Fengyun Sun, Kathleen Desevin, Yu Fu, Shanmathi Parameswaran, Jemma Mayall, Vera Rinaldi, Nils Krietenstein, Artur Manukyan, Qiangzong Yin, Carolina Galan, Chih-Hsiang Yang, Anastasia V Shindyapina, Vadim N Gladyshev, Manuel Garber, John E Schjenken, Oliver J Rando
During mammalian reproduction, sperm are delivered to the female reproductive tract bathed in a complex medium known as seminal fluid, which plays key roles in signaling to the female reproductive tract and in nourishing sperm for their onwards journey. Along with minor contributions from the prostate and the epididymis, the majority of seminal fluid is produced by a somewhat understudied organ known as the seminal vesicle. Here, we report the first single-cell RNA-seq atlas of the mouse seminal vesicle, generated using tissues obtained from 23 mice of varying ages, exposed to a range of dietary challenges...
April 11, 2024: bioRxiv