keyword
https://read.qxmd.com/read/37641130/process-evaluation-of-paediatric-fellowship-training-programs-at-a-university-hospital-in-pakistan
#21
JOURNAL ARTICLE
Sana Saeed, Prem Chand, Asna Sulaiman, Imran Nisar, Khadija Nuzhat Humayun, Marib Ghulam Rasool Malik, Fyezah Jehan
BACKGROUND: Fellowship programs offer training in a subspecialty focusing on distinct and advanced clinical/academic skills. This advanced postgraduate training allows physicians, who desire a more specialized practice, to further develop clinical, academic, research, and leadership/administrative skills. The Aga Khan University (AKU) is one of the few institutes offering paediatric sub-specialty training in Pakistan. We aimed to evaluate the current Paediatric fellowship programs at AKU...
August 28, 2023: BMC Medical Education
https://read.qxmd.com/read/37605428/psychosocial-impact-of-androgenetic-alopecia-on-men-a-systematic-review-and-meta-analysis
#22
JOURNAL ARTICLE
Hannah Frith, Glen S Jankowski
The adverse psychosocial impact of androgenetic alopecia (AGA) is often framed as an essential motivation for developing efficacious treatments to halt hair loss or promote regrowth, especially since AGA is common among men but does not result in physically harmful or life-limiting consequences. Yet, empirical evidence documenting the impact of AGA on men's psychological wellbeing and quality of life is patchy and has not previously been subject to systematic review. This systemic review and meta-analyses aim to integrate and evaluate evidence regarding the psychosocial impact of AGA on men...
August 21, 2023: Psychology, Health & Medicine
https://read.qxmd.com/read/37587472/health-facilities-preparedness-to-deliver-maternal-and-newborn-health-care-in-kilifi-and-kisii-counties-kenya
#23
JOURNAL ARTICLE
James Orwa, Marleen Temmerman, Lucy Nyaga, Kennedy Mulama, Stanley Luchters
INTRODUCTION: Health facility preparedness is essential for delivering quality maternal and newborn care, minimizing morbidity and mortality by addressing delays in seeking skilled care, reaching appropriate facilities, and receiving emergency care. A rapid assessment of 23 government health facilities in Kilifi and Kisii counties identified poor maternal and newborn indicators in 16 facilities. The Access to Quality Care through Extending and Strengthening Health Systems (AQCESS) project supported these facilities with training, equipment, and referral linkages...
August 16, 2023: BMC Health Services Research
https://read.qxmd.com/read/37567757/role-of-hospital-leadership-in-pandemic-preparedness-experience-at-a-tertiary-hospital-in-kenya-during-the-covid-19-pandemic
#24
JOURNAL ARTICLE
Lucy W Mwangi, William Macharia, Benjamin W Wachira, Jemimah Kimeu, Boniface Mativa, Lukoye Atwoli
INTRODUCTION: Pandemic preparedness refers to being ready for, responding to and recovering from public health crises, and is integral for health security. Hospital leadership is a critical building block of an effective healthcare system, providing policy, accountability and stewardship in a health crisis. OBJECTIVES AND METHODS: We aimed to describe the leadership and governance structures put in place at the Aga Khan University Hospital, Nairobi, a private not-for-profit tertiary healthcare facility, following the COVID-19 pandemic...
August 11, 2023: BMJ leader
https://read.qxmd.com/read/37491103/paksurg-1-determining-the-epidemiology-and-risk-factors-of-surgical-site-infections-in-pakistan-a-multicentre-prospective-cohort-study
#25
JOURNAL ARTICLE
(no author information available yet)
INTRODUCTION: Surgical site infections (SSIs) are among the the most common postoperative complications, despite being highly preventable. Multiple studies have explored the incidence and risk factors of SSIs globally. However, nationally representative data capable of informing evidence-based guidelines remain limited in Pakistan. Hence, the aim of this study is to identify the incidence and risk factors of developing SSIs following surgery and to explore existing SSI prevention practices in Pakistan...
July 25, 2023: BMJ Open
https://read.qxmd.com/read/37480944/pesticides-in-sediments-from-magdalena-river-colombia-are-linked-to-reproductive-toxicity-on-caenorhabditis-elegans
#26
JOURNAL ARTICLE
Lesly Tejeda-Benítez, Katia Noguera, Diana Aga, Jesús Olivero-Verbel
Pesticides are prevalent pollutants found in river sediments in agricultural regions worldwide, leading to environmental pollution and toxic effects on biota. In this study, twenty sediment samples were collected from the Magdalena River in Colombia and analyzed for forty pesticides. Methanolic extracts of the sediments were used to expose Caenorhabditis elegans for 24 h, evaluating the effects on its reproduction. The most abundant pesticides found in Magdalena River sediments were atrazine, bromacil, DDE, and chlorpyrifos...
