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Vital Sign Monitor

Guanglei Ye, Bina Guo
This paper demonstrates a BSN-based portable monitor integrating micro sensors with mobile devices for monitoring and diagnosing obstructive sleep apnea syndrome (OSAS) at home. The system uses a micro hot-film flow sensor to detect respiratory flow, uses tri-axis micro accelerometer to detect body posture and motion intensity, and uses a micro photoelectric sensor to detect oxygen saturation of blood. The real-time vital signs are detected and transmitted wirelessly to a mobile device. The transmitted data are processed and analyzed in the mobile device and can be further transmitted to a remote medical center and physicians through mobile cellular networks or Internet for comprehensively analyzing, assessing, and diagnosing to the diseases...
January 30, 2019: Zhongguo Yi Liao Qi Xie za Zhi, Chinese Journal of Medical Instrumentation
Francisco Javier Mendoza, Juan Manuel Serrano-Rodriguez, Alejandro Perez-Ecija
BACKGROUND: Nonsteroidal anti-inflammatory drugs are administered in horses for several systemic diseases. Selective cyclooxygenase-2 inhibitors are preferred because of lower risk of adverse effects. Several meloxicam formulations have been tested in horses, but a recently marketed granule oral formulation has not been studied. OBJECTIVE: To characterize the pharmacokinetics of a novel granule meloxicam formulation in fasted and fed horses, and to compare pharmacokinetic features with oral suspension and tablets...
February 15, 2019: Journal of Veterinary Internal Medicine
Joo Heung Yoon, Lidan Mu, Lujie Chen, Artur Dubrawski, Marilyn Hravnak, Michael R Pinsky, Gilles Clermont
Tachycardia is a strong though non-specific marker of cardiovascular stress that proceeds hemodynamic instability. We designed a predictive model of tachycardia using multi-granular intensive care unit (ICU) data by creating a risk score and dynamic trajectory. A subset of clinical and numerical signals were extracted from the Multiparameter Intelligent Monitoring in Intensive Care II database. A tachycardia episode was defined as heart rate ≥ 130/min lasting for ≥ 5 min, with ≥ 10% density. Regularized logistic regression (LR) and random forest (RF) classifiers were trained to create a risk score for upcoming tachycardia...
February 14, 2019: Journal of Clinical Monitoring and Computing
Isabelle Khalifa, Ran D Goldman
Question I recently saw in my office a patient whom I had initially diagnosed with anorexia nervosa 6 months earlier and she was continuing to lose weight. Her physical examination findings in the office revealed a blood pressure of 85/55 mm Hg and a heart rate of 55 beats/min at rest. Should patients such as this one be sent to the hospital for inpatient monitoring and treatment? Answer There is a lack of clear evidence-based guidelines for hospital admission of adolescents with anorexia nervosa, resulting in a high degree of variation in practices among physicians...
February 2019: Canadian Family Physician Médecin de Famille Canadien
Danielle Walsh, Robert Gekle, Robert Bramante, Eric Decena, Christopher Raio, David Levy
The sepsis order set at our institution was created with the intent to facilitate the prompt initiation of appropriate sepsis care. Once clinical features meeting criteria for systemic inflammatory response syndrome (SIRS) are identified and an infectious source is considered, a "sepsis huddle" is concomitantly initiated. The sepsis huddle was implemented in March of 2016 in order to increase compliance with the sepsis bundles. The sepsis huddle is called via overhead paging system in the emergency department (ED) to notify all staff that there is a patient present who meets SIRS criteria with concern for sepsis requiring immediate attention...
February 7, 2019: American Journal of Emergency Medicine
Lutz Frölich, Glen Wunderlich, Claus Thamer, Michael Roehrle, Miguel Garcia, Bruno Dubois
BACKGROUND: There are currently no approved treatments for the prodromal stage of Alzheimer's disease (AD). Approved symptomatic treatments for mild-to-moderate AD include acetylcholinesterase inhibitors and memantine, but more efficacious treatments are needed. BI 409306 is a potent and selective phosphodiesterase 9 inhibitor assessed for the symptomatic treatment of AD. Efficacy and safety of BI 409306 was analysed in two phase II proof-of-concept clinical trials in cognitive impairment associated with prodromal AD (study 1) and mild AD (study 2)...
