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Rosemary Extract

Simona Jancikova, Ewelina Jamróz, Piotr Kulawik, Joanna Tkaczewska, Dani Dordevic
The study investigated the active and intelligent properties of films based on furcellaran (FUR), gelatin hydrolysate (GELH) and rosemary extract (from fresh leaves (FRE) and dry leaves (DRE)). Rosemary extracts were blended with FUR/GELH film forming solution at different three concentrations (5, 10, 20%). Analyzing the ζ-potential dependences of complexation polysaccharide-protein hydrolysate, we selected optimal ratio for the film formation. The introduction of rosemary extracts into FUR/GELH films increased thickness, water content and tensile strength...
March 7, 2019: International Journal of Biological Macromolecules
Jesús García Díaz, Emmy Tuenter, Julio Cesar Escalona Arranz, Gabriel Llauradó Maury, Paul Cos, Luc Pieters
ETHNOPHARMACOLOGICAL RELEVANCE: Leaves of Croton linearis, known as "rosemary", are widely used in folk medicine in Caribbean countries to treat fever and colds (associated to infections). AIM OF THE STUDY: To evaluate the in vitro antimicrobial activity of extracts and fractions derived from C. linearis leaves. MATERIALS AND METHODS: Bioassay-guided fractionation and isolation of compounds from an ethanolic extract of C. linearis, using flash chromatography and semi-preparative HPLC-DAD-MS (High Performance Liquid Chromatography - Diode Array Detection - Mass Spectrometry)...
March 5, 2019: Journal of Ethnopharmacology
Katharina Groten, Alessandra Marini, Susanne Grether-Beck, Thomas Jaenicke, Sally H Ibbotson, Harry Moseley, James Ferguson, Jean Krutmann
BACKGROUND: Our previous double-blinded, placebo-controlled cross-over study indicated that a nutritional supplement named lycopene-rich tomato nutrient complex (TNC) can protect from UVA1-induced (340-400 nm) and UVA- (320-400 nm)/UVB-induced (280-320 nm) upregulation of molecular markers associated with oxidative stress, inflammation, and ageing. OBJECTIVES: in the current double-blind, randomized, placebo-controlled multicenter study, we analyze whether a similar, synergistic carotenoid-rich TNC can protect from broadband UVB-induced threshold erythema formation assessed as increase in minimal erythemal dose (MED) reading, the intensity of erythema formation, and the upregulation of molecular markers associated with inflammation and immunosuppression, and whether this correlates with carotenoid blood levels...
March 5, 2019: Skin Pharmacology and Physiology
L N Leal, M J Jordán, J M Bello, J Otal, L A Den Hartog, W H Hendriks, J Martín-Tereso
BACKGROUND: Due to the growing public concern regarding the addition of chemical antioxidants to foods, focus has shifted towards natural alternatives. Because of their antioxidant potential, culinary herbs and spices have long been used to extend the shelf-life of foods. However, a better understanding of the fate of these products following intake, is required to assess their use in lamb diets. RESULTS: Two hundred eighty-eight Rasa Aragonesa male lambs (70 days old) were supplemented (5...
February 28, 2019: Journal of the Science of Food and Agriculture
Leyla Alizadeh, Khadije Abdolmaleki, Kooshan Nayebzadeh, Reyhane Shahin
The purpose of this study was to investigate the effects of tocopherol, rosemary essential oil and ferulago on oxidative stability of mayonnaise during storage. Their efficacy was also compared with tertiary butylhydroquinone (TBHQ) and the control group. During the primary oxidation stage, tocopherol was more efficient than TBHQ, while in the secondary oxidation stage it was the same as other antioxidants. At end of storage, samples with added rosemary essential oil and ferulago extract showed peroxide value (2...
July 1, 2019: Food Chemistry
Mirosława Karpińska-Tymoszczyk, Anna Draszanowska
The effect of oil-soluble rosemary extract, sodium erythorbate and their mixture, and the influence of packaging method (air and vacuum packaging) on the quality of cooked turkey meatballs stored at -20 ℃ was determined. The smallest changes in malondialdehyde content were observed in samples with the addition of the natural antioxidant regardless of the packaging method. The mixture of synthetic and natural antioxidants was more effective in retarding lipid oxidation than the synthetic antioxidant, and more desirable results were observed in vacuum-packaged samples than in air-packaged samples...
February 20, 2019: Food Science and Technology International
Ana Maria Furkima, Roberta Gonçalves da Silva, Gabriela Vanin, Rosemary Martino
INTRODUCTION: Temporal features of swallowing physiology vary with age in healthy normals and have the potential to impact swallow safety and efficiency in patients with dysphagia. We conducted a meta-analysis to assess the relation between temporal features of swallowing with penetration, aspiration and residue in adult patients with dysphagia regardless of etiology. METHODS: Operational definitions of relevant terms were defined a priori. A search of 5 databases was conducted to November 2016 without restriction to language...
