keyword
https://read.qxmd.com/read/33403621/prognosis-as-health-trajectory-educating-patients-and-informing-the-plan-of-care
#1
EDITORIAL
John M Thomas, Leo M Cooney, Terri R Fried
No abstract text is available yet for this article.
January 5, 2021: Journal of General Internal Medicine
https://read.qxmd.com/read/32427302/cognitive-screening-of-older-practitioners-reply
#2
LETTER
Leo M Cooney, Thomas Balcezak
No abstract text is available yet for this article.
May 19, 2020: JAMA
https://read.qxmd.com/read/32227645/associations-of-social-and-behavioral-determinants-of-health-index-with-self-rated-health-functional-limitations-and-health-services-use-in-older-adults
#3
JOURNAL ARTICLE
Taeho Greg Rhee, Richard A Marottoli, Leo M Cooney, Richard H Fortinsky
OBJECTIVES: To characterize the cumulative risk factors of social and behavioral determinants of health (SDoH) and examine their association with self-rated general health, functional limitations, and use of health services among US older adults. DESIGN: Cross-sectional analysis of the 2013-2014 National Health and Nutrition Examination Survey. SETTING: Nationally representative health interview survey in the United States. PARTICIPANTS: Survey respondents aged 65 or older (n = 1,306 unweighted)...
March 30, 2020: Journal of the American Geriatrics Society
https://read.qxmd.com/read/30964203/functional-outcomes-after-hip-fracture-in-independent-community-dwelling-patients
#4
JOURNAL ARTICLE
Jennifer A Ouellet, Gregory M Ouellet, Alison M Romegialli, Marilyn Hirsch, Lisa Berardi, Christine M Ramsey, Leo M Cooney, Lisa M Walke
OBJECTIVES: To determine predictors of new activities of daily living (ADLs) disability and worsened mobility disability and secondarily increased daily care hours received, in previously independent hip fracture patients. DESIGN: Retrospective cohort study. SETTING: Academic hospital with ambulatory follow-up. PARTICIPANTS: Community-dwelling adults 65 years or older independent in ADLs undergoing hip fracture surgery in 2015 (n = 184)...
July 2019: Journal of the American Geriatrics Society
https://read.qxmd.com/read/30958502/prognosis-reconsidered-in-light-of-ancient-insights-from-hippocrates-to-modern-medicine
#5
JOURNAL ARTICLE
John M Thomas, Leo M Cooney, Terri R Fried
Whereas modern clinicians are often reluctant to discuss prognosis with their patients, such discussions were central to medical practice in ancient Greece. A historical analysis has the potential to explain the reasons for this difference in prognostic practices and provide insights into overcoming current challenges. Many scholars consider prognosis to be the principal scientific achievement of the Hippocratic tradition. The earliest treatise on the subject, On Prognostics, defines prognosis broadly as "foreseeing and foretelling, by the side of the sick, the present, the past, and the future...
June 1, 2019: JAMA Internal Medicine
https://read.qxmd.com/read/28656020/group-a-streptococcal-bacteremia-following-streptococcal-pharyngitis-in-an-older-patient-with-diabetes-a-case-report
#6
JOURNAL ARTICLE
Mehida Alexandre, Ruth Wang'ondu, Leo M Cooney
Group A streptococcus (GAS) is responsible for a wide range of both invasive and noninvasive infections. Severe invasive group A streptococcal infection is associated with morbidity and mortality and has been linked to chronic medical conditions with skin and soft tissues involvement, and intravenous drug use (IVDU). Invasive diseases are, however, rare and have been recognized to affect the extremes of age (younger than 10 years of age and older than 74). We report a case of Group A streptococcus bacteremia following pharyngitis in a 76-year-old diabetic male with no history of IVDU...
June 2017: Yale Journal of Biology and Medicine
https://read.qxmd.com/read/28481412/pioneers-in-geriatrics-passing-it-on
#7
JOURNAL ARTICLE
Leo M Cooney
No abstract text is available yet for this article.
July 2017: Journal of the American Geriatrics Society
https://read.qxmd.com/read/27858982/hip-fracture-can-we-do-better
#8
EDITORIAL
Jennifer A Ouellet, Leo M Cooney
No abstract text is available yet for this article.
