Álvaro Rodríguez-Lescure, Javier Gallego, Pilar Garcia-Alfonso, Bartomeu Massuti, Raúl Márquez, Lourdes Calvo, Pedro Sánchez-Rovira, Antonio Antón, José Ignacio Chacón, Eva Ciruelos, Jose Juan Ponce, Ana Santaballa, Manuel Valladares-Ayerbes, María Rosario Dueñas, Vicente Alonso, Jorge Aparicio, Sara Encinas, Luis Robles, María José Escudero, Rosalía Caballero, Susana Bezares, Juan de la Haba-Rodriguez
BACKGROUND: Retrospective data suggest an association between bevacizumab efficacy and the incidence of arterial hypertension (AHT). Additionally, epigenetic mechanisms have been related to AHT. METHODS: This prospective observational study conducted by GEICAM Spanish Breast Cancer Research Group included metastatic breast (MBC) or colorectal (mCRC) cancer patients treated with bevacizumab-containing chemotherapy as first-line treatment. Blood pressure (BP) levels were measured (conventional and 24-h Holter monitoring) at baseline and up to cycle 3...
April 5, 2024: Clinical & Translational Oncology