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Hantavirus in childrens

Fabian Echterdiek, Daniel Kitterer, M Dominik Alscher, Vedat Schwenger, Bettina Ruckenbrod, Martin Bald, Joerg Latus
BACKGROUND: Hantavirus infections are endemic worldwide, and its incidence in Europe has been steadily increasing. In Western Europe, hantavirus infections are typically caused by Puumala hantavirus and cause nephropathia epidemica (NE), a mild form of haemorrhagic fever with renal syndrome. Up to now, there is only little data about the course of acute NE in children, but it has been suggested that hantavirus infections take a lighter course in children when compared to adults. We performed a retrospective analysis of adults and children diagnosed with acute NE in two counties in South-Western Germany to investigate if there are differences in the course of the disease...
March 14, 2019: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Lidsy Ximenes Fonseca, Stefan Vilges de Oliveira, Elisabeth Carmen Duarte
OBJECTIVE: to describe the magnitude and temporal and spatial distribution of hantavirus cases and deaths in Brazil between 2007 and 2015. METHODS: descriptive study with data from the Notifiable Diseases Information System (SINAN). RESULTS: 1,060 cases and 410 deaths were reported in the period; hantavirus lethality was 39.0%, varying according to month (from 28.6% in November to 50.7% in December), sex (37.4% in males and 42.6% in females), age (higher lethality in the elderly and children) and Brazilian regions (46...
June 28, 2018: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
Tamara K Dzagurova, Evgeniy A Tkachenko, Aydar A Ishmukhametov, Mariya V Balovneva, Boris Klempa, Detlev H Kruger
BACKGROUND: Very recently, a novel European hantavirus, Sochi virus, has been discovered which causes severe courses of hantavirus disease with a case fatality rate of about 15 percent. OBJECTIVES: We aimed to study to which extent and with which clinical severity children were affected by Sochi virus infection. STUDY DESIGN: Sochi virus infection of patients was confirmed by molecular, serological, and epizoonotic studies. Clinical and laboratory parameters were analyzed for the age group of up to 15 years (n = 6) in comparison to all older patients (n = 56)...
April 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
Someshwar Chate, Ira Shah, Hiren Doshi
Hantaviruses are a group of antigenically distinct viruses carried out in rodents and insectivores. Humans are accidental hosts and get infected by aerosols generated from contaminated urine, faeces and saliva of infected rodents. Hantaviruses are identified as aetiological agents of two human diseases, haemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. Hantavirus causing pulmonary renal disease has rarely been reported in children in India. Hantavirus infection is uncommon under the age of 12 years...
July 2017: Indian Journal of Medical Microbiology
Francisca Valdivieso, Claudia Gonzalez, Manuel Najera, Andrea Olea, Analia Cuiza, Ximena Aguilera, Gregory Mertz
Andes hantavirus cardiopulmonary syndrome, transmitted by Oligoryzomys longicaudatus, has no approved treatment, a case fatality rate of 35%, and documented person-to-person transmission. An Andes vaccine, highly needed for prevention, is in development. We aimed to evaluate knowledge, attitudes and practices (KAP) regarding hantavirus disease and willingness to participate in a future Andes vaccine trials through a cross sectional face-to-face oral survey of a randomly selected adult sample from 2 rural communes in southern Chile...
April 3, 2017: Human Vaccines & Immunotherapeutics
Mehdi Mirsaeidi, Hooman Motahari, Mojdeh Taghizadeh Khamesi, Arash Sharifi, Michael Campos, Dean E Schraufnagel
The rate of global warming has accelerated over the past 50 years. Increasing surface temperature is melting glaciers and raising the sea level. More flooding, droughts, hurricanes, and heat waves are being reported. Accelerated changes in climate are already affecting human health, in part by altering the epidemiology of climate-sensitive pathogens. In particular, climate change may alter the incidence and severity of respiratory infections by affecting vectors and host immune responses. Certain respiratory infections, such as avian influenza and coccidioidomycosis, are occurring in locations previously unaffected, apparently because of global warming...
