February 14, 2019: Physiologia Plantarum
Arpita Das, Krishnendu Pramanik, Rishu Sharma, Saikat Gantait, Joydeep Banerjee
Germin-like proteins (GLPs) are involved in biotic and abiotic stress tolerance in different plant species. Rice (Oryza sativa L.) genome contains about 40 GLP family member proteins in nine chromosomes. Although some of the rice GLP (OsGLP) promoters have been studied through in silico analysis as well as experimentally, studies regarding the distribution pattern of the biotic and abiotic stress associated transcription factor binding sites (TFbs) in the promoter regions of OsGLP genes have not been attempted thoroughly...
2019: PloS One
Veroni S Sri Theivakadadcham, Benjamin G Bergey, Emanuel Rosonina
Sequence-specific transcription factors (TFs) represent one of the largest groups of proteins that is targeted for SUMO post-translational modification, in both yeast and humans. SUMO modification can have diverse effects, but recent studies showed that sumoylation reduces the interaction of multiple TFs with DNA in living cells. Whether this relates to a general role for sumoylation in TF binding site selection, however, has not been fully explored because few genome-wide studies aimed at studying such a role have been reported...
February 14, 2019: PLoS Genetics
Arpita Yadav, Souvika Bakshi, Premachandran Yadukrishnan, Maneesh Lingwan, Ulla Dolde, Stephan Wenkel, Shyam K Masakapalli, Sourav Datta
The bZIP transcription factor ELONGATED HYPOCOTYL 5 (HY5) represents a major hub in the light-signaling cascade both under visible and UV-B light. The mode of transcriptional regulation of HY5, especially under UV-B light, is not well characterized. B-BOX (BBX) transcription factors regulate HY5 transcription and also post-transcriptionally modulate HY5 to control photomorphogenesis under white light. Here, we identify BBX31 as a key signaling intermediate in visible and UV-B light signal transduction in Arabidopsis thaliana...
February 5, 2019: Plant Physiology
Joungsu Joo, Youn Hab Lee, Sang Ik Song
OsbZIP42 is a positive regulator of ABA signaling and drought stress tolerance. The activation of OsbZIP42 depends on stress-/ABA-activated protein kinase 4 (SAPK4) and an additional ABA-dependent modification of OsbZIP42. Basic leucine zipper transcription factors (bZIP TFs) play important roles in the ABA signaling pathway in plants. Rice OsbZIP42 is a member of the group E bZIP, which is an ortholog of Arabidopsis group A bZIP. This latter group includes abscisic acid-responsive element (ABRE)-binding factors (ABFs) involved in abiotic stress tolerance...
February 2, 2019: Planta
Jinyi Liu, Jinjin Chu, Chuangju Ma, Yueting Jiang, Yuanchun Ma, Jinsong Xiong, Zong-Ming Cheng
Overexpression of grapevine VvABF2 gene could enhance osmotic stress tolerance in Arabidopsis thaliana but fully required for ABA signaling. The abscisic acid (ABA)-dependent AREB/ABF-SnRK2 pathway has been demonstrated to play a pivotal role in response to osmotic stress in model plants. However, its function in other specific species, for example grapevine, has not been fully characterized. In this study, grapevine (Vitis vinifera L.) ABSCISIC ACID RESPONSE ELEMENT-BINDING FACTOR2 (VvABF2), a homologous gene of AREB/ABFs form Arabidopsis, was isolated and constitutively expressed in Arabidopsis under the control of the cauliflower mosaic virus 35S promoter...
February 2, 2019: Plant Cell Reports
Xiumei Luo, Chengjian Xie, Jinyan Dong, Xingyong Yang
Verticillium dahliae is a soil-borne, hemibiotrophic phytopathogenic fungus that causes Verticillium wilt in a broad range of economic crops. The microsclerotia (MS), which act as the main host inoculum, can survive long-term in soil resulting in uncontrollable disease. In order to clarify the mechanism of MS formation, we sequenced the whole genome-wide expression profile of V. dahliae strain V991. Compared with M1 (no MS formation), during the process of MS formation and maturation, 1354, 1571, and 1521 unique tags were significantly regulated in M2, M3, and M4 library, respectively...
