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JOURNAL ARTICLE
Amr T El Hawary, Fedaa Nabil, Ramy El Hendawy, Haytham K A Mahrous, Ghada A AbdelHamid, Mahmoud Amer
Hepatocellular carcinoma (HCC) is one of the most prevalent cancers in the world. Two risk factors that cause 80-90% of HCC cases globally are chronic infection with hepatitis B virus (HBV) and hepatitis C virus (HCV). The diagnostic value of circulating microRNAs (miRNAs) in numerous tumors has been described. Our research assessed microRNA-16 (miR-16) as a novel biomarker in patients with HCV-induced HCC. The study included three groups. Group 1 included 55 individuals with cirrhosis caused by liver HCV infection in addition to HCC...
April 2024: Egyptian Journal of Immunology
#22
JOURNAL ARTICLE
Samir Al Bashir, Majd M AlBarakat, Karam K Alabedalhalim, Ali Al-Khalaileh, Amer Alassaf, Othman Saleh, Asmaa W Ayyad, Karem H Alzoubi
The delayed presentation of cancer patients to healthcare facilities for diagnosis is a pressing issue, as late-stage cancer cases are often more challenging to treat effectively. In low-resource settings, such as those with limited access to healthcare facilities, the impact of inadequate awareness of cancer signs and symptoms can be particularly severe. Therefore, this study aimed to evaluate public knowledge of cancer signs and symptoms and risk factors in the context of Jordan. This cross-sectional study was conducted among participants from all settings...
April 12, 2024: Medicine (Baltimore)
#23
JOURNAL ARTICLE
Chun Wang, Khushpreet Kaur, Canxin Xu, Yousef Abu-Amer, Gabriel Mbalaviele
Chemotherapy is a widely used treatment for a variety of solid and hematological malignancies. Despite its success in improving the survival rate of cancer patients, chemotherapy causes significant toxicity to multiple organs, including the skeleton, but the underlying mechanisms have yet to be elucidated. Using tumor-free mouse models, which are commonly used to assess direct off-target effects of anti-neoplastic therapies, we found that doxorubicin caused massive bone loss in wild-type mice, a phenotype associated with increased number of osteoclasts, leukopenia, elevated serum levels of danger-associated molecular patterns (DAMPs; e...
April 11, 2024: ELife
#24
JOURNAL ARTICLE
Wael A Khalil, Mahmoud A E Hassan, Sally Ibrahim, Amer K Mohammed, Mostafa A El-Harairy, Sameh A Abdelnour
Although cryopreservation is a reliable method used in assisted reproduction to preserve genetic materials, it can stimulate the occurrence of oxidative stress, which affects sperm structure and function. This research was conducted to explore the effects of quinoa seed extracts (QSE) on ram sperm quality, oxidative biomarkers, and the gene expression of frozen-thawed ram sperm. Semen samples were diluted in extenders supplemented with 0 (QSE0), 250 (QSE1), 500 (QSE2), 750 (QSE3), and 1000 (QSE4) µg of QSE /mL, and then frozen according to the typical procedure...
April 4, 2024: Animal Reproduction Science
#25
JOURNAL ARTICLE
Mohammad Daher, Gaby Haykal, Marven Aoun, Marc Moussallem, Ali Ghoul, Jean Tarchichi, Amer Sebaaly
BACKGROUND: Knee and hip osteoarthritis affects millions of people around the world and is expected to rise even more in frequency as the population ages. Joint arthroplasty is the surgical management of choice in these articulations. Heterotopic ossification and radiolucent lines formation are two frequent problems faced in hip and knee replacements respectively. Some studies show that the usage of pulsed lavage may prevent their formation. AIM: To compare pulsed lavage to standard lavage in joint arthroplasty...
March 18, 2024: World Journal of Orthopedics
#26
Marwah K Almalki, Alauldin K Alhowaish, Amer A Alharbi, Abdullah M Alsehli, Amin K Makhdoom
Lymphangioma circumscriptum (LC) is an uncommon malformation affecting the skin and subcutaneous tissue. This report documents a case of LC that developed in the scrotum of a 35-year-old male. Upon examination, numerous clusters of clear vesicles were found on the scrotum's surface. The patient had no previous exposure to infections, trauma, surgery, or radiation treatment. A skin biopsy revealed enlarged lymphatic channels in the dermis, aligning with a diagnosis of LC. The patient was treated with cryotherapy using liquid nitrogen, specifically targeting the translucent yellowish vesicles...
