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Kenny Vlaemynck, Lies Lahousse, Aude Vanlander, Hubert Piessevaux, Pieter Hindryckx
BACKGROUND:  The first-line approach to the treatment of biliary leaks is endoscopic retrograde cholangiopancreatography. A variety of techniques can be used, including sphincterotomy, stenting, a combination of both techniques, or nasobiliary drainage. We performed a systematic review with meta-analysis to define the optimal strategy. METHODS:  We searched MEDLINE/PubMed, EMBASE, CENTRAL, Scopus, Google Scholar, and Web of Science until January 2018 for randomized clinical trials, case-control studies, and prospective cohort studies...
February 13, 2019: Endoscopy
Abel-Jan Tasman
The reconstruction of the nasal dorsum after a hump resection is challenging if narrowing of the nose is to be avoided, the nasal skin is very thin, and the nasal bones are short. This report describes the replacement of the bony and cartilaginous nasal dorsum after resection with an anatomically shaped dorsal replacement graft of diced cartilage in fibrin glue. The technique is illustrated with a clinical case and sonographic morphometry of the nasal dorsum and tip. A modification of the diced cartilage glue graft for thin-skinned patients is presented...
February 2019: Facial Plastic Surgery: FPS
Enrico Robotti, Waldemar Brandao Penna
Rhinoplasty is universally considered as the most demanding procedure in facial plastic surgery. Secondary rhinoplasty is its crown jewel, even more complex, and likewise highly fascinating. The evolution of thought and practice in rhinoplasty in the last decades has been quick and steady, progressively acknowledging the importance of maintaining structure in primary rhinoplasty and rebuilding structure in secondary procedures. No longer is the paradigm to achieve a small, thin, and pointy nose, but rather a well-proportioned nose which looks natural, albeit elegant and breathing well...
February 2019: Facial Plastic Surgery: FPS
Thomas Hildebrandt, Jan Joris Brüning, Hans Lamecker, Stefan Zachow, Werner J Heppt, Nora Schmidt, Leonid Goubergrits
Successful functional surgery on the nasal framework requires reliable and comprehensive diagnosis. In this regard, the authors introduce a new methodology: Digital Analysis of Nasal Airflow (diANA). It is based on computational fluid dynamics, a statistical shape model of the healthy nasal cavity and rhinologic expertise. diANA necessitates an anonymized tomographic dataset of the paranasal sinuses including the complete nasal cavity and, when available, clinical information. The principle of diANA is to compare the morphology and the respective airflow of an individual nose with those of a reference...
February 2019: Facial Plastic Surgery: FPS
Wataru Ito, Alexei Morozov
Observing fear in others (OF) is a form of social stress. In mice, it enhances inhibitory avoidance learning and causes the formation of silent synapses in the prefrontal-amygdala pathway. Here, we report that OF made that pathway prone to facilitation both ex vivo and in vivo. Ex vivo, OF enabled induction of long-term potentiation (LTP), expressed mostly postsynaptically and occluded by inhibitory avoidance training. In vivo, OF enabled facilitation of the dmPFC-BLA pathway by inhibitory avoidance training...
February 13, 2019: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
Lara Rzesnitzek, Marwan Hariz, Joachim K Krauss
In order to shed light on the first application of human functional stereotactic neurosurgery, whether it was in the realm of movement disorders, as has been claimed repeatedly, or in the realm of psychiatry, a review of the original scholarly literature was conducted. Tracking and scrutinising original publications by Spiegel and Wycis, the pioneers of human stereotactic neurosurgery, it was found that its origin and the very incentive for its development and first clinical use were to avoid the side effects of frontal leucotomy...
February 13, 2019: Stereotactic and Functional Neurosurgery
I-Hao Cheng, Jacquie McBride, Miriam Decker, Therese Watson, Hannah Jakubenko, Alana Russo
It is important to address the health needs of asylum seekers within the early stages of their arrival in Australia, as this impacts all aspects of their resettlement. However, asylum seekers face a range of barriers to accessing timely and appropriate health care in the community. In 2012, the increasing number of asylum seekers in Australia placed additional demand on health and social services in high-settlement regions. Health providers experienced a substantial increase in Medicare ineligible clients and avoidable presentations to Emergency Departments, and the health needs of new asylum seeker arrivals were not being fully addressed...
