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Cancer Urinary Bladder In Surgery

Christopher J Micallef, Jamie N Johnson, R Michael Johnson
In the USA, external beam radiation is offered to patients as an alternative to surgery for non-melanoma skin cancers. While this technique may be useful in highly specific patient populations, recalcitrant chronic radiation wounds can result. These complex wounds ultimately may require major reconstructive surgery to achieve closure. Porcine urinary bladder matrix (UBM) may be effective in the treatment of radiation wounds and eliminating the need for vascularized tissue transfers. A case report of an elderly male with bilateral radiation wounds of the lower extremity, one extremity treated with free flap reconstruction and the other with porcine urinary bladder matrix, is presented...
March 2019: Journal of Surgical Case Reports
Nguyen Van De, Truong La, Pham Ngoc Minh, Pham Thi Bich Dao, Le Van Duyet
Introduction: Schistosoma lives as a parasite in the portal vein causing intestinal lesions. It also lives in the liver, spleen, and the vein of the urinary bladder causing lesions in the urinary system. Angola is an endemic area of Schistosoma haematobium , which causes lesions in the urinary system, including the urinary bladder. In this study, we aimed to identify and classify the parasites that were collected from four patients from Angola, who currently live in Vietnam, by morphological and molecular methods...
2019: Infection and Drug Resistance
Carmit K McMullen, Marilyn L Kwan, Janice C Colwell, Julie R Munneke, James V Davis, Alison Firemark, Neon Brooks, Marcia Grant, Scott M Gilbert, Andrea Altschuler
Background: Bladder cancer patients who undergo cystectomy and urinary diversion face functional and quality-of-life challenges. Little is known about these patients' experiences during decision-making, surgery, and recovery, or how they vary by treatment setting. Objective: To learn about patients' experiences with treatment choice, surgical care, and recovery across health settings. Understanding patient experiences is essential to closing care gaps and developing patient-reported measures...
January 31, 2019: Bladder Cancer
Takefumi Yoshida, Dai Shida, Hirokazu Taniguchi, Shunsuke Tsukamoto, Yukihide Kanemitsu
BACKGROUND: Two procedures widely performed to treat locally advanced colorectal cancer adherent to the urinary bladder are total cystectomy (as part of pelvic exenteration) and partial cystectomy; however, little is known about outcomes following partial cystectomy. METHODS: A retrospective database of patients with colorectal cancer involving the urinary bladder who underwent R0 or R1 resection at our institution from 2001 to 2015 was constructed. The histological extent of bladder invasion and long-term outcomes were examined...
March 7, 2019: Annals of Surgical Oncology
Nikoletta K Pianou, Petros Z Stavrou, Evangelia Vlontzou, Phivi Rondogianni, Demetrios N Exarhos, Ioannis E Datseris
Prostate cancer (PCa) is the most common solid cancer affecting men worldwide. Serum prostate-specific antigen (PSA) is at present the most commonly used biomarker for PCa screening, as well as a reliable marker of disease recurrence after initial treatment. Bone metastases (BM) are present in advanced stages of the disease. Imaging of BM is important not only for localization and characterization, but also to evaluate their size and number, as well as to follow-up the disease during and after therapy. Bone metastases formation is triggered by cancer initiating cells in the bone marrow and is facilitated by the release of several growth factors...
March 5, 2019: Hellenic Journal of Nuclear Medicine
Seyed Hossein Hosseini Sharifi, Abbas Basiri
INTRODUCTION: Vesico-urethral anastomosis (VUA) represents a challenging step of Open Radical Prostatectomy (ORP) because of limitation of space in the depth of men's pelvis, lack of control on knots during tightening and subsequent inadequate coupling of VUA or breakdown of knots and extremely difficult reapplication of sutures. To facilitate this step of RP we have developed a simple and reproducible technique and report our 8 years' experience. TECHNIQUE:  We used two extra-long DeBakey tissue forceps to approximate the bladder neck to the urethral stump...
February 26, 2019: Urology Journal
Abhishek Shankar, Jaineet Patil, Niharika Sethi, Abhijit Chakraborty, Sachidanand Jee Bharati, Kavita Mandrelle, Anil Luther, Ruchir Bhandari, Goura Kishor Rath
Background: Carcinoma cervix is the second most common type of cancer in the world. With the increasing proportion of women surviving carcinoma of the cervix, quality of life has been an important clinical issue. Since there are very few studies from India, this study is to assess urinary dysfunction issues in patients of carcinoma cervix treated with multimodality therapy using the LENT SOMA scores. Methods: The study was prospective and patients treated between 1995 - 2007 on follow up were included in this study after ethical clearance...