July 20, 2023: Chemosphere
https://read.qxmd.com/read/37469056/pain-treatment-services-a-national-survey-of-tertiary-care-hospitals-in-pakistan
#27
JOURNAL ARTICLE
Usama Ahmed, Gauhar Afshan
OBJECTIVE: To quantify pain services in Pakistan and classify them according to the International Association for the Study of Pain guidelines. METHODS: The study was conducted at the Aga Khan University, Karachi, from January to June 2022, and comprised data of all public and private tertiary care hospitals anywhere in Pakistan that were registered with the Pakistan Medical Council till November 25, 2021. Data was collected using a predesigned Google form. Data was obtained primarily via email and secondarily by a phone call in a structured format...
July 2023: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/37449475/filac%C3%A2-procedure-for-highly-selected-anal-fistula-patients-indications-safety-and-efficacy-from-an-observational-study-at-a-tertiary-referral-center
#28
JOURNAL ARTICLE
Lara Blanco Terés, Elena Bermejo Marcos, Carlos Cerdán Santacruz, Alba Correa Bonito, Ana Rodríguez Sanchez, María Chaparro, Javier P Gisbert, Javier García Septiem, Elena Martín-Pérez
BACKGROUND: The ideal clinical profile of patients or fistula features for fistula laser closure (FiLaC®) technique remain to be established. The aim of the present study was to analyze clinical outcomes and the safety profile of FiLaC® in search for an ideal setting for this technique. METHODS: Retrospective observational study from prospective database including all consecutive patients operated for anal fistula (AF) with FiLaC® in the coloproctology unit of a tertiary referral center between October 2015 and December 2021...
July 14, 2023: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/37363595/novel-vs-modified-platelet-rich-plasma-therapy-for-hair-loss-treatment-a-systematic-review-and-meta-analysis
#29
JOURNAL ARTICLE
Kaneez Fatima, Haziq Ovais, Zainab Anwar, Maaz Abdul Latif Motan, Maaz Masood Khan, Aly H Khowaja, Altamash Shahriyar Ghazanfar, Muhammad A Khalid, Ayesha Jamil, Yahya Ismail Mujtaba, Sahil Kumar, Ahmed M Rashid
UNLABELLED: Platelet-rich plasma (PRP) therapy, is a stand-alone therapy or is used in combination with other treatments for the treatment of androgenic alopecia. The purpose of this meta-analysis was to compare the improvement in hair density seen, when PRP was used alone and when used as an adjunct. METHODS: Conforming to systematic review and meta-analysis recommendations, we performed a meta-analysis of relevant articles in multiple databases, from inception till May 2022...
June 2023: Annals of Medicine and Surgery
https://read.qxmd.com/read/37333176/non-endoscopic-esophageal-sampling-device-and-biomarker-panel-for-detection-of-barrett-s-esophagus-be-and-esophageal-adenocarcinoma-eac
#30
Helen R Moinova, Suman Verma, John Dumot, Ashley Faulx, Prasad G Iyer, Marcia Irene Canto, Jean S Wang, Nicholas J Shaheen, Prashanthi N Thota, Lishan Aklog, Joseph E Willis, Sanford D Markowitz, Amitabh Chak
BACKGROUND: We previously reported an encapsulated balloon (EsoCheck TM , EC), which selectively samples the distal esophagus, that coupled with a two methylated DNA biomarker panel (EsoGuard TM , EG), detected Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC), with a sensitivity and specificity of 90.3% and 91.7%, respectively. This previous study utilized frozen EC samples. AIM: To assess a next generation EC sampling device and EG assay that utilizes a room temperature sample preservative to enable office-based testing...
June 10, 2023: medRxiv
https://read.qxmd.com/read/37311888/acid-exposure-time-better-predicts-outcomes-following-anti-reflux-surgery-than-demeester-score
#31
JOURNAL ARTICLE
Julia R Amundson, Haris Zukancic, Kristine Kuchta, Christopher J Zimmermann, Vanessa N VanDruff, Stephanie Joseph, Simon Che, Shun Ishii, H Mason Hedberg, Michael B Ujiki
BACKGROUND: Criteria to diagnose gastroesophageal reflux disease (GERD) vary. The American Gastroenterology Association (AGA) 2022 Expert Review on GERD focuses on acid exposure time (AET) rather than DeMeester score from ambulatory pH testing (BRAVO). We aim to review outcomes following anti-reflux surgery (ARS) at our institution, grouped by differing criteria for the diagnosis of GERD. METHODS: A retrospective review of a prospective gastroesophageal quality database was performed for all patients undergoing evaluation for ARS with preoperative BRAVO ≥ 48 h...