March 2024: Curēus
#27
JOURNAL ARTICLE
Ahmed Ali El-Shemy, Mohamed Mahrous Amer, Heba M Hassan, Mohamed Elaish
BACKGROUND AND AIM: Respiratory viral infections significantly negatively impact animal welfare and have significant financial implications in the poultry industry. This study aimed to determine the frequency of the most economically relevant respiratory viruses that circulated in Egyptian chicken flocks in 2022. MATERIALS AND METHODS: Chickens from 359 broiler flocks in five different Egyptian governorates in the Nile Delta (Beheira, Gharbia, Giza, Monufiya, and Qalyoubia) at marketing time (33-38 days of age) were used in this study...
February 2024: Veterinary World
#28
JOURNAL ARTICLE
Kiran S Shankar, Meighana Arumugham, Minhaj Ahmed Amer Mohammed, Sunpreet Kaur Sandhu, Darshana Bennadi, Jeetu Verma, Saraswathi Sravani Pulluri
To assess how oral health education (OHE) techniques using braille affect visually impaired children's awareness of oral health, oral hygiene status and practices, plaque, gingival health, and dental caries status. From 2010 to 2020, a thorough literature search will be conducted for studies in the English language using PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, Google Scholar, and Open Grey. Data extraction will be done after two reviewers extensively evaluate the papers for qualifying requirements...
February 2024: Journal of Pharmacy & Bioallied Sciences
#29
JOURNAL ARTICLE
Tanu Singh, Saurav Bathla, Saurav Kumar Dutta, Minhaj Ahmed Amer Mohammed, Navdeep Jethi, Harsh Chansoria, Saraswathi Sravani Pulluri
INTRODUCTION: In-depth knowledge of common and aberrant pulp morphology is essential for appropriate diagnosis and treatment planning before commencing root canal treatment. The radicular morphology of mandibular molars has been extensively studied. Considerable variation in the number of canals and roots found in these teeth has been reported. AIM: The purpose of this study is to investigate the root canal morphology of the mandibular molars among the Rohilkhand population using Dentascan...
February 2024: Journal of Pharmacy & Bioallied Sciences
#30
JOURNAL ARTICLE
Negaur Iranpour, Aatur Singhi, Kevan Jonathan Salimian, Javad R Azadi, Adam Slivka, Ka-Kei Ngan, Kevin McGrath, Kenneth Fasanella, Amer Zureikat, Alessandro Paniccia, Atif Zaheer, Anil K Dasyam
PURPOSE: Pancreatic intraductal oncocytic papillary neoplasms (IOPN) are rare precursors to pancreatic ductal adenocarcinoma. We report cross-sectional computed tomography and magnetic resonance imaging (where available) findings of pancreatic IOPNs. MATERIALS AND METHODS: Consecutive cases of pancreatic IOPNs identified on pathology between 2008 and 2020 at University of Pittsburgh and Johns Hopkins University were included in the study. Cross-sectional imaging of all patients was reviewed by two subspecialty trained abdominal radiologists...
April 9, 2024: Journal of Computer Assisted Tomography
#31
JOURNAL ARTICLE
Heba A Hekal, Maggie E Amer, Maher Amer, Mohamed A El-Missiry, Azza I Othman
Selenium (Se) is an important micronutritional biomolecule in cancer therapy. The current work evaluated the anticancer effect of Se and its ability to improve health of mice with solid Ehrlich carcinoma implanted subcutaneously. Four groups of five female BALB/c mice each were assembled. Ehrlich tumor cells were engrafted into two of them, either with or without Se therapy. The other groups served as control groups, either with or without Se treatment. Se treatment resulted in a notable decrease in both tumor volume and animal body mass in tumor-bearing mice...
April 9, 2024: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
#32
JOURNAL ARTICLE
Lindsey K Jennings, Laura Lander, Tricia Lawdahl, Erin A McClure, Angela Moreland, Jenna L McCauley, Louise Haynes, Timothy Matheson, Richard Jones, Thomas E Robey, Sarah Kawasaki, Phillip Moschella, Amer Raheemullah, Suzette Miller, Gina Gregovich, Deborah Waltman, Kathleen T Brady, Kelly S Barth
INTRODUCTION: Emergency departments (ED) are incorporating Peer Support Specialists (PSSs) to help with patient care for substance use disorders (SUDs). Despite rapid growth in this area, little is published regarding workflow, expectations of the peer role, and core components of the PSS intervention. This study describes these elements in a national sample of ED-based peer support intervention programs. METHODS: A survey was conducted to assess PSS site characteristics as part of site selection process for a National Institute on Drug Abuse (NIDA) Clinical Trials Network (CTN) evaluating PSS effectiveness, Surveys were distributed to clinical sites affiliated with the 16 CTN nodes...