January 2017: Journal of the American Geriatrics Society
https://read.qxmd.com/read/27770183/35th-annual-meeting-of-the-european-association-for-the-study-of-diabetes-brussels-belgium-28-september-2-october-1999
#9
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
August 1999: Diabetologia
https://read.qxmd.com/read/27384436/an-epidemiologic-study-on-ageing-and-dysphagia-in-the-acute-care-geriatric-hospitalized-population-a-replication-and-continuation-study
#10
JOURNAL ARTICLE
Steven B Leder, Debra M Suiter, George O Agogo, Leo M Cooney
United States census data project dramatic increases in the geriatric population ageing demographics by 2060 with concomitant health-care consequences. The purpose of this replication and continuation study was to collect new 2014 demographic data relative to ageing, swallow evaluation referral rates, and oral feeding status in geriatric-hospitalized patients for comparison with published data from 2000 to 2007. This was a planned data acquisition study of consecutive hospitalized patients referred for swallow assessments...
October 2016: Dysphagia
https://read.qxmd.com/read/23692412/systematic-review-health-related-characteristics-of-elderly-hospitalized-adults-and-nursing-home-residents-associated-with-short-term-mortality
#11
REVIEW
John M Thomas, Leo M Cooney, Terri R Fried
OBJECTIVES: To identify the domains of health-related characteristics of older hospitalized adults and nursing home residents most strongly associated with short-term mortality. DESIGN: Systematic review. SETTING: Studies published in English in MEDLINE, Scopus, or Web of Science before August 1, 2010. PARTICIPANTS: Prospective studies consisting of persons aged 65 and older that evaluated the association between at least one health-related participant characteristic and mortality within a year in multivariable analysis...
June 2013: Journal of the American Geriatrics Society
https://read.qxmd.com/read/18669948/everyday-decision-making-ability-in-older-persons-with-cognitive-impairment
#12
JOURNAL ARTICLE
James M Lai, Thomas M Gill, Leo M Cooney, Elizabeth H Bradley, Keith A Hawkins, Jason H Karlawish
OBJECTIVE: To demonstrate the reliability and validity of the Assessment of Capacity for Everyday Decision-Making (ACED), an instrument to evaluate everyday decision-making. METHODS: The authors administered the ACED to 39 persons with very mild to moderate cognitive impairment and 13 cognitively intact caregivers. RESULTS: Intraclass correlation coefficients showed good reliability for the measures of understanding, appreciation and reasoning, and Cronbach's alpha coefficients were > or =0...
August 2008: American Journal of Geriatric Psychiatry
https://read.qxmd.com/read/17493198/access-to-primary-care-for-medicare-beneficiaries
#13
JOURNAL ARTICLE
William C Chou, Leo M Cooney, Peter H Van Ness, Heather G Allore, Thomas M Gill
OBJECTIVES: To determine the acceptance rate of new Medicare patients by all primary care physicians. Among primary care physicians accepting new patients, to determine whether demographic and geographic factors are associated with the likelihood of accepting new Medicare patients. DESIGN: Cross-sectional. SETTING: Primary care physicians drawn from a national sample. PARTICIPANTS: Eight hundred forty-eight primary care physicians...
May 2007: Journal of the American Geriatrics Society
https://read.qxmd.com/read/15602063/commentary-the-evolution-of-american-geriatrics
#14
COMMENT
Leo M Cooney
No abstract text is available yet for this article.