August 2023: Surgical Endoscopy
https://read.qxmd.com/read/37235796/erratum-eyestalk-ablation-to-increase-ovarian-maturation-in-mud-crabs
#32
JOURNAL ARTICLE
(no author information available yet)
An erratum was issued for: Eyestalk Ablation to Increase Ovarian Maturation in Mud Crabs. The Introduction, Protocol, Discussion and References were updated. The forth sentence in the third paragraph of the Introduction has been updated from: The eyestalk ablation protocol in this work minimizes stress by using fully sedated crabs and minimizes physical injury to personnel from crab bites.  to: The eyestalk ablation protocol in this work minimizes stress by using fully anesthetized crabs and minimizes physical injury to personnel from crab bites...
May 26, 2023: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/37218222/appropriateness-of-radiographic-imaging-ordered-by-emergency-physicians-a-knowledge-based-survey
#33
JOURNAL ARTICLE
Abdul Ahad Chhotani, Sannia Perwaiz Iqbal, Emaduddin Siddiqui
OBJECTIVE: To assess the knowledge of physicians working in the emergency department in choosing appropriate diagnostic imaging in different clinical scenarios. METHODS: The cross-sectional study was conducted at the Emergency Department of the Aga Khan University Hospital, Karachi, from January 3 to July 2, 2018, and comprised registered medical officers, residents, and consultants of either gender involved in emergency care decision-making. Data was collected using a structured questionnaire that had 10 clinical scenarios based on the American College of Radiology Appropriateness Criteria guidelines...
May 2023: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/37212422/a-combined-dna-rna-based-next-generation-sequencing-platform-to-improve-the-classification-of-pancreatic-cysts-and-early-detection-of-pancreatic-cancer-arising-from-pancreatic-cysts
#34
JOURNAL ARTICLE
Marina N Nikiforova, Abigail I Wald, Daniel M Spagnolo, Melissa A Melan, Maria Grupillo, Yi-Tak Lai, Randall E Brand, Anne Marie O'Broin-Lennon, Kevin McGrath, Walter G Park, Patrick R Pfau, Patricio M Polanco, Nisa Kubiliun, John DeWitt, Jeffrey J Easler, Aamir Dam, Shaffer R Mok, Michael B Wallace, Vivek Kumbhari, Brian A Boone, Wallis Marsh, Shyam Thakkar, Kimberly J Fairley, Elham Afghani, Yasser Bhat, Sanjay Ramrakhiani, John Nasr, Wasseem Skef, Nikhil R Thiruvengadam, Asif Khalid, Kenneth Fasanella, Jennifer Chennat, Rohit Das, Harkirat Singh, Savreet Sarkaria, Adam Slivka, Charles Gabbert, Tarek Sawas, Thomas Tielleman, Hendrikus Dutch Vanderveldt, Anna Tavakkoli, Lynette M Smith, Katelyn Smith, Phoenix D Bell, Ralph H Hruban, Alessandro Paniccia, Amer Zureikat, Kenneth K Lee, Melanie Ongchin, Herbert Zeh, Rebecca Minter, Jin He, Yuri E Nikiforov, Aatur D Singhi
OBJECTIVE: We report the development and validation of a combined DNA/RNA next-generation sequencing (NGS) platform to improve the evaluation of pancreatic cysts. BACKGROUND AND AIMS: Despite a multidisciplinary approach, pancreatic cyst classification, such as a cystic precursor neoplasm, and the detection of high-grade dysplasia and early adenocarcinoma (advanced neoplasia) can be challenging. Next-generation sequencing of preoperative pancreatic cyst fluid improves the clinical evaluation of pancreatic cysts, but the recent identification of novel genomic alterations necessitates the creation of a comprehensive panel and the development of a genomic classifier to integrate the complex molecular results...
