keyword
https://read.qxmd.com/read/38506985/participant-evaluation-of-a-multi-disciplinary-oncology-preceptorship-training-program-for-oncology-health-professionals-from-kumasi-ghana
#1
JOURNAL ARTICLE
Kenneth W Merrell, Thomas Okpoti Konney, Osei Acheamfour, Joseph Lucido, Abena Yeboah Aduse-Poku, Amanika Kumar, Mavis Bobie Ansah, Adu Tutu Amankwa, Dean Shumway, Fred Kwame Awittor, Augustina Badu-Peprah, Lionel Aurelien A Kankeu Fonkoua, Andrea E Wahner Hendrickson, Ernest Boakye, Ernest Kwasi Adjei, Ishmael Kyei, Katie Kemper, Miranda Rank, Prema P Peethambaram, Kathryn Spangenberg, Kasie Sorenson, Miranda Hearrold, Allison Garda, Rondell Graham, Karen Lang, Joseph Adom, Rita Achiaa, James Jakub, Bismark Dwobeng Amo, Ernest Osei-Bonsu, Rolando Camacho, Eric Clement Desmond Kotei Addison
A critical shortage of skilled healthcare workers is a primary cause of disparate global cancer outcomes. We report participant evaluation of a multidisciplinary preceptorship program. In collaboration with the city of Kumasi, Ghana, Mayo Clinic and the City Cancer Challenge hosted a preceptorship program for comprehensive multidisciplinary breast and cervix cancer training. A total of 14 healthcare workers from Kumasi received two weeks of training at Mayo Clinic in November and December 2021. Each participant and preceptor were requested to complete an anonymous post-participation survey...
March 20, 2024: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://read.qxmd.com/read/38468817/lifestyle-factors-and-cancer-a-narrative-review
#2
JOURNAL ARTICLE
Reya Sharman, Zoey Harris, Brenda Ernst, Dawn Mussallem, Ashley Larsen, Krisstina Gowin
Lifestyle factors and their impact on cancer prevention, prognosis, and survivorship are increasingly recognized in the medical literature. Lifestyle factors are primarily defined here as diet and physical activity. We conducted a narrative review of the primary published data, including randomized controlled trials and prospective studies, on the impact of primary lifestyle factors on oncogenesis and clinical outcomes in the preventative and survivorship setting. First, we discuss the oncogenic mechanisms behind primary lifestyle factors (diet, physical activity and, within these 2, obesity)...
April 2024: Mayo Clinic Proceedings. Innovations, Quality & Outcomes
https://read.qxmd.com/read/38462235/the-screening-diagnosis-and-management-of-patients-with-autosomal-dominant-polycystic-kidney-disease-a-national-consensus-statement-from-taiwan
#3
REVIEW
Pao-Wen Yen, Yung-An Chen, Wei Wang, Fang-Sheng Mao, Chia-Ter Chao, Chih-Kang Chiang, Shih-Hua Lin, Der-Cherng Tarng, Yi-Wen Chiu, Ming-Ju Wu, Yung-Chang Chen, Juliana Tze-Wah Kao, Mai-Szu Wu, Chun-Liang Lin, Jenq-Wen Huang, Kuan-Yu Hung
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of end-stage kidney disease (ESKD) worldwide. Guidelines for the diagnosis and management of ADPKD in Taiwan remains unavailable. In this consensus statement, we summarize updated information on clinical features of international and domestic patients with ADPKD, followed by suggestions for optimal diagnosis and care in Taiwan. Specifically, counselling for at-risk minors and reproductive issues can be important, including ethical dilemmas surrounding prenatal diagnosis and pre-implantation genetic diagnosis...
