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Dermatology guidelines

Susanne Darr-Foit, Peter Elsner, Jörg Tittelbach
The term "deprescribing" refers to the systematic process of identifying, tapering, and discontinuing individually ineffective and/or potentially harmful drugs. Considering various aspects, the present review addresses the concept of "deprescribing" in the context of recommendations for use of systemic drugs contained in current dermatological guidelines. Overall, 16 sets of guidelines developed under the auspices of the German Society of Dermatology (DDG) were reviewed. Our analysis shows that many guidelines contain no or insufficient information in terms of deprescribing systemic drugs...
February 13, 2019: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Lenka Krbková, Kateřina Kybicová, Dušan Pícha, Hana Roháčová, Dita Smíšková
The national guideline aims to highlight the latest knowledge about clinical manifestations of the infection, to summarize the diagnostic algorithm and to recommend the appropriate antibiotic therapy with respect to evidence-based medicine. The recommendations are consistent with most European guidelines as well as those published by the IDSA. The guideline provides the most recent information on the epidemiology, etiology and pathogenesis of Lyme borreliosis, dermatological, neurological and musculoskeletal involvement, the appropriate diagnostic procedure and prevention...
September 2018: Klinická Mikrobiologie a Infekc̆ní Lékar̆ství
Kate Hopkinson
Chronic spontaneous urticaria (CSU) is a debilitating condition that can substantially affect patients' quality of life (QoL), mental health and ability to perform daily tasks. International guidelines on the management of CSU, jointly developed by the European Academy of Allergy and Clinical Immunology (EAACI), Global Allergy and Asthma European Network (GA2 LEN), European Dermatology Forum (EDF) and World Allergy Organization (WAO), recommend a treat-to-target strategy until symptom control or remission is achieved...
February 14, 2019: British Journal of Nursing: BJN
Doanh Le Huu, Thao Ngo Minh, Thuong Nguyen Van, Phuong Pham Thi Minh, Nghi Dinh Huu, Van Tran Cam, My Le Huyen, Minh Vu Nguyet, Mai Le Thi, Hien Do Thi Thu, Khang Tran Hau, Marco Gandolfi, Francesca Satolli, Claudio Feliciani, Michael Tirant, Aleksandra Vojvodic, Torello Lotti
AIM: This prospective clinical study presents the experiences with NB-UVB monotherapy in the treatment of PLC on Vietnamese patients. METHODS: We enrolled at National Hospital of Dermatology and Venereology (NHDV), Vietnam, 29 PLC patients with generalised disease involving at least 60% of the total body surface (based on Nine's Rule) and/or failed to respond to other modalities of treatment. Patients were treated with NB-UVB followed the guideline of the psoriatic treatment of AAD-2010, three times weekly...
January 30, 2019: Open Access Macedonian Journal of Medical Sciences
Howa Yeung, Kevin M Luk, Suephy C Chen, Brian A Ginsberg, Kenneth A Katz
Lesbian, gay, bisexual, and transgender (LGBT) persons face important health issues relevant to dermatologists. Men who have sex with men (MSM) are at higher risk of certain infectious diseases, including HIV, syphilis and other sexually transmitted diseases (STDs), methicillin-resistant Staphylococcus aureus infections, and invasive meningococcal disease, and might be at higher risk of non-infectious conditions, including skin cancer. Recommendations for preventive health care, including screening for HIV and other STDs, sexual health-related vaccinations, and HIV pre-exposure prophylaxis, differ for MSM compared with non-MSM...
March 2019: Journal of the American Academy of Dermatology
Uday N Shivaji, Caroline L Sharratt, Tom Thomas, Samuel C L Smith, Marietta Iacucci, Gordon W Moran, Subrata Ghosh, Neeraj Bhala
BACKGROUND: Biological therapy is currently widely used to treat IBD. Infliximab, adalimumab and golimumab are currently licensed anti-TNF therapies. Biosimilar anti-TNF monoclonal antibodies are increasingly used. Anti-TNF therapies are widely used and their adverse effects are well characterised, and may cause significant morbidity and mortality in a small proportion of exposed patients. Gastroenterologists need to understand the mechanisms for these effects, recognise these swiftly and manage such events appropriately...
February 8, 2019: Alimentary Pharmacology & Therapeutics
Kim A Papp, Boulos Haraoui, Deepali Kumar, John K Marshall, Robert Bissonnette, Alain Bitton, Brian Bressler, Melinda Gooderham, Vincent Ho, Shahin Jamal, Janet E Pope, A Hillary Steinhart, Donald C Vinh, John Wade
The use of immunosuppressive therapies for immune-mediated disease is associated with an elevated risk of infections and related comorbidities. While many infectious diseases can generally be prevented by vaccines, immunization rates in this specific patient population remain suboptimal, due in part to uncertainty about their efficacy or safety under these clinical situations. To address this concern, a multidisciplinary group of Canadian physicians with expertise in dermatology, gastroenterology, infectious diseases, and rheumatology developed evidence-based clinical guidelines on vaccinations featuring 13 statements that are aimed at reducing the risk of preventable infections in individuals exposed to immunosuppressive and immunomodulatory agents...