February 12, 2019: Alzheimer's Research & Therapy
William A Teeter, Matthew J Bradley, Anna Romagnoli, Peter Hu, Yao Li, Deborah M Stein, Thomas M Scalea, Megan Brenner
The purpose of this study is to compare end-tidal carbon dioxide (EtCO₂) during resuscitation of open-chest cardiac massage (OCCM) with aortic cross-clamp (ACC) versus receiving resuscitative endovascular balloon occlusion of the aorta (REBOA) with closed-chest compressions (CCCs). Patients who received REBOA were compared with patients receiving OCCM for traumatic arrest using continuous vital sign monitoring and videography. Thirty-three patients were enrolled in the REBOA group and 18 patients were enrolled in the OCCM group...
October 1, 2018: American Surgeon
Paul D Schlosser, Tobias Grundgeiger, Penelope M Sanderson, Oliver Happel
PURPOSE: Supervising anesthesiologists overseeing several operating rooms must be aware of the status of multiple patients, so they can consult with the anesthetist in single operating rooms or respond quickly to critical events. However, maintaining good situation awareness can be challenging when away from patient bedsides or a central monitoring station. In this proof-of-concept study, we evaluated the potential of a head-worn display that showed multiple patients' vital signs and alarms to improve supervising anesthesiologists' situation awareness...
February 5, 2019: Journal of Clinical Monitoring and Computing
Lisa-Marie Muellerleile, Alexander Tichy, Barbara Nell
OBJECTIVE: To evaluate ocular and general safety of topical anti-human VEGF bevacizumab and the effect on serum vascular endothelial growth factor (VEGF) values in healthy dogs. PROCEDURES: Nine university-owned beagles received 0.05 mL of 0.25% bevacizumab eyedrops (Avastin® , Roche) in one eye and 0.05 mL of 0.9% saline solution in the other eye as a control, administered at 12 hours intervals over a period of 28 days. Continuous monitoring for vital parameters and ocular examinations were conducted...
February 4, 2019: Veterinary Ophthalmology
Mingyi Chen, Hosung Chun, Ivan Dario Castro Miller, Tom Torfs, Qiuyang Lin, Chris Van Hoof, Guoxing Wang, Yong Lian, Nick Van Helleputte
Electrocardiogram (ECG) is one of the major physiological vital signs and an effective monitoring method for patients with cardiovascular diseases. However, existing ECG recordings require a galvanic body contact, which is unpractical in daily life. This paper presents the design of an ECG chip that facilitates non-contact ECG recording through capacitive coupling. With the input impedance boosting techniques, as well as an active driven-right-leg (DRL) which boosts common-mode rejection ratio (CMRR) to 70 dB, the single-ended capacitive feedback active electrode (AE) achieves ultra-high input impedance of 400 GΩ (< 0...
January 28, 2019: IEEE Transactions on Biomedical Circuits and Systems
Phanit Songvut, Pajaree Chariyavilaskul, Mayuree H Tantisira, Phisit Khemawoot
The aim of this study was to investigate the safety and pharmacokinetic profiles of a newly developed, standardized extract of Centella asiatica (ECa 233) capsule in healthy Thai volunteers. This study was designed as an open-labeled, 2-sequence dosage, single- and repeated-dose study investigated under fasting conditions. Plasma concentrations of the parent compounds and their relative acid metabolites were measured and pharmacokinetic parameters were calculated using noncompartmental analysis. Tolerability was assessed based on physical examinations, monitoring of vital signs, clinical laboratory tests, and any observed adverse events...
January 30, 2019: Planta Medica
Meredith Metcalf, Vassili Glazyrine, Katie Glavin, Alexandra Dahlgren, Carrie Michael, Misty Bechtel, David Bishop, Martin DeRuyter, Moben Mirza, John Taylor, Hadley W Wyre, Jill M Hamilton-Reeves, Jeffrey M Holzbeierlein, Eugene K Lee
PURPOSE: Patients who undergo radical cystectomy for bladder cancer are at high risk of complications and readmissions. Studies indicate insufficient preoperative education and perioperative monitoring. The aim of this study is to demonstrate the feasibility of implementing a health care application to provide more patient education and more thorough monitoring perioperatively. MATERIALS/METHODS: Participants undergoing radical cystectomy with home Wi-Fi access were recruited for this pilot trial...
January 25, 2019: Journal of Urology
Mariska Weenk, Mats Koeneman, Tom H van de Belt, Lucien J L P G Engelen, Harry van Goor, Sebastian J H Bredie
BACKGROUND: Clinical deterioration regularly occurs in hospitalized patients potentially resulting in life threatening events. Early warning scores (EWS), like the Modified Early Warning Score (MEWS), assist care givers in assessing patients' clinical situation, but cannot alert for deterioration between measurements. New devices, like the ViSi Mobile (VM) and HealthPatch (HP) allow for continuous monitoring and can alert deterioration in an earlier phase. VM and HP were tested regarding MEWS calculation compared to nurse measurements, and detection of high MEWS in periods between nurse observations...