January 30, 2019: Fungal Genetics and Biology: FG & B
Yuyan Sun, Min Fan, Yanjun He
Cucumber green mottle mosaic virus (CGMMV) is a member of the genus Tobamovirus , which cause diseases in cucurbits, especially watermelon. In watermelon, symptoms develop on the whole plant, including leaves, stems, peduncles, and fruit. To better understand the molecular mechanisms of watermelon early responses to CGMMV infection, a comparative transcriptome analysis of 24 h CGMMV-infected and mock-inoculated watermelon leaves was performed. A total of 1641 differently expressed genes (DEGs) were identified, with 886 DEGs upregulated and 755 DEGs downregulated after CGMMV infection...
January 31, 2019: International Journal of Molecular Sciences
Shimrit Avraham, Ben Korin, Sharon Aviram, Dvir Shechter, Yuval Shaked, Ami Aronheim
The activating transcription factor 3 (ATF3) and the c-Jun dimerization protein 2 (JDP2) are members of the basic leucine zipper (bZIP) family of transcription factors. These proteins share a high degree of homology and both can activate or repress transcription. Deficiency of either one of them in the non-cancer host cells was shown to reduce metastases. As ATF3 and JDP2 compensate each other's function, we studied the double deficiency of ATF3 and JDP2 in the stromal tumor microenvironment. Here, we show that mice with ATF3 and JDP2 double deficiency (designated thereafter dKO) developed larger tumors with high vascular perfusion and increased cell proliferation rate compared to wild type (WT) mice...
January 22, 2019: Oncogene
James Saliba, Baptiste Coutaud, Vera Solovieva, Fangshi Lu, Volker Blank
Cytokines play key roles in a variety of reproductive processes including normal parturition as well as preterm birth. Our previous data have shown that MAFF, a member of the MAF family of bZIP transcription factors, is rapidly induced by pro-inflammatory cytokines in PHM1-31 myometrial cells. We performed loss-of-function studies in PHM1-31 cells to identify MAFF dependent genes. We showed that knockdown of MAFF significantly decreased CXCL1 chemokine and CSF3 cytokine transcript and protein levels. Using chromatin immunoprecipitation analyzes, we confirmed CXCL1 and CSF3 genes as direct MAFF targets...
January 22, 2019: Journal of Cellular and Molecular Medicine
Keshalini Sabaratnam, Max Renner, Guido Paesen, Karl Harlos, Venugopal Nair, Raymond J Owens, Jonathan M Grimes
cAMP response element binding protein 3 (CREB3) is an endoplasmic reticulum (ER) membrane-bound transcription factor, which belongs to the basic leucine zipper (bZIP) superfamily of eukaryotic transcription factors. CREB3 plays a role in the ER-stress induced unfolded protein response (UPR) and is a multifunctional cellular factor implicated in a number of biological processes including cell proliferation and migration, tumour suppression, and immune-related gene expression. To gain structural insights into the transcription factor, we determined the crystal structure of the conserved bZIP domain of chicken CREB3 (chCREB3) to a resolution of 3...
January 17, 2019: Protein Science: a Publication of the Protein Society
Zhihui Wang, Liying Yan, Liyun Wan, Dongxin Huai, Yanping Kang, Lei Shi, Huifang Jiang, Yong Lei, Boshou Liao
BACKGROUND: Plant basic leucine zipper (bZIP) transcription factors play crucial roles in plant growth, development, and abiotic stress responses. However, systematic investigation and analyses of the bZIP gene family in peanut are lacking in spite of the availability of the peanut genome sequence. RESULTS: In this study, we identified 50 and 45 bZIP genes from Arachis duranensis and A. ipaensis genomes, respectively. Phylogenetic analysis showed that Arachis bZIP genes were classified into nine groups, and these clusters were supported by several group-specific features, including exon/intron structure, intron phases, MEME motifs, and predicted binding site structure...
January 16, 2019: BMC Genomics
Tengfei Liu, Tingting Zhou, Meiting Lian, Tiantian Liu, Juan Hou, Raina Ijaz, Botao Song
Abscisic acid (ABA) plays crucial roles in plant development and adaption to environmental stresses. The ABA-responsive element binding protein/ABRE-binding factor and ABA INSENSITIVE 5 (AREB/ABF/ABI5) gene subfamily members, which belong to the basic domain/leucine zipper (bZIP) transcription factors family, participate in the ABA-mediated signaling pathway by regulating the expression of their target genes. However, information about potato ( Solanum tuberosum ) AREB/ABF/ABI5 subfamily members remains scarce...