February 14, 2019: Australian Journal of Primary Health
Diego Pulzatto Cury, Bárbara Tavares Schäfer, Sonia Regina Yokomizo de Almeida, Marta Maria da Silva Righetti, Ii-Sei Watanabe
BACKGROUND: The prolonged tendon-healing process, the high costs associated with treatment, the increase in the number of injuries over the past decades, and the lack of consensus on the optimal treatment of tendon injuries are a global problem. Restoring the normal tendon anatomy and decreasing the healing time are key factors for treatment advancement. HYPOTHESIS: Application of a purified protein from natural latex (PPNL) accelerates the healing process, increasing collagen synthesis and decreasing metalloproteinases...
February 13, 2019: American Journal of Sports Medicine
Aisha Egolf, Christina Hartmann, Michael Siegrist
New food technologies have a high potential to transform the current resource-consuming food system to a more efficient and sustainable one, but public acceptance of new food technologies is rather low. Such an avoidance might be maintained by a deeply preserved risk avoidance system called disgust. In an online survey, participants (N = 313) received information about a variety of new food technology applications (i.e., genetically modified meat/fish, edible nanotechnology coating film, nanotechnology food box, artificial meat/milk, and a synthetic food additive)...
February 13, 2019: Risk Analysis: An Official Publication of the Society for Risk Analysis
Benjamin D Chambers, Tracy C Leskey, Annie R Pearce, Thomas P Kuhar
Overwintering brown marmorated stink bugs (Halyomorpha halys) (Stål) are a notable domestic nuisance. In addition to disruptive activity, dead individuals remain in homes, sometimes in large numbers. To better understand the effects of these remains on overwintering behavior, adult H. halys were subjected to several experiments to test their responses to dead conspecifics. In non-tactile tests of individuals exposed to groups of dead conspecifics, H. halys did not respond to 1-yr-old desiccated dead conspecifics, but avoided corpses that were freshly killed...
February 13, 2019: Journal of Economic Entomology
Nadine van Westrhenen, Elzette Fritz, Adri Vermeer, Paul Boelen, Rolf Kleber
AIM: To evaluate the feasibility and effect of a 10-session creative arts in psychotherapy group programme on posttraumatic stress symptoms, behavioural problems, and posttraumatic growth, in children who experienced a traumatic event. DESIGN: A multicentre non-randomized controlled trial with a treatment and a control condition conducted in South Africa (4 sites). METHODS: 125 children aged 7 to 13 years were assigned either to the treatment condition receiving creative arts in psychotherapy or a control condition with a low-level supportive programme without treatment...
2019: PloS One
Tanvir M Huda, Morseda Chowdhury, Shams El Arifeen, Michael J Dibley
INTRODUCTION: Improving maternal health remains one of the targets of sustainable development goals. A maternal death can occur at any time during pregnancy, but delivery is by far the most dangerous time for both the woman and her baby. Delivery at a health facility can avoid most maternal deaths occurring from preventable obstetric complications. The influence of both individual and community factors is critical to the use of health facility delivery services. In this study, we aim to examine the role of individual and community factors associated with health facility-based delivery in Bangladesh...
2019: PloS One
Danielle Weiss, Sarah Ostrowski-Delahanty, Jason Van Allen, Paige Seegan, Meghan L Marsac
PURPOSE: Nurses are at the forefront of children's postinjury recovery; this unique role provides an opportunity for nurses to recognize and screen for symptoms that may interfere with children's quality of life (QOL). As such, aims of the present investigation were to explore selected variables (e.g., posttraumatic stress symptoms [PTSS], hope) that have the potential to impact QOL after pediatric injury, with a larger goal of contributing to recommendations for nursing practice to support children's full (physical and emotional) recovery during the peritrauma period following injury...
February 13, 2019: Journal for Specialists in Pediatric Nursing: JSPN
Kamryn T Eddy, Stephanie G Harshman, Kendra R Becker, Elana Bern, Rachel Bryant-Waugh, Anja Hilbert, Debra K Katzman, Elizabeth A Lawson, Laurie D Manzo, Jessie Menzel, Nadia Micali, Rollyn Ornstein, Sarah Sally, Sharon P Serinsky, William Sharp, Kathryn Stubbs, B Timothy Walsh, Hana Zickgraf, Nancy Zucker, Jennifer J Thomas
OBJECTIVE: Since its introduction to the psychiatric nomenclature in 2013, research on avoidant/restrictive food intake disorder (ARFID) has proliferated highlighting lack of clarity in how ARFID is defined. METHOD: In September 2018, a small multi-disciplinary pool of international experts in feeding disorder and eating disorder clinical practice and research convened as the Radcliffe ARFID workgroup to consider operationalization of DSM-5 ARFID diagnostic criteria to guide research in this disorder...