February 1, 2019: Journal of Rheumatology
J Berth-Jones, L S Exton, E Ladoyanni, M F Mohd Mustapa, V Tebbs, P D Yesudian, N J Levell
The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the safe and effective use of oral ciclosporin in the field of dermatology. The document aims to: offer an appraisal of all relevant literature since 1970 focusing on any key developments address important, practical clinical questions relating to the primary guideline objective provide guideline recommendations and, where appropriate, with some health economic implications discuss potential developments and future directions The guideline is presented as a detailed review with highlighted recommendations for practical use in the clinic (see section 14), in addition to an updated Patient Information Leaflet (PIL; available on the BAD website, www...
January 17, 2019: British Journal of Dermatology
E C Noels, L M Hollestein, S van Egmond, M Lugtenberg, L P J van Nistelrooij, P Bindels, J van der Lei, R S Stern, T Nijsten, M Wakkee
BACKGROUND: The high prevalence of actinic keratosis (AK) requires optimal use of healthcare resources. OBJECTIVES: To gain insight in health care utilization and management of AK, by describing the healthcare utilization of people with AK in a population-based cohort and in a primary and secondary care setting. METHODS: A retrospective cohort study using three complementary data sources was conducted to describe the use of care, diagnosis, treatment, and follow-up of AK patients in the Netherlands...
January 12, 2019: British Journal of Dermatology
Tomasz Iwanowski, Piotr Szlązak, Alicja Rustowska, Małgorzata Sokołowska-Wojdyło
Introduction: There are many surgical methods for vitiligo treatment that have been used for over 30 years. Suction blister epidermal grafting (SBEG) is considered one of the simplest and most effective of them. Aim: To determine how effective suction blister grafts with concomitant phototherapy are in vitiligo treatment. Material and methods: The study was conducted on 10 patients with vitiligo that was resistant to previous treatment including phototherapy in monotherapy...
December 2018: Postȩpy Dermatologii i Alergologii
Georgi Tchernev, Ivanka Temelkova
BACKGROUND: The American Joint Committee on Cancer (AJCC) offers a two-stage, often insufficient or so-called variable model of cutaneous melanoma treatment. This model starts with primary excision and an initial operational safety margin of 0.5 cm in all directions, followed by a re-excision with an additional field of operational security, determined by histologically established tumor thickness (with or without removal of SLN). We present a brand new method of melanoma surgery, the so-called One Step melanoma surgery (OSMS), in which cutaneous melanomas (regardless of their thickness) could be removed by single surgical intervention...
December 20, 2018: Open Access Macedonian Journal of Medical Sciences
Kevin Lam, Eric A Coomes, Mélissa Nantel-Battista, Jessica Kitchen, An-Wen Chan
Guidelines recommend annual dermatology screening after solid organ transplantation to facilitate early detection of keratinocyte carcinoma (non-melanoma skin cancer), the most common post-transplant malignancy. There are limited data on adherence levels and barriers to screening. We conducted a cross-sectional survey of 477 physicians and nurses providing post-transplant care in Canada. The questionnaire asked about skin cancer screening and education practices, including the perceived importance and barriers...
January 2, 2019: American Journal of Transplantation
Jian Li, Ming Wang, Bo Zhang, Xin Wu, Tian-Long Lin, Xiu-Feng Liu, Ye Zhou, Xin-Hua Zhang, Hao Xu, Li-Jing Shen, Jing Zou, Ping Lu, Dong Zhang, Wei-Jun Gu, Mei-Xia Zhang, Jian Pan, Hui Cao
Tyrosine kinase inhibitors (TKIs) have improved the overall survival of patients with gastrointestinal stromal tumors (GISTs), but their side effects can impact dose intensity and, consequently, the clinical benefit. To date, no guideline or consensus has been published on the TKI-associated adverse reactions. Therefore, the Chinese Society of Surgeons for Gastrointestinal Stromal Tumor of the Chinese Medical Doctor Association organized an expert panel discussion involving representatives from gastrointestinal surgery, medical oncology, cardiology, dermatology, nephrology, endocrinology, and ophthalmology to consider the systemic clinical symptoms, molecular and cellular mechanisms, and treatment recommendations of GISTs...