January 14, 2019: International Journal of Molecular Sciences
Yunpeng Gai, Bing Liu, Haijie Ma, Lei Li, Xinglong Chen, Susan Moenga, Brendan Riely, Amna Fayyaz, Mingshuang Wang, Hongye Li
The tangerine pathotype of A. alternata, which produces a unique host-selective ACT toxin causes brown spots on citrus leaves and fruits. In this study, we report a methionine biosynthesis regulator (MetR), which belong to bZIP transcription factor, is required for methionine metabolism, oxidative stress tolerance and pathogenicity. We generated two ΔAaMetR mutants in the tangerine pathotype of Alternaria alternata and investigated the resulting mutant phenotypes. The ΔAaMetR disruption mutant grew poorly in the absence of methionine and unable to produce conidia...
February 2019: Microbiological Research
Shengyang Wu, Pinghui Zhu, Bowei Jia, Junkai Yang, Yang Shen, Xiaoxi Cai, Xiaoli Sun, Yanming Zhu, Mingzhe Sun
Following publication of the original article [1], the author reported that their given name was misspelled.
January 14, 2019: BMC Plant Biology
Tao Luo, Mengzhu Xian, Chen Zhang, Chunni Zhang, Liyong Hu, Zhenghua Xu
Slow germination speed caused by low temperature stress intensifies the risk posed by adverse environmental factors, contributing to low germination rate and reduced production of rapeseed. The purpose of this study was to understand the transcriptional regulation mechanism for rapid germination of rapeseed. The results showed that seed components and size do not determine the seed germination speed. Different temporal transcriptomic profiles were generated under normal and low temperature conditions in genotypes with fast and slow germination speeds...
January 11, 2019: Scientific Reports
Muhammad Asad Ullah Asad, Shamsu Ado Zakari, Qian Zhao, Lujian Zhou, Yu Ye, Fangmin Cheng
Abiotic stresses trigger premature leaf senescence by affecting some endogenous factors, which is an important limitation for plant growth and grain yield. Among these endogenous factors that regulate leaf senescence, abscisic acid (ABA) works as a link between the oxidase damage of cellular structure and signal molecules responding to abiotic stress during leaf senescence. Considering the importance of ABA, we collect the latest findings related to ABA biosynthesis, ABA signaling, and its inhibitory effect on chloroplast structure destruction, chlorophyll (Chl) degradation, and photosynthesis reduction...
January 10, 2019: International Journal of Molecular Sciences
Yu Ying Liu, Bin Li, Hui Guo
Non-small-cell carcinoma (NSCLC) is the most common cancer along with high mortality rate worldwide. In the present study, our data showed that lncRNA MAF BZIP Transcription Factor G Antisense RNA 1 (MAFG-AS1) was over-expressed in NSCLC tissues and cell lines. Overexpression of MAFG-AS1 promoted the migration, invasion and enhanced epithelial-mesenchymal transition (EMT) of NSCLC cell. In addition, miR-339-5p was predicted to be a target of MAFG-AS1 and the level of miR-339-5p was down-regulated in NSCLC. Over-expression of MAFG-AS1 significantly decreased the level of miR-339-5p in NSCLC cell...
January 1, 2019: Cell Biology International
Zhengkun Qiu, Haijing Wang, Dongjing Li, Bingwei Yu, Qiuling Hui, Shuangshuang Yan, Zejun Huang, Xia Cui, Bihao Cao
High quantities of anthocyanins in plants confer potential protective benefits to biotic and abiotic stressors. Studies have shown that the bZIP transcription factor HY5 plays a key role in controlling anthocyanin accumulation in response to light. However, in hy5 mutants, residual anthocyanins have been detected, indicating that other regulators exist to regulate anthocyanin biosynthesis in an HY5-independent manner. Here, we employed the CRISPR/Cas9 system to specifically induce targeted mutagenesis of SlHY5 in the purple tomato cultivar 'Indigo Rose...
December 31, 2018: Plant & Cell Physiology
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