February 13, 2019: International Journal of Eating Disorders
Karthik Shekhar, Vilas Menon
Unprecedented technological advances in single-cell RNA-sequencing (scRNA-seq) technology have now made it possible to profile genome-wide expression in single cells at low cost and high throughput. There is substantial ongoing effort to use scRNA-seq measurements to identify the "cell types" that form components of a complex tissue, akin to taxonomizing species in ecology. Cell type classification from scRNA-seq data involves the application of computational tools rooted in dimensionality reduction and clustering, and statistical analysis to identify molecular signatures that are unique to each type...
2019: Methods in Molecular Biology
Yasuhiro Otsuki, Tetsuhiko Go, Sung Soo Chang, Natsumi Matsuura, Hiroyasu Yokomise
The anatomy of pulmonary vessels varies. The right upper pulmonary vein usually drains in front of the pulmonary artery to the left atrium. We herein describe a case of the right upper lobe pulmonary vein draining posterior to the pulmonary artery and absent right upper lobe pulmonary vein in the ventral hilum. A 64-year-old woman suspected to have lung cancer and scheduled for surgery underwent pre-operative three-dimensional computed tomography (3D-CT), which revealed that pulmonary vessels V1 + 3 and V2 drain posteriorly to the pulmonary artery...
February 13, 2019: General Thoracic and Cardiovascular Surgery
Hanna Czajka, Szymon Czajka, Katarzyna Anna Dyląg, Elżbieta Borek, Ernest Kuchar
A worrying increase in the number of measles cases has been noted recently in Poland, which may have to do with a decreasing proportion of children vaccinated against measles, mumps, and rubella (MMR) in the second year of life (<95%). For many years, MMR vaccination in children has been associated with a fear of allergy to eggs. This study seeks to define the reason and justification for postponing MMR vaccination in a population of children referred to the outpatient specialist immunization clinic. One hundred and thirty eight (138) children, mean 24...
February 14, 2019: Advances in Experimental Medicine and Biology
Johannes Kraft, Jaap Zindler, Giuseppe Minniti, Matthias Guckenberger, Nicolaus Andratschke
PURPOSE OF REVIEW: To give an overview on the current evidence for stereotactic radiosurgery of brain metastases with a special focus on multiple brain metastases. RECENT FINDINGS: While the use of stereotactic radiosurgery in patients with limited brain metastases has been clearly defined, its role in patients with multiple lesions (> 4) is still a matter of controversy. Whole-brain radiation therapy (WBRT) has been the standard treatment approach for patients with multiple brain lesions and is still the most commonly used treatment approach worldwide...
February 13, 2019: Current Treatment Options in Neurology
Yong Wang, Zhen Zeng, Tian-Lei Liu, Ling Sun, Qin Yao, Ke-Ping Chen
Genomes can be considered a combination of 16 dinucleotides. Analysing the relative abundance of different dinucleotides may reveal important features of genome evolution. In present study, we conducted extensive surveys on the relative abundances of dinucleotides in various genomic components of 28 bacterial, 20 archaean, 19 fungal, 24 plant and 29 animal species. We found that TA, GT and AC are significantly under-represented in open reading frames of all organisms and in intergenic regions and introns of most organisms...
February 13, 2019: Molecular Genetics and Genomics: MGG
P Lebert, O Ernst, M Zins
PURPOSE: To present radiological aspects of jejunoileal diverticulosis and its complications. RESULTS: Jejunoileal diverticulosis is a relatively rare and underestimated condition, which mostly affects the elderly. It is frequently asymptomatic but it can lead to significant complications requiring surgical treatment. Jejunoileal diverticulosis is far less common than colonic diverticulosis. Acquired small bowel diverticula are often numerous but the complication rate is low...
February 13, 2019: Abdominal Radiology
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