January 24, 2019: Resuscitation
Fabrício Tavares Mendonça, Marcelo Cabral de Lucena, Raul Silva Quirino, Catia Sousa Govêia, Gabriel Magalhaes Nunes Guimarães
BACKGROUND: Hypothermia occurs in up to 20% of perioperative patients. Systematic postoperative temperature monitoring is not a standard of care in Brazil and there are few publications about temperature recovery in the postoperative care unit. DESIGN AND SETTING: Multicenter, observational, cross-sectional study, at Hospital de Base do Distrito Federal and Hospital Materno Infantil de Brasília. METHODS: At admission and discharge from postoperative care unit, patients undergoing elective or urgent surgical procedures were evaluated according to tympanic temperature, vital signs, perioperative adverse events, and length of stay in postoperative care unit and length of hospital stay...
January 23, 2019: Revista Brasileira de Anestesiologia
Jan Nedoma, Marcel Fajkus, Radek Martinek, Homer Nazeran
This article presents a solution for continuous monitoring of both respiratory rate (RR) and heart rate (HR) inside Magnetic Resonance Imaging (MRI) environments by a novel ballistocardiography (BCG) fiber-optic sensor. We designed and created a sensor based on the Fiber Bragg Grating (FBG) probe encapsulated inside fiberglass (fiberglass is a composite material made up of glass fiber, fabric, and cured synthetic resin). Due to this, the encapsulation sensor is characterized by very small dimensions (30 × 10 × 0...
January 24, 2019: Sensors
Alyssa Warburton, Ranjan Monga, Venkatesh Sampath, Navin Kumar
BACKGROUND: To examine the correlation between interval vital signs recorded by nursing staff and continuous monitor recordings, and to determine whether aggregated monitor recordings can better predict impending escalation of respiratory support in premature infants. METHOD: Preterm infants on noninvasive respiratory support or room air (RA) were prospectively enrolled. Nursing-and monitor-recorded pulse oximetry (SpO2) and respiratory rates (RR) data were recorded daily...
January 14, 2019: Pediatric Research
Nathan Starliper, Farrokh Mohammadzadeh, Tanner Songkakul, Michelle Hernandez, Alper Bozkurt, Edgar Lobaton
Wearable health monitoring has emerged as a promising solution to the growing need for remote health assessment and growing demand for personalized preventative care and wellness management. Vital signs can be monitored and alerts can be made when anomalies are detected, potentially improving patient outcomes. One major challenge for the use of wearable health devices is their energy efficiency and battery-lifetime, which motivates the recent efforts towards the development of self-powered wearable devices...
January 22, 2019: Sensors
Glen Wright Colopy, Stephen Roberts, David A Clifton
Patients in a hospital step-down unit require a level of care that is between that of the intensive care unit (ICU) and that of the general ward. While many patients remain physiologically stabilized, others will suffer clinical emergencies and be readmitted to the ICU, with a subsequent high risk of mortality. Had the associated physiological deterioration been detected early, the emergency may have been less severe or avoided entirely. Current clinical monitoring is largely heuristic, requiring manual calculation of risk scores and the use of heuristic decision criteria...
January 22, 2019: IEEE Journal of Biomedical and Health Informatics
Sarah Poole, Nigam Shah
Bedside monitors are intended as a safety net in patient care, but their management in the inpatient setting is a significant patient safety concern. The low precision of vital sign alarm systems leads to clinical staff becoming desensitized to the sound of the alarm, a phenomenon known as alarm fatigue. Alarm fatigue has been shown to increase response time to alarms or result in alarms being ignored altogether and has negative consequences for patient safety. We present methods to establish personalized thresholds for heart rate and respiratory rate alarms...
2019: Biomedical Informatics Insights
Nuno Ferreira Monteiro, Patrícia Cipriano, Elga Freire
INTRODUCTION: Acute neurological illness often results in severe disability. Five-year life expectancy is around 40%; half the survivors become completely dependent on outside help. OBJECTIVE: Evaluate the symptoms of patients admitted to a Hospital ward with a diagnosis of stroke, subarachnoid hemorrhage or subdural hematoma, and analyze the role of an In-Hospital Palliative Care Support Team. MATERIAL AND METHODS: Retrospective, observational study with a sample consisting of all patients admitted with acute neurological illness and with a guidance request made to the In-Hospital Palliative Care Support Team of a tertiary Hospital, over 5 years (2012-2016)...
September 2018: Revista da Associação Médica Brasileira
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