Matheus H Tempone, Vladimir P Borges-Martins, Felipe César, Dio Pablo Alexandrino-Mattos, Camila S de Figueiredo, Ícaro Raony, Aline Araujo Dos Santos, Aline Teixeira Duarte-Silva, Mariana Santana Dias, Hércules Rezende Freitas, Elisabeth G de Araújo, Victor Tulio Ribeiro-Resende, Marcelo Cossenza, Hilda P Silva, Roberto P de Carvalho, Ana L M Ventura, Karin C Calaza, Mariana S Silveira, Regina C C Kubrusly, Ricardo A de Melo Reis
The retina is the sensory tissue responsible for the first stages of visual processing, with a conserved anatomy and functional architecture among vertebrates. To date, retinal eye diseases, such as diabetic retinopathy, age-related macular degeneration, retinitis pigmentosa, glaucoma, and others, affect nearly 170 million people worldwide, resulting in vision loss and blindness. To tackle retinal disorders, the developing retina has been explored as a versatile model to study intercellular signaling, as it presents a broad neurochemical repertoire that has been approached in the last decades in terms of signaling and diseases...
January 17, 2024: International Journal of Molecular Sciences