August 2016: Annals of the American Thoracic Society
V V Leont'ev
In the article there are considered the environmental and biological prerequisites for the dynamics of hemorrnagic fever with renal syndrome (HFRS) morbidity rate in the population of the city of Naberezhnye Chelny and the municipal districts located in the north-eastern part of the Republic of Tatarstan, a subdivision of Russian Federation. The territory of the Republic of Tatarstan is included into the body of Volga Federal District of the Russian Federation and is located within the boundaries in coniferous taiga and temperate forests, forest-steppe and steppe geographical areas...
May 2015: Gigiena i Sanitariia
Alok Kumar, Kandamaran Krishnamurthy, Anders L Nielsen
Emerging picture of hantavirus infection in the South America is characterized by greater proportion of childhood infection and wider spectrum of disease from mild asymptomatic to lethal cardiopulmonary disease. Barbados is endemic for dengue and leptospirosis, both of which share clinical features with hantavirus infection and in many cases neither of these diagnosis could be confirmed. We investigate whether some of the children hospitalized with suspected dengue could indeed have been hantavirus infections...
January 2016: Journal of Infection and Public Health
Peter J Hotez, Laila Woc-Colburn, Maria Elena Bottazzi
A review of the literature since 2009 reveals a staggering health and economic burden resulting from neglected tropical diseases in Panama and the six countries of Central America (referred to collectively here as 'Central America'). Particularly at risk are the 10.2million people in the region who live on less than $2 per day, mostly in Guatemala, Honduras, Nicaragua and El Salvador. Indigenous populations are especially vulnerable to neglected tropical diseases. Currently, more than 8million Central American children require mass drug treatments annually (or more frequently) for their intestinal helminth infections, while vector-borne diseases are widespread...
August 2014: International Journal for Parasitology
Marcela Ferrés G, Carmen Sandoval C, Iris Delgado B, Viviana Sotomayor P, Andrea Olea N, Pablo A Vial C
BACKGROUND: The first cases of Hantavirus cardiopulmonary syndrome in children were described in the United States and represented 8% of the total reported cases; in Chile, the proportion of pediatric cases represents 15% of all national cases. AIM: To describe the epidemiology and clinical course of 82 children reported to the Chilean Ministry of Health up to 2007 and to characterize more extensively a subgroup of 24 children whose detailed clinical data were available...
February 2010: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
(no author information available yet)
Hantavirus pulmonary syndrome (HPS) is a reportable infectious disease with a high case-fatality rate, transmitted to humans by exposure to rodents. Each year, 20--40 cases of HPS occur in the United States; cases in persons aged <17 years make up fewer than 7% of those cases, and cases in children aged <10 years are exceptionally rare. CDC received reports of five pediatric cases of HPS occurring during May 16--November 25, 2009, among children aged 6--14 years from Arizona, California, Colorado, and Washington...
December 25, 2009: MMWR. Morbidity and Mortality Weekly Report
Jonathan F Guilfoyle, Andrew J Macnab
INTRODUCTION: A 14-year-old boy with cardiorespiratory failure was referred for air medical transport. The complexity of care during air medical transport and subsequent diagnosis of hantavirus warranted a post hoc review of the literature to establish optimal transport management criteria. METHODS: This is a case report and literature review, defining epidemiology, presentation, cause of pulmonary edema and cardiac failure, management, and outcome. RESULTS: Hantavirus cardiopulmonary syndrome is rare in children...
November 2008: Air Medical Journal
R Bogdanović, A Gligić, V Nikolić, M Ognjanović
During an outbreak of haemorrhagic fever with renal syndrome (HFRS) in 1989, five children (3 girls, 2 boys, aged 6.8-16 years) with severe clinical form of the disease, were treated at the Institute of Mother and Child Health of Serbia; four of them were followed-up 22-28 months thereafter. The main clinical features were: fever, headache, myalgia, abdominal and back pains, and vomiting in all, and haemorrhagic syndrome in three; renal syndrome with severe acute renal failure in all five patients. All the patients recovered...