April 8, 2024: Addiction Science & Clinical Practice
#33
Shubash Adhikari, Adam Belcher, Frank Annie, Muhammad Amer
No abstract text is available yet for this article.
February 2024: CJC open
#34
JOURNAL ARTICLE
Luciano Mastronardi, Alberto Campione, Amer Ahmad Alomari
INTRODUCTION: Surgical strategy for meningioma resection in the elderly is controversial: diverse studies in the literature have pointed at the age as a negative prognostic factor in terms of postoperative results. RESEARCH QUESTION: The aim of this study is to compare surgical outcomes after resection of posterior fossa meningiomas in <70 and ≥ 70 years-old age groups. MATERIAL AND METHODS: We reviewed 72 patients affected by posterior fossa meningiomas who underwent surgical treatment at San Filippo Neri Hospital, Rome, Italy between September 2010 and December 2022...
2024: Brain Spine
#35
JOURNAL ARTICLE
Arwa S Amer, Ahmed Y Al Shambaky, Seham G Ameen, Amira Khalil Sobih
BACKGROUND: Enthesopathy is considered a crucial aspect of assessment and outcome in psoriatic arthritis (PsA). Musculoskeletal ultrasound (MSUS) is a critical tool for accurately detecting enthesitis. Recent research focuses on identifying simple biomarkers for detecting and monitoring psoriatic enthesopathy. Red cell distribution width (RDW), mean platelet volume (MPV), and neutrophil/lymphocyte ratio (NLR) are components of a complete blood count (CBC) and are reliable bio-inflammatory markers in various rheumatic diseases...
April 8, 2024: Clinical Rheumatology
#36
JOURNAL ARTICLE
Abeer A Ahmed, Marwa Ghoneim, Mahmoud A A Ali, Alia Amer, Aleksandra Głowacka, Mohamed A A Ahmed
One of the significant aromatic plants applied in food and pharma is cumin. Despite its massive trading in Egypt, there are no comprehensive reports on cumin landraces profile screening. This study aimed to investigate the variation in seeds' physical and biochemical profiles and genetic diversity as well as assess the efficiency of seeds' germination under salinity stress. Consequently, during the 2020/2021 growing season, four common cumin seed landraces were gathered from various agro-climatic regions: El Gharbia, El Menia, Assiut, and Qena...
April 5, 2024: Scientific Reports
#37
JOURNAL ARTICLE
Yazan Madanat, Michael R Savona, Mikkael A Sekeres, Uwe Platzbecker, Valeria Santini, Pierre Fenaux, Maria Diez-Campelo, David Valcárcel, Tymara Berry, Souria Dougherty, Sheetal Shah, Libo Sun, Ying Wan, Fei Huang, Shyamala Navada, Rami S Komrokji, Amer M Zeidan
No abstract text is available yet for this article.
April 5, 2024: Journal of the National Comprehensive Cancer Network: JNCCN
#38
JOURNAL ARTICLE
Paola Castrogiovanni, Cristina Sanfilippo, Rosa Imbesi, Giacomo Lazzarino, Giovanni Li Volti, Daniele Tibullo, Nunzio Vicario, Rosalba Parenti, Lazzarino Giuseppe, Ignazio Barbagallo, Amer M Alanazi, Michele Vecchio, Francesco Cappello, Giuseppe Musumeci, Michelino Di Rosa
Muscle damage resulting from physical activities such as exercise triggers an immune response crucial for tissue repair and recovery. This study investigates the immune cell profiles in muscle biopsies of individuals engaged in resistance exercise (RE) and explores the impact of age and sex on the immune response following exercise-induced muscle damage. Microarray datasets from muscle biopsies of young and old subjects were analyzed, focusing on the gene expression patterns associated with immune cell activation...
