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Candida esophagitis in childrens | Page 2

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https://read.qxmd.com/read/16436720/safety-and-pharmacokinetics-of-intravenous-anidulafungin-in-children-with-neutropenia-at-high-risk-for-invasive-fungal-infections
#21
MULTICENTER STUDY
Daniel K Benjamin, Timothy Driscoll, Nita L Seibel, Corina E Gonzalez, Maureen M Roden, Rahki Kilaru, Kay Clark, James A Dowell, Jennifer Schranz, Thomas J Walsh
Anidulafungin is an echinocandin with activity against Candida species and Aspergillus species. Adult dosages under study are 50 mg/day for esophageal candidiasis and 100 mg/day for invasive candidiasis and aspergillosis. Little is known, however, about the safety and pharmacokinetics of anidulafungin in children. A multicenter, ascending-dosage study of neutropenic pediatric patients was therefore conducted. Patients were divided into two age cohorts (2 to 11 years and 12 to 17 years) and were enrolled into sequential groups to receive 0...
February 2006: Antimicrobial Agents and Chemotherapy
https://read.qxmd.com/read/16075235/gastroesophageal-reflux-strictures-in-children-management-and-outcome
#22
A Numanoglu, A J W Millar, R A Brown, H Rode
UNLABELLED: Esophageal reflux (GER) strictures are frequently diagnosed late and require a prolonged management programme depending on the severity of the stricture. Management protocols include medical therapy, bouginage, fundoplication, stricture resection and even interposition grafting. Our preferred method is to delay the anti-reflux surgery until the esophagitis is medically controlled, adequate enteral intake with weight gain is achieved and the oesophageal narrowing adequately dilated...
August 2005: Pediatric Surgery International
https://read.qxmd.com/read/10959741/esophageal-candidiasis-in-pediatric-acquired-immunodeficiency-syndrome-clinical-manifestations-and-risk-factors
#23
C C Chiou, A H Groll, C E Gonzalez, D Callender, D Venzon, P A Pizzo, L Wood, T J Walsh
BACKGROUND: Little is known about the epidemiology and clinical features of esophageal candidiasis (EC) in pediatric AIDS. We therefore investigated the clinical presentation and risk factors of EC in a large prospectively monitored population of HIV-infected children at the National Cancer Institute. PATIENTS AND METHODS: We reviewed the records of all HIV-infected children (N = 448) followed between 1987 and 1995 for a history of esophageal candidiasis to characterize the epidemiology, clinical features, therapeutic interventions and outcome of esophageal candidiasis...
August 2000: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/10835005/correlation-between-in-vitro-and-in-vivo-antifungal-activities-in-experimental-fluconazole-resistant-oropharyngeal-and-esophageal-candidiasis
#24
T J Walsh, C E Gonzalez, S Piscitelli, J D Bacher, J Peter, R Torres, D Shetti, V Katsov, K Kligys, C A Lyman
Oropharyngeal and esophageal candidiasis (OPEC) is a frequent opportunistic mycosis in immunocompromised patients. Azole-resistant OPEC is a refractory form of this infection occurring particularly in human immunodeficiency virus (HIV)-infected patients. The procedures developed by the Antifungal Subcommittee of the National Committee for Clinical Laboratory Standards (NCCLS) are an important advance in standardization of in vitro antifungal susceptibility methodology. In order to further understand the relationship between NCCLS methodology and antifungal therapeutic response, we studied the potential correlation between in vitro susceptibility to fluconazole and in vivo response in a rabbit model of fluconazole-resistant OPEC...
June 2000: Journal of Clinical Microbiology
https://read.qxmd.com/read/9078332/the-role-of-esophagoscopy-in-diagnosis-and-management-of-esophagitis-in-children-with-cancer
#25
D W Isaac, D M Parham, C C Patrick
Esophagitis is a common complication in patients treated for cancer; however, difficulty in determining its etiology on the basis of noninvasive clinical information limits the implementation of specific therapies. We reviewed our experience with esophagoscopy and biopsy as an aid in the diagnosis and management of esophagitis in children with cancer. Of eleven episodes of esophagitis evaluated by esophagoscopy with biopsy, four (36%) had an infectious etiology (two with Candida, one with Herpes simplex virus, and one with viridans streptococci)...
April 1997: Medical and Pediatric Oncology
https://read.qxmd.com/read/8296555/fungal-esophagitis-in-children
#26
C Young, M H Chang, J M Chen
Seven patients were endoscopically diagnosed as having a fungal esophagitis with mycologic or histologic support for the diagnosis from 1979 to 1991 in the Department of Pediatrics, National Taiwan University Hospital. The major causative agent was Candida albicans. Other fungi isolated were Candida Krusei, Trichosporon cutaneum, Trichosporon beigelii, and Rhodotorula rubra, but they all resembled one another under endoscopic examination. The most common presenting symptom was hematemesis, and the lower part of the esophagus was more often involved...