January 1995: Srpski Arhiv za Celokupno Lekarstvo
Jirí Dusek, Milan Pejcoch, Alexander Kolsky, Tomas Seeman, Vladimir Nemec, Josef Stejskal, Karel Vondrak, Jan Janda
The first three children with Puumala virus nephropathy diagnosis in the Czech Republic are reported on. A boy and two girls were admitted with symptoms of interstitial nephritis. The medical history in all children revealed flu-like symptoms. All patients were mildly pyrexial and had elevated erythrocytes sedimentation rate, C-reactive protein and low hemoglobin levels. Serum creatinine levels were elevated and proteinuria exceeded 700 mg/L in all children. Tubular proteinuria, glycosuria, high urinary N-acetyl-beta-D-glucosaminidase levels and alpha-1-microglobulin levels confirmed the tubular lesion...
December 2006: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Gary D Overturf
No abstract text is available yet for this article.
April 2005: Pediatric Infectious Disease Journal
V Nikolić, R Bogdanović, M Ognjanović, N Stajić
UNLABELLED: Acute tubulointerstitial nephritis (ATIN) is a rare renal disorder in children. Patients usually present non-specific symptoms and signs so that the diagnosis of ATIN is often delayed. The disease may be infection- or drug-induced or it may occur without a known cause. Early recognition and appropriated therapy usually lead to an excellent prognosis. The aim of the study was to describe clinical and laboratory findings and the course of ATIN in 21 patients, that are typical enough to enable early recognition of the disease as it is potentially reversible...
May 2001: Srpski Arhiv za Celokupno Lekarstvo
J van der Werff ten Bosch, P Heyman, D Potters, S Peeters, C Cochez, D Piérard
Hantavirus infection due to Puumala virus causes nephropathica epidemica, a disorder characterized by fever, haematological abnormalities, mild renal dysfunction and ophthalmological abnormalities. The prevalence in most European countries is low, but the virus can be endemic. In children, hantavirus infection is rare. This paper describes a young girl diagnosed with hantavirus infection. The patient presented with high fever, proteinuria, haematuria and eye lesions, but other typical hallmarks of the disease, such as thrombocytopenia and renal dysfunction, were absent...
August 2004: Acta Paediatrica
Blas Armien, Juan Miguel Pascale, Vicente Bayard, Carlos Munoz, Itza Mosca, Gladis Guerrero, Anibal Armien, Evelia Quiroz, Zoila Castillo, Yamizel Zaldivar, Fernando Gracia, Brian Hjelle, Frederick Koster
The first outbreak of hantavirus pulmonary syndrome (HPS) in Central America was documented on the Azuero peninsula of Panama in late 1999 and 2000. Reverse transcriptase-polymerase chain reaction evidence implicated only Choclo virus in symptomatic HPS with a mortality rate of 20%, although two rodent-borne hantaviruses (Choclo virus and Calabazo virus) were identified in the peridomestic habitat. Neighborhood serosurveys around case households found seroprevalence rates as high as 30%, the highest in the Americas except for western Paraguay...
June 2004: American Journal of Tropical Medicine and Hygiene
Marcela Ferrés, Pablo Vial
PURPOSE OF REVIEW: This article focuses on recent developments in knowledge about hantavirus infections and hantavirus cardiopulmonary syndrome in children. We highlight clinical characterization, epidemiology, pathogenesis, diagnostic techniques, and current alternatives for treatment and prevention. RECENT FINDINGS: After the first description of hantavirus pulmonary syndrome (HPS) in 1993 in the United States, new cases of HPS and new hantavirus species have been described throughout the Americas...
February 2004: Current Opinion in Pediatrics
M M Ramos, G D Overturf, M R Crowley, R B Rosenberg, B Hjelle
OBJECTIVE: Sin Nombre hantavirus (SNV) is the leading causative agent of hantavirus cardiopulmonary syndrome (HCPS) in the United States and Canada. Relatively few cases of HCPS have involved children. This report describes the clinical characteristics of a series of pediatric cases of SNV infection in the United States and Canada from 1993 through March 2000. METHODS: We analyzed clinical and laboratory data on 13 patients who were </=16 years old with SNV infection from 1993 through March 2000 identified from a database at the University of New Mexico...
August 2001: Pediatrics
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