November 2004: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://read.qxmd.com/read/15057822/genome-sequence-of-the-brown-norway-rat-yields-insights-into-mammalian-evolution
#15
JOURNAL ARTICLE
Richard A Gibbs, George M Weinstock, Michael L Metzker, Donna M Muzny, Erica J Sodergren, Steven Scherer, Graham Scott, David Steffen, Kim C Worley, Paula E Burch, Geoffrey Okwuonu, Sandra Hines, Lora Lewis, Christine DeRamo, Oliver Delgado, Shannon Dugan-Rocha, George Miner, Margaret Morgan, Alicia Hawes, Rachel Gill, Celera, Robert A Holt, Mark D Adams, Peter G Amanatides, Holly Baden-Tillson, Mary Barnstead, Soo Chin, Cheryl A Evans, Steve Ferriera, Carl Fosler, Anna Glodek, Zhiping Gu, Don Jennings, Cheryl L Kraft, Trixie Nguyen, Cynthia M Pfannkoch, Cynthia Sitter, Granger G Sutton, J Craig Venter, Trevor Woodage, Douglas Smith, Hong-Mei Lee, Erik Gustafson, Patrick Cahill, Arnold Kana, Lynn Doucette-Stamm, Keith Weinstock, Kim Fechtel, Robert B Weiss, Diane M Dunn, Eric D Green, Robert W Blakesley, Gerard G Bouffard, Pieter J De Jong, Kazutoyo Osoegawa, Baoli Zhu, Marco Marra, Jacqueline Schein, Ian Bosdet, Chris Fjell, Steven Jones, Martin Krzywinski, Carrie Mathewson, Asim Siddiqui, Natasja Wye, John McPherson, Shaying Zhao, Claire M Fraser, Jyoti Shetty, Sofiya Shatsman, Keita Geer, Yixin Chen, Sofyia Abramzon, William C Nierman, Paul H Havlak, Rui Chen, K James Durbin, Amy Egan, Yanru Ren, Xing-Zhi Song, Bingshan Li, Yue Liu, Xiang Qin, Simon Cawley, Kim C Worley, A J Cooney, Lisa M D'Souza, Kirt Martin, Jia Qian Wu, Manuel L Gonzalez-Garay, Andrew R Jackson, Kenneth J Kalafus, Michael P McLeod, Aleksandar Milosavljevic, Davinder Virk, Andrei Volkov, David A Wheeler, Zhengdong Zhang, Jeffrey A Bailey, Evan E Eichler, Eray Tuzun, Ewan Birney, Emmanuel Mongin, Abel Ureta-Vidal, Cara Woodwark, Evgeny Zdobnov, Peer Bork, Mikita Suyama, David Torrents, Marina Alexandersson, Barbara J Trask, Janet M Young, Hui Huang, Huajun Wang, Heming Xing, Sue Daniels, Darryl Gietzen, Jeanette Schmidt, Kristian Stevens, Ursula Vitt, Jim Wingrove, Francisco Camara, M Mar Albà, Josep F Abril, Roderic Guigo, Arian Smit, Inna Dubchak, Edward M Rubin, Olivier Couronne, Alexander Poliakov, Norbert Hübner, Detlev Ganten, Claudia Goesele, Oliver Hummel, Thomas Kreitler, Young-Ae Lee, Jan Monti, Herbert Schulz, Heike Zimdahl, Heinz Himmelbauer, Hans Lehrach, Howard J Jacob, Susan Bromberg, Jo Gullings-Handley, Michael I Jensen-Seaman, Anne E Kwitek, Jozef Lazar, Dean Pasko, Peter J Tonellato, Simon Twigger, Chris P Ponting, Jose M Duarte, Stephen Rice, Leo Goodstadt, Scott A Beatson, Richard D Emes, Eitan E Winter, Caleb Webber, Petra Brandt, Gerald Nyakatura, Margaret Adetobi, Francesca Chiaromonte, Laura Elnitski, Pallavi Eswara, Ross C Hardison, Minmei Hou, Diana Kolbe, Kateryna Makova, Webb Miller, Anton Nekrutenko, Cathy Riemer, Scott Schwartz, James Taylor, Shan Yang, Yi Zhang, Klaus Lindpaintner, T Dan Andrews, Mario Caccamo, Michele Clamp, Laura Clarke, Valerie Curwen, Richard Durbin, Eduardo Eyras, Stephen M Searle, Gregory M Cooper, Serafim Batzoglou, Michael Brudno, Arend Sidow, Eric A Stone, J Craig Venter, Bret A Payseur, Guillaume Bourque, Carlos López-Otín, Xose S Puente, Kushal Chakrabarti, Sourav Chatterji, Colin Dewey, Lior Pachter, Nicolas Bray, Von Bing Yap, Anat Caspi, Glenn Tesler, Pavel A Pevzner, David Haussler, Krishna M Roskin, Robert Baertsch, Hiram Clawson, Terrence S Furey, Angie S Hinrichs, Donna Karolchik, William J Kent, Kate R Rosenbloom, Heather Trumbower, Matt Weirauch, David N Cooper, Peter D Stenson, Bin Ma, Michael Brent, Manimozhiyan Arumugam, David Shteynberg, Richard R Copley, Martin S Taylor, Harold Riethman, Uma Mudunuri, Jane Peterson, Mark Guyer, Adam Felsenfeld, Susan Old, Stephen Mockrin, Francis Collins
The laboratory rat (Rattus norvegicus) is an indispensable tool in experimental medicine and drug development, having made inestimable contributions to human health. We report here the genome sequence of the Brown Norway (BN) rat strain. The sequence represents a high-quality 'draft' covering over 90% of the genome. The BN rat sequence is the third complete mammalian genome to be deciphered, and three-way comparisons with the human and mouse genomes resolve details of mammalian evolution. This first comprehensive analysis includes genes and proteins and their relation to human disease, repeated sequences, comparative genome-wide studies of mammalian orthologous chromosomal regions and rearrangement breakpoints, reconstruction of ancestral karyotypes and the events leading to existing species, rates of variation, and lineage-specific and lineage-independent evolutionary events such as expansion of gene families, orthology relations and protein evolution...