March 10, 2024: Nephrology
https://read.qxmd.com/read/38461879/follow-up-and-outcomes-of-186-patients-with-follicular-cell-derived-thyroid-cancer-seen-at-a-referral-center-by-one-thyroidologist-in-2015
#4
JOURNAL ARTICLE
Vahab Fatourechi
OBJECTIVE: To study the profile, management, and outcomes of follicular cell-derived thyroid cancer (FCDTC) before publication of the 2016 American Thyroid Association guidelines recommending less aggressive thyroid cancer procedures. METHODS: Patients with FCDTC were seen by one thyroidologist at Mayo Clinic during the 2015 calendar year. Patients underwent surgical procedures for FCDTC in 2015 or earlier at the Mayo Clinic or another institution. Follow-up data were collected from January 1, 2016, through July 20, 2022...
March 8, 2024: Endocrine Practice
https://read.qxmd.com/read/38456874/emulated-trial-for-discharge-prescription-of-guideline-directed-medical-therapy-and-15-year-survival-after-coronary-artery-bypass-graft-surgery
#5
JOURNAL ARTICLE
Yaron Moshkovitz, Liat Orenstein, Liraz Olmer, Keren Laufer, Arnona Ziv, Rachel Dankner
OBJECTIVES: To explore admission and discharge prescription rates of guideline-directed medical therapy (GDMT), defined as aggregate antiplatelet agents, statins, and β-blockers, after coronary artery bypass graft (CABG) surgery and to reveal its association with long-term survival. PATIENTS AND METHODS: This is a prospective cohort study-based emulated trial of patients undergoing elective or semi-elective isolated CABG surgery in 7 cardiothoracic units in Israel from January 1, 2004, to December 31, 2007, and followed up until December 31, 2020, for all-cause mortality...
March 6, 2024: Mayo Clinic Proceedings
https://read.qxmd.com/read/38403180/update-in-outpatient-general-internal-medicine-practice-changing-evidence-published-in-2023
#6
REVIEW
Majken T Wingo, Carl A Andersen, Shari L Bornstein, Jill M Huber, Jason H Szostek, Mark L Wieland
The expansive scope of internal medicine can make it challenging for clinicians to stay informed about new literature that changes practice. Guideline updates and synthesis of relevant evidence can facilitate incorporation of advancements into clinical practice. The titles and abstracts from the seven general medicine journals with highest impact factors and relevance to outpatient internal medicine were reviewed by six internal medicine physicians. Coronavirus disease 19 research was excluded. The New England Journal of Medicine (NEJM), The Lancet, Journal of the American Medical Association (JAMA), The British Medical Journal (BMJ), Annals of Internal Medicine, JAMA Internal Medicine, and Mayo Clinic Proceedings were reviewed...
February 23, 2024: American Journal of Medicine
https://read.qxmd.com/read/38365699/treatment-strategies-for-simple-elbow-dislocation%C3%A2-a-systematic-review
#7
JOURNAL ARTICLE
Franziska Lioba Breulmann, Sebastian Lappen, Yannick Ehmann, Martin Bischofreiter, Lucca Lacheta, Sebastian Siebenlist
BACKGROUND: Current treatment concepts for simple elbow dislocation involve conservative and surgical approaches. The aim of this systematic review was to identify the superiority of one treatment strategy over the other by a qualitative analysis in adult patients who suffered simple elbow luxation. STUDY DESIGN: A systematic review in accordance with the PRISMA guidelines and following the suggestions for reporting on qualitative summaries was performed. A literature search was conducted using PubMed and Scopus, including variations and combinations of the following keywords: elbow, radiohumeral, ulnohumeral, radioulnar, luxation, and therapy...
February 16, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38357713/platelet-rich-plasma-has-better-results-for-long-term-functional-improvement-and-pain-relief-for-lateral-epicondylitis-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#8
JOURNAL ARTICLE
Yang Xu, Tao Li, Li Wang, Lei Yao, Jian Li, Xin Tang
BACKGROUND: Corticosteroids (CS) have shown good short-term performance in terms of pain relief and functional improvement. However, the safety and long-term efficacy of this treatment remains controversial. Several studies have reported good results of platelet-rich plasma (PRP) in the treatment of tendinopathies. However, whether its use in the treatment of lateral epicondylitis (LE) is superior to that of CS remains controversial. PURPOSE: To perform a systematic review and meta-analysis of original studies to determine whether the prognosis of LE patients treated with PRP is better than that of CS...