May 22, 2023: Annals of Surgery
https://read.qxmd.com/read/37187556/quality-of-capsule-endoscopy-reporting-in-patients-referred-for-double-balloon-enteroscopy
#35
JOURNAL ARTICLE
Joshua Lee, Jonathan Reichstein, Iris Vance, Daniel Wild
BACKGROUND: Abnormal video capsule endoscopy (VCE) findings often require intervention with double balloon enteroscopy (DBE). Accurate VCE reporting is important for procedural planning. In 2017 the American Gastroenterological Association (AGA) published a guideline that included recommended elements for VCE reporting. The aim of this study was to examine adherence to the AGA reporting guidelines for VCE. METHODS: The medical records of all patients who underwent DBE at a tertiary academic center between February 1, 2018, and July 1, 2019, were retrospectively reviewed to identify the VCE report that prompted DBE...
April 2023: Gastroenterology Research
https://read.qxmd.com/read/37170570/gender-differences-in-the-authorship-of-global-major-gastroenterology-society-guidelines
#36
JOURNAL ARTICLE
Shiqi Li, Bei Luo, Jieyu Peng, Muhan Lü, Yan Peng, Xiaowei Tang
BACKGROUND: Gender differences remain a serious issue in the gastroenterology field, which negatively affect the career success and academic advancement of female gastroenterologists. In this study, we aim to identify gender differences in the authors of global major Gastroenterology Society guidelines. METHODS: We included six associations and collected guidelines published between 2003 and 2022. The genders of authors were determined and recorded for each guideline...
May 12, 2023: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/37151428/tailoring-of-neurosurgical-practice-during-covid-19-in-a-developing-country-insights-gained-and-a-way-forward
#37
REVIEW
Mustafa Mushtaq Hussain, Syeda Alisha Ali Zaida, Mujtaba Khalil, Waqas Baqai, Altaf Ali Laghari, Ehsan Bari
BACKGROUND: The coronavirus disease-19 pandemic has aggravated the already neglected neurosurgical specialty in developing countries with a mounting shortage of specialists, long queues of operative patients, and a lack of adequate critical care units. METHODS: We have reviewed the innovative strategies adopted for maintaining an optimal surgical practice while ensuring team safety at the Aga Khan University Hospital, Karachi Pakistan. RESULTS: There is already a scarcity of resources in developing countries...
2023: Surgical Neurology International
https://read.qxmd.com/read/37113818/unconventional-but-effective-breaking-through-ibs-d-clinical-practice-guidelines-correspondence
#38
JOURNAL ARTICLE
Omer Ahmed Shaikh, Gulrukh Shaikh, Rameel Muhammad Aftab, Haisum Baktashi, Irfan Ullah, Muhammad Sohaib Asghar
Irritable Bowel Syndrome (IBS) is a chronic, one of the commonest and persistent gastrointestinal (GI) disorder. Previously, the management plan for IBS-D included enhancing awareness; first line treatment included an increased dietary fiber intake, opioids for diarrhea and antispasmodics for pain management. A recent treatment guideline by the American Gastroenterology Association (AGA) suggests a modified approach to treating patients with IBS-D. Eight drug recommendations were made, and a set of instructions on when to employ which medication was devised...
April 2023: Annals of Medicine and Surgery
https://read.qxmd.com/read/37082451/current-management-of-gastro-oesophageal-reflux-disease-treatment-costs-safety-profile-and-effectiveness-a-narrative-review
#39
REVIEW
Tahmina Lata, Jodie Trautman, Philip Townend, Robert B Wilson
BACKGROUND: The purpose of this study was to review the current management of gastro-oesophageal reflux disease (GORD), including treatment costs, safety profile and effectiveness. METHODS: A literature review was performed of randomized-controlled trials, systematic reviews, Cochrane reports and National/Societal guidelines of the medical, endoscopic and surgical management of GORD. Proton pump inhibitor (PPI) prescribing patterns and expenditure were reviewed in different countries, including Australia, Canada, New Zealand, UK and USA...
2023: Gastroenterology Report
https://read.qxmd.com/read/37061897/aga-clinical-practice-update-on-the-diagnosis-and-management-of-extraesophageal-gastroesophageal-reflux-disease-expert-review
#40
JOURNAL ARTICLE
Joan W Chen, Marcelo F Vela, Kathryn A Peterson, Dustin A Carlson
DESCRIPTION: The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update is to review the available evidence and expert advice regarding the clinical management of patients with suspected extraesophageal gastroesophageal reflux disease. METHODS: This article provides practical advice based on the available published evidence including that identified from recently published reviews from leading investigators in the field, prospective and population studies, clinical trials, and recent clinical guidelines and technical reviews...
June 2023: Clinical Gastroenterology and Hepatology
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