February 9, 2019: NeuroRehabilitation
Muna A AbuDalo, Ismaeel R Al-Mheidat, Alham W Al-Shurafat, Colleen Grinham, Vinka Oyanedel-Craver
Background: Silver nanoparticles (AgNPs) have attracted great attention due to their outstanding electrical, optical, magnetic, catalytic, and antimicrobial properties. However, there is a need for alternative production methods that use less toxic precursors and reduce their undesirable by-products. Phyto-extracts from the leaves of olive and rosemary plants can be used as reducing agents and (in conjunction with Tollens' reagent) can even enhance AgNP antimicrobial activity. Methods: Conditions for the proposed hybrid synthesis method were optimized for olive leaf extracts (OLEs) and rosemary leaf extracts (RLEs)...
2019: PeerJ
Almudena Pérez-Sánchez, Enrique Barrajón-Catalán, Verónica Ruiz-Torres, Luz Agulló-Chazarra, María Herranz-López, Alberto Valdés, Alejandro Cifuentes, Vicente Micol
Colorectal cancer is the third most common diagnosed cancer globally. Although substantial advances have been obtained both in treatment and survival rates, there is still a need for new therapeutical approaches. Natural compounds are a realistic source of new bioactive compounds with anticancer activity. Among them, rosemary polyphenols have shown a vast antiproliferative capacity against colon cancer cells in vitro and in animal models. We have investigated the antitumor activity of a rosemary extract (RE) obtained by using supercritical fluid extraction through its capacity to inhibit various signatures of cancer progression and metastasis such as proliferation, migration, invasion and clonogenic survival...
January 28, 2019: Scientific Reports
Yu-Zhu Wang, Sheng-Yao Wang, Shih-Guei Fu, Deng-Jye Yang, Yu-Shan Yu, Jr-Wei Chen, Yi-Chen Chen
BACKGROUND: The lipid peroxidation is a major quality degradation in an omega-3 (ω-3) fatty-acid fortified surimi-like meat product upon the storage. Currently, the usage of label-friendly alternatives to synthetic antioxidants is encouraged in the industry. Hence, we aimed to examine the possibility of hurdle-technology concept, by using rosemary extracts obtained by 80% ethanol solution extraction (REs) and dry ice (DI) which contain a plenty of polyphenol and can create a cryogenic environment, respectively, on the physicochemical stabilities of ω-3 fatty-acid fortified meat products after manufacture and storage period...
January 24, 2019: Journal of the Science of Food and Agriculture
Kelly J Figueroa-Lopez, António A Vicente, Maria A M Reis, Sergio Torres-Giner, Jose M Lagaron
In this research, the antibacterial and antioxidant properties of oregano essential oil (OEO), rosemary extract (RE), and green tea extract (GTE) were evaluated. These active substances were encapsulated into ultrathin fibers of poly(3-hydroxybutyrate- co -3-hydroxyvalerate) (PHBV) derived from fruit waste using solution electrospinning, and the resultant electrospun mats were annealed to produce continuous films. The incorporation of the active substances resulted in PHBV films with a relatively high contact transparency, but it also induced a slightly yellow appearance and increased the films opacity...
January 23, 2019: Nanomaterials
Yuzo Nishizaki, Naoko Masumoto, Kaori Nakajima, Kyoko Ishizuki, Taichi Yamazaki, Miho Kuroe, Masahiko Numata, Toshihide Ihara, Atsuko Tada, Naoki Sugimoto, Kyoko Sato
We have been developing a high-performance liquid chromatography/photodiode array (HPLC/PDA) employing relative molar sensitivities (RMSs) and adopted it to the accurate quantification of carnosol (CL) and carnosic acid (CA) which are the antioxidants in rosemary extract. The method requires no references of CL or CA and instead uses RMSs with respect to diphenylamine (DPA) whose certified reference material is available from a reagent manufacturer. The molar and response ratios of the analytes to the reference in an artificial mixture of them were determined using 1 H-quantitative nuclear magnetic resonance spectroscopy (1 H-qNMR) and HPLC/PDA at a wavelength of 284 nm under isocratic condition, respectively, and then RMSs were calculated to be 0...
January 22, 2019: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Penghui Li, Ailing Liu, Yinhua Li, Bin Yuan, Wenjun Xiao, Zhonghua Liu, Sheng Zhang, Haiyan Lin
The safety, efficacy and stability of natural antioxidants have been the focus of research in the food industry, with the aim of rapidly analyzing and controlling the quality of rosemary and its extracts, a novel analytical method involving high-performance liquid chromatography with evaporative light scattering detection (HPLC-ELSD) was developed for the simultaneous determination of rosmarinic acid, carnosol, carnosic acid, oleanolic acid and ursolic acid in rosemary. Chromatographic separation was conducted with gradient elution mode by using a Zorbax SB-C18 column (4...