February 15, 2024: American Journal of Sports Medicine
https://read.qxmd.com/read/38329526/is-generative-pre-trained-transformer-artificial-intelligence-chat-gpt-a-reliable-tool-for-guidelines-synthesis-a-preliminary-evaluation-for-biologic-crswnp-therapy
#9
JOURNAL ARTICLE
Antonino Maniaci, Alberto Maria Saibene, Christian Calvo-Henriquez, Luigi Vaira, Thomas Radulesco, Justin Michel, Carlos Chiesa-Estomba, Leigh Sowerby, David Lobo Duro, Miguel Mayo-Yanez, Juan Maza-Solano, Jerome Rene Lechien, Ignazio La Mantia, Salvatore Cocuzza
INTRODUCTION: Biologic therapies for Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) have emerged as an auspicious treatment alternative. However, the ideal patient population, dosage, and treatment duration are yet to be well-defined. Moreover, biologic therapy has disadvantages, such as high costs and limited access. The proposal of a novel Artificial Intelligence (AI) algorithm offers an intriguing solution for optimizing decision-making protocols. METHODS: The AI algorithm was initially programmed to conduct a systematic literature review searching for the current primary guidelines on biologics' clinical efficacy and safety in treating CRSwNP...
February 8, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38283097/show-me-ckdintercept-initiative-a-collective-impact-approach-to-improve-population-health-in-missouri
#10
JOURNAL ARTICLE
Katelyn Laue, Megan Schultz, Elizabeth Talbot-Montgomery, Alexandra Garrick, Anuja Java, Christine Corbett, Dana M Lammert, JoAnna Rogers, Kathleen Davis, Kunal Malhotra, Marie Philipneri, Mary Ann Kimbel, Reem A Mustafa, Valerie Hardesty
Ninety percent of people with chronic kidney disease (CKD) remain undiagnosed, most people at risk do not receive guideline-concordant testing, and disparities of care and outcomes exist across all stages of the disease. To improve CKD diagnosis and management across primary care, the National Kidney Foundation launched a collective impact (CI) initiative known as Show Me CKDintercept. The initiative was implemented in Missouri, USA from January 2021 to June 2022, using a data strategy, stakeholder engagement and relationship mapping, learning in action working groups (LAWG), and a virtual leadership summit...
February 2024: Mayo Clinic Proceedings. Innovations, Quality & Outcomes
https://read.qxmd.com/read/38276943/advances-in-screening-for-barrett-esophagus-and-esophageal-adenocarcinoma
#11
REVIEW
Kornpong Vantanasiri, Amrit K Kamboj, John B Kisiel, Prasad G Iyer
Esophageal adenocarcinoma (EAC), the primary form of esophageal cancer in the United States, is a lethal cancer with exponentially increasing incidence. Screening for Barrett esophagus (BE), the only known precursor to EAC, followed by endoscopic surveillance to detect dysplasia and early-stage EAC and subsequent endoscopic treatment (to prevent progression of dysplasia to EAC and to treat early-stage EAC effectively) is recommended by several society guidelines. Sedated endoscopy (the primary current tool for BE screening) is both invasive and expensive, limiting its widespread use...
March 2024: Mayo Clinic Proceedings
https://read.qxmd.com/read/38259804/physical-restraint-usage-in-hospitals-across-the-united-states-2011-2019
#12
JOURNAL ARTICLE
Ishaan Gupta, Ilana Nelson-Greenberg, Scott Mitchell Wright, Ché Matthew Harris
OBJECTIVE: To determine the change in rates of physical restraint (PR) use and associated outcomes among hospitalized adults. PATIENTS AND METHODS: Using national inpatient sample databases, we analyzed years 2011-2014 and 2016-2019 to determine trends of PR usage. We also compared the years 2011-2012 and 2018-2019 to investigate rates of PR use, in-hospital mortality, length of stay, and total hospital charges. RESULTS: There were 242,994,110 hospitalizations during the study period...