February 26, 2019: Asian Pacific Journal of Cancer Prevention: APJCP
Yuelin Li, Bruce Rapkin, Thomas M Atkinson, Elizabeth Schofield, Bernard H Bochner
PURPOSE: As we begin to leverage Big Data in health care settings and particularly in assessing patient-reported outcomes, there is a need for novel analytics to address unique challenges. One such challenge is in coding transcribed interview data, typically free-text entries of statements made during a face-to-face interview. Latent Dirichlet Allocation (LDA) offers statistical rigor and consistency in automating the interpretation of patients' expressed concerns and coping strategies...
February 23, 2019: Quality of Life Research
Michael A Feuerstein, Leah Goldstein, Brieyona Reaves, Arony Sun, Michael Goltzman, Bradley A Morganstern, Ahmad Shabsigh, Dean F Bajorin, Jonathan E Rosenberg, S Machele Donat, Harry W Herr, Vincent P Laudone, Thomas M Atkinson, Yuelin Li, Guido Dalbagni, Bruce Rapkin, Bernard H Bochner
PURPOSE: To evaluate patient-reported outcomes (PROs) for bladder cancer patients undergoing neoadjuvant chemotherapy (NAC) prior to radical cystectomy (RC) using longitudinal data and propensity-matched scoring analyses. METHODS: 155 patients with muscle-invasive bladder cancer scheduled for RC completed the European Organization for Research and Treatment of Cancer questionnaires, EORTC QLQ-C30, EORTC QLQ-BLM30, Fear of Recurrence Scale, Mental Health Inventory and Satisfaction with Life Scale within 4 weeks of surgery...
February 23, 2019: World Journal of Urology
Masaru Nakamura, Kyoko Tanaka, Shigenori Hayashi, Tohru Morisada, Takashi Iwata, Nobuaki Imanishi, Daisuke Aoki
OBJECTIVES: Radical hysterectomy is performed for invasive cervical cancer. In this surgery, separation of the anterior leaf and posterior leaves of the vesicouterine ligament (VUL) is important. We studied the local anatomy of the anterior leaf of the VUL, especially the branches of the umbilical artery from the view point of surgery and cadaver dissection. STUDY DESIGN: We observed the cervicovesical blood vessels and the connective tissue layer continued from umbilical artery and searched for the origin of the cervicovesical blood vessels in radical hysterectomy...
February 16, 2019: European Journal of Obstetrics, Gynecology, and Reproductive Biology
François Audenet, Kyrollis Attalla, Morgane Giordano, John Pfail, Marc A Lubin, Nikhil Waingankar, Daniel Gainsburg, Ketan K Badani, Alan Sim, John P Sfakianos
OBJECTIVES: To evaluate the feasibility and outcomes of a nonopioid (NOP) perioperative pain management protocol for patients undergoing robot-assisted radical cystectomy (RARC). MATERIALS AND METHODS: We prospectively included 52 consecutive patients undergoing RARC at our institution for bladder cancer. Patients received a multimodal pain management protocol, including a combination of nonopioid pain medications and regional anesthesia. For comparison, we retrospectively included 41 consecutive patients who received the same procedure before implementation of the NOP protocol...
February 15, 2019: Urologic Oncology
T N Musayev, F A Guliev
AIM: To investigate the rates, types and risk factors for intraoperative complications in patients with bladder cancer undergoing radical cystectomy with various types of urinary diversions. MATERIAL AND METHODS: The study comprised 257 patients, including 241 (93.8%) men and 16 (6.2%) women who underwent radical cystectomy. The mean age of the patients was 58.5 (37-81) years. The analysis included intraoperative blood loss and blood transfusion, the rates of vascular, rectum and nerve injury, and operative time as a function of type of urinary diversion and cystectomy, the type of surgery, tumor stage (pT and pN), body mass index, and the total number of radical cystectomies performed by the surgical team...
October 2018: Urologii︠a︡
Fatai Oluyadi, Preethi Ramachandran, Vladmir Gotlieb
Female urethral diverticular cancer is a very rare entity with only around 100 cases reported so far in literature and accounts for <1% of all malignancies. In this article, we present a 47-year-old African American female with repeated hospital visits for urinary retention, hematuria, and urinary tract infections. Initial computed tomography imaging and cystoscopy was unremarkable except for a distended urinary bladder. Subsequent magnetic resonance imaging and corresponding cystoscopy eventually indicated the presence of a urethral diverticulum...
January 2019: Journal of Investigative Medicine High Impact Case Reports
Jessica A Lavery, Allison Lipitz-Snyderman, Diane G Li, Peter B Bach, Katherine S Panageas
PURPOSE: Medicare claims provide a rich data source for large-scale quality assessment because data are available for all beneficiaries nationally. For cancer surgery, the absence of information regarding site of cancer and date of diagnosis on an administrative claim necessitates testing to ensure accurate quality assessment and public reporting. METHODS: Using the SEER Medicare-linked database as the gold standard, we developed and tested an approach to identify cancer-directed surgeries from Medicare fee-for-service claims alone...