January 17, 2019: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Jarmo-Charles J Kalinski, Samantha C Waterworth, Xavier Siwe Noundou, Meesbah Jiwaji, Shirley Parker-Nance, Rui W M Krause, Kerry L McPhail, Rosemary A Dorrington
The temperate marine sponge, Tsitsikamma favus , produces pyrroloiminoquinone alkaloids with potential as anticancer drug leads. We profiled the secondary metabolite reservoir of T. favus sponges using HR-ESI-LC-MS/MS-based molecular networking analysis followed by preparative purification efforts to map the diversity of new and known pyrroloiminoquinones and related compounds in extracts of seven specimens. Molecular taxonomic identification confirmed all sponges as T. favus and five specimens (chemotype I) were found to produce mainly discorhabdins and tsitsikammamines...
January 16, 2019: Marine Drugs
Hyeain Lee, Rosemary Ahn, Tae Hyun Kim, Euna Han
This paper assesses the relationship between obesity and the job market by focusing on young adults early on in their careers, while considering the factor of gender and the individuals' job qualifications. This study extracted data on high school students for four years from the Korean Education and Employment Panel (from 2010 to 2013), a nationally representative dataset comprising of 2000 middle school students and 4000 high school seniors. The individual-level fixed effects were controlled using conditional logistic regression models and an ordinary least squares model...
January 7, 2019: International Journal of Environmental Research and Public Health
Sophie Epstein, Emmert Roberts, Rosemary Sedgwick, Katie Finning, Tamsin Ford, Rina Dutta, Johnny Downs
INTRODUCTION: Schools have an important role in recognising and preventing self-harm and suicidal behaviour in their students, however little is known about which educational factors are associated with heightened risk. We will systematically review the existing evidence on two key educational performance indicators that are routinely collected by school administrative systems: school attendance and exclusion. We will investigate their association with self-harm and suicidal behaviour in school-age children and adolescents...
December 14, 2018: BMJ Open
David López-Romero, Jeannett A Izquierdo-Vega, José Antonio Morales-González, Eduardo Madrigal-Bujaidar, Germán Chamorro-Cevallos, Manuel Sánchez-Gutiérrez, Gabriel Betanzos-Cabrera, Isela Alvarez-Gonzalez, Ángel Morales-González, Eduardo Madrigal-Santillán
Cancer is one of the leading causes of death worldwide. The agents capable of causing damage to genetic material are known as genotoxins and, according to their mode of action, are classified into mutagens, carcinogens, or teratogens. Genotoxins are also involved in the pathogenesis of several chronic degenerative diseases, including hepatic, neurodegenerative, and cardiovascular disorders; diabetes; arthritis; cancer; chronic inflammation; and ageing. In recent decades, researchers have found novel bioactive phytocompounds able to counteract the effects of physical and chemical mutagens...
December 10, 2018: Nutrients
Rosemary Townsend, Filomena Sileo, Linden Stocker, Hafsah Kumbay, Patricia Healy, Sanne Gordijn, Wessel Ganzevoort, Irene Beune, Ahmet Baschat, Louise Kenny, Frank Bloomfield, Mandy Daly, Declan Devane, Aris Papageorghiou, Asma Khalil
BACKGROUND: Fetal growth restriction (FGR) contributes to stillbirth, prematurity, neonatal and infant mortality and morbidity. Although FGR is well known to be associated with adverse outcomes for the mother and offspring, effective interventions for the prevention of FGR are yet to be established. The majority of pregnancies complicated by FGR are not detected antenatally and there are limited effective interventions for established FGR. Trials reporting interventions for the prevention and treatment of FGR may be limited by heterogeneity in the underlying pathophysiology...
December 6, 2018: Ultrasound in Obstetrics & Gynecology
Yuwei Wang, Delin Qi, Shulin Wang, Xiaohai Cao, Ying Ye, Yourui Suo
Differences in the content of nine phenols and the antioxidant capacity of Ribes stenocarpum Maxim (RSM) fruits at different stages of maturity were investigated, and the extraction process of polyphenols from RSM was also optimized using Box-Behnken design method. Results showed that the content of the nine phenols varied considerably at different ripening stages; catechin, chlorogenic acid, coumaric acid, and ferulic acid were abundant in immature fruits but decreased with fruit ripening, whereas the levels of rosemary acid and querctin acid were low in immature fruits and increased with time, reaching the highest value after the fruit was completely mature...
November 30, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Houda Hamed, Salha Boulila, Ferdaws Ghrab, Rim Kallel, Tahia Boudawara, Abdelfattah El Feki
The present study aimed to evaluate the performance effect of aqueous extract of Rosmarinus officinalis (AERO) against the kidney toxicity induced by CCl4 in mice. The results showed that the renal damage induced by CCl4 was associated with a rise in oxidative stress monitored by a significant increase of TBARS and PCO levels (+89% and +136% respectively, p < .001) and a significant decrease of GSH level (-68%, p < .001) and antioxidants enzymes such as SOD, CAT, and GPX activities (-41.7%, -47...
November 30, 2018: Archives of Physiology and Biochemistry
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