February 2024: Mayo Clinic Proceedings. Innovations, Quality & Outcomes
https://read.qxmd.com/read/38244097/practical-management-of-hypertrophic-scarring-the-mayo-clinic-experience
#13
JOURNAL ARTICLE
Julia Tomtschik, Nimay Anand, Samyd S Bustos, Jorys Martinez-Jorge, Saranya P Wyles
Hypertrophic scarring is a potential consequence of wound healing that causes functional and aesthetic disability. Common treatments include intralesional pharmacotherapy (e.g., triamcinolone), surgical excision, and energy-based laser devices. While numerous treatment methods have been described for hypertrophic scarring, an optimal treatment strategy has yet to be established given variability in clinical presentation. This study aims to identify patient- and provider-preferred treatment patterns. This is a single-center, retrospective study of adult patients that developed post-surgical hypertrophic scarring between 2007 and 2017...
January 20, 2024: Archives of Dermatological Research
https://read.qxmd.com/read/38243666/development-and-evaluation-of-best-practice-advisory-alert-for-patient-eligibility-in-a-hospital-at-home-program-a-multicenter-retrospective-study
#14
JOURNAL ARTICLE
Michael J Maniaci, Ricardo A Torres-Guzman, Francisco R Avila, Karla Maita, John P Garcia, Antonio J Forte, Rachel Rutledge, Sagar B Dugani, Shannon M Campbell, Ingrid J Pritchard, Margaret R Paulson
BACKGROUND: Hospital-at-home (HaH) is a growing model of care that has been shown to improve patient outcomes, satisfaction, and cost-effectiveness. However, selecting appropriate patients for HaH is challenging, often requiring burdensome manual screening by clinicians. To facilitate HaH enrollment, electronic health record (EHR) tools such as best practice advisories (BPAs) can be used to alert providers of potential HaH candidates. OBJECTIVE: To describe the development and implementation of a BPA for identifying HaH eligible patients in Mayo Clinic's Advanced Care at Home (ACH) program, and to evaluate the provider response and the patient characteristics that triggered the BPA...
January 19, 2024: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://read.qxmd.com/read/38157995/an-analysis-of-the-recommendations-of-the-2022-society-for-vascular-surgery-clinical-practice-guidelines-for-patients-with-asymptomatic-carotid-stenosis
#15
JOURNAL ARTICLE
Ali AbuRahma
OBJECTIVE: Patients with asymptomatic carotid artery stenosis currently account for the majority of carotid interventions performed in the United States; therefore, the following article will review the 2022 Society for Vascular Surgery (SVS) clinical practice guidelines perspective in treating patient with asymptomatic carotid stenosis. METHODS: A systemic review and meta-analysis were conducted by the evidence practice center of the Mayo Clinic using a specified population, intervention, comparison, outcome (PICO) framework...
December 27, 2023: Journal of Vascular Surgery
https://read.qxmd.com/read/38129602/patient-perceptions-of-altering-chemotherapy-treatment-due-to-peripheral-neuropathy
#16
JOURNAL ARTICLE
Daniel L Hertz, Cindy Tofthagen, Emanuela Rossi, Davide Paolo Bernasconi, Jiyoon Lim, Martha Carlson, Katharine E Sheffield, Larissa Nekhlyudov, Lisa Grech, Diane Von Ah, Samantha J Mayo, Kathryn J Ruddy, Alexandre Chan, Paola Alberti, Maryam B Lustberg, Mary Tanay
PURPOSE: Clinical practice guidelines recommend altering neurotoxic chemotherapy treatment in patients experiencing intolerable chemotherapy-induced peripheral neuropathy (CIPN). The primary objective of this survey was to understand patient's perspectives on altering neurotoxic chemotherapy treatment, including their perceptions of the benefits of preventing irreversible CIPN and the risks of reducing treatment efficacy. METHODS: A cross-sectional online survey was distributed via social networks to patients who were currently receiving or had previously received neurotoxic chemotherapy for cancer...
