Zejun Li, Shouhuan Liu, Qiuxia Wu, Jing Li, Qian Yang, Xin Wang, Pu Peng, Qianjin Wang, Yueheng Liu, Manyun Li, Yuzhu Hao, Huixue Xu, Li He, Yunfei Wang, Shubao Chen, Tieqiao Liu
INTRODUCTION: Major depressive disorder (MDD) is a highly prevalent and burdensome condition. This study aims to evaluate the effectiveness, tolerability, and safety of vortioxetine in treating MDD based on real-world data. METHODS: A systematic search of eight electronic databases was performed from inception until October 2022 to identify real-world studies, excluding randomized controlled trials. We conducted subgroup, meta-regression, sensitivity analyses, publication bias and quality assessments using the random-effects model...
April 27, 2023: International Journal of Neuropsychopharmacology