November 1993: Zhonghua Minguo Xiao Er Ke Yi Xue Hui za Zhi [Journal]
https://read.qxmd.com/read/8182902/-fluconazole-therapy-for-pediatric-patients-with-severe-candidal-infections
#27
H Wakiguchi, H Hisakawa, M Sinohara, S Watanabe, T Okada, Y Misaki, T Tomoda, H Morita, T Kurashige
Three children with severe candidal infections were treated with fluconazole (FLCZ). An excellent effect or a partial effect was obtained in each case. Case 1 was a boy with candida esophagitis. He had been treated for relapsed ALL and became febrile with severe swallowing pain. FLCZ was administered intravenously and he became afebrile after 10 days of the therapy. Case 2 was a boy with candida pneumonitis. He had been treated for relapsed ALL and became febrile with diffuse infiltration in chest X-ray. FLCZ was administered intravenously and he became afebrile transiently, though fever and abnormal X-ray shadows reappeared soon and died of pneumonia and leukemic infiltrations...
March 1994: Japanese Journal of Antibiotics
https://read.qxmd.com/read/8182899/-experience-of-fluconazole-granules-and-injection-in-pediatric-patients
#28
H Kamiya, T Ihara, N Yasuda, M Sakurai, M Ito, E Azuma, M Ido, T Nakano
Fluconazole (FLCZ) is an antifungal agent of triazole class and has been proven to be effective against deep-seated mycosis caused by Candida spp., Aspergillus spp. and Cryptococcus spp. This time, as we had an opportunity to use fluconazole granules, a new dosage form of the agent, we investigated its efficacy and safety in children with deep-seated mycosis together with the efficacy of the injectable form of the agent. FLCZ was administered to 6 patients with fungal infections for treatment and 5 compromised hosts with a high risk of fungal infections for evaluation of its prophylactic effect...
March 1994: Japanese Journal of Antibiotics
https://read.qxmd.com/read/7422428/candida-esophagitis-and-laryngitis-in-chronic-mucocutaneous-candidiasis
#29
R H Kobayashi, H M Rosenblatt, J M Carney, W J Byrne, M E Ament, G R Mendoza, J P Dudley, E R Stiehm
Five children (aged 11 to 19 years) with lifelong chronic mucocutaneous candidiasis had 12 episodes of esophageal and/or laryngeal candidiasis documented by endoscopy. Symptoms included hoarseness (8/12), dysphagia (6/12), and hemoptysis (1/12). There was poor correlation between oral lesions and esophageal or laryngeal involvement. On fiberoptic endoscopy, the esophagus was involved alone in four episodes (33%), the larynx in two episodes (17%), and both structures in six episodes (50%). In six of eight instances, the esophagram was nondiagnostic or markedly underestimated the extent of inflammation...
September 1980: Pediatrics
https://read.qxmd.com/read/7060167/-mycotic-esophagitis-a-contribution-to-its-etiology
#30
I Steiner, M Otcenásek
Six cases of mycotic pseudomembrane inflammation of the esophagus formed 0.6% of all the necropsies within observed period. The basic disease was malignant tumour in 5 patients, non-tumorous blood disease in one. Culturally, yeast-like organisms of the genus Candida were proved in all cases. In three cases necrotizing and pseudomembrane inflammation of the larynx developed simultaneously. In the control group cultivation examination of the esophagus and larynx was made in 50 "at risk" patients (children, diabetics and oncologic patients) without any overt mycotic disease...
February 1982: Ceskoslovenská Patologie
https://read.qxmd.com/read/5421899/-candida-esophagitis-in-children-with-malignant-disorders
#31
H J Kaufmann
No abstract text is available yet for this article.
1970: Annales de Radiologie
https://read.qxmd.com/read/5000905/-occurrence-of-thrush-fungi-on-feeding-tubes-following-removal-from-the-upper-intestinal-tract-in-children
#32
H Gemeinhardt, E R Kirchberger
No abstract text is available yet for this article.
1971: Pädiatrie und Grenzgebiete
https://read.qxmd.com/read/3865555/candida-esophagitis-in-two-children-with-acute-leukemia-successful-therapy-with-ketoconazole
#33
S P Rao, M R Hammerschlag, J A Walk
No abstract text is available yet for this article.
1985: American Journal of Pediatric Hematology/oncology
https://read.qxmd.com/read/2594038/survival-in-children-with-perinatally-acquired-human-immunodeficiency-virus-type-1-infection
#34
G B Scott, C Hutto, R W Makuch, M T Mastrucci, T O'Connor, C D Mitchell, E J Trapido, W P Parks
We describe our experience at Jackson Memorial Hospital in Miami, Florida, with 172 children who were given diagnoses of perinatally acquired infection with human immunodeficiency virus type 1 (HIV-1). The 146 mothers of the children acquired HIV-1 through heterosexual contact (69 percent), intravenous drug use (30 percent), or blood transfusion (1 percent). The children presented with symptomatic disease at a median age of eight months; only 21 percent presented after the age of two years. The most common first manifestations of disease were lymphoid interstitial pneumonia (in 17 percent), encephalopathy (in 12 percent), recurrent bacterial infections (in 10 percent), and candida esophagitis (in 8 percent), for which the median survival times from diagnosis were 72, 11, 50, and 12 months, respectively...
December 28, 1989: New England Journal of Medicine
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