April 1, 2004: Nature
https://read.qxmd.com/read/14980985/who-can-stay-at-home-assessing-the-capacity-to-choose-to-live-in-the-community
#16
JOURNAL ARTICLE
Leo M Cooney, Gary J Kennedy, Keith A Hawkins, Sally Balch Hurme
While the courts have final responsibility, physicians are often asked to evaluate the ability of an older individual to remain living alone in the community. A person's capacity to make this decision can be more difficult to assess than the capacity to make medical decisions. Unsafe actions alone do not restrict the choice of individuals. Inability to understand the implications of these actions may also limit this choice. Decision-making ability is not well measured by global tests of cognitive function. Deficits in executive function resulting in impaired insight, problem-solving ability, and goal-directed planning limit one's ability to make and carry out decisions...
February 23, 2004: Archives of Internal Medicine
https://read.qxmd.com/read/11129764/the-hospital-elder-life-program-a-model-of-care-to-prevent-cognitive-and-functional-decline-in-older-hospitalized-patients-hospital-elder-life-program
#17
JOURNAL ARTICLE
S K Inouye, S T Bogardus, D I Baker, L Leo-Summers, L M Cooney
OBJECTIVES: To describe the Hospital Elder Life Program, a new model of care designed to prevent functional and cognitive decline of older persons during hospitalization. PROGRAM STRUCTURE AND PROCESS: All patients aged > or =70 years on specified units are screened on admission for six risk factors (cognitive impairment, sleep deprivation, immobility, dehydration, vision or hearing impairment). Targeted interventions for these risk factors are implemented by an interdisciplinary team-including a geriatric nurse specialist, Elder Life Specialists, trained volunteers, and geriatricians--who work closely with primary nurses...
December 2000: Journal of the American Geriatrics Society
https://read.qxmd.com/read/10053175/a-multicomponent-intervention-to-prevent-delirium-in-hospitalized-older-patients
#18
COMPARATIVE STUDY
S K Inouye, S T Bogardus, P A Charpentier, L Leo-Summers, D Acampora, T R Holford, L M Cooney
BACKGROUND: Since in hospitalized older patients delirium is associated with poor outcomes, we evaluated the effectiveness of a multicomponent strategy for the prevention of delirium. METHODS: We studied 852 patients 70 years of age or older who had been admitted to the general-medicine service at a teaching hospital. Patients from one intervention unit and two usual-care units were enrolled by means of a prospective matching strategy. The intervention consisted of standardized protocols for the management of six risk factors for delirium: cognitive impairment, sleep deprivation, immobility, visual impairment, hearing impairment, and dehydration...
March 4, 1999: New England Journal of Medicine
https://read.qxmd.com/read/7977922/predictors-of-mortality-and-institutionalization-after-hip-fracture-the-new-haven-epese-cohort-established-populations-for-epidemiologic-studies-of-the-elderly
#19
JOURNAL ARTICLE
R A Marottoli, L F Berkman, L Leo-Summers, L M Cooney
OBJECTIVES: Hip fractures can have devastating effects on the lives of older individuals. We determined the frequency of occurrence of hip fracture and the baseline factors predicting death and institutionalization at 6 months after hip fracture. METHODS: A representative cohort of 2812 individuals aged 65 years and older was followed prospectively for 6 years. Hip fractures were identified, and the occurrence of death and institutionalization within 6 months of the fracture was determined...
November 1994: American Journal of Public Health
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