Liuyan Kuang, Yanting You, Jieying Qi, Jieyu Chen, Xinghong Zhou, Shuai Ji, Jingru Cheng, Hiu Yee Kwan, Pingping Jiang, Xiaomin Sun, Mengting Su, Ming Wang, Wenxiao Chen, Ren Luo, Xiaoshan Zhao, Lin Zhou
CONTEXT: Qi-dan-dihuang decoction (QDD) has been used to treat diabetic kidney disease (DKD), but the underlying mechanisms are poorly understood. OBJECTIVE: This study reveals the mechanism by which QDD ameliorates DKD. MATERIALS AND METHODS: The compounds in QDD were identified by high-performance liquid chromatography and quadrupole-time-of-flight tandem mass spectrometry (HPLC-Q-TOF-MS). Key targets and signaling pathways were screened through bioinformatics...
March 8, 2024: Environmental Toxicology