Emmanuel Kokori, Gbolahan Olatunji, Rosemary Komolafe, Ikponmwosa Jude Ogieuhi, Babajide Oyebiyi, Irene Ajayi, Ifeanyichukwu Muogbo, Bonaventure Ukoaka, Owolabi Samuel, Nicholas Aderinto
Group B streptococcus (GBS) poses a significant threat to neonates, leading to morbidity and mortality. Intrapartum antibiotics, although effective, have limitations, prompting the exploration of maternal vaccination. This study reviews the current evidence for maternal GBS vaccination in the prevention of early-onset GBS disease in newborns. A search on Google Scholar, PubMed, and Scopus identified studies assessing the impact of maternal GBS vaccination on early-onset GBS disease. Inclusion criteria comprised English-language clinical trials or observational studies...
March 6, 2024: International Journal of Gynaecology and Obstetrics