April 5, 2024: Journal of Muscle Research and Cell Motility
#39
JOURNAL ARTICLE
John McDonnell, Kimberley Cousins, M Elizabeth M Younger, Adam Lane, Hassan Abolhassani, Roshini S Abraham, Salem Al-Tamemi, Juan Carlos Aldave-Becerra, Eman Hesham Al-Faris, Alberto Alfaro-Murillo, Suzan A AlKhater, Nouf Alsaati, Alexa Michelle Altman Doss, Melissa Anderson, Ernestina Angarola, Barbara Ariue, Danielle E Arnold, Amal H Assa'ad, Caner Aytekin, Meaghan Bank, Jenna R E Bergerson, Jack Bleesing, John Boesing, Carolina Bouso, Nicholas Brodszki, Diana Cabanillas, Carol Cady, Meghan A Callahan, Roberta Caorsi, Javier Carbone, Maria Carrabba, Riccardo Castagnoli, Jason R Catanzaro, Samantha Chan, Sharat Chandra, Hugo Chapdelaine, Zahra Chavoshzadeh, Hey Jin Chong, Lori Connors, Filippo Consonni, Oscar Correa-Jimenez, Charlotte Cunningham-Rundles, Katherine D'Astous-Gauthier, Ottavia Maria Delmonte, Yesim Yilmaz Demirdag, Deepti R Deshpande, Natalie M Diaz-Cabrera, Victoria R Dimitriades, Rasha El-Owaidy, Gehad ElGhazali, Suleiman Al-Hammadi, Giovanna Fabio, Astrid Schellnast Faure, Jin Feng, James M Fernandez, Lauren Fill, Guacira R Franco, Robert W Frenck, Ramsay L Fuleihan, Giuliana Giardino, Jessica Galant-Swafford, Eleonora Gambineri, Elizabeth K Garabedian, Ashley V Geerlinks, Ekaterini Goudouris, Octavio Grecco, Qiang Pan-Hammarström, Hedieh Haji Khodaverdi Khani, Lennart Hammarström, Nicholas L Hartog, Jennifer Heimall, Gabriela Hernandez-Molina, Caroline C Horner, Robert W Hostoffer, Nataliya Hristova, Kuang-Chih Hsiao, Gabriela Ivankovich-Escoto, Faris Jaber, Maaz Jalil, Mahnaz Jamee, Tiffany Jean, Stephanie Jeong, Devi Jhaveri, Michael B Jordan, Avni Y Joshi, Amanpreet Kalkat, Henry J Kanarek, Erinn S Kellner, Amer Khojah, Ruby Khoury, Cristina M Kokron, Ashish Kumar, Kelsey Lecerf, Heather K Lehman, Jennifer W Leiding, Harry Lesmana, Xin Rong Lim, Joao Pedro Lopes, Ana Laura López, Lucia Tarquini, Ingrid S Lundgren, Julieann Magnusson, Ana Karolina B B Marinho, Gian Luigi Marseglia, Giulia M Martone, Annamaria G Mechtler, Leonardo Mendonca, Joshua D Milner, Peter J Mustillo, Asal Gharib Naderi, Samuele Naviglio, Jeremy Nell, Hana B Niebur, Luigi Notarangelo, Matias Oleastro, María Claudia Ortega-López, Neil R Patel, Gordana Petrovic, Claudio Pignata, Oscar Porras, Benjamin T Prince, Jennifer M Puck, Nashmia Qamar, Marco Rabusin, Nikita Raje, Lorena Regairaz, Kimberly A Risma, Elizabeth H Ristagno, John Routes, Persio Roxo-Junior, Negin Salemi, Christopher Scalchunes, Susan J Schuval, Suranjith L Seneviratne, Ashwin Shankar, Roya Sherkat, Junghee Jenny Shin, Abeer Siddiqi, Sara Signa, Ali Sobh, Fabiana Mascarenhas Souza Lima, Kristen K Stenehjem, Jonathan S Tam, Monica Tang, Myrthes Toledo Barros, James Verbsky, Eleni Vergadi, Dayne H Voelker, Stefano Volpi, Luke A Wall, Christine Wang, Kelli W Williams, Eveline Y Wu, Shan Shan Wu, Jessie J Zhou, Alexandria Cook, Kathleen E Sullivan, Rebecca Marsh
BACKGROUND: The CDC and ACIP recommend COVID-19 vaccination for patients with inborn errors of immunity (IEI). Not much is known about vaccine safety in IEI, and whether vaccination attenuates infection severity in IEI. OBJECTIVE: To estimate COVID-19 vaccination safety and examine effect on outcomes in patients with IEI. METHODS: We built a secure registry database in conjunction with the US Immunodeficiency Network to examine vaccination frequency and indicators of safety and effectiveness in IEI patients...
April 5, 2024: Journal of Clinical Immunology
#40
JOURNAL ARTICLE
Tengku Amatullah Madeehah Tengku Mohd, Wan Yuen Choo, Farizah Hairi, Noran Naqiah Hairi, Nur Sakinah Ahmad, Awatef Amer Nordin, Norliana Ismail, Rajini Sooryanarayana
Social support (SS) has been widely recognized to have a protective effect influencing older adults' emotional and psychological well-being. This study attempted to determine the relationships of structural SS and functional SS on depression and quality of life among the community-dwelling older adults in the rural and Asian context. A cross-sectional study was conducted among 2324 community older adults aged 60 years and above in Kuala Pilah, Malaysia. Participants were recruited via multistage sampling and interviewed face-to-face...
April 5, 2024: Asia-Pacific Journal of Public Health
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