Dimitrios Kanakopoulos, Hester Lacey, Anna Payne, Maria Houlihan, Harjoat Riyat, Rhys Wheelan, Jonathan Cubitt, Joshua P Totty
BACKGROUND: Merkel cell carcinoma (MCC) is a rare cutaneous malignancy with high metastatic potential. Sentinel lymph node biopsy (SLNB) is used to assess locoregional spread, facilitate staging, and inform prognosis. Positive nodal status is associated with higher recurrence rates and reduced overall survival. METHODS: A systematic search was conducted. Eligible articles included patients diagnosed with MCC, who would be candidates for or who had SLNB. The Covidence tool was used for screening and data extraction, including additional treatments, disease-free survival, overall survival, and recurrence...
April 2024: Plastic and Reconstructive Surgery. Global Open