February 2019: JCO Clinical Cancer Informatics
Christer Groeben, Rainer Koch, Martin Baunacke, Angelika Borkowetz, Manfred P Wirth, Johannes Huber
BACKGROUND: Radical cystectomy (RC) still poses a significant risk for mortality and morbidity. OBJECTIVES: We compared in-hospital outcomes after RC in the United States and -Germany using population-based data. METHODS: We compared data from the US Nationwide Inpatient Sample to the German hospital billing database. Mortality and transfusion during hospital stay and length of stay (LOS) were evaluated. RESULTS: In all, 17,711 (the United States) and 60,447 (-Germany) cases were included...
January 30, 2019: Urologia Internationalis
Gen Tsujio, Hisashi Nagahara, Masatsune Shibutani, Tatsunari Fukuoka, Shinji Matsutani, Chikako Kusunoki, Sadaaki Yamazoe, Kenjiro Kimura, Takahiro Toyokawa, Ryosuke Amano, Hiroaki Tanaka, Kazuya Muguruma, Masakazu Yashiro, Kosei Hirakawa, Masaichi Ohira
A 73-year-old woman presented to her doctor because of lower abdominal pain and distension. A neoplastic lesion in the lower abdomen was revealed, and she was referred to our department. Enhanced CT showed wall thickening in the urinary bladder and a 6 cm mass that extended to the appendix. An appendiceal tumor invading the urinary bladder or a urinary bladder tumor invading the appendix was suspected, and we planned surgical treatment. One month later, we repeated enhanced CT scanning on admission. The mass had shrunk, but the thickening of the urinary bladder wall remained, and an enhanced appendiceal tumor was visible...
December 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Takuya Koie, Chikara Ohyama, Kazuhide Makiyama, Toru Shimazui, Tomoaki Miyagawa, Kosuke Mizutani, Tomohiro Tsuchiya, Taku Kato, Keita Nakane
Radical cystectomy remains the gold standard for treatment of muscle-invasive bladder. Robot-assisted radical cystectomy has technical advantages over laparoscopic radical cystectomy and has emerged as an alternative to open radical cystectomy. Despite the advancements in robotic surgery, experience with total intracorporeal reconstruction of urinary diversion remains limited. Most surgeons have carried out the hybrid approach of robot-assisted radical cystectomy and extracorporeal reconstruction of urinary diversion, as intracorporeal reconstruction of urinary diversion remains technically challenging...
January 28, 2019: International Journal of Urology: Official Journal of the Japanese Urological Association
Jeffrey C Loh-Doyle
PURPOSE OF REVIEW: After radical cystoprostatectomy, patients often develop erectile dysfunction refractory to first- and second-line treatments. In this review, we summarize and analyze the literature describing the technical considerations and outcomes of penile implant surgery in bladder cancer patients with history of radical cystectomy and urinary diversion. RECENT FINDINGS: Penile prosthesis surgery in patients after radical cystectomy and urinary diversion has been infrequently described in the literature...
January 28, 2019: Current Urology Reports
Martin Lovecek, Marketa Janatova, Pavel Skalicky, Tomas Zemanek, Roman Havlik, Jiri Ehrmann, Ondrej Strouhal, Petra Zemankova, Klara Lhotova, Marianna Borecka, Jana Soukupova, Hana Svebisova, Pavel Soucek, Viktor Hlavac, Zdenek Kleibl, Cestmir Neoral, Bohuslav Melichar, Beatrice Mohelnikova-Duchonova
Background: The principal aim of this report was to study second primary malignant neoplasms (SMNs) in long-term survivors of pancreatic ductal adenocarcinoma (PDAC) with regard to the germline genetic background. Patients and methods: A total of 118 PDAC patients after a curative-intent surgery who were treated between 2006 and 2011 were analyzed. Of the 22 patients surviving for >5 years, six went on to develop SMNs. A genetic analysis of 219 hereditary cancer-predisposition and candidate genes was performed by targeted next-generation sequencing in germline DNA from 20 of these patients...
2019: Cancer Management and Research
Jeffrey C Loh-Doyle, Akbar Ashrafi, Azadeh Nazemi, Saum Ghodoussipour, Eli Thompson, Kevin Wayne, Stuart D Boyd
OBJECTIVES: To determine the impact of radical cystectomy and orthotopic neobladder (NB) diversion on device-related outcomes in patients who undergo subsequent placement of both, an artificial urinary sphincter (AUS) and 3-piece inflatable penile prosthesis. MATERIALS AND METHODS: Using an institutional prosthetic database, we identified 39 patients who underwent radical cystectomy and NB and subsequent implantation of both prosthetic devices from 2003 to 2017...
January 18, 2019: Urology
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