December 14, 2018: World Journal of Gastroenterology: WJG
Anil Arora, Anil C Anand, Ashish Kumar, Shivaram P Singh, Rakesh Aggarwal, Radha K Dhiman, Shyam Aggarwal, Seema Alam, Pradeep Bhaumik, Vinod K Dixit, Ashish Goel, Bhabadev Goswami, Ashok Kumar, Manoj Kumar, Kaushal Madan, Natarajan Murugan, Aabha Nagral, Amarender S Puri, Padaki N Rao, Neeraj Saraf, Vivek A Saraswat, Sanjeev Sehgal, Praveen Sharma, Koticherry T Shenoy, Manav Wadhawan
Hepatitis B Virus (HBV) reactivation in patients receiving chemotherapy, biologicals, immunosupressants, or corticosteroids is emerging to be an important cause of morbidity and mortality in patients with current or prior exposure to HBV infection. These patients suffer a dual onslaught of illness: one from the primary disease for which they are receiving the culprit drug that led to HBV reactivation, and the other from HBV reactivation itself. The HBV reactivation not only leads to a compromised liver function, which may culminate into hepatic failure; it also adversely impacts the treatment outcome of the primary illness...
December 2018: Journal of Clinical and Experimental Hepatology
F Yang, Y S Zhou, Y Jia
Acquired hemophilia A (AHA) is anunusual disease resulting from autoantibodies (inhibitors) against coagulation factor VIII (FVIII) and clinically manifests as bleeding, which sometimes can cause potentially limb-threatening or life-threatening situations. AHA is associated with cancers, auto-immune disorders, infections, dermatologic conditions and certain medications, among which it is commonly secondary to multiple rheumatologic conditions, such as rheumatoid arthritis, systemic lupus erythematosus (SLE), pollymyositis, autoimmune hemolytic anemia and undifferentiated connective tissue disease...
December 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Christoph Rinner, Emmanuel Helm, Reinhold Dunkl, Harald Kittler, Stefanie Rinderle-Ma
BACKGROUND: Process mining is a relatively new discipline that helps to discover and analyze actual process executions based on log data. In this paper we apply conformance checking techniques to the process of surveillance of melanoma patients. This process consists of recurring events with time constraints between the events. OBJECTIVES: The goal of this work is to show how existing clinical data collected during melanoma surveillance can be prepared and pre-processed to be reused for process mining...
December 10, 2018: International Journal of Environmental Research and Public Health
Jeena K Sandhu, Kevin K Wu, Thanh-Lan Bui, April W Armstrong
Importance: Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with numerous psychiatric comorbidities. However, the association between AD and suicidality has not been well established. Objective: To synthesize the available literature to evaluate the association between AD and suicidality. Data Source: The protocol was prospectively registered in the PROSPERO database (CRD42018105291). Study Selection: Per PRISMA guidelines, PubMed, Embase, PsycINFO, and Cochrane databases were systematically searched for relevant articles published from 1946 to May 25, 2018...
December 12, 2018: JAMA Dermatology
B Llombart, C Serra, C Requena, M Alsina, D Morgado-Carrasco, V Través, O Sanmartín
Sarcomas comprise a broad group of tumors, many of whose biological behavior and aggressiveness differ from one type to another. The therapeutic approach is generally multidisciplinary and often complex. Developments in surgical and oncological dermatology during the last few decades have positioned dermatologists as specialists in the diagnosis and treatment of skin cancer. The aim of this article is to review the main soft tissue sarcomas that typically affect the skin. Dermatofibrosarcoma protuberans is a low-grade malignant sarcoma...
December 2018: Actas Dermo-sifiliográficas
C Eldin, A Raffetin, K Bouiller, Y Hansmann, F Roblot, D Raoult, P Parola
Lyme disease is a tick-borne bacterial disease with polymorphic clinical manifestations (cutaneous, rheumatological, and neurological). In recent years the issue of the diagnosis of this infection has been highly publicized on the Internet and other media in Europe and America. Some patients and physicians may share the perception that the diagnosis of the infection is not reliable in France. We reviewed current European and American guidelines on Lyme disease and performed a methodological evaluation of all guidelines...
December 6, 2018: Médecine et Maladies Infectieuses
Li Hou, Hongyu Kang, Yan Liu, Luqi Li, Jiao Li
BACKGROUND: Health professionals and consumers use different terms to express medical events or concerns, which makes the communication barriers between the professionals and consumers. This may lead to bias in the diagnosis or treatment due to the misunderstanding or incomplete understanding. To solve the issue, a consumer health vocabulary was developed to map the consumer-used health terms to professional-used medical terms. METHODS: In this study, we extracted Chinese consumer health terms from both online health forum and patient education monographs, and manually mapped them to medical terms used by professionals (terms in medical thesauri or in medical books)...
December 7, 2018: BMC Medical Informatics and Decision Making
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