Yuli Shen, Christoph Schmaderer, Andreas Ossadnik, Arianne Hammitzsch, Javier Carbajo-Lozoya, Quirin Bachmann, Vera Bonell, Matthias Christoph Braunisch, Uwe Heemann, Dang Pham, Stephan Kemmner, Georg Lorenz
INTRODUCTION: Due to chronic inflammation, maintenance hemodialysis (MHD) patients continue to show excess mortality. Acetate-free citrate-buffered A concentrates could be a way to improve the biocompatibility of the procedure, reduce chronic inflammation, and thus in the long term improve the prognosis of patients. METHODS: Using a pre-post design (3 months of acetate followed by 3 months of citrate-acidified A concentrates in standard bicarbonate-based dialysate hemodialysis, CiaHD) and linear mixed model analysis in 61 stable HD patients, we assessed the impact of CiaHD on counts and phenotypes of peripheral T cells and monocytes by flow cytometry...
2023: International Journal of Nephrology