December 22, 2023: Supportive Care in Cancer
https://read.qxmd.com/read/38066214/assessment-of-interobserver-concordance-in-radiomic-tools-for-lung-nodule-classification-with-a-focus-on-broders-and-sila
#17
JOURNAL ARTICLE
Faysal Al-Ghoula, Khushbu Patel, Sam Falde, Srinivasan Rajagopalan, Brian Bartholmai, Fabien Maldonado, Tobias Peikert
While CT lung cancer screening reduces lung cancer-specific mortality, there are remaining challenges. Radiomic tools promiss to address these challenges, however, they are subject to interobserver variability if semi-automated segmentation techniques are used. Herein we report interobserver variability for two validated radiomic tools, BRODERS (Benign versus aggRessive nODule Evaluation using Radiomic Stratification) and CANARY (Computer-Aided Nodule Assessment and Risk Yield). We retrospectively analyzed the CT images of 95 malignant lung nodules of the adenocarcinoma spectrum using BRODERS and CANARY...
December 8, 2023: Scientific Reports
https://read.qxmd.com/read/38036253/postoperative-mobilization-after-terrible-triad-injury-systematic-review-and-single-arm-meta-analysis
#18
REVIEW
Sherif Ahmed Kamel, Jenna Shepherd, Awf Al-Shahwani, Eslam Abourisha, Divine Maduka, Harvinder Singh
BACKGROUND: Terrible triad is a complex injury of the elbow, involving elbow dislocation with associated fracture of the radial head, avulsion or tear of the lateral ulnar collateral ligament and fracture of the coronoid. These injuries are commonly managed surgically with fixation or replacement of the radial head, repair of collateral ligaments, with or without fixation of the coronoid. Postoperative mobilization is a significant factor that may affect patient outcomes; however the optimal postoperative mobilization protocol is unclear...
November 28, 2023: Journal of Shoulder and Elbow Surgery
https://read.qxmd.com/read/38000064/survival-outcomes-of-intracranial-extraventricular-neurocytomas-a-systematic-review-and-individual-patient-data-meta-analysis
#19
JOURNAL ARTICLE
Barry Ting Sheen Kweh, Mina Asaid, Boyuan Khoo, Christopher Donaldson, Julie Lokan, Hui K Gan, Augusto Carlos Gonzalvo
OBJECTIVE: The rarity of intracranial extraventricular neurocytomas (EVNs) has precluded accurate definition of its surgical characteristics to date. The authors present the first survival analysis of this unique entity that aims to clarify tumor characteristics, surgical outcomes, and efficacy of postoperative adjuvant therapy. METHODS: A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
November 24, 2023: Journal of Neurosurgery
https://read.qxmd.com/read/37962562/the-vus-challenge-in-cystic-kidney-disease-a-case-based-review
#20
JOURNAL ARTICLE
Abinet M Aklilu, Ashima Gulati, Kayla J Kolbert, Hana Yang, Peter C Harris, Neera K Dahl
Genetic testing in nephrology is becoming increasingly important to diagnose patients and to provide appropriate care. This is especially true for Autosomal Dominant Polycystic Kidney Disease (ADPKD) because this is a common cause of kidney failure and genetically complex. As well as the major genes, PKD1 and PKD2, there are at least 6 minor loci, and phenotypic, and in some cases, genetic overlap with other cystic disorders. Targeted Next Generation Sequencing (tNGS), a low cost, high throughput technique, has made routine genetic testing viable in nephrology clinics...
November 14